Audio is streamed directly from the publisher (media.transistor.fm) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们关注发表在Journal of ethnopharmacology(影响因子4.8)上的重要研究："Integrative elucidation of Panax notoginseng's action against pulmonary hypertension: Network pharmacology and molecular docking insights."这项研究揭示了传统中药三七对抗肺动脉高压的机制。研究发现三七的活性成分与AKT1、TNF和IL6等核心靶点有很强的结合亲和力，并通过Notch3、MAPK、SIRT1/FOXO3a/p27和NLRP3/Caspase-1/GSDMD等多种信号通路发挥作用。这一发现为三七在心血管疾病管理中的应用提供了科学依据，特别是在预防和治疗肺动脉高压方面展现了广阔前景，为未来药物开发奠定了理论基础。
Topics
bioinformatics