Paroxysmal Nocturnal Hemoglobinuria | Oncology Today with Dr Neil Love: Management of Paroxysmal Nocturnal Hemoglobinuria
Research To Practice | Oncology Videos · Dr. Neil Love
July 26, 202342m 42s
Audio is streamed directly from the publisher (traffic.libsyn.com) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
Featuring perspectives from Dr Carlos M de Castro, including the following topics:
- Biology of paroxysmal nocturnal hemoglobinuria (PNH) (0:00)
- Evolution of the PNH treatment landscape (13:07)
- Selection and sequencing of therapies for patients with PNH (18:09)
- Overview and presentation of extravascular hemolysis (23:50)
- Case: A woman in her early 40s with PNH who developed Budd-Chiari syndrome and had an excellent response to C5 inhibition (26:57)
- Case: A woman in her early 40s with a suboptimal response to ecluizumab followed by an excellent response to pegcetacoplan on the PEGASUS trial (34:00)
- Case: A woman in her mid 40s who experienced breakthrough hemolysis with pegcetacoplan and was recently switched to iptacopan (38:40)