Kary Mullis: The LSD-Taking Nobel Laureate Who Revolutionized DNA (And Talked to Raccoons)
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Show Notes
In this episode of pplpod, we dive into the wild life of Kary Mullis, the eccentric American biochemist whose invention of the polymerase chain reaction (PCR) revolutionized genetics, medicine, and forensics. We explore how a surfer, musician, and former bakery manager came up with a world-changing idea while driving a Honda Civic through Mendocino County—an invention that would win him the 1993 Nobel Prize in Chemistry.
Join us as we discuss:
• The Breakthrough: How Mullis developed PCR at Cetus Corporation, dividing biology into "before" and "after" epochs, despite his erratic behavior and clashes with colleagues.
• The Counterculture Scientist: Mullis's openness about his use of hallucinogens, including his claim that LSD was more important to his experience than his university courses and may have helped him visualize PCR.
• The "Nobel Disease": The controversial later years where Mullis used his platform to deny the link between HIV and AIDS, reject climate change consensus, and profess belief in astrology.
• The Paranormal: His bizarre account of encountering a "glowing," talking raccoon he suspected was an extraterrestrial.
From selling jewelry containing the DNA of dead celebrities to his death in 2019, we examine the complex legacy of a scientific genius who walked the fine line between brilliance and pseudoscience.