Can Creatine Reduce Depression?
Talking With Docs Podcast · Dr. Brad Weening and Dr. Paul Zalzal
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Show Notes
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Is Creatine Just for Muscles? New Study Says No
Creatine is known for building strength — but new research shows it may also reduce symptoms of depression.
In this episode, doctors break down a study where creatine, combined with CBT (cognitive-behavioural therapy), helped improve mental health. It’s safe, accessible, and now showing promise beyond physical performance.
We cover:
- How creatine affects brain function
- What a recent clinical trial revealed
- Whether creatine could support mood and therapy
- Who might benefit and if it's safe to try
If you take creatine or are curious about mental health supplements, this is for you.
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📄 Study Reference: Sherpa NN, et al. Creatine + CBT in depression. Eur Neuropsychopharmacol. 2025;90:28–35. https://doi.org/10.1016/j.euroneuro.2024.10.004
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