Plenary Session - inactive due to federal service

On today's episode, we interview Dr. Jeffrey Flier, an esteemed endocrinologist and physician researcher who was Dean of the Faculty of Medicine at Harvard University for nine years (2007-2016). We talk about his career in academic medicine as well as the challenges of 2021. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we bring back popular guest Dr. David Russler-Germain, a Hematology/Oncology Fellow at the Washington University School of Medicine in St. Louis, to discuss his thoughts on PhD programs (in response to a listener question) as well as his take on Idecabtagene vicleucel for multiple myeloma. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we talk with Dr. Martin Kulldorff, a Professor of Medicine at Harvard Medical School and Brigham and Women's Hospital, about COVID-19 health policy and about disagreement. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we bring back popular guest Dr. Adam Cifu, a Professor of Medicine at the University of Chicago, to talk about the idea of banning books. the power of social media, and the current state of medical education. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we are joined by Samantha Godwin, a Resident Fellow for the Information Society Project at Yale Law School, to discuss COVID-19 health policy from a legal and philosophical perspective. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we talk again with Dr. David Russler-Germain, a Hematology/Oncology Fellow at the Washington University School of Medicine in St. Louis, this time on the Medical Scientist Training Program (MSTP). Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Tom Beer, the Deputy Director of the Oregon Health & Science University Knight Cancer Institute, about COVID-19 transmission, policy, and vaccines. We also talk about olaparib. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we are joined by guest Dr. Carl Hart, a behavioral neuroscientist and Professor of Psychology at Columbia University. We discuss his research, his philosophies, and his new book "Drug Use for Grown-Ups." Drug Use for Grown-Ups: https://www.penguinrandomhouse.com/books/534657/drug-use-for-grown-ups-by-dr-carl-l-hart/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we bring back popular guest Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology at University of Michigan Medicine, to discuss treatment of Acute Lymphoblastic Leukemia (ALL). Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we are joined by genomicist Dr. Nathan Pearson, founder of Root (rootdeep.com), to discuss which genetic alterations in the host predispose to SARS-CoV-2 acquisition and bad outcomes. Gift of Life: www.giftoflife.org/page/content/covid19faq Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we bring back popular guest Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School, for a discussion on expertise, disinformation, and intellectual disagreement. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we talk with popular guest Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada about mapping out a career path after medical school and about his new paper out now in JAMA Oncology titled "Evolution of the Randomized Clinical Trial in the Era of Precision Oncology". The Oncology RCT: doi.org/10.1001/jamaoncol.2021.0379 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Ghulam Rehman Mohyuddin of Kansas University Medical Center on his new paper out now in The Lancet Haematology titled "Quality of control groups in randomised trials of multiple myeloma enrolling in the USA: a systematic review". Control Groups: doi.org/10.1016/S2352-3026(21)00024-7 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, to discuss the morality and philosophical backbone behind COVID-19 vaccine distribution and how we should define equity; cancel culture and its historical longevity; and the impossibility (at least in the USA) of Zero COVID-19. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

For today's episode we have a short monologue in remembrance of famed cancer researcher Dr. José Baselga. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Aaron Richterman, an infectious disease specialist at Penn Medicine. We talk about updates on all things COVID-19 and we look back at how treatments, risk assessment, and behavior have changed. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Bob Wachter, the Chair of the Department of Medicine at University of California San Francisco. We talk about a wide range of topics including medicine, leadership, SARS-CoV-2, and social media. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we interview Youyang Gu, an independent data scientist who created some of the most models of the COVID-19 pandemic. He talks us through how he made the projections. His work is available on his website: https://covid19-projections.com/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's SHORT episode, we talk about censorship, Facebook, Twitter, and the "evildoer" Dr. Marty Makary. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Robert Freudenthal, a psychiatrist in training at Barnet Enfield and Haringey Mental Health Trust in London, UK. We talk abut the power of the state and its role in public health policy. We focus specifically on how governments worldwide have responded to the COVID-19 pandemic, from extreme lockdowns to harm reduction advisories. We discuss how policy can be medical overreach as well as how it interplays with the criminal justice system and racial and class inequities. Finally, we discuss censorship and the need for trust and honesty in messaging. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Luc Morris of Memorial Sloan Kettering Cancer Center on his new paper out now in JAMA Oncology titled "Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Solid Tumors With 10 or More Mutations per Megabase". Response Rates: doi.org/10.1001/jamaoncol.2020.7684 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of the HIV Clinic at SFGH, on COVID-19 interventions. We talk about results from the vaccine studies and how vaccination is perceived by the public. We talk about her new paper out now in The Lancet Infectious Disease on the importance of non-pharmaceutical interventions (masking, social distancing, ventilation, hand-washing) in controlling COVID-19. We also talk about the stark difference between messaging created from the point of view of an epidemiologist vs the public health messaging that frontline health care workers deliver directly to patients. We end the interview by talking about schools and the need to re-open them. Importance of non-pharmaceutical interventions: doi.org/10.1016/S1473-3099(20)30982-8 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Dr. Tracy Høeg on her new paper and her ongoing research into COVID-19 transmission in K-12 schools in Wisconsin, USA. Dr. Høeg is an epidemiologist and an interventional sports and medicine spine specialist at Northern California Orthopaedic Associates. Her paper is titled "COVID-19 Cases and Transmission in 17 K-12 Schools - Wood County, Wisconsin, August 31-November 29, 2020" and is published in the CDC's Morbidity and Mortality Weekly Report. Cases in K-12 Schools: doi.org/10.15585/mmwr.mm7004e3 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we interview Dr. Bryan Carmody, commonly known as the Sheriff of Sodium. He's a pediatric nephrologist at Children's Hospital of the King's Daughters in Virginia. We talk with him about the USMLE Steps (Step 1, Step 2, and Step 2 CS), their usefulness, their origins, and how to reform them. We also break down and discuss the inner workings of residency matching and the M.D. and D.O. designations. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we sit down with Dr. Alex John London, the Clara L. West Professor of Ethics and Philosophy and Director of the Center for Ethics and Policy at Carnegie Mellon University, to discuss the role of philosophy, COVID-19 exceptionalism, and various aspects of COVID-19 health policy including masking, vaccination, and schools. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today’s episode we review the findings of the Beat AML study as published in Nature Medicine in an article titled “Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial”. Beat AML: doi.org/10.1038/s41591-020-1089-8 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

For today's episode, we sit down with Drs. Ade Adamson of the University of Texas at Austin Dell Medical School and Ben Mazer of Johns Hopkins Hospital to discuss their new paper out now in the New England Journal of Medicine titled "The Rapid Rise in Cutaneous Melanoma Diagnoses". It's one of the best papers you'll read all year. Melanoma Diagnoses: doi.org/10.1056/NEJMsb2019760 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

For today's special episode, we sat down with Dr. John Ioannidis of Stanford University for an outdoor in-person interview. We take a deep dive into his work from 2000 all the way up to present day: his career from 2000 to 2010, his move to Stanford, and his work on COVID-19. We take a deep dive into his work on COVID-19: IFR, shielding ratio, the question of whether lockdown works, opening schools, and what public health policy should be. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we're joined by geneticist Dr. Francois Balloux, the Director of the University College London Genetics Institute and professor of computational systems biology, on pandemic mitigation, SARS-CoV-2 variants, how news and social media amplify fear over fact, opening schools, lethality and risk, the origin of SARS-CoV-2, COVID-19 vaccine efficacy and vaccine escape, and more! Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we feature an in-depth interview with Dr. Julia Marcus (Associate Professor at Harvard Medical School) and Dr. Stefan Baral (Associate Professor at Johns Hopkins Bloomberg School of Public Health), two infectious disease epidemiologists, on public health messaging around COVID-19 -- what we're getting right and where we're going terribly wrong. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we sit down with Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada to discuss his new paper out now in JAMA Oncology titled "An Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries". We also talk about how COVID-19 has affected oncology research. We touch, too, on the topic of evaluating how you spend your time and prioritizing your research. Contemporary Oncology RCTs: doi.org/10.1001/jamaoncol.2020.7478 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we are joined by Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School. We discuss his forthcoming book on skepticism, elites, and expertise, as well as his article out now on StatNews about the myth of COVID-19 denial. We talk about anti-intellectualism and how science ought to be debated in the era of trade-offs and COVID-19. Straw Man of Pandemic Denial: www.statnews.com/2020/12/23/put-straw-man-pandemic-denial-out-of-its-misery/comment-page-1/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we sit down with Dr. Arye Elfenbein, a cardiologist and "doctorpreneur " to interview him on the bio-tech company he recently co-founded: Wildtype. Wildtype manufactures ex-vivo fish meat for human consumption in fulfillment of their mission to create the cleanest, most sustainable seafood. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we interview Anne Sosin of Dartmouth College on public health policy in Vermont and how the state has uniquely tamed the COVID-19 pandemic. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, for a far-ranging discussion on COVID-19 from a philosopher's point of view. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we are joined by Dr. Aaron Goodman, an Assistant Clinical Professor at the University of California San Diego, who talks with us about hematologic malignancies, transplantation, and our new paper out now in Blood titled "Persistent Challenges with Treating Multiple Myeloma Early". Persistent Challenges: doi.org/10.1182/blood.2020009752 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we talk with Dr. Stephen Bradley, a General Practitioner and Clinical Research Fellow at the University of Leeds, on publishing in medical journals -- peer review, editorial practices, anti-intellectualism, and more! Notes on Nationalism: www.orwellfoundation.com/the-orwell-foundation/orwell/essays-and-other-works/notes-on-nationalism/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today we have for you an episode of random thoughts. We talk over the ramifications of the strict COVID-19 policy that prevents people from visiting their dying loved ones in the hospital. We also talk more about Norman Wang and his surrounding controversy given the recent lawsuit the Center for Individual Rights has filed against the University of Pittsburgh on his behalf. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on our new paper out now in The Lancet Oncology titled "Considering benefit and risk before routinely recommending SpaceOAR". SpaceOAR: doi.org/10.1016/S1470-2045(20)30639-2 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we discuss censorship in medicine in all its forms with legal expert Jonathan Darrow, an Assistant Professor at Harvard Medical School. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we talk podcasting and the history of medicine with Dr. Adam Rodman, the creator and host of the wildly popular podcast Bedside Rounds, and a hospitalist at the Beth Israel Deaconess Medical Center. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

On today's episode we discuss all the new drugs for acute myeloid leukemia with Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology at University of Michigan Medicine. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Today's episode is an interview with Dr. Saurabh Jha, an Associate Professor of Radiology at the Hospital of the University of Pennsylvania, on the importance of debate and dialogue both historically and in today's modern context. This is the second episode in our experiment in breaking our content up into bite-sized, single-topic episodes. What do you think? Do you prefer a shorter, single-focus episode, or do you prefer our old format? Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Now that we are nine months into the COVID-19 pandemic in the United States, we invite Dr. Alasdair Munro, a pediatrics infectious disease expert, back on to the show to discuss recent developments in public health policy concerning the spread of COVID-19, the risk of it, and children. We also talk about the rigorously policed echo chamber of Twitter, specifically #medtwitter, and finding an audience for controversial opinions. This week is also the start of an experiment in breaking our content up into bite-sized, single-topic episodes. What do you think? Do you prefer a shorter, single-focus episode, or do you prefer our old format? Evidence summary of pediatric COVID-19: https://dontforgetthebubbles.com/evidence-summary-paediatric-covid-19-literature/ Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

This week we return to our roots of oncology and dissect the recent results from KEYNOTE-177. We also have an in-depth interview with mathematician Dr. Wes Pegden of Carnegie Mellon University on a mathematical approach to the COVID-19 pandemic. KEYNOTE-177: doi.org/0.1056/NEJMoa2017699 COVID-19 Mathematical Model: https://math.cmu.edu/~wes/covid.html Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

We have a short and sweet episode for you this week -- no monologue, just two deep-dives with two stellar guests. Our first interview is with Dr. Zubin Damania (known as ZDoggMD) and we cover everything from making original music to the artistry of professional oratory to the pain of electronic health records. Our second interview is a return to our popular segment Journal Club with a Fellow: We invite on Dr. Karine Tawagi of the Oschner Clinic in Louisiana to discuss the JAVELIN 100 study. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Our first guests this week are Drs. Adam Cifu and Scott Stern and are on to discuss their new podcast Symptom to Diagnosis -- based on their book of the same name -- about clinical reasoning. Next we bring back political scientist Dr. Vlad Kogan (from episode 3.13) to discuss the need to re-open schools in the context of rising COVID-19 cases and a changing political landscape. Finally we interview Dr. Carycruz Bueno on her critical research into the harms of fully virtual schooling. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

First up this week we interview constitutional law scholar Leah Litman, an Assistant Professor of Law at the University of Michigan, on Dr. Norman Wang and the intricacies of the laws on affirmative action. Next, we talk with Dr. Patrick DeMartino, a pediatric hematology/oncology fellow at Oregon Health & Science University, on his new paper out now in JAMA Internal Medicine: "Potential Cost Implications for All US Food and Drug Administration Oncology Drug Approvals in 2018". Finally, we sit down with Dr. John Mandrola for an in-depth discussion on the intersection of medicine, politics, and advocacy. Cost Implications: doi.org/10.1001/jamainternmed.2020.5921 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

We have a multitude of interviews for you this week. We start by interviewing Dr. Julia Marcus of the Harvard Medical School and Harvard Pilgrim Health Care Institute on messaging around public health interventions during the COVID-19 pandemic. We continue talking about COVID-19 with Anne Sosin and Dr. Elizabeth Carpenter-Song, both of Dartmouth College. They join us on the podcast to discuss how the Northeast region of the United States has uniquely handled COVID-19. Finally, we bring back the Journal Club with a Fellow segment and interview Dr. David Russler-Germain of Washington University School of Medicine in St. Louis on a new paper out now in The Lancet on CAR T-cell therapy in DLBCL: TRANSCEND NHL 001. TRANSCEND NHL 001: doi.org/10.1016/S0140-6736(20)31366-0 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

We talk this week with Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of the HIV Clinic at SFGH. Speaking from decades of experience treating HIV/AIDS patients, she gives us her take on the public health policies enacted in response to the COVID-19 pandemic. We then conclude this week's episode with a Classical Hematology Chat with Dr. Sven Olson of Oregon Health & Science University. Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew