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B7-H3-Targeted Antibody-Drug Conjugates | Oncology Today with Dr Neil Love: The Emerging Role of B7-H3-Targeted Antibody-Drug Conjugates

B7-H3-Targeted Antibody-Drug Conjugates | Oncology Today with Dr Neil Love: The Emerging Role of B7-H3-Targeted Antibody-Drug Conjugates

Research To Practice | Oncology Videos · Dr. Neil Love

April 4, 20241h 14m

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Show Notes

Featuring perspectives from Dr Manish Patel, including the following topics:

  • Insights into a comprehensive clinical research practice (0:00)
  • Transformation of the conduct and design of clinical trials (3:41)
  • Disparities and conundrums in clinical trial recruitment (10:11)
  • Rationale of clinical trial dosing and regulatory initiatives (15:37)
  • Innovation and advancements in oncology research and clinical development (18:47)
  • Practical considerations into patient care during a clinical trial (20:52)
  • Encouraging physicians to participate in oncology research (24:29)
  • Pharmacology of B7-H3 and role in tumor pathogenesis (31:56)
  • Current and future clinical development of ifinatamab deruxtecan (I-DXd) (34:11)
  • Available clinical data with vobramitamab duocarmazine across numerous solid tumors (1:02:44)
  • Early clinical data with HS-20093 for advanced solid tumors (1:06:36)

CME information and select publications