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Breaking Barriers in Protein Therapeutics - Dr. Dan Mandell
Episode 408

Breaking Barriers in Protein Therapeutics - Dr. Dan Mandell

Talking Biotech with Dr. Kevin Folta · Colabra

July 29, 202337m 1s

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Show Notes

This is one hot tech discussion!  Protein therapeutics have great potential, but significant limitations to their utility. Dr. Dan Mandell of GRO Biosciences explains how they are using a non-standard library of amino acids to increase protein presentation. Along with glycosylation and other modifications, the proteins are more therapeutically active, as such changes can improve issues like stability and visibility to the immune system. The technologies are being used to design therapeutic solutions for autoimmune diseases, such as myasthenia gravis. This is a technology dense episode that stretches the bounds of molecular biology. 

Topics

peptide therapeuticsglycosylationglycansmyasthenia gravisamino acids