Rheumnow Podcast

JAK Safety -- The Lowdown on Infection: Drs. Kevin Winthrop and Jonathan Kay Infections in ORAL Surveillance: Drs. Kevin Winthrop and Jonathan Kay Infliximab Drug Monitoring in PsA, RA, AxSpA: Dr. Pedro Castillo Lupus and Pregnancy: Dr. Sheila Reyes Secukinumab Effect on CV Risks in PsA, axSpA: Dr. Sheila Reyes

Spondyloarthritis Roundtable Rehash of ACR 2021

Giant Cell Arteritis and Polymyalgia Rheumatic Wrapup: Drs. Calabrese, Liew, Conway and Mackie

Reproductive Health in Rheumatic Diseases: Drs. Bermas, Buyon and Dao

The Expert Gout Panel with Drs. Neogi, Saag, Pillinger, Cush and O'Dell

Tofacitinib and Malignancy Risk: Dr. Seoyoung Kim Potpourri of Biosimilar Trials: Dr. Jonathan Kay Closing a Chapter: Interview with the 84th ACR President 2020-2021, Kathryn Dao

RheumNow Rheumatology Roundup- Drs. Kavanaugh and Cush

TNF Inhibitor Panel Discussion- ACR21 Annual Meeting

Psoriatric Arthritis Panel Discussion- ACR21

RA Panel- Safety, Multimorbidities, Vaccination and the Weather

Glucocorticoids and CV risk in RA: Drs. Aurelie Najm and Jon Giles Might Tofacitinib Reduce Malignancy Risk with Patients with RA? Dr. Jonathan Kay Rheumatic Diseases Can Take your Breath Away: Dr.Janet Pope Best of PsA Day 4 (Tuesday): MACE in PsA: Dr. Rachel Tate Predicting Progression from Psoriasis to PsA: Dr. Robert Chao David Liew Interview Dr. Seoyoung Kim About Tofacitinib and Malignancy Risk. Third Time's the Charm - COVID Vaccination While on Rituximab: Dr. Yuz Yusof Can We Stop Medication in Systemic JIA? Dr. Bella Mehta Day 4 SpA Highlights - Pregnancy in SpA and Drug Monitoring: Dr. Robert Chao

Diagnosing (Bad) VEXAS: The Experts Speak with Drs. Cush, Beck and Ferrada CV Risks and Gout T2T - An Interview with Dr. Seoyoung Kim, Kathryn Dao

Dr. Michelle Petri - Urine Proteome Advances: What Do They Mean? "Doctor, I Can Tell When It's Raining!" - Dr. Aurelie Najm NSAIDS Prevent Heart Attacks in PsA: Dr. Richard Conway Pediatric Psoriatic Arthritis: Dr. Eric Ruderman irAEs: Drs. Cassie Calabrese and David Liew TNFi in axSpA: Dr. Swetha Alexander

Sex, Age and Race/Ethnic Differences in Multimorbidity in Lupus: Drs. Duarte and Mehta Hospitalization Trends in Patients with Psoriatic Arthritis: Dr. Olga Petryna Patient Reported Outcomes in axSpA: Dr. Swetha Alexander Pregnancy Outcomes in PsA, SpA, RA: Dr. Rachel Tate Guselkemab vs. Ustekinumab in PsA: Dr. Richard Conway Medication Preferences in Patients with Psoriatic Arthritis: Dr. Olga Petryna Dr. Michelle Petri - Urine Proteome Advances: What Do They Mean?

Uveitis in AxSpa: Dr. Sheila Reyes ACR Gold Medal Recipient: Dr. Stan Cohen Infection Risk in Offspring Exposed to Biologics: Dr. Rachel Tate Steroids in RA Patients 65 and Older: Dr. Richard Conway Cardiovascular Disease for TNFi vs JAKi: Dr Jon Giles Food for Thought: "ITIS" Diet for Patients with Rheumatoid Arthritis: Dr. Akhil Sood Who gets Methotrexate Induced Nausea and Alopecia? Drs.Ahmad Sherbini and Eric Dein

ACR21 Day 3 Recap- Polypharmacy, New Lupus Drugs, VEXAS, Safety Data

Dr. Janet Pope: RA Conundrums Drs Kathryn Dao, Una Makris and Raymond Yung: Caring for the Older Patient with Rheumatic Disease Dr. Arthur Kavanaugh: FDA Approvals Predictors of TNF Response with Drs. Pope, Dein and Liew The Gift of Gab with Drs. Dein and Liebowitz and Janet Zeide

Drs Jack Cush, Yuz Yusof, Bella Mehta, Olga Petryna, and Rachel Tate Auto-inflammatory Panel

The Respiratory Tract and RA with Drs. Sparks, McDermott and Kronzer Guselkumab Use Improves Anemia in Treatment of PsA: Dr. Robert Chao Ultra Low Doses of Rituximab in RA: Dr. Eric Dein and Nathan den Broeder Uveitis and Prevalence of Psoriasis in axSpA: Dr. Robert Chao

Long Term Steroid Use in RA - Matters of the Heart: Dr. Mrinalini Dey Data on Existing SLE Medications, Patient Centered Outcomes, and Exercise: Dr. Michelle Petri COVID-19 Vaccination in Autoimmune Disease: Drs. Latika Gupta and Sheila Reyes Pulmonary Hypertension in Adult Onset Still's Disease: Dr. Jack Cush MDA in Psoriatic Arthritis: Dr. Rachel Tate CBD in Hand OA and PsA: Dr. Richard Conway

Real Time Monitoring of Disease Activity? There's An App for That: Dr. Akhil Sood CBD and Opioids in Psoriatic Arthritis: Dr. Eric Ruderman Osteoporosis in PsA: Dr. Rachel Tate Type 1 and Type II Lupus — Patient Perspectives: Drs. Bella Mehta and Megan Clowse JAKi Safety: Dr. Ernest Choy with Dr. Aurelie Najm Herpes Zoster and Rheumatoid Arthritis: Dr. Akhil Sood Frailty in Lupus: Dr. Sheila Reyes Geriatric Rheumatology: Improving care of aging patients

First JAKi Failure: What next? Dr. Aurelie Najm: RAPID3 in Psoriatic Arthritis: Dr. Meral El Ramahi Herpes Zoster and Rheumatoid Arthritis with Dr. Akhil Sood JAKi Safety Through the Lens of an Expert: Interview of Dr. Ernest Choy with Dr. Aurelie Najm Emerging Therapies in Psoriatic Arthritis: Drs. Antoni Chan and Oliver FitzGerald

Vitamin D and Omega-3 Fatty Acids Reduce Risk of Autoimmune Diseases: Dr. Chao Health Information Use by SLE Patients: Dr. Sheila Reyes Best of SpA Abstracts Day 2: Dr. Robert Chao Career Advice for Young Rheumatologists: Drs. Janet Pope and Vivian Bykerk Drs Antoni Chan and Oliver FitzGerald: New Therapies in Psoriatic Arthritis

ACR21 Day 2 Recap- CV Risk, Tapering in SpA, Microbiome in PsA, Vit D

Poverty and Length of Hospital Stays for Children with Lupus: Dr. Bella Mehta BBB and CNS Dysfunction in SLE: Dr. Jack Cush Twin Studies on Psoriasis Microbiome: Dr. Robert Chao Are you Aware of COPA Syndrome? Dr. Meral El Ramahi Early Rheumatoid Arthritis: Drs. Vivian Bykerk and Janet Pope TNF Inhibitors Rise to the Top: Drs. Janet Pope and David Liew Cytokines & Chemokines Predict Incident MACE in RA Veterans: Dr. El Ramahi

RheumNow Daily Recap - ACR21

Catching up with Dr. Vivian Bykirk with Dr. Janet Pope Life Lessons with Dr. Vivian Bykirk with Dr. Janet Pope RAPID3 to Monitor Disease Activity in Psoriatic Arthritis, not just RA! with Dr. El Ramahi Several Cytokines & Chemokines Predict Incident MACE in RA veterans! with Dr. El Ramahi Are you Aware of COPA Syndrome? with Dr. El Ramahi TNF Inhibitors Rise to the Top with Drs. Pope and Liew 4

ACR21 Day 2 Recap- Drs Cush, Liew, Alexander, El Merahi, Dey and Chao

SLE Update: Vitamin D and Hydroxychloroquine: Dr. Michelle Petri Frailty and Lupus with Dr. Sheila Reyes Health Disparities: Dr. Artie Kavanaugh BBB and CNS Dysfunction in SLE: Dr. Jack Cush Twin Studies on Psoriasis Microbiome with Dr. Robert Chao Best of SpA Day 2 with Dr. Robert Chao 1 Vitamin D and Omega-3 Fatty Acids Reduce Risk of Autoimmune Diseases with Dr. Chao

Predictors to Flare in SpA: Dr. Antoni Chan Psoriatic Arthritis: What's with Brepocitinib? Dr. Eric Ruderman Radiographic Progression in SpA: Dr. Antoni Chan Does Obesity Play a Role in Biologic Response? Dr. Eric Dein Radiographic Progression in SpA: Dr. Antoni Chan Does Obesity Play a Role in Biologic Response? Dr. Eric Dein Treat to Target in SLE: Dr. Yuzaiful Yusof Best of PSA from Sunday Sessions: Dr. Rachel Tate Updates on New Treatments for SpA: Drs. Antoni Chan and Laura Coates

Hypertension in AS: Drs. Swetha Ann Alexander and Jean Liew Depression in Axial Spondyloarthritis: Dr. Mrinalini Dey Predictors of mortality in RA lung disease? Dr. Meral El Ramahi An Exclusive Interview with Dr. Al Kim (#Wowkim): Dr. Kaythryn Dao Dr. Eric Dein: Can we Use Frax Score in RA Patients?

ACR Day 2 Highlights in Lupus- Drs Dao, Mehta, Yusof, Pope, Reyes and Castillo

Recognizing and Treating Axial Disease in Psoriatic Arthritis: Dr. Pedro Castillo Best of Spondyloarthritis from Day 1: Dr. Robert Chao Treating RA: Does Where You Live Matter? Dr. Mrinalini Dey To Clot or Not to Clot: Drs. Janet Pope and Jeffrey Sparks Best of PsA Saturday: Dr Rachel Tate NrAxSpA progression to AxSpA: Dr. Rachel Tate Pulse Pressure as a Predictor of Carotid Plaque in RA: Dr. Meral El Ramahi Hydroxychloroquine Levels in Type I and 2 Lupus: Drs. Megan Clowse and Bella Mehta

Does RA Begin in the Gut? with Dr. Jonathan Kay Dr. David Liew: 11 Ways to Stay Away From RA Dr. David Liew: Tired of Doing Nothing About Fatigue Lung Now with Drs. Pope and Sparks Perspectives on TNF and RA Day 1 with Dr. Jon Giles

ACR21 Day 1 Recap Panel with Drs. Cush, Najm, Mehta, Yusof, Castillo, Conway

The PROOF Study in AxSpA: Dr. Sheila Reyes Management of Pain in Spondyloarthritis: Dr. Antoni Chan Pregnancy complications in Ankylosis Spondylitis: Dr.Olga Petryna JAKi For Refractory Still’s Disease: Dr. Olga Petryna Sinusitis and Pharyngitis and RA with Dr. Richard Conway Cognitive Function and Rheumatoid Arthritis: Dr. Akhil Sood Interviews Dr. Elena Myasoedova Serum Biomarkers to Distinguish Radiographic Progression in PsA with Dr. Robert Chao

Preventive Window of Opportunity in RA? Dr. Aurelie Najm Iberdomide for Lupus: Dr. Kathryn Dao Increased Risk of MACE in Lupus After Noncardiac Surgery: Dr. Kathryn Dao Peripheral SpA: Dr. Antoni Chan and Dr. Nelly Ziade Complications of Covid19 in Lupus: Dr. Kathryn Dao Dose Tapering of TNFi in AxSpA: Dr. Antoni Chan Dr. Yuzaiful Yusof: Factors Associated with Poor Vaccine Response in Rituximabe-treated Patients

What's Cool and Hot in Vasculitis: Dr. Janet Pope ARIAA Study - Abatacept Reverses ACPA+ Subclinical Arthritis: Dr. Jack Cush MRI Imaging in RA and SpA: Dr. Sheila Reyes Sick Leave, Work Disability in Patients with AxSpA: Dr. Mrinalini Dey PsA Perspectives - IL-23: Dr. Eric Ruderman Patient Clustering Based on Multimorbidity Patterns in RA: Dr. Mrinalini Dey and Dr. Bryant England

COVID in Rheumatologic Disease Patients: Drs. Sparks, Liew, Yazdany and Dao AxSpA: Geographic Prevalence Association with HLA-B27: Dr. Rachel Tate What I'm Looking Forward to at ACR: Dr. Arthur Kavanaugh Fibromyalgianess Glucocorticoid Persistence in RA Patients: Dr. Sheila Reyes

SLE Panel-Learning about Lupus at ACR 2021

Opening Ceremony, Keynote Lecture and Year in Review Discussants: Drs. Jack Cush, Sheila Reyes, Rachel Tate & Kathryn Dao

QD153 - Serologically Active, Clinically Quiescent SLE QD154 - Paradoxical Psoriasis QD155 - Scary Steroids QD156 - How I Treat Rheumatoid Arthritis

Dr Cush reviews the news and kicks off ACR21 learning and how to take in the annual meeting

QD148 - Severe Arthritis Numbers and Associations QD149 - The Thyroid Lump QD150 - Alopecia Rules QD151 - Half Baked Blogs QD152 - Who is Immunosuppressed?

Dr. Jack Cush reviews the news and journal articles from the past week and discusses parent-child rheumatologists pairs

Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com

Dr. Jack Cush reviews the FDA approvals, news and the latest journal articles from the past week on RheumNow.com

Dr Jack Cush reviews the news and journal reports from this past week on RheumNow.com; plus questions & cases from viewers in (#ACA) Ask Cush Anything.

New to RheumNow? Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. In this episode, Dr Jack Cush reviews the news, journal articles and FDA warnings from the past week on RheumNow.com A population based Swedish study of birth records shows that antibiotic exposure in first three years of life to be associated with a future risk of JIA, although infections during fetal life or childhood did not increase risk of JIA. #RheumNow https://t.co/Md0zBm5Txl Alendronate may protect against type 2 Diabetes. Data from National Danish Patient Registry, presented at the EASD meeting compared 160k T2DM & 500k controls, T2DM following alendronate adjusted OR=0.64; 0.62-0.66; ⋗8yrs OR=0.47 https://t.co/RYEZodUZtv Analysis of 508 #RA pts (over 10 yrs) in the BeST study shows joint swelling at baseline resulted in half w/ re-swelling later and significantly increased risk of same joint swelling during follow-up (OR 2.37, 95% CI 2.30 to 2.43, p⋖0.001) https://t.co/a7zH4YRAkq Finnish Pop study 939 #RA pts shows highest healthcare costs linked to high Dz activity & comorbidity. Clusters: C1) young w/ low costs & activity, C2) chronic pain, disability, fatigue, C3) high cost/dz activity, less pain, C4)comorbidities w/ $$$ https://t.co/Azc35zyA9J A longitudinal study from Iceland shows an increasing number of native joint infections (NJI), with iatrogenic, postarthroscopic infections being of particular concern. Read more… https://t.co/j3gzZ9g0QV Case controlled study suggests that intraarticular steroid injections is associated with increased (HR 8.56; 3.29-22.3) risk of rapidly destructive hip disease (RDHD); at a rate of 5.4% (5.1 mos post injx) w/ JSN, osteolysis, fem head collapse https://t.co/grX5bO4495 Biosimilar update: 31 FDA approved biosimilars, but only 60% made it to market. 2015 to 2019, drug spending grew 6.1%, biologic spending grew 14.6%; biologics are 43% of US drug spending. Most biosimilars at ~30% discount. https://t.co/4paYH8yVLQ Study Finds U.S. Generic and Biosimilar Savings Totaled a Record $338 Billion in 2020 https://t.co/hPR0nGd6jp Can I get the INFLUENZA and COVID Vaccines together? The CDC says: "YES...both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine.... ideally get a flu vaccine by the end of October." https://t.co/T49zm6Cxyc MMWR shows the safety of a 3rd (booster) dose of the mRNA vaccine to be same as the 2nd dose AEs. V-safe data on 3rd dose (n=12,591) showed local or systemic effects (79% or 74%) to be same as 2nd dose (78% or 76%) https://t.co/LcD0ARlWJ2 CDC Advises COVID-19 Vaccines for Pregnant Women https://rheumnow.com/news/cdc-advises... U.S. Preventive Services Task Force (USPSTF) reaffirmed its recommendations that pregnant women at a high risk of preeclampsia should take a daily aspirin regimen at the end of the first trimester https://t.co/DiV7p6g8vL Is Acetaminophen Potentially Hazardous in Pregnancy? https://rheumnow.com/news/acetaminoph... #RA patients had an an increased risk of mortality after CABG (HR 1.50; 1.28-1.77); and a higher risk of MI following CABG (HR 1.61; 1.28-2.04). A retrospective Finnish study comparing RA (n= 378) to nonRA patients (n = 7560) https://t.co/cGGsrLs1V2 Early Diastolic Dysfunction in Premenopausal Women with RA https://rheumnow.com/news/early-diast... 108 pts with autoimmune cytopenias (TTP, ITP, AIHA, etc) were given COVID vaccination showing low rate of post-vax flares. Signif HEME decreases in 7.4% of AIHA & ITP; mild decrease in 10% AIHA and 20% ITP, w/ no Rx change https://t.co/OaHILar57z Global SECURE-IBD trial on IBD drugs and COVID shows that severe COVID-19 outcomes were not associated with the use of biologics and mesalamine/sulfasalazine, AZA, 6MP, MTX combo Rx or biologics (TNFi, IL-12/23, IL-23, integrin inhib) https://t.co/MO4i5ngKkr Questions & Cases Approach to dental surgery while on bisphosphonate Recurrent shingles while on adalimumab Myositis after COVID-19 vaccine CONNECT WITH RheumNow ✩ Website - https://rheumnow.com/ ✩ Subscribe @ RheumNow: https://rheumnow.com/user/register ✩ LinkedIn - https://www.linkedin.com/in/john-cush... ✩ RheumNow LinkedIn: https://www.linkedin.com/company/rheu... ✩ Twitter - https://twitter.com/RheumNow Listen | PODCAST Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/4Mjzj5j... Stitcher: https://www.stitcher.com/show/the-rhe... TuneIn: https://tunein.com/podcasts/Health--W... Podbean: https://rheumnow.podbean.com/ Got a Rheumatology question or case for Dr. Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. BackTalk: https://rheumnow.com/submit-podcast-q...

New to RheumNow? Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. In this episode, Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com Study of 435 #SLE pts seen during the pandemic. Comparing those seen F2F vs telemedicine, there was no significant difference in SLE disease activity (by SLEDAI-2K) or SLE flare rates or steroid prescribing between visit types https://bit.ly/39wWoQ6 Encouraging DBRPCT of Rituximab in #PMR: 116 screened, 49 enrolled, 47 completed: 23 on RTX vs 24 on PBO. Steroid-free remission at 21 wks seen with 11/23 (48%) RTX pts vs 5/24 (21%) on PBO (p=0·049). Infusion Rxns: 10 RTX vs 3 PBO); 1 SAE (PE) on RTX https://bit.ly/3lSI0rj Pregnancies exposed to ixekizumab (from Eli Lilly Global Safety Database) found 193 pts with psoriasis, PsA, or axSpA who were IXE exposed. Live births reported for 53.8 and 61.1% of known outcomes. No congenital malformations seen. https://t.co/M1rvCH81hT FDA approves Jakafi for chronic GVHD. Ruxolitinib (Jakafi, Incyte), an oral Janus kinase 1/2 inhibitor, previously received approval for treatment of patients aged 12 years or older with steroid-refractory acute GVHD. https://t.co/isItDebNZ8 Retrosp. review of 10–24 yr olds w/ newly Dx #SLE shows 78% given steroid-sparing DMARDs by year 1; Most (69%) given HCQ & fewer (34%) given other immunosuppressants. Adults less likely to recv immDMARDs @1 yr https://t.co/aLi6FXlMd3 Case controlled study shows CPPD pts have no higher risk for MACE. 23,124 CPPD vs 86,629 non-CPPD, w/ ⋗ 250,000 Pt-Yrs FU. CPPD MACE risk not increased (HR 0.98), but there was incr risk of MI, CVA & acute coronary syndr. https://t.co/pgmZBxTg9O Trade names: Generic PFIZER = Comirnaty; MODERNA= Spikevax Moderna; J&J (pending) https://t.co/MM7XiSCczl Prospective study of 77 RA patients in remission -- ⋗ vax w/ BNT162b2 (BioNTech-Pfizer) (w/ temp D/C of DMARDs per ACR) found a vaccine-related flare rate of 7.8% (6 pts) w/ 5/6 flares after 2nd dose (2.6 days), resolved w/in 2 wks https://t.co/YOL3YVS2ne Dr. Calabrese shares his Delta COVID-19 breakthrough story on the blog today. https://t.co/timjB2YPys BMJ Breakthrough infections from UK QResarch database: Among 6.95 million vaccinated, 74.1% recv two vaccine doses, there were 2031 covid-19 deaths & 1929 hosp admissions; ~4.0% deaths & admissions were ⋗14 days after 2nd dose Addendum: COVID deaths increased w/ age, deprivation, male, Indian & Pakistanis. Highest risk w/ Down’s syndr (HR 12.7), renal transplant (8.1), sickle cell (7.7), Nursing home (4.1), chemotherapy (4.3), HIV/AIDS (3.3), liver cirrhosis (3), CNS dz (2.6) Addendum: Other conditions w/ a 1.2-2 fold higher risk of COVID death (admission) were CKD, hematologic cancer, epilepsy, COPD, CVD, stroke, atrial fibrillation, CHF, thromboembolism, PVD, type 2 diabetes. https://t.co/bbDsb1zLhX Claims case-controlled study shows statin use does not increase the risk of #RA - 32,726 RA and matched controls ; statin use (34 vs 32%) slightly increased RA risk (OR 1.12, 1.06–1.18), but signif lost after correcting for hyperlipidemia https://t.co/EcTlyE1MPx High Comorbidity Rates with Inclusion Body Myositis Guselkumab Treats Axial Disease in Psoriatic Arthritis 11 Drugs That Cause Arthritis https://rheumnow.com/news/11-drugs-ca... Viewer Question – A positive anti ds DNA in the absence of clinical evidence of lupus? CONNECT WITH RheumNow ✩ Website - https://rheumnow.com/ ✩ Subscribe @ RheumNow: https://rheumnow.com/user/register ✩ LinkedIn - https://www.linkedin.com/in/john-cush... ✩ RheumNow LinkedIn: https://www.linkedin.com/company/rheu... ✩ Twitter - https://twitter.com/RheumNow Listen | PODCAST Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/4Mjzj5j... Stitcher: https://www.stitcher.com/show/the-rhe... TuneIn: https://tunein.com/podcasts/Health--W... Podbean: https://rheumnow.podbean.com/ Got a Rheumatology question or case for Dr. Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. BackTalk:https://rheumnow.com/submit-podcast-question-or-comment