PLAY PODCASTS
🧬 Jacob Glanville - Centivax - Part 3 | Building a Biotech without Venture Capital | Picking Lab Space & Company Growth | Equipment Leasing & Runway/Cash Flow Maximization | Process Drift & ā€œThe Respiration Modelā€
Episode 3

🧬 Jacob Glanville - Centivax - Part 3 | Building a Biotech without Venture Capital | Picking Lab Space & Company Growth | Equipment Leasing & Runway/Cash Flow Maximization | Process Drift & ā€œThe Respiration Modelā€

Jacob is the Founder, CEO, & President of Centivax and was formerly the Co-founder, CEO, and President of Distributed Bio. Join us as we sit down with Jake, discussing his three-part plan for building Distributed Bio without traditional venture capital, how reality differed from the plan, and how the acquisition by Charles River Laboratories occurred. Learn more about his thoughts on natural team growth and how to handle process drift. Hear Jake’s view on how equipment leasing provided a solution for growing a business when cash was tight and needed for investing in internal operations. Discover Jake’s insight into what he calls ā€œthe respiration modelā€ of leadership, balancing hierarchical and organic structures to promote organization and innovation. Hear more about his experience spinning out Centivax.

The Biotech Startups Podcast Ā· Excedr

May 3, 202334m 35s

Audio is streamed directly from the publisher (media.fame.so) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.

Show Notes

Part 3 of 4.

My guest for this week’s episode is Jacob Glanville. Jacob is the Founder, CEO, & President of Centivax and was formerly the Co-founder, CEO, and President of Distributed Bio.

Join us as we sit down with Jake, discussing his three-part plan for building Distributed Bio without traditional venture capital, how reality differed from the plan, and how the acquisition by Charles River Laboratories occurred.

Learn more about his thoughts on natural team growth and how to handle process drift. Hear Jake’s view on how equipment leasing provided a solution for growing a business when cash was tight and needed for investing in internal operations.

Discover Jake’s insight into what he calls ā€œthe respiration modelā€ of leadership, balancing hierarchical and organic structures to promote organization and innovation. Hear more about his experience spinning out Centivax.

Please enjoy my conversation with Jake Glanville.

Find Our Guest, Jacob Glanville, at these links: 
https://www.linkedin.com/in/jacobglanville 
https://twitter.com/CurlyJungleJake 
https://www.centivax.com
https://twitter.com/centivax 


Find Our Host, Jon Chee, at these links: 
https://www.linkedin.com/in/jonchee
https://www.excedr.com

Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/ 
Youtube: https://www.youtube.com/@excedr 
Instagram: https://www.instagram.com/excedr_inc 
Twitter: https://twitter.com/ExcedrInc 
Facebook: https://www.facebook.com/excedr 
TikTok: https://www.tiktok.com/@excedr 
Podcast Website: https://www.thebiotechstartupspodcast.com/ 

Timestamps:

00:00 Intro
01:47 Episode start
02:11 Building a biotech without traditional venture capital
05:29 How reality differed from the 3-part plan
07:25 The difficulties of having to get lab space
09:16 Natural team growth & the relationship with the University of San Francisco
12:30 Equipment leasing, how to grow a business when cash is tight and needed for growth
14:40 Jake’s challenges & experiences that were the toughest, managing your partners
17:01 The process drift problem & implementing a buddy system
18:56 Realizing what you really need, when to spend vs. save
20:30 The biotech VC ramp, striking a balance between the hierarchical vs. organic models
22:05 ā€œThe respiration modelā€ of leadership
24:20 Moving on to the next thing, what made the SuperHuman-2.0 special
28:00 Spinning out Centivax, winning the Gates Foundation Award
31:10 Focusing on what is most important, the importance of the universal vaccine
33:15 Outro

Enriched Notes:

Topics Mentioned:
Distribute Bio https://www.criver.com/charles-river-acquired-distributed-bio
Centivax https://www.centivax.com/ 
Synthetic Libraries https://pubmed.ncbi.nlm.nih.gov/22735944/
Polyspecificity https://pubmed.ncbi.nlm.nih.gov/22903677/
Broad Oak https://broadoak.com/ 
Arpa H https://www.nih.gov/arpa-h 
Jlabs https://jnjinnovation.com/jlabs 
Poisson distribution https://en.wikipedia.org/wiki/Poisson_distribution 
Charles River Laboratories https://en.wikipedia.org/wiki/Charles_River_Laboratories
SuperHuman Antibody Library https://www.criver.com/products-services/discovery-services/antibody-discovery-services/biologics-discovery-and-protein-engineering/antibody-discovery/superhuman-antibody-library-discovery

People Mentioned:
Sawsan Youssef: https://www.linkedin.com/in/sawsan-youssef-b274b010/
The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.