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Ocular Toxicities Associated with ADCs and Other Cancer Therapies: Part 2  — An Interview with Dr Neel Pasricha on Adverse Event Management

Ocular Toxicities Associated with ADCs and Other Cancer Therapies: Part 2 — An Interview with Dr Neel Pasricha on Adverse Event Management

Research To Practice | Oncology Videos · Dr. Neil Love

September 16, 202554m 23s

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Show Notes

Featuring an interview with Dr Neel Pasricha, including the following topics:

  • Anatomy and physiology of the cornea; intersection of ophthalmology and oncology for patients receiving antibody-drug conjugates (ADCs) (0:00)
  • Association of corneal toxicities with ADCs (4:56)
  • Dose and schedule modifications to mitigate ocular toxicities associated with belantamab mafodotin and other ADCs (9:02)
  • Spectrum and severity of corneal toxicities associated with datopotamab deruxtecan (14:44)
  • Role of optometrists and ophthalmologists in screening for and management of ocular toxicities (17:55)
  • Other ocular toxicities associated with cancer therapies (24:26)
  • Prevention and management of corneal toxicity (33:58)
  • Preexisting ophthalmic conditions as potential risk factors for development of ocular toxicities with ADCs (43:39)
  • General clinical pearls on the management of ocular toxicities with cancer therapies (48:04)

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