![PubReading [178] - Mass spectrometry techniques for imaging and detection of metallodrugs - S. Theiner, G. Koellensperger et al.](https://media.rss.com/pub-reading/20220604_120651_b1eb6c62ae4201ef92e04bdcecbaf143.jpg)
PubReading [178] - Mass spectrometry techniques for imaging and detection of metallodrugs - S. Theiner, G. Koellensperger et al.
PubReading · Mando Mourad
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Show Notes
Undoubtedly, metallomic approaches based on mass spectrometry have evolved into essential tools supporting the drug development of novel metal-based anticancer drugs. This article will comment on the state-of-the-art instrumentation and highlight some of the recent analytical advances beyond routine, especially focusing on the latest developments in inductively coupled plasma-mass spectrometry (ICP-MS). Mass spectrometry-based bioimaging and single-cell methods will be presented, paving the way to exciting investigations of metal-based anticancer drugs in heterogeneous and structurally, as well as functionally complex solid tumor tissues.
doi.org/10.1016/j.cbpa.2020.12.005 - 2021