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Acute Myeloid Leukemia — An Interview with Dr Eunice S Wang to Review Key Presentations from ASCO and EHA

Acute Myeloid Leukemia — An Interview with Dr Eunice S Wang to Review Key Presentations from ASCO and EHA

Research To Practice | Oncology Videos · Dr. Neil Love

October 23, 202554m 59s

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Show Notes

Featuring an interview with Dr Eunice S Wang, including the following topics:

  • Hypomethylating agent/venetoclax combinations for the treatment of acute myeloid leukemia (AML); integration in community practice (0:00)
  • All-oral regimen of decitabine/cedazuridine with venetoclax for patients with newly diagnosed AML not eligible for intensive induction chemotherapy (9:39)
  • Efficacy of targeted therapy options for AML; potential role of MRD (minimal residual disease) assays in monitoring treatment response (13:07)
  • Treatment approach for patients with FLT3-mutant AML; mutation profiles and predicting response to quizartinib (20:14)
  • Targeting the differentiation of AML tumor cells with IDH and menin inhibitors; associated differentiation syndrome (29:24)
  • Efficacy and tolerability of the IDH inhibitors ivosidenib and olutasidenib (36:54)
  • Key clinical data with approved and investigational menin inhibitors for AML; current and potential integration of menin inhibitors in the AML treatment algorithm (42:30)

CME information and select publications