Breast Cancer | Oncology Today with Dr Neil Love: Integrating Antibody-Drug Conjugates into the Management of HR-Positive and Triple-Negative Metastatic Breast Cancer
Research To Practice | Oncology Videos · Dr. Neil Love
August 16, 202454m 3s
Audio is streamed directly from the publisher (traffic.libsyn.com) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
Featuring perspectives from Dr Sara A Hurvitz, including the following topics:
- Case: A woman in her late 40s who received treatment for triple-negative breast cancer develops lung metastases 2 years later (0:00)
- Clinical trials investigating TROP2-targeting antibody-drug conjugates (13:28)
- Identifying and targeting HER2 in HER2 low-expressing disease (21:17)
- Case: A woman in her early 50s who received treatment for Stage I breast cancer later develops multiple lesions similar to the original cancer (29:00)
- Thresholds of HER2 expression and the efficacy of trastuzumab deruxtecan (T-DXd) (34:01)
- Case: A woman in her late 50s receiving T-DXd for HER2-low metastatic breast cancer develops asymptomatic ground glass infiltrates in the lung (39:19)
- Novel ADC strategies under investigation (48:22)