Episode 99
🧬Barry Ticho - Part 2 | Zebrafish Hearts & Pediatric Cardiology | Balancing Lab Work & Clinical Practice | Navigating Academic Medicine's Challenges | The Draw of Biopharma & Translational Medicine
Part 2 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.
The Biotech Startups Podcast · Excedr
November 28, 202428m 4s
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Show Notes
The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.
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Part 2 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines.
With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas.
Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.
Join us this week to hear about:
- Pioneering research using transparent zebrafish embryos to study cardiac development
- Helping establish the myCHOICE program at University of Chicago
- Managing concurrent roles at Harvard Medical School and Mass General
- Gaining invaluable crisis management experience as a pediatric cardiologist leading emergency resuscitations
- Making the strategic career transition to biopharma to combine basic science with clinical work
Please enjoy Jon’s conversation with Barry Ticho.
Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Find Our Guest, Barry Ticho, at these links:
Find Our Host, Jon Chee, at these links:
Excedr Socials & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Stoke Therapeutics https://www.stoketherapeutics.com/
Verve Therapeutics https://www.vervetherapeutics.com/
University of Chicago https://www.uchicago.edu/en
Harvard Medical School https://hms.harvard.edu/
Boston Children's Hospital https://www.childrenshospital.org/
Massachusetts General Hospital https://www.massgeneral.org/
Northwestern University https://www.northwestern.edu/
Northwestern University https://www.northwestern.edu/
How to Spin Out of Academia: https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup
Breaking into BD as a PhD Student https://www.excedr.com/blog/how-to-break-into-biotech-bd-as-a-phd-student
Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support
Medical Imaging: Modalities & Types of Equipment https://www.excedr.com/blog/medical-imaging-and-radiology-overview
People Mentioned:
Mark Fishman https://www.linkedin.com/in/mark-fishman-1b1368182/
Timestamps:
00:00 Intro
02:16 Transitioning from grad school to Harvard and Boston Children's Hospital
04:19 The importance of rotations and exploring different career paths
06:48 Fascination with cardiac development: From four cells to a complex organ
08:24 Advice on continuous learning and career exploration
10:49 The shift in academia: From textbooks to startups
12:09 Zebrafish research: Transparent insights into cardiac development
14:44 The rewards and challenges of practicing pediatric cardiology
16:57 Learning from brilliant colleagues: "Steel sharpens steel"
18:18 Avoiding comparison: "Comparison is the thief of joy"
20:59 Gaining perspective on emergencies: From cardiac arrests to business crises
23:46 The catalyst for transitioning to industry: Combining science and clinical interests
26:27 The changing landscape of medicine and the appeal of biopharma
27:18 Outro
The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.