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Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep

Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep

Psychopharmacology and Psychiatry Updates · Psychopharmacology Institute

November 7, 202511m 12s

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Show Notes

In this episode, we explore a head-to-head comparison of trazodone, doxepin, and melatonin for treating insomnia when benzodiazepines are off the table. Which non-benzodiazepine sleep aid offers the best balance of effectiveness and tolerability in real-world psychiatric patients?

Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D.