Melatonin: Is a “Natural” Sleep Aid as Harmless as We Think? - Frankly Speaking Ep 476
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Show Notes
Credits: 0.25 AMA PRA Category 1 Credit™
CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-476
Overview: Melatonin is widely used and often perceived as a safe, natural solution for insomnia. However, a new preliminary study raises concerns about long-term melatonin use and increased risk of heart failure, hospitalization, and all-cause mortality in patients with chronic insomnia. In this episode, we review the findings, discuss how they fit with existing evidence, explore limitations, and offer practical guidance for clinicians counseling patients about sleep supplements.
Episode resource links:
- American Heart Association Scientific Sessions 2025 – Abstract 4371606
AHA Scientific Statement: Multidimensional Sleep Health and Cardiometabolic Risk (Circulation, 2025) - Li et al. Lancet Diabetes & Endocrinology, 2024
- American Academy of Sleep Medicine Clinical Practice Guidelines
- AHA Life’s Essential 8 & Sleep Health Resources
Guest: Mariyan Montaque, DNP, FNP-BC
Music Credit: Matthew Bugos
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The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.