186. Ako urobiť geneticky upravené baktérie bezpečnými?
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Show Notes
Dnes Miro rozpráva o biobezpečnosti a spôsoboch, akými bioinžinieri geneticky upravené bunky robia bezpečnými.----more----
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Referencie
[1] Lee, J. W., Chan, C. T. Y., Slomovic, S., & Collins, J. J. (2018). Next-generation biocontainment systems for engineered organisms. Nature Chemical Biology, 14(6), 530–537. https://doi.org/10.1038/s41589-018-0056-x
[2] Brenner, K., You, L., & Arnold, F. H. (2008, September). Engineering microbial consortia: a new frontier in synthetic biology. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2008.05.004
[3] McCardell, R. D., Pandey, A., & Murray, R. M. (2019). Control of density and composition in an engineered two-member bacterial community. BioRxiv, 632174. https://doi.org/10.1101/632174
[4] D’souza, G., & Kost, C. (2016). Experimental Evolution of Metabolic Dependency in Bacteria. PLoS Genet, 12(11), 1006364. https://doi.org/10.1371/journal.pgen.1006364
[5] Kunjapur, A. M., Napolitano, M. G., Hysolli, E., Appleton, E. M., Schubert, M. G., Jones, M. A., … Church, G. M. (2020). Synthetic auxotrophy remains stable after continuous evolution and in co-culture with mammalian cells. BioRxiv, 2020.09.27.315804. https://doi.org/10.1101/2020.09.27.315804
[6] Pinheiro, F., Warsi, O., Andersson, D. I., & Lässig, M. (2020, July 2). Predicting trajectories and mechanisms of antibiotic resistance evolution. ArXiv. arXiv. https://doi.org/10.1101/2020.07.02.184622
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