CD19 x CD3 BiTEs for Acute Lymphoblastic Leukemia — An Interview with Dr Bijal Shah (Companion Faculty Lecture)
Research To Practice | Oncology Videos · Dr. Neil Love
March 12, 202648m 59s
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Show Notes
Featuring a slide presentation and related discussion from Dr Bijal Shah, including the following topics:
- Historical approaches to managing acute lymphoblastic leukemia, their limitations and present approaches to treatment (0:00)
- Mechanistic approach underlying blinatumomab; key clinical trial data and their implications (7:29)
- Mechanistic approaches underlying surovatamig and MK-1045; dosing and administration strategies with various bispecific T-cell engagers (23:27)
- Key clinical trial data with surovatamig; implications for practice (32:38)
- Key clinical trial data with MK-1045; implications for practice (39:02)
- Synthesizing and comparing data across subcutaneous blinatumomab, surovatamig and MK-1045 (42:36)