Practical Neurology Podcast

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the December 2023 issue of the journal - https://pn.bmj.com/content/23/6/461 Please subscribe to the Practical Neurology podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3vVPClm) or Spotify (https://spoti.fi/4baxjsQ). We'd love to hear your feedback on social media - @PracticalNeurol. The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Prof. Martin Turner (1) hosts Dr. Ruth Wood (2) and Dr. Xin You Tai (3), as they puzzle through two Case Reports from the latest issue of the Practical Neurology journal. The first case (1:11) is one of a 27-yo man, whose initial presentation suggests a form of multiple sclerosis, but turns out to be something more rare - (https://pn.bmj.com/content/23/5/414). The second case (19:16) is that of a 59-yo woman, with a two month history of progressive confusion and gait difficulty against a background of schizophrenia - (https://pn.bmj.com/content/23/5/453). Additional reading: Practical approach to the diagnosis of adult-onset leukodystrophies: an updated guide in the genomic era - https://jnnp.bmj.com/content/90/5/543 (1) Professor of Clinical Neurology and Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, and Consultant Neurologist at John Radcliffe Hospital. (2) Neurology Registrar, University Hospitals Sussex. (3) Clinical Academic Fellow, Nuffield Department of Clinical Neurosciences, Oxford University, and Neurology Specialty registrar, Oxford University Hospital. Please subscribe to the Practical Neurology podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3vVPClm) or Spotify (https://spoti.fi/4baxjsQ). We'd love to hear your feedback on social media - @PracticalNeurol. The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell (1) is joined by Dr. Desmond Kidd (2) to discuss the paper “Neurological involvement by Behçet’s syndrome: clinical features, diagnosis, treatment and outcome”. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/5/386) and the October print issue of the journal. The paper is also discussed by the Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://pnbmj.podbean.com/e/editors-highlights-of-the-october-2023-issue/ (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Behçet's Syndrome Centre of Excellence, The Royal London Hospital, London, UK (https://www.behcets.nhs.uk) Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the October 2023 issue of the journal (https://pn.bmj.com/content/23/5/365). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

In the third episode of this new series of the Practical Neurology podcast, Prof. Martin Turner (1) hosts Dr. Ruth Wood (2) and Dr. Xin You Tai (3) in a discussion of two Case Reports from the latest issue of the Practical Neurology journal. The first case (0:36) is one of a 78-yo man with variable slurring speech and swallowing difficulties - "Bilateral hypertrophic olivary degeneration in symptomatic palatal tremor" (https://pn.bmj.com/content/23/4/346). The second case (19:21) is a first-person report from the "Me and My Neurological Illness" section, with a 56-yo man living with Parkinson's getting into difficulty while swimming in open water - "Near-drowning in Parkinson’s disease: common or uncommon?" (https://pn.bmj.com/content/23/4/354). (1) Professor of Clinical Neurology and Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, and Consultant Neurologist at John Radcliffe Hospital. (2) Neurology Registrar, University Hospitals Sussex. (3) Clinical Academic Fellow, Nuffield Department of Clinical Neurosciences, Oxford University, and Neurology Specialty registrar, Oxford University Hospital. Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). We'd love to hear your feedback on social media - @PracticalNeurol. The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell (1) is joined by the authors of the paper “First-line immunosuppression in neuromuscular diseases”, Dr Michael Foster, Prof Michael Lunn, Dr Aisling Carr (2). Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/4/327) and the August print issue of the journal. The paper is also discussed by the Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://pnbmj.podbean.com/e/editors-highlights-of-the-august-2023-issue/ (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, London, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the August 2023 issue of the journal (https://pn.bmj.com/content/23/4/269). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

In the second episode of this new series of the Practical Neurology podcast, Prof. Martin Turner (1) hosts Dr. Ruth Wood (2) and Dr. Xin You Tai (3) as they delve into two Case Reports from the latest issue of the Practical Neurology journal. First up this month (0:42) is a young man, presumed suffering from a drug overdose, with symptoms of transient global amnesia. This case is determined to be an example of "Cerebellar Hippocampal and Basal Nuclei Transient Edema with Restricted diffusion (CHANTER) Syndrome" (https://pn.bmj.com/content/early/2023/04/17/pn-2023-003724). Next (13:07) is a young woman with urinary retention and leg paraesthesia over multiple days. Investigations showed this to be "Conus medullaris syndrome as a presenting feature of MOG-associated disease" (https://pn.bmj.com/content/early/2023/01/13/pn-2022-003560). (1) Professor of Clinical Neurology and Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, and Consultant Neurologist at John Radcliffe Hospital. (2) Neurology Registrar, University Hospitals Sussex. (3) Clinical Academic Fellow, Nuffield Department of Clinical Neurosciences, Oxford University, and Neurology Specialty registrar, Oxford University Hospital. Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell (1) is joined by the authors of "Multiple system atrophy", a review recently published in Practical Neurology. The guests, Dr. Yee Yen Goh (2), and Dr. Viorica Chelban (2), detail the effects of this condition, describe its detection, and provide information on the support that patients can receive. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/3/208) and the June print issue of the journal. The paper is also discussed by the Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://pnbmj.podbean.com/e/editors-highlights-of-the-june-2023-issue/ (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) UCL Queen Square Institute of Neurology, London, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the June 2023 issue of the journal (https://pn.bmj.com/content/23/3). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

In this new series of the Practical Neurology podcast, Professor Martin Turner (1) invites Dr Ruth Wood (2) and Dr Xin You Tai (3) to discuss the nitty-gritty details of two Case Reports from the latest issue of the Practical Neurology journal. This month, they start by commenting on a case of a woman in her 70s with renal failure who developed confusion and seizures after receiving aciclovir, and was subsequently diagnosed with aciclovir-induced neurotoxicity (Aciclovir-induced neurotoxicity - https://pn.bmj.com/content/23/2/157). They also talk (starting at 23:05) about an unusual case of an acute posterior spinal artery syndrome in a man in his 60s with vascular risk factors (Posterior spinal artery infarct - https://pn.bmj.com/content/23/2/160). (1) Professor of Clinical Neurology and Neuroscience at the Nuffield Department of Clinical Neurosciences, University of Oxford, and Consultant Neurologist at John Radcliffe Hospital. (2) Neurology Registrar, University Hospitals Sussex. (3) Clinical Academic Fellow, Nuffield Department of Clinical Neurosciences, Oxford University, and Neurology Specialty registrar, Oxford University Hospital. Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1) is joined by a selection of the authors of "Toxic neuropathies; a practical approach", a review recently published in Practical Neurology. The guests, Dr. Duncan Smyth(2), Dr. Aisling Carr(3) and Prof. Michael Lunn(3), explain the background to these conditions and describe approaches to treatment and care of toxic neuropathy patients. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/2/120) and the April print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-april-2023-issue?in=bmjpodcasts/sets/pn-podcast (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Dept. of Neurology, Wellington Hospital, Wellington, NZ (3) MRC Centre for Neuromuscular Diseases, National Hospital for Neurology, University College London Hospitals, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the April 2023 issue of the journal (https://pn.bmj.com/content/23/2/103). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1) discusses a recently published review by Dr. Christopher Carswell(2) on the historical context of normal pressure hydrocephalus, the challenges faced when dealing with patients, and the current state of clinical evidence for diagnosis and treatment. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/23/1/15) and the February print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-february-2023-issue?in=bmjpodcasts/sets/pn-podcast (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Imperial College Healthcare NHS Trust, London, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the February 2023 issue of the journal (https://pn.bmj.com/content/23/1/1). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1) discusses a recently published review by Dr. Jeremy Rees(2) and Dr. Michael Kosmin(3) on the subject of radiation therapy on the brain, the history and motivation of its use, and its benefits and limitations. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/6/450) and the December print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-december-2022-issue?in=bmjpodcasts/sets/pn-podcast (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Neurology, National Hospital for Neurology and Neurosurgery, London, UK (3) Clinical Oncology, University College London Hospitals NHS Foundation Trust, London, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the December 2022 issue of the journal (https://pn.bmj.com/content/22/6/445). Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1), interviews Dr. Jon Walters(2) about his recent review of approaches to weakness in the Intensive Care Unit (ICU). Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/5/358) and the October print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-october-2022-issue?in=bmjpodcasts/sets/pn-podcast (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Consultant Neurologist, Morriston Hospital, Swansea, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the October 2022 issue of the journal. Read the highlights: https://pn.bmj.com/content/22/5/341. Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1), interviews Dr. Stephen Kirker(2) about his recent paper detailing the use of appropriate orthoses for patients with weakness or abnormal posture of their lower leg, and they discuss the sorts of problems that can be helped in neurological practice and the range of devices commonly used. Read the latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/4/311) and the August print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-august-2022-issue (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Rehab Medicine Department, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The Practical Neurology podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the August 2022 issue of the journal. Read more on the PN website: https://pn.bmj.com/content/22/4/261 The full issue here: https://pn.bmj.com/content/22/4 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Dr. Amy Ross Russell(1), interviews Assoc. Prof. Todd Hardy(2) and Dr. James Triplett(3), about their recent paper detailing the clinical approach to diagnosis and management of Posterior Reversible Encephalopathy Syndrome (PRES). Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/3/183) and the June print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr. Phil Smith and Dr. Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-june-2022-issue?in=bmjpodcasts/sets/pn-podcast (1) Neurology, University Hospital Southampton NHS Foundation Trust, UK (2) Staff Specialist Neurologist at Concord Hospital, Clinical Associate Professor in Medicine at the University of Sydney, Australia (3) Staff Specialist Neurologist and Neurophysiologist, Concord Hospital, Sydney, Australia Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). The PN podcast is produced by Letícia Amorim and edited by Brian O'Toole. Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the June 2022 issue of the journal. Read more on the PN website: https://pn.bmj.com/content/22/3/175 The full issue here: https://pn.bmj.com/content/22/3 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Dr Amy Ross Russell, Neurology, University Hospital Southampton NHS Foundation Trust, interviews Dr William Diprose, Dept. of Neurology, Auckland City Hospital and Dept. of Medicine, Faculty of Medicine and Health Science, University of Auckland, New Zealand; Dr Anthony Jordan, Dept. of Clinical Immunology and Allergy, Auckland City Hospital, NZ; and Dr Neil Anderson, Dept. of Neurology, Auckland City Hospital, NZ about their recent paper reviewing the neurological features of specific autoinflammatory syndromes. Read this latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/2/145) and the April print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr Phil Smith and Dr Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/pn-april-2022-highlights?in=bmjpodcasts/sets/pn-podcast Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the April 2022 issue of the journal. Read more on the PN website: https://pn.bmj.com/content/22/2/93 The full issue here: https://pn.bmj.com/content/22/2 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Dr Amy Ross Russell, Neurology, University Hospital Southampton NHS Foundation Trust, interviews Dr Sophie Binks and Professor Sarosh Irani, from the Oxford Autoimmune Neurology Group, about their recent paper about a practical approach to diagnosis and management of paraneoplastic neurological syndromes. Read the latest Editor’s Choice paper on the Practical Neurology website (https://pn.bmj.com/content/22/1/19) and the February print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr Phil Smith and Dr Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-february-2022-issue?in=bmjpodcasts/sets/pn-podcast Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the February 2022 issue of the journal. Read more on the PN website: https://pn.bmj.com/content/22/1/1 The full issue here: https://pn.bmj.com/content/22/1 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Dr Amy Ross Russell, Neurology, University Hospital Southampton NHS Foundation Trust, interviews Dr Fahmida Chowdhury and Dr Matthew Walker, both from the National Hospital for Neurology and Neurosurgery, London, about their recent paper, summarising the current literature on localisation in focal epilepsies using illustrative cases and discussing possible pitfalls in localisation. Read the paper on the Practical Neurology website (https://pn.bmj.com/content/21/6/481) and the December print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr Phil Smith and Dr Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-december-2021-issue?in=bmjpodcasts/sets/pn-podcast Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the October issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/6/463. The full issue here: https://pn.bmj.com/content/21/6 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Autoimmune encephalitis comprises a group of disorders in which the host immune system targets self-antigens expressed in the central nervous system (CNS). Some of the best-characterised diseases are associated with autoantibodies that target neuroglial antigens. These autoantibodies are considered pathogenic because they are directed against the extracellular—and hence in vivo exposed—domains of their target antigens. Associate Editor of Practical Neurology, Dr Tom Hughes, Department of Neurology, Cardiff, interviews Prof Sarosh R Irani, Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, Oxford University, about his recent paper, in which he summarised the well-known autoantibody-mediated encephalitis syndromes with neuronal cell-surface antigens and focus on practical aspects of their diagnosis and treatment, offer their clinical experiences of managing such cases and highlight more basic neuroimmunological advances that will inform their future diagnosis and treatments. Read the paper on the Practical Neurology website (https://pn.bmj.com/content/21/5/412) and the October print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr Phil Smith and Dr Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-october-2021-issue?in=bmjpodcasts/sets/pn-podcast Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the October issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/5/373 The full issue here: https://pn.bmj.com/content/21/5 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

As the number of people with dementia worldwide approaches 50 million, the need for early and accurate diagnosis is more urgent than ever. However, the biggest challenge is often suspecting dementia in the first place and deciding why this is not ‘just’ Alzheimer’s disease. Associate Editor of Practical Neurology, Dr Tom Hughes, Department of Neurology, Cardiff, interviews Dr Jeremy Johnson and Dr Jason Warren, both from the Dementia Research Centre, UCL Queen Square Institute of Neurology, London, about their recent paper, in which they outline a practical, symptom-led, bedside approach to suspecting dementia and its likely diagnosis, inspired by clinical experience and based on recognition of characteristic syndromic patterns. You can read the paper on the Practical Neurology website (https://pn.bmj.com/content/21/4/300) and the August print issue of the journal. The paper is also discussed by Practical Neurology editors, Dr Phil Smith and Dr Geraint Fuller, in their latest podcast: https://soundcloud.com/bmjpodcasts/editors-highlights-of-the-august-2021-issue?in=bmjpodcasts/sets/pn-podcast Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the August issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/4/273 The full issue here: https://pn.bmj.com/content/21/4 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the June issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/3/183 The full issue here: https://pn.bmj.com/content/21/3 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the April issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/2/91 The full issue here: https://pn.bmj.com/content/21/2 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the February issue of the journal. Read more on the PN website: https://pn.bmj.com/content/21/1/1 The full issue here: https://pn.bmj.com/content/21/1

Dr Tom Hughes, Department of Neurology, Cardiff, interviews Dr Luis Idrovo, Department of Neurology, Leeds, about one of the most prevalent, disabling and undertreated conditions in neurological clinical practice: headaches. They discuss the administration of peripheral nerve blocks to treat various headache disorders both in the acute and outpatient setting. Please read the related paper, which is the Editor's Choice of the February 2021 issue of the journal: https://pn.bmj.com/content/21/1/30 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the December issue of the journal. Read more on the PN website: https://pn.bmj.com/content/20/6/427 The full issue here: https://pn.bmj.com/content/20/6

In the return of the Practical Neurology Podcast, Dr Tom Hughes interviews Dr Saúl Reyes, Consultant Neurologist at the Blizard Institute, and The London School of Medicine and Dentistry, Queen Mary University of London, UK. They discuss the important issues regarding what vaccinations people with MS should have, and when they should have them in relation to their immunosuppressant drugs. Read the accompanying paper on the Practical Neurology's November issue and online at http://dx.doi.org/10.1136/practneurol-2020-002527 Please subscribe via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Essential tremor is the most common form of tremor in humans. In this podcast, Dr Tom Hughes, Practical Neurology Associate Editor, interviews Dr Elan D Louis, Yale Neurology, Division of Movement Disorders, New Haven, CT, who’s the author of a recent paper called, ‘Essential tremor: a nuanced approach to the clinical features’. They discuss this condition, not always easy to diagnose, and the distinction between essential tremor and Parkinson’s disease as well as dystonia. Read the paper on the Practical Neurology website: https://pn.bmj.com/content/19/5/389.

‘Query encephalitis’ is a common neurological consultation in hospitalised patients. Identifying the syndrome is only part of the puzzle. Although historically encephalitis has been almost synonymous with infection, we increasingly recognise parainfectious or postinfectious as well as other immune-mediated causes. Encephalitis must also be distinguished from other causes of encephalopathy, including systemic infection, metabolic derangements, toxins, inherited metabolic disorders, hypoxia, trauma and vasculopathies. The paper discussed in this podcast reviews the most important differential diagnoses (mimics) of patients presenting with an encephalitic syndrome and highlight some unusual presentations (chameleons) of infectious encephalitis. Listen to the conversation of Dr Tom Hughes, Practical Neurology Associate Editor, with Dr Nicholas Davies (Department of Neurology, Chelsea and Westminster Hospital, London, UK) and read the paper on the Practical Neurology website: http://dx.doi.org/10.1136/practneurol-2018-002114.

A framework to guide general neurologists in the diagnostic reassessment of people with epilepsy and complex neurological problems of unknown cause is discussed in this podcast. Dr Tom Hughes, Practical Neurology Associate Editor, is joined by Dr Lina Nashef (King’s College Hospital, London, UK), the corresponding author of the paper “Investigating adults with early-onset epilepsy and intellectual or physical disability”, which also addresses imaging, electroencephalography, genetic studies and metabolic testing. Read the paper included on the Practical Neurology April issue here: ttps://pn.bmj.com/content/19/2/115.

The basic principles of B-cell depletion with therapeutic monoclonal antibodies, the available evidence for using rituximab in neurological diseases as well as prescribing advice are discussed in this podcast. Practical Neurology Associate Editor Dr Tom Hughes is joined by Dr Daniel Whittam and Dr Anu Jacob, the authors of the review paper: “Rituximab in neurological disease: principles, evidence and practice”, which is part of the Practical Neurology February issue (https://pn.bmj.com/content/19/1/5).

What do adult neurologists need to know ahead of the likely licensing of Epidiolex for epilepsy in the UK in 2019? It is quite possible that cannabidiol, currently licensed in the USA for treating rare genetic epilepsies, may open the door for the widespread legalisation of recreational cannabis. Dr Rhys Thomas (Neurologist at the Institute of Neuroscience, Newcastle University, UK) tells fellow Practical Neurology Associate Editor Dr Tom Hughes why the arguments about who may benefit from cannabis-derived medicines have to be separate from the discussion about the legalisation of recreational cannabis. They also discuss the distinction between cannabidiol oils and the cannabidiol rigorously tested in clinical trials. Read the review on the Practical Neurology website - https://pn.bmj.com/content/early/2018/10/18/practneurol-2018-002058 - and on the journal's December 2018 issue.

Valproate is now contraindicated in pregnancy and women of child-bearing potential. The new stipulations from the Coordination Group for Mutual Recognition and Decentralised Procedures-Human (CMDh), a regulatory body representing European Union member states, about the use of valproate in women of child-bearing potential states that “Valproate should never be started unless alternative treatments are not suitable”. However, people taking this drug used to treat epilepsy should not stop valproate use abruptly, without consulting their doctor. The new regulations are discussed in this podcast by Professor Sanjay Sisodiya (UCL Institute of Neurology, London), who’s the author of a Practical Neurology editorial on this subject (http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001955). Other related articles in the Practical Neurology website: ►http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001932 ► http://pn.bmj.com/content/early/2018/04/19/practneurol-2018-001931

Professor Michael Hanna, Senior Consultant Neurologist at Queen Square, UCL, London, discusses the developments in genetics in neuromuscular diseases with Eric Hoffman, Gordon Holmes lecturer at the ABN meeting 2017, in Liverpool. Professor Eric Hoffman (Binghampton University, USA) describes in this conversation his extensive work on the rare condition of Duchenne’s muscular dystrophy. This is the last of a series of podcasts recorded at the 2017 ABN meeting, held in May, in Liverpool, UK. More on this subject on the Practical Neurology website: http://pn.bmj.com/, where you can find these particular articles as well: "Muscle disease" - http://pn.bmj.com/content/9/1/54; "Muscle diseases: mimics and chameleons" - http://pn.bmj.com/content/14/5/288.

Nodding syndrome affects children from 5 to 15 years old in some parts of the African continent. In this podcast, David Nicholl, Department of Neurology, City Hospital, Birmingham, UK, is joined by Mark Ellul, ABN fellow, University of Liverpool, UK, to discuss the latest research in this epileptic disorder. They talked at the Association of British Neurologists annual meeting, Liverpool, May 2017. http://pn.bmj.com/

Professor Andrew Schwartz (University of Pittsburgh, USA) discusses the latest progress toward high-performance neural prosthetics with Practical Neurology's editor Geraint Fuller. The subject was highlighted at the ABN annual meeting 2017, held in May, in Liverpool, UK. For more content on this topic please visit http://pn.bmj.com/.

At the ABN annual meeting 2017, David Burn interviews Kevin Talbot on the his talk on Antisense treatments in spinal muscular atrophy. The ABN Autumn Meeting took place on Wednesday 3rd May in Liverpool. For more content on this topic please visit: pn.bmj.com/

Based on the ABN's Autumn Meeting, Martin Turner interviews Matthew Wood on the his lecture Antisense treatments in neurological disease. The ABN Autumn Meeting took place on 20th October 2016 in London. For more content on this topic please visit: pn.bmj.com/