PLAY PODCASTS
People Behind the Science Podcast Stories from Scientists about Science, Life, Research, and Science Careers

People Behind the Science Podcast Stories from Scientists about Science, Life, Research, and Science Careers

307 episodes — Page 3 of 7

Ep 766766: Cosmic Conquests - Seeking to Answer Key Questions About Our Universe - Dr. Jo Dunkley

Dr. Jo Dunkley is a Professor of Physics and Astrophysical Sciences at Princeton University and author of the book Our Universe: An Astronomer's Guide. Jo is a cosmologist, and her job is to study the universe. She conducts research to try to approximate how space behaves as a whole. This includes looking into space and taking measurements to determine how the universe began, what it's made of, how it's growing, and what is going to happen to it in the future. Physics and family are two of the major pieces in Jo's life. She loves spending time with her two daughters, while they run, draw, sing, and learn about space. She received her MSci with First Class Honors in Natural Sciences from the University of Cambridge and her PhD in Astrophysics from the University of Oxford. Afterwards, she conducted postdoctoral research and was subsequently a Visiting Research Fellow at Princeton University. Before joining the faculty at Princeton University, Jo served on the faculty at the University of Oxford. Over the course of her career, Jo has received numerous awards and honors including the Maxwell Medal from the Institute of Physics, the Royal Astronomical Society's Fowler Prize in Astronomy, the Royal Society Rosalind Franklin Award, the Royal Society Wolfson Merit Award, and the Philip Leverhulme Prize from the Leverhulme Trust. She also shared the Gruber Foundation Cosmology Prize, a NASA Group Achievement Award, and most recently the Breakthrough Prize for Fundamental Physics with the Wilkinson Microwave Anisotropy Probe team. In our interview, Jo speaks about some of her experiences in life and science.

Jun 24, 202431 min

Ep 765765: Applying Systems Biology Approaches to Advance Our Understanding of Infectious Disease - Dr. John Aitchison

Dr. John Aitchison is President and Director of the Center for Infectious Disease Research, the largest independent, non-profit organization in the U.S. that is focused solely on infectious disease research. In addition, John serves as an affiliate or adjunct Professor at the University of Washington, the University of British Columbia, the University of Alberta, and the Institute for Systems Biology. John's research investigates the systems biology related to infectious disease by using technology, computation, and high throughput biology to examine molecules in complex biological systems to better understand how the system will react to a new stimulus or perturbation. Their ultimate goal is to predict how effective a drug or vaccine will be against a particular disease and to implement it with high efficiency. When he's not in the office or the lab, John loves to be out on the water sailing and racing sailboats. He's also a fan of playing squash, skiing, spending time with his family, and being outdoors. John received his B.Sc. degree with Honors in Biochemistry from McMaster University and his Ph.D. in Biochemistry from McMaster University as well. He then conducted postdoctoral research in the Laboratory of Cell Biology at The Rockefeller University. Next, John served on the Faculty of Medicine and Dentistry at the University of Alberta. Afterwards, he became a founding member at the Institute for Systems Biology where he later served as Senior Vice President and Executive Director of Integrative Biology. While working at the Institute for Systems Biology, John also began conducting research at the Center for Infectious Disease Research where he still works today. In our interview John shares his experiences in life, leadership, and science.

Jun 17, 202437 min

Ep 764764: Pioneering Innovative Solutions in Biotechnology, Engineering, and Materials Science to Advance Medicine - Dr. Robert Langer

Dr. Robert S. Langer is the David H. Koch Institute Professor at the Massachusetts Institute of Technology (MIT). Being one of the eight Institute Professors is the highest honor that can be awarded to a faculty member at MIT. Much of Bob's research is at the interface between materials and medicine. His lab has created nanoparticles and drug delivery systems, engineered tissues and organs for things like artificial skin for burn victims, and made organ-on-a-chip technology to help develop and test new drugs that may someday help patients. When he's not working, Bob enjoys spending time with his family, taking his kids to sporting events, lifting weights, and going on walks with his wife. He received his bachelor's degree in chemical engineering from Cornell University and his Sc.D. in chemical engineering from Massachusetts Institute of Technology. Afterwards, Bob worked as a postdoctoral fellow at the Children's Hospital Boston and at Harvard Medical School. He joined the faculty at MIT in 1978. Since then, Bob has accepted more than 220 major awards and honors, including the U.S. National Medal of Science, the U.S. National Medal of Technology and Innovation (he is one of 3 living individuals to have received both these honors), the Charles Stark Draper Prize (often called the Engineering Nobel Prize), Queen Elizabeth Prize for Engineering, Albany Medical Center Prize, Breakthrough Prize in Life Sciences, Kyoto Prize, Wolf Prize for Chemistry, Millennium Technology Prize, Priestley Medal (highest award of the American Chemical Society), Gairdner Prize, Hoover Medal, Dreyfus Prize in Chemical Sciences, BBVA Frontiers of Knowledge Award in Biomedicine, Balzan Prize, and the Dr. Paul Janssen Award. In 1998, he received the Lemelson-MIT prize, the world's largest prize for invention for being "one of history's most prolific inventors in medicine," and he was inducted into the National Inventors Hall of Fame in 2006. He is an elected Fellow of the Institute of Medicine of the National Academy of Sciences, the National Academy of Engineering, the National Academy of Sciences, and National Academy of Inventors, and the Royal Academy of Engineering. He has been awarded over 1,000 patents and has received 42 honorary doctorate degrees, including degrees from Harvard, Yale, Columbia, and Northwestern. In our conversation, he shares more about his life and science.

Jun 10, 202436 min

Ep 763763: Researching Robotic Systems for Rehabilitation of Stroke and Spinal Cord Injury - Dr. Marcie O'Malley

Dr. Marcie O'Malley is the Stanley C. Moore Professor of Mechanical Engineering, as well as a Professor of Computer Science and Electrical and Computer Engineering at Rice University. Marcie is also an Adjunct Associate Professor in the Departments of Physical Medicine and Rehabilitation at Baylor College of Medicine and at the University of Texas Medical School at Houston. In addition, she is Director of the Mechatronics and Haptic Interfaces Lab at Rice University, Director of Rehabilitation Engineering at TIRR-Memorial Hermann Hospital, and co-founder of Houston Medical Robotics, Inc. The goal of Marcie's research is to use robotic systems to maximize what people can achieve. She is working on incorporating robotics to rehabilitate and restore function in people after spinal cord injury or stroke. To do this, Marcie creates wearable and interactive robots to assist with therapy. Another area of Marcie's research focuses on the use of robots for training via surgical simulations. Outside of her scientific interests, Marcie loves to travel and explore new cities. She is also a mom of eleven year old twin boys, so she spends a lot of time working on school projects, attending sporting events, going to art classes, exploring parks, and visiting museums with them. She received her B.S. in mechanical engineering from Purdue University, and she was awarded her M.S. and Ph.D. in mechanical engineering from Vanderbilt University. Marcie has received recognition for her teaching and research through receipt of the George R. Brown Award for Superior Teaching at Rice University, an Office of Naval Research Young Investigator Award, and an NSF CAREER Award. She has also been named a Fellow of the American Society of Mechanical Engineers. Marcie joined us for an interview to talk about some of her experiences in life and science.

Jun 3, 202444 min

Ep 762762: Understanding How Natural Selection Drives Diversity, Adaptation, and Design - Dr. Ryan Martin

Dr. Ryan Martin is an Assistant Professor in the Department of Biology at Case Western Reserve University. As an Evolutionary Ecologist, Ryan is interested in animal diversity and design. Animals seem to be well adapted to their environment, and Ryan works to understand how diversity, adaptation, and design occur through the action of natural selection. He investigates how the presence of predators, weather conditions, and other environmental features change the way animals survive and produce offspring. In his free time, Ryan enjoys trying new restaurants with his fiancée. They also love to go hiking with their dogs, and Ryan has been honing his photography skills. He received a B.S. in Ecology and Evolution from the University of California, Santa Cruz and was awarded his Ph.D. in Biology from the University of North Carolina at Chapel Hill. Afterward, Ryan conducted postdoctoral research at North Carolina State University and the National Institute for Mathematical and Biological Synthesis in Knoxville, TN before accepting a faculty position at Case Western where he is today. Ryan is here with us today to tell us all about his journey through life and science.

May 27, 202446 min

Ep 761761: Changing Behaviors to Improve Long-Term Health Outcomes in Adults With Neurologic Disease - Dr. Kim Waddell

Dr. Kim Waddell is an Assistant Professor in Physical Medicine and Rehabilitation at the University of Pennsylvania's Perelman School of Medicine as well as a faculty member with the Center for Health Incentives and Behavioral Economics, a Senior Fellow in the Leonard Davis Institute of Health Economics, and Research and Innovation Manager in the Penn Medicine Nudge Unit at the University of Pennsylvania. In addition, Kim is a Research Health Scientist at the VA Center for Health Equity Research and Promotion. Kim's research focuses on behavior change and how to help motivate people to make decisions that are more aligned with their longer term goals. She is particularly interested in physical activity and using approaches from behavioral science to motivate adults who have had a stroke or have Parkinson's disease to increase their daily activity. Another area that Kim is interested in is designing clinical decision support systems and ways to improve decision making to make sure that people are getting the right amount of the right kind of rehabilitation after stroke. When she's not working, Kim tries to go running as often as possible to clear her head and disconnect from technology. She also enjoys cooking, particularly trying new recipes, as well as watching local sports teams and traveling. Kim received her BS in Health Science from Truman State University and her Master's degree in Occupational Therapy from the University of North Carolina at Chapel Hill. She then attended Washington University in St. Louis where she earned her PhD in Movement Science and her Master's degree in Clinical Investigation. Kim conducted postdoctoral research at the VA and Penn before joining the faculty there. Recently, she was awarded the 2024 Academy of Behavioral Medicine Research's Early-Stage Investigator Award, and in our interview, she shares more about her life and science.

May 20, 202435 min

Ep 760760: Unearthing Clues About Our Planet's Past From Tiny Fossils Found in Rock - Dr. Francisca Ikuenobe

Dr. Francisca Ikuenobe is a Professor of Geology and Geophysics at the Missouri University of Science and Technology. In her research, Franca studies rocks to understand the clues they can reveal about the living things, environments, and climates of the past. Franca is particularly interested in the microfossils of pollen, spores, and phytoplankton that are preserved in rock. She uses these to help determine the age of rocks and what they can tell us about the history of an area. Franca loves reading entertainment magazines like Vogue Magazine and watching entertainment news on TV. When Entertainment Tonight is about to start, she drops everything she's doing to watch it. She received her B.Sc. in Geology from the University of Ife in Nigeria (now Obafemi Awolowo University). Afterwards, Francisca worked as a production geologist and subsequently a palynologist for Shell Petroleum Development Company for a year before enrolling in graduate school. She received her M.Sc. in applied geology also from the University of Ife where she next worked as an assistant lecturer. Francisca was awarded a Commonwealth Scholarship Commission Award for her Ph.D. work in Geology at Cambridge University. Following the completion of her Ph.D., Francisca joined the faculty at Missouri S&T where she is today. Francisca has received various awards and honors for her work, including being named an Honorary Global Counselor by Missouri S&T's Office of International and Cultural Affairs, an elected fellow of the American Association for the Advancement of Science, an African Scientific Institute Fellow, an elected fellow of the Geological Society of America, as well as receipt of the Distinguished Service Award from Goretti Old Girls International, Inc. and receipt of the Science and Technology Award from the Nigerian People's Forum. In addition, Francisca has been awarded the Outstanding Teaching Award, Outstanding Students Leaders' Outstanding Student Advocate Award, the Faculty Excellence Award, Sustained Excellence in Teaching Award, and the Woman of the Year Award all from Missouri S&T. Francisca joined us for an interview to talk about some of her experiences in life and science.

May 13, 202437 min

Ep 759759: Dedicated to Antibody Discovery and Development for Research and Therapeutics - Dr. John Majercak

Dr. John Majercak is Head of Antibody Discovery at Lampire Biological Laboratories, a life science company at the forefront of innovation and discovery. At Lampire Biological Laboratories, John works primarily with antibodies, a type of blood protein. He generates new antibodies and provides existing antibodies to companies and academic institutions for use in research, development of antibody therapeutics, and other applications. When he's not at work, John enjoys listening to podcasts and exploring other scientific fields, including physics, astronomy, and space exploration. He also spends his free time doing home renovations, and he's currently working on a bathroom remodel. John received his PhD in Biochemistry from Rutgers University. Afterwards, he completed an industry postdoctoral fellowship at Novartis. Over the next nearly two decades, John worked at several companies, rising in the ranks to hold various positions at Merck, Boehringer Ingelheim, Johnson & Johnson, Bristol Myers Squibb, and Molecular Templates before joining the team at Lampire in 2023. In our interview, John shares more about his life and science.

May 6, 202442 min

Ep 758758: Keeping Your Brain in the Game: Creating Interventions to Optimize Cognition - Dr. Adam Gazzaley

Dr. Adam Gazzaley is a Professor of Neurology, Physiology and Psychiatry and the Founding Director of the Neuroscience Imaging Center at the University of California, San Francisco. Adam is also Co-Founder and Chief Science Advisor of Akili Interactive Labs, a company that is developing therapeutic video games. Much of the research in Adam's lab focuses on aging and how aspects of cognition, like memory and attention, change over our lifespan. They are working to develop new, innovative tools, including engaging video games, to enhance brain function, improve cognition, and improve quality of life. In his free time, Adam can be found spending quality time with friends and family. He is a fan of hanging out over dinner, enjoying live music, hiking, camping, and getting outdoors. He received his M.D. And Ph.D. in Neuroscience at the Mount Sinai School of Medicine. Adam then completed his Internship in Medicine and Clinical Residency in Neurology at the University of Pennyslvania, followed by postdoctoral training in Cognitive Neuroscience at UC, Berkeley before joining the faculty at UCSF where he is today. Adam is the recipient of the Pfizer/AFAR Innovations in Aging Award, the Ellison Foundation New Scholar Award in Aging, the Harold Brenner Pepinsky Early Career Award in Neurobehavioral Science, and the UCSF 150th Anniversary Alumni Excellence Award. He is also an elected Member of the American Society for Clinical Investigation. Adam is here with us today to tell us all about his journey through life and science.

Apr 29, 202442 min

Ep 757757: Developing Molecular Biotechnology Tools for Neural Dynamics Research and Novel Therapeutics - Dr. Lin Tian

Dr. Lin Tian is a Scientific Director at the Max Planck Florida Institute for Neuroscience and Clinical Professor at the University of California, Davis. The main goal of Lin's lab is to develop, leverage, and also share novel optical and molecular tools that can help us to characterize neural signaling and find new treatment targets for neuropsychiatric disorders. In addition to her scientific and leadership roles, Lin is a mom, wife, and daughter. She often spends her free time with her family, driving her two sons to different activities, cheering for them at their swim meets and baseball games, and helping them with homework. Lin also enjoys walking her dog and doing things around the house. She earned her B.S. in Neuroscience from the University of Science and Technology of China and her Ph.D. in Biochemistry, Molecular, and Cellular Biology from Northwestern University. She then completed postdoctoral training at Howard Hughes Medical Institute's Janelia Research Campus. Lin remained at HHMI as a Research Specialist before joining the faculty at the University of California, Davis School of Medicine in 2012. She began her current position at Max Planck in 2023. Lin has received multiple awards and honors, including an NIH New Innovator Award, the W.M. Keck Foundation Award, the Human Frontier Science Program Young Investigator Award, and she has been named a Rita Allen Scholar and Hartwell Scholar. In our interview, she shares more about her life and science.

Apr 22, 202443 min

Ep 756756: Passionately Pursuing Projects on the P53 Tumor Suppressor Protein - Dr. Maureen Murphy

Dr. Maureen Murphy is a Professor and Program Leader in the Molecular and Cellular Oncogenesis Program of the Wistar Institute Cancer Center in Philadelphia. She is also the Associate Vice president for Faculty Affairs and Associate Director For Education and Career Development there. Maureen's research is aimed at understanding and developing cures for cancer. Specifically, they focus on the p53 tumor suppressor protein that is responsible for stopping tumors from forming. When she's not in the lab, you can find Maureen hiking outside with her dogs. She loves nature and thinks dogs are wonderful for reminding us to take a break from our hectic schedules to enjoy life. Maureen is also a fan of traveling, cycling, and yoga. Maureen received her B.S. in biochemistry from Rutgers University and a Ph.D. in molecular biology from the University of Pennsylvania School of Medicine. After graduate school, she completed postdoctoral research at Princeton University. Maureen served on the faculty at the Fox Chase Cancer Center before accepting her current position at the Wistar Institute. Maureen is with us today to tell us all about her journey through life and science.

Apr 15, 202450 min

Ep 755755: Designing, Creating, and Testing Novel Materials with Unique Properties - Dr. Carlos Portela

Dr. Carlos Portela is the Brit and Alex d'Arbeloff Career Development Professor in Mechanical Engineering at MIT. Carlos's research involves designing, making, and testing new types of materials that have unconventional properties. To do this, they rearrange the components of existing materials in three dimensions at the micro or nano scale to create new architected materials. The new materials may absorb a lot of energy upon impact, or be extremely lightweight, but also very stiff. When he's not working, Carlos likes to stay active by running, playing golf, and playing a variety of team sports. He also enjoys exploring new restaurants in Boston, particularly places that serve Asian-Spanish fusion food. He received his bachelor's degrees in aerospace engineering and physics from the University of Southern California, his M.S. and Ph.D. degrees in mechanical engineering from the California Institute of Technology (Caltech). Carlos remained at Caltech to conduct postdoctoral research before joining the faculty at MIT. He was the recipient of an NSF Faculty Early Career Development (CAREER) Award, and he has also been named among MIT Tech Review's 35 Innovators Under 35. In this interview, he shares more about his life and research.

Apr 8, 202435 min

Ep 754754: Hooked on Researching Marine Coastal Ecosystems and Fish Abundance - Dr. Joel Fodrie

Dr. Joel Fodrie is an Assistant Professor in the Institute of Marine Sciences and Department of Marine Sciences at the University of North Carolina at Chapel Hill. Joel studies estuaries which are habitats where freshwater from rivers and streams mixes with the salt water of the ocean. He acts as a sort of detective to investigate how things like salt marshes, sea grasses, and oyster reefs keep this habitat healthy and to determine what may be driving observed changes in fish abundance in these areas. Joel has always loved going out on the water for activities like fishing, surfing, and boating. He got his first boat when he was only 13 years old! In addition, Joel is also an enthusiastic basketball player and reader of Revolutionary Era history books and biographies. He received his undergraduate training in Biology and History from the University of North Carolina at Chapel Hill and went on to receive his Ph.D. in Biological Oceanography from the Scripps Institution of Oceanography at the University of California, San Diego. Afterward, Joel conducted postdoctoral research with the Marine Sciences Consortium at the Dauphin Island Sea Lab. Joel served on the faculty at the University of South Alabama before joining the faculty at the University of North Carolina at Chapel Hill where he is today. Joel is here with us today to tell us all about his journey through life and science.

Apr 1, 202441 min

Ep 753753: Getting a Glimpse into the Most Distant Galaxies in the Universe - Dr. Taylor Hutchison

Dr. Taylor Hutchison is an astrophysicist and a Postdoctoral Fellow at the NASA Goddard Space Flight Center. Taylor uses large telescopes like the James Webb Space Telescope to study the most distant galaxies that we can detect in the universe. Her goal is to answer questions like what kinds of stars are inside these galaxies, how massive the galaxies are, and what elements are present. When she's not working, Taylor engages in a variety of hobbies, crafts, and opportunities to learn new skills. She particularly enjoys reading, hiking, sewing her own clothing, and creatively reusing items that may have otherwise been thrown away. For example, she uses recycled cardboard and newspapers to make baskets and other tools. She received her bachelor's degree in physics from Southwestern University and her Master's and PhD degrees in Astronomy from Texas A&M University. She was the recipient of the Dr. Joseph Newton Graduate Service Award, a University Prestigious Fellowship Scholarship, the Leadership in Equity and Diversity (LEAD) Award, and the Graduate Diversity Excellence Award from Texas A&M University, and she also received a National Science Foundation Graduate Research Fellowship as well. In this interview, Taylor shares more about her life and science.

Mar 25, 202435 min

Ep 752752: The Science Behind the Survival Skills of Cells Under Stress - Dr. Ken Dawson-Scully

Dr. Ken Dawson-Scully is an Associate Professor in the Department of Biological Sciences at Florida Atlantic University. Ken uses the fruit fly as a model to understand how animals have adapted to different kinds of changes in the environment and how they can cope with it. He uses neurophysiology and behavioral genetics approaches to study the impacts of different kinds of stresses, including high temperature and low oxygen. This work has important applications for human conditions like febrile seizures that can occur when the body temperature rises or complications from stroke that deprive parts of the brain of oxygen. Much of Ken's free time is spent with his two kids. His daughter plays basketball and the trombone, and his son is into tennis and the baritone. This means he gets to go to a lot of practices, games, and concerts with his family. Moving from Canada to Florida has turned them into avid beach-goers as well, so they like to enjoy as much sand and sun together as possible. He received his Master's degree in Neurobiology from Queen's University and his PhD in Neurophysiology from the University of Toronto. Ken then conducted postdoctoral research at the University of Toronto before joining the faculty at Florida Atlantic University. In our interview, Ken shares more about his life and science.

Mar 18, 202451 min

Ep 751751: Timely Research on Circadian Clocks and Rhythmic Reorientation in Plants - Dr. Stacey Harmer

Dr. Stacey Harmer is a Professor of Plant Biology in the College of Biological Sciences at the University of California, Davis. Stacey studies different biological rhythms and the circadian clocks within organisms that create and maintain those rhythms. Circadian clocks can be found in various organisms, from bacteria to people. In particular, Stacey is interested in understanding why plants have circadian clocks, how these clocks work in plants, and what aspects of physiology and development these clocks control. Stacey likes to take her mind off research when she's not in the lab by doing yoga and road biking. She and her husband also enjoy cooking and eating their delicious kitchen creations. She received her BA in Biochemistry from the University of California, Berkeley and was awarded her PhD in Biochemistry from the University of California, San Francisco. Afterwards, Stacey conducted postdoctoral research at the Scripps Research Institute in La Joya before joining the faculty at UC, Davis where she has been since 2002. She is the recipient of the American Society of Photobiology's New Investigator Award and was selected as a Chancellor's Fellow at UC Davis. Stacey is with us today to share her exciting experiences in life and science.

Mar 11, 202436 min

Ep 750750: Studying How Cells Control Energy Use and Storage in Response to Hormones and Nutrients - Dr. Alan Saltiel

Dr. Alan R. Saltiel is Distinguished Professor of Medicine and Pharmacology, Maryam Ahmadian Endowed Chair in Metabolic Health, Director of the Institute for Diabetes and Metabolic Health at UC, San Diego, and Director of the UCSD/UCLA Diabetes Research Center. Alan studies how cells that are involved in metabolism decide to take up and store energy, burn energy, or release energy for other cells to use in response to hormones, nutritional cues, and metabolic stress. He is particularly interested in studying cells in liver and fat tissues and better understanding the pathways involved in controlling the metabolic activities of these cells. When he's not working, Alan enjoys exercise and physical activity, including tennis and occasionally basketball. He also likes to read fiction and non-fiction, spend time with friends and family, and experiment with cooking Mediterranean cuisine. He received his bachelor's degree in zoology from Duke University, and his Ph.D. in biochemistry from the University of North Carolina. Afterwards, he conducted postdoctoral research at the Wellcome Research Laboratories. Alan served on the faculty at Rockefeller University before joining Parke Davis Pharmaceutical Research in 1990, where he remained until 2001 when he accepted a position at the University of Michigan. He transitioned to his current positions in 2015. Alan has received numerous awards and honors, including the Rosalyn Yalow Research and Development Award from the American Diabetes Association; the Hirschl Award from Hirschl Trust; the John Jacob Abel, Goodman and Gilman, and Pharmacia-ASPET Awards from the American Society of Pharmacology and Experimental Therapeutics, and he was named a Fellow of the Society in 2022. In addition, Alan is an elected Fellow of the American Association for the Advancement of Science, an elected Member of the American Society of Clinical Investigation, and an elected Member of the National Academy of Medicine. In this interview, Alan shares more about his life and science.

Mar 4, 202440 min

Ep 749749: Progressing Towards an Understanding of the Genes Contributing to Cancer Malignancy - Dr. Erica Golemis

Dr. Erica Golemis is a Professor, Deputy Chief Science Officer, Co-Leader of the Molecular Therapeutics Program, and Director of the High Throughput Facility at the Fox Chase Cancer Center in Philadelphia. In addition, Erica is an adjunct faculty member at the University of Pennsylvania, Drexel University School of Medicine, and the Temple University Lewis Katz School of Medicine. For most of her scientific career, Erica has been conducting cancer research. Her recent work investigates why some cancers are particularly malignant. Erica's research examines what genes cause cancer to change and progress, whether there are genes that can be targeted directly with different treatments to reverse this process, and if there is a therapeutic time window in which they could potentially reverse this process. When Erica finds free time, one thing she loves to do is read. She reads broadly and has been an avid reader since her early childhood. Erica also has fun attending theatre performances. There are multiple excellent theaters in her home city of Philadelphia, and she especially enjoys shows by British playwright Tom Stoppard. She completed her undergraduate studies in biology and English at Bryn Mawr College and was awarded her PhD in biology from the Massachusetts Institute of Technology. Afterwards, Erica conducted postdoctoral research at the Massachusetts General Hospital Department of Molecular Biology and Harvard Medical School department of Genetics before joining the Fox Chase Cancer Center. In this interview, Erica speaks about her experiences in both life and science.

Feb 26, 202456 min

Ep 748748: Figuring Out the Functional Organization and Development of Cortical Circuits in the Brain - Dr. David Fitzpatrick

Dr. David Fitzpatrick is Chief Executive Officer, Scientific Director, and Research Group Leader at the Max Planck Florida Institute for Neuroscience. The brain is important for so many aspects of our daily experiences, including what we perceive, what we think about, how we move, the decisions we make, and more. However, we still know relatively little about how the brain works and how it develops. David's goal is to dive deep into these basic science questions of how the brain works and how it develops. When David isn't hard at work at Max Planck, he spends his time hiking, biking, kayaking, and immersing himself in nature. He has also become a keen photographer, capturing captivating photos of the natural world and memorable moments in his life. David received his B.S. degree in Biology from Pennsylvania State University and his PhD in Psychology and Neuroscience from Duke University. He conducted postdoctoral research at the Medical University of South Carolina and then returned to Duke University as a member of the faculty. Before accepting his current positions at the Max Planck Florida Institute, David was the James B. Duke Professor of Neurobiology and Director of the Institute for Brain Sciences at Duke University. David has received numerous awards and honors over the course of his career for his outstanding research and teaching, including the 2011 Ellis Island Medal of Honor from the National Ethnic Coalition of Organizations, the Alfred P. Sloan Research Award, the Cajal Club Cortical Discoverer Award, the McKnight Neuroscience Investigator Award, and the Excellence in Basic Science Teaching Award from Duke University School of Medicine. David joined us for an interview to share his experiences in life and science.

Feb 19, 202439 min

Ep 747747: Conducting Research to Conserve Colorado's Rare Plants - Dr. Jennifer Ramp Neale

Dr. Jennifer Ramp Neale is Director of Research and Conservation at the Denver Botanic Gardens. She is also an Adjunct Professor of Biology at the University of Northern Colorado and the University of Colorado Denver. The Denver Botanic Gardens is an accredited museum, a public nonprofit organization, and a research institution, so Jenny has a variety of different roles. She oversees the research conducted there, communicates their findings and the importance of science to different audiences, and works closely with land managers/owners to provide information on the local plants to help guide land management decisions. Jenny's research focuses on applied conservation of plants, particularly rare and endangered species in Colorado. Outside of work, Jenny is a wife, mother, and outdoors enthusiast. She enjoys being active outdoors with her family playing soccer, skiing, camping, hiking, and generally having fun outside. Jenny's passion for identifying plants and mushrooms is contagious, and as a result, her family has also become quite knowledgeable about the plants of Colorado. She received her B.S. in Biology from Rhodes College and her Ph.D. in Ecology and Evolutionary Biology from the University of Colorado. Afterwards, Jenny conducted postdoctoral research in community genetics at the University of Colorado. Jenny's previous positions include Manager of Research Programs and Associate Director of Research at the Denver Botanic Gardens, as well as Conservation Genetic Consultant with LSA Associates and Solano County Water Agency through the University of Colorado Museum. Jenny is the recipient of the 2012 Partners in Mission Recovery Champion Award as part of the Rare Plant Conservation Initiative from the U.S. Fish and Wildlife Service. She joined us for an interview to talk about her experiences in life and science.

Feb 12, 202439 min

Ep 746746: Investigating the Intersection of Nutrition and Bacterial Infection and Pathogenesis - Dr. Eric Skaar

Dr. Eric Skaar is Director of the Institute for Infection, Immunology and Inflammation, Director of the Division of Molecular Pathogenesis, the Ernest W. Goodpasture Chair in Pathology, and Vice Chair for Research and a University Distinguished Professor in the Department of Pathology, Microbiology, and Immunology at Vanderbilt University. Eric is a bacteriologist who studies the impact of nutrition on infectious disease. His research examines how the food we eat affects our susceptibility to bacterial infection and how the bacteria that infect us get food once they are inside our bodies. He earned his B.S. in Bacteriology from the University of Wisconsin-Madison, his Ph.D. in Immunology and Microbial Pathogenesis from Northwestern University, and his M.P.H. in Epidemiology and Biostatistics from Northwestern University. Afterwards, he completed a postdoctoral fellowship in microbiology at the University of Chicago before joining the faculty at Vanderbilt in 2005. Eric has received numerous awards and honors for his research including being named an American Asthma Foundation Scholar, receipt of Vanderbilt University's Stanley Cohen Award for Excellence in Research Bridging Disciplines, the Pfizer ASPIRE Young Investigator Award, the Vanderbilt Chancellor's Award for Research, and more. He has also won a variety of awards for exceptional mentorship and teaching, including the Vanderbilt Molecular Pathology and Immunology Graduate Program Teacher of the Year Award, the F. Peter Guengerich, Ph.D., Award, the Vanderbilt University Medical Center Postdoc Mentor of the Year Award, and others. In addition, he is an elected Fellow of the American Association for the Advancement of Science and the American Academy of Microbiology. In our interview, Eric shares more about his life and science.

Feb 5, 202449 min

Ep 745745: Astrophysicist Radiating Enthusiasm for Research on Plasma Physics and Cosmic Rays - Dr. Ellen Zweibel

Dr. Ellen Zweibel is the W. L. Kraushaar Professor of Astronomy and Physics, and the Vilas Distinguished Achievement Professor at the University of Wisconsin, Madison. Ellen is a theoretical astrophysicist who specializes in plasma astrophysics. Her studies examine electricity and magnetism in the cosmos, including phenomena like sun spots, the solar cycle, and high energy electromagnetic emissions (e.g. x-rays, gamma rays, and radio waves) from stars and galaxies. Ellen's interests outside of science include creative writing, art, and exercise. She has recorded her thoughts and sketches in a journal since 1977, and drawing is a wonderful way for Ellen to see details in her surroundings that she might otherwise miss. In addition, Ellen has explored her artistic side through sculpting clay and painting. As far as exercise, Ellen runs at least 45 minutes every day. She received her bachelor's degree in Mathematics from the University of Chicago and her PhD in Astrophysical Sciences from Princeton University. Ellen served as a faculty member at the University of Colorado for over 20 years before joining the faculty at the University of Wisconsin in 2003. Ellen has received numerous awards and honors during her career, including being elected as a Fellow of the American Physical Society and being awarded the American Physical Society's Maxwell Prize for Plasma Physics. Ellen joined us for an interview to talk about her experiences in life and science.

Jan 29, 202438 min

Ep 744744: Innovating Drug Discovery with Novel Approaches to Target Disease-Causing Proteins - Dr. Ryan Potts

Dr. Ryan Potts is VP of Research and Head of the Induced Proximity Platform at Amgen that works on ways to bring two or more molecules in close proximity to each other to tackle drug targets that are currently considered "undruggable." Ryan conducts early-stage research to discover new high-impact medicines for serious diseases that have a high unmet medical need. Their work examines biological pathways, drug targets, disease drivers, and new ways to create drugs that have the desired effects. He also leads Amgen's Research & Development Postdoctoral Fellows Program. Outside of science, Ryan enjoys spending quality time with his family and his kids. They enjoy exploring the natural world, hiking, and exploring the nearby Santa Monica Mountains and local beaches. Ryan is also an avid traveler and sports fan. Ryan received his BS in biology from the University of North Carolina at Chapel Hill, and he was awarded his PhD in cellular and molecular biology from UT Southwestern Medical Center. After completing his PhD, Ryan served on the faculty at UT Southwestern Medical Center for eight years before accepting a position on the faculty at St. Jude Children's Research Hospital. He joined the team at Amgen in 2020. In this interview, he shares more about his life and science.

Jan 22, 202442 min

Ep 743743: Advancing Tissue Engineering, Drug Discovery, and Drug Delivery - Dr. Pankaj Karande

Dr. Pankaj Karande is an Associate Professor in Chemical and Biological Engineering at Rensselaer Polytechnic Institute. Pankaj was trained as a chemical engineer, and his research aims to apply engineering approaches and technology to solve problems in biology and healthcare to improve the quality and quantity of human life. Projects in his lab span areas such as drug discovery, drug delivery, biomaterials, diagnostics, and more. When he's not working, Pankaj loves to cook, and experimenting with different recipes has been a great way to relieve stress. He was awarded his B.S. in Chemical Engineering from Mumbai University Institute of Chemical Technology and his Ph.D. in Chemical Engineering from the University of California, Santa Barbara. Pankaj was awarded an Anna Fuller Postdoctoral Fellowship in Molecular Oncology, and he conducted postdoctoral research in the Center for Cancer Research at Massachusetts Institute of Technology before joining the faculty at Rensselaer. Pankaj has received a variety of awards and honors in his career, including the Excellence in Classroom Instruction Award and the Outstanding Teaching Award from Rensselaer Polytechnic Institute. He also received the Alzheimer's Association New Investigator Research Award, the Goldhirsh Brain Tumor Research Award, and a Bronze Edison Award in the Best New Product in Science and Medical Category. In addition, he has been issued multiple patents in the areas of Transdermal Formulation Discovery and Novel High Throughput Screening Platforms. In our interview, Pankaj shares more about his life and science.

Jan 15, 202440 min

Ep 742742: Studying Hair Follicles and Skin to Better Understand Tissue Development and Regeneration - Dr. Claire Higgins

Dr. Claire Higgins is a Reader (faculty) in Tissue Engineering and Regenerative Medicine in the Department of Bioengineering at Imperial College London. She is also President of the European Hair Research Society and Vice President of the Institute of Trichologists, a professional association for researchers who study the hair and scalp. Claire teaches and conducts research in the areas of tissue engineering and regenerative medicine. She uses skin and hair follicles as models to better understand how tissues respond to injury, heal wounds, and repair after disease. Outside of science, making pottery has been one of Claire's favorite pastimes since she took her first classes as a postdoc. She enjoys making items like bowls, vases, and lamp bases on her pottery wheel in her studio during her free time. Claire received her B.Sc. in natural sciences and her PhD in skin developmental biology from Durham University in England. Afterwards, she conducted postdoctoral research at Columbia University. She worked as an Associate Research Scientist at Columbia University before joining the faculty and starting her laboratory at Imperial College London in 2014. In our interview, she shares more about her life and science.

Jan 8, 202441 min

Ep 741741: Engineering Microbes to Improve Equity in Human and Environmental Health - Dr. Ariel Furst

Dr. Ariel Furst is the Paul M. Cook Career Development Professor in the Department of Chemical Engineering at Massachusetts Institute of Technology (MIT). In her research, Ariel has been using microbes to address problems surrounding human health, environmental remediation, and sustainability. Her lab focuses on energy equity by developing new technologies that are accessible to people who haven't had access to technology but are negatively impacted by it. She is also working towards energy justice by developing technology and approaches to remediate prior harms to marginalized communities. In her free time, Ariel and her husband enjoy experimenting with new recipes in the kitchen. She also likes to spend time outdoors hiking, jogging, and doing fun activities like apple picking with her lab members. She received her B.S. degree in chemistry from the University of Chicago and her PhD in chemistry from the California Institute of Technology. Afterwards, she was awarded a Beckman Foundation Postdoctoral Fellowship, and she conducted postdoctoral research at the University of California, Berkeley before joining the faculty at MIT in 2019. Ariel has received a variety of awards during her career, including the NIH Director's New Innovator Award, the Camille Dreyfus Teacher-Scholar Award, the Marion Milligan Mason Award from American Association for the Advancement of Science, the Women in Chemical Engineering Rising Star Award from the American Institute of Chemical Engineers (AIChE), and the Outstanding Mentor Award from the MIT Undergraduate Research Opportunities Program. She was also named a Scialog Fellow for Negative Emissions Science. In our interview, she shares more about her life and science.

Jan 1, 202442 min

Ep 740740: Targeting Complex Sugars on Cell Surfaces to Treat Multiple Sclerosis and Cancer - Dr. Michael Demetriou

Dr. Michael Demetriou is Director of the National Multiple Sclerosis Society Designated Comprehensive Care Clinic, Professor of Neurology, and Chief of the Division of Multiple Sclerosis and Neuroimmunology at the University of California, Irvine (UCI) School of Medicine. In his research, Mike studies the biological roles of complex sugars called glycans. Glycans are mostly found outside of cells and on cell surfaces. They form a dense forest around the surface of cells and can interact with other proteins to regulate cellular function through interactions with other cell surface proteins. Mike's lab is interested in how these cell surface glycans influence biology and disease, particularly in autoimmune diseases like multiple sclerosis (MS) and in diseases like cancer where there are commonly abnormalities in these glycans. Mike is also a big fan of the Toronto Maple Leafs hockey team. While he doesn't play hockey himself anymore, he loves watching professional hockey games and seeing the Maple Leafs play whenever they are in town. He was awarded his MD and his PhD in molecular genetics from the University of Toronto. Mike completed his residency in Neurology at the University of Toronto as well and completed his postdoctoral fellowship at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital in Toronto. He has received a variety of awards and honors in his career, including being named a Fellow of the Royal College of Physicians and Surgeons in Canada. In addition, he has received UCI's College of Medicine Committee on Research Award, the Health Science Partners Research Award, the Academic Senate Distinguished Service Award, and the Dr. S. Van Den Noort Research Award for Junior Faculty. In our interview, Mike shares more about his life and science.

Dec 25, 202341 min

Ep 739739: Studying Cell Division to Better Understand and Improve Cancer Therapies - Dr. Beth Weaver

Dr. Beth Weaver is a Professor in the Department of Cell and Regenerative Biology and the Department of Oncology/McArdle Laboratory for Cancer Research at the University of Wisconsin-Madison School of Medicine and Public Health. She is co-Leader of the Developmental Therapeutics Program at the University of Wisconsin Carbone Cancer Center. Beth studies a group of commonly used chemotherapy agents to better understand how they work, who will respond to these treatments, and how to make resistant tumors more sensitive to these drugs. Outside of work, Beth enjoys spending time with her family. She, her husband, and their two children enjoy making fun group Halloween costumes, and she also brings this creativity into entertaining and hosting themed parties. Beth received her B.S. in biochemistry from Brown University and her Ph.D. in biomedical sciences from the University of California, San Diego. Afterwards, Beth conducted postdoctoral research at the Ludwig Institute for Cancer Research before joining the faculty at the University of Wisconsin-Madison. She has received various awards and honors during her career. These have included receipt of the Bothwell Prize and the Women's Health Research Mentorship Award from UW-Madison. In addition, she has been named an American Cancer Society Research Scholar, a Romnes Faculty Fellow by the Wisconsin Alumni Research Foundation, and a University of Wisconsin Carbone Cancer Center Ride Scholar. In this interview, she shares more about her life and science.

Dec 18, 202338 min

Ep 738738: Combining Geology and Microbiology to Investigate Modern and Ancient Microbes - Dr. Magdalena Osburn

Dr. Magdalena Osburn is an Associate Professor in the Department of Earth and Planetary Sciences at Northwestern University. Maggie's research brings together microbiology and geology to understand biological activity in different environments in the past and present. She studies unique microbes that live in extreme environments like deep mines, hot springs, and caves. When she's not working, Maggie likes to go hiking, backpacking, and generally be outside exploring nature. When she's able to get away, she loves going on road trips to enjoy the splendor of the mountains in Montana. At home, Maggie also spends her time doing yoga, running, and knitting. She received her bachelor's degree in Earth & Planetary Sciences and Environmental Studies from Washington University in St. Louis. Afterwards, she enrolled in graduate school at the California Institute of Technology where she earned her M.S. and Ph.D. degrees in geobiology from the Division of Geological and Planetary Sciences. Next, Maggie conducted postdoctoral research at the University of Southern California before joining the faculty at Northwestern University. Maggie has received a variety of awards and honors during her career. She was the recipient of a Packard Fellowship Award in 2017, she has recently received the Sulzman award for teaching and mentoring from the American Geophysical Union, and she has also been named a CIFAR Fellow by the Canadian Institute for Advanced Research and an AT&T Fellow by Northwestern University. In this interview, Maggie shares more about her life and science.

Dec 11, 202349 min

Ep 737737: Investigating the Mechanics of How Cells Move in Cancer and the Immune System - Dr. Erdem Tabdanov

Dr. Erdem Tabdanov is Assistant Professor in the Department of Pharmacology at Penn State College of Medicine and also a Member of the Penn State Cancer Institute. He studies the mechanical and structural aspects of cells to better understand how cells physically move, sense their environments, and accomplish their various functions. This is very relevant to cancer biology and understanding the immune system. Some of Erdem's hobbies outside of science include working out at the gym, calligraphy, sketching, digital art, and other visual arts. He is also considering adopting a cat. His interest in digital art emerged from his desire to put the story of his research together in compelling figures and schematics for journal articles. He received his bachelor's degree in biotechnology and his MSc in chemistry and molecular and cellular biotechnology from Lomonosov Moscow State Academy of Fine Chemical Technology (MITHT). He was awarded his PhD in cancer research from L'Institut Curie in Paris. Afterwards, Erdem conducted postdoctoral research at the University of Pennsylvania and Columbia University. He then served in the 82nd Airborne Division of the U.S. army for four years. Erdem completed a postdoctoral fellowship at the University of Minnesota before joining the faculty at Penn State where he is today. In this interview, Erdem shares more about his life and science.

Dec 4, 202354 min

Ep 736736: Studying How Food Influences Our Health and Behavior - Dr. Alexis Wood

Dr. Alexis "Lekki" Wood is Associate Professor at USDA/ARS Children's Nutrition Research Center in the Division of Pediatrics-Nutrition at Baylor College of Medicine. Research in Lekki's lab aims to better understand how food influences our health. She examines the full chain of changes that occur from the moment food is put into our mouths, trough digestion and absorption of particular molecules, to where those molecules go and how they affect our organs. Outside of work, you can find Lekki working out at the gym and spending quality time with her two children and their German shepherd. She is also a Lego builder and a competitive Pokemon card player along with her son. She received her BSc with honors in Psychology and from the University of Warwick. Afterwards, she completed her Postgraduate Certificate in Education at the University of Cambridge. Lekki enrolled in graduate school at King's College London where she earned her MSc in social, genetic, and developmental psychiatry and her PhD in statistical genetics. Next, she conducted postdoctoral research at the University of Alabama focusing on statistical genetics and epidemiology. Lekki served on the faculty at The University of Texas, Health Sciences Center for about two years before joining the faculty at Baylor College of Medicine where she is today. Lekki has received a variety of awards and honors for her work, including the Young Investigator Award from the International Congress on ADHD and the Young Investigator Award from the Department of Pediatrics at Baylor College of Medicine. In addition, she has received the Scott Grundy Award for Excellence in Metabolism Research and the Mark Bieber Award for Excellence in Nutrition Research, both from the American Heart Association. She was also named a Fellow of the American Heart Association in 2015. In our interview, she shares more about her life and science.

Nov 27, 202345 min

Ep 735735: Growing Our Understanding of the Development, Regeneration, and Evolution of Teeth - Dr. Gareth Fraser

Dr. Gareth Fraser is an Associate Professor in the Department of Biology at the University of Florida. Gareth is a developmental biologist interested in how things form during development, how they are recreated during regeneration, and how features develop and persist on evolutionary timescales. His lab typically examines these questions looking at oral teeth and dermal denticles (tooth-like structures) in unusual fish like pufferfish, hammerhead sharks, and ghost sharks (chimaera). When he's not working, Gareth enjoys being outside in nature, playing soccer, scuba diving, and hunting for fossils in the creek near their home. He and his two young daughters have also been having fun exploring the mysterious realm of cryptozoology and reading books about monsters. Gareth received his bachelor's degree in palaeobiology and evolution from the University of Portsmouth, his master's degree in evolutionary biology and systematics from the University of Glasgow, and his PhD in evolutionary developmental biology from King's College London. Afterwards, Gareth conducted postdoctoral research at the Georgia Institute of Technology. He served on the faculty at The University of Sheffield for about nine years before joining the faculty at the University of Florida in 2018. In this interview, he shares more about his life and science.

Nov 20, 20231h 11m

Ep 734734: Examining the Role of Metabolism in Cancer and Response to Cancer Treatment - Dr. Rachel Perry

Dr. Rachel Perry is Assistant Professor of Medicine (Endocrinology) and of Cellular and Molecular Physiology at the Yale University School of Medicine. Rachel's scientific training focused on how our bodies use nutrients to stay healthy and what goes wrong in diseases like obesity and diabetes. In her current lab, she applies this background to better understand how changes in metabolism (nutrient supply) may affect cancer and how our bodies respond to cancer treatments. In her free time, Rachel enjoys spending time with her family, playing with their Labradoodle puppy, and going on walks in the fantastic fall weather. She is also an avid home chef, and she applies her scientific precision to prepare delicious meals for friends and family. She was awarded her B.S. in Biomedical Engineering and her Ph.D. (with Distinction) in Cellular & Molecular Physiology from Yale University. Afterwards, she remained at Yale for postdoctoral training in internal medicine and endocrinology, and she joined the Yale faculty in 2018. Rachel has received a variety of awards and honors for her research, including the American Physiological Society New Investigator Award, an R37 MERIT Award from the National Institutes of Health, the Translational Science Research Prize from the Yale Cancer Center, the Melanoma Research Alliance Young Investigator Award, the Rising Stars in Cancer Metabolism Award, the Breakthrough of the Year Award from the Yale Cancer Signaling Networks Program, and the Translational Science Research Prize from the Yale Cancer Center. In addition, she was named a Kingsley Fellow of the Yale University School of Medicine. In our interview, she shares more about her life and science.

Nov 13, 202345 min

Ep 733733: Using Microbes to Sustainably Produce Valuable Chemicals and Degrade Toxic Compounds - Dr. Susie Dai

Dr. Susie Dai is an Associate Professor in the Department of Plant Pathology and Microbiology at Texas A&M University. She is also Director of the Biomonitoring Program in the Iowa State Hygienic Laboratory, leading the Iowa Statewide Biomonitoring public health surveillance. Susie works at the interface of chemistry and biology, and her research leverages microorganisms like bacteria and fungus to synthesize chemicals of value or degrade poisonous chemicals. This work has important applications for developing sustainable methods to produce chemicals and breaking down dangerous chemicals that are very stable. In addition, Susie's work also includes biomonitoring where they examine exposure to toxic chemicals from private wells and other environmental sources. When she's not at work Susie enjoys reading and hanging out with her family, including her two wonderful daughters. Susie received her BS degree in Chemistry from Fudan University, and her PhD in Chemistry from Duke University. Afterwards, she conducted postdoctoral research with the Scripps Research Institute and Oak Ridge National Laboratory. Next Susie began working as a Research Assistant Professor and was promoted to Research Associate Professor at Texas A&M in the Office of the Texas State Chemist. Subsequently, she served as Associate Director of the Iowa State Hygienic Laboratory at the University of Iowa and Director of the Environmental Health Division. She returned to the Texas A&M faculty in 2019. In this interview, Susie shares more about her life and science.

Nov 6, 202339 min

Ep 732732: Applying Molecular Biology Tools to Characterize Genes and Enhance Crop Species - Dr. Ralph Dewey

Dr. Ralph Dewey is the Philip Morris Professor of Crop and Soil Sciences and Adjunct Professor of Plant and Microbial Biology at North Carolina State University (NCSU). Ralph uses the tools of molecular biology to identify and characterize genes of agronomic importance in crop species. When possible, he and his team alter those genes in ways that add value to the crop above and beyond what can be attained with traditional breeding approaches. Ralph and his team have done important work on the genetics of tobacco plants to decrease the hazards of smoking for people who still smoke. When Ralph has free time, he enjoys hanging out with his wife at their nearby beach condo and also watching college sports (particularly football and basketball). In addition, Ralph is working on writing his first novel. He was awarded his B.S. degree in biology from Utah State University, followed by his M.S. and Ph.D. in Crop Science from North Carolina State University. Afterwards, Ralph received an NSF Postdoctoral Research Fellowship in Plant Biology to conduct postdoctoral research at the Waksman Institute at Rutgers University. Ralph joined the faculty at NCSU in 1991. He has been issued 34 U.S. Patents for his discoveries in plant biotechnology, with several more pending, and he was awarded NCSU's Philip Morris endowed Professorship in 2009 for his research on harm reduction in tobacco. In this interview, Ralph shares more about his life and science.

Oct 30, 202346 min

Ep 731731: Investigating the Mechanisms of Signaling and Regulation in Protein Complexes - Dr. Denise Okafor

Dr. C. Denise Okafor is an Assistant Professor of Biochemistry and Molecular Biology, and of Chemistry at Pennsylvania State University. Many of the medications we take work by binding to a particular target and either turning off whatever is causing a problem or turning something on that is not working correctly. Denise's research examines how small molecules like drugs find and interact with the targets they are supposed to interact with. She is particularly interested in proteins that can be turned on or off by the small molecules/drugs that they bind with. While science is a large part of Denise's life, she also enjoys reading and writing fiction. Lately, she has been spending much of her free time with her kids, learning dances from Youtube videos and hanging out together. She received her B.S. in biomedical chemistry from Oral Roberts University and was awarded her M.S. in chemistry and a Ph.D. in biochemistry from Georgia Institute of Technology. Afterwards, Denise was selected to complete an Institutional Research and Academic Career Development Award from the NIH to conduct postdoctoral research at Emory University and teach at Morehouse and Spelman colleges in Atlanta. Denise has received a variety of awards and honors for her work, including a Burroughs Wellcome Fund Career Award at the Scientific Interface, an NSF CAREER Award for early investigators, and the NIH Director's New Innovator Award. In addition, she has been named a Keystone Symposia Fellow and a Kavli Foundation Fellow. In our interview, Denise talks more about her life and science.

Oct 23, 202336 min

Ep 730730: Using Chemical Biology to Clarify the Roles of Carbohydrates - Dr. Laura Kiessling

Dr. Laura Kiessling is the Novartis Professor of Chemistry at Massachusetts Institute of Technology (MIT) and Member of the Broad Institute. Laura's research focuses on carbohydrates, particularly all of the different carbohydrates found on the surfaces of cells. We still know relatively little about the functions of these carbohydrates, and Laura is eager to learn more. When she's not doing science, Laura likes being active through rowing, kayaking, cycling, lifting weights, or doing yoga. She also likes to spend her free time cooking, hiking, camping, and enjoying art. She received her BS degree in chemistry from MIT and her Ph.D. degree in organic chemistry from Yale University. After two years at the California Institute of Technology as an American Cancer Society Postdoctoral Fellow, she joined the faculty of the University of Wisconsin, Madison in 1991. She returned to MIT in 2017. Laura has received numerous awards over the course of her career, including the Ronald Breslow Award in Biomimetic Chemistry, the Centenary Prize from the Royal Society of Chemistry, the Tetrahedron Prize for creativity in Organic Chemistry or Bioorganic & Medicinal Chemistry, the Gibbs Medal, from the Chicago Chapter of the American Chemical Society, the Vilas Distinguished Faculty Award from UW-Madison, and others. Laura is an elected Member of the National Academy of Sciences, the National Academy of Medicine, the American Academy of Microbiology, and the American Academy of Arts & Sciences, and American Philosophical Society, as well as an elected Fellow of the American Association for the Advancement of Science. She has been awarded a Guggenheim Fellowship, an American Cancer Society Fellowship, a MacArthur Foundation Fellowship, and an Alfred P. Sloan Foundation Fellowship. She is also the founding Editor-In-Chief of the journal ACS Chemical Biology. In this interview, Laura shares more about her life and science.

Oct 16, 202343 min

Ep 729729: Studying Synaptic Plasticity to Understand How the Brain Learns and Adapts - Dr. Nicole Calakos

Dr. Nicole Calakos is the Lincoln Financial Group Distinguished Professor of Neurobiology and Chief of the Movement Disorders section in Neurology at Duke University Medical Center. Research in Nicole's lab examines how the brain learns and adapts to experiences. She studies synaptic plasticity, from the levels of molecules, cells, cell circuits, and behaviors, to understand what goes wrong in disease and how we can harness brain processes to address disease. When she's not working, Nicole enjoys being outdoors, playing sports, running, going mountain biking, and participating in mountain bike races. Her favorite indoor activities include creative cooking and spending time with family and friends. Nicole was awarded her MD and PhD degrees from Stanford University. Afterwards, she completed an internship in Medicine and Residency in Neurology at the University of California, San Francisco School of Medicine. She conducted postdoctoral research at Stanford University before joining the faculty at Duke University in 2005. Nicole has received numerous awards and honors in her career, including the 2023 Korsmeyer award from the American Society of Clinical Investigation and being named an elected Member of the U.S. National Academy of Medicine, a Fellow of the American Association for the Advancement of Science, and a Fellow of the American Society of Clinical Investigators. In our interview, Nicole shares more about her life and science.

Oct 9, 202344 min

Ep 728728: Researching Risk Factors and Therapies for Blood Clots in the Lungs and Legs - Dr. Alex Spyropoulos

Dr. Alex Spyropoulos ("Dr. Spy") is a Professor of Medicine at the Hofstra Northwell School of Medicine as well as System Director of Anticoagulation and Clinical Thrombosis Services for the multi-hospital Northwell Health System. In addition, Dr. Spy is a Professor of the Merinoff Center for Patient-Oriented Research as part of the Feinstein Institute for Medical Research. As a thrombologist, Dr. Spy studies blood clots. Many people worldwide are either at risk for blood clots or have existing clots. He focuses on venous thromboembolism primarily in the lungs and legs. These blood clots could cause morbidity or mortality, and many people are not familiar with the risks, common symptoms, or the situations in which clots may occur. Outside of work, Dr. Spy loves spending time with his wife and his young kids. Lately, they've been enjoying apple picking, hay rides, pumpkin carving, and apple carving. His other hobbies include sailing, snowboarding and mountain biking. He received his MD from the University of Pennsylvania School of Medicine, and he completed his internship and residency in internal medicine at the University of New Mexico Health Sciences Center. Dr. Spy is a recipient of the Lovelace Clinic Foundation Excellence in Education Award, as well as a Fellow of the American College of Physicians, the American College of Chest Physicians, the International Academy of Clinical and Applied Thrombosis/Haemostasis, and the Royal College of Physicians in Canada. In this interview, he speaks with us about his life and science.

Oct 2, 202340 min

Ep 727727: Investigating Insidious Insects in the Field of Agricultural Pest Management - Dr. Erin Hodgson

Dr. Erin Hodgson is an Associate Professor and Extension Entomologist at Iowa State University. She specializes in insects in agriculture, often focusing on corn and soybean crops. Erin also works with people like farmers, crop consultants, people in the agricultural industry, regulators, and people in pest management to best manage insect pests in an agricultural landscape. Erin spends her free time outside enjoying the company of her husband and two dogs. She is also an Assistant Coach for the Iowa State University Women's Rugby Club and dedicates a lot of her time in the evenings to helping coach the team. She received her undergraduate training in Biology and Botany and her M.S. in Entomology from North Dakota State University. Erin was awarded her Ph.D. in Entomology from the University of Minnesota, followed by a postdoctoral research position also at the University of Minnesota. Erin served on the faculty at Utah State University before joining the faculty at Iowa State where she is today. Erin has received many awards and honors in her career, including the Editor's Choice Award from the Journal of Soil and Water Conservation, the Iowa State University Outreach and Extension New Professional Award, and multiple awards from the Entomological Society of America for her educational and outreach efforts. In addition, Erin is co-host of the "Soybean Pest Podcast" with her colleague Matt O'Neal. Erin is with us today to tell us all about her journey through life and science.

Sep 25, 202342 min

Ep 726726: Mechanical Engineer Making Miniature Mobile Robots - Dr. Sarah Bergbreiter

Dr. Sarah Bergbreiter is an Associate Professor in the Department of Mechanical Engineering with a joint appointment in the Institute for Systems Research at the University of Maryland. Sarah's research involves building and conducting experiments with tiny locomoting robots that are about the size of ants. They also apply the same technologies used in their tiny robots to build better sensors and actuators for bigger robots to help improve performance of these robots. Spending time with her family is a big part of Sarah's life outside of work. Her kids enjoy swimming, playing with legos, and building things. Sarah also spends her free time swimming and playing water polo. She received her B.S.E. degree in electrical engineering from Princeton University and was awarded her M.S. and Ph.D degrees in electrical engineering from the University of California at Berkeley where she focused on microrobotics. Sarah has been the recipient of multiple awards for her outstanding work including the DARPA Young Faculty Award, an NSF CAREER Award, the Presidential Early Career Award for Scientists and Engineers, and Sarah gave a TED Talk in 2015. Sarah joins us for an interview to discuss her life and work.

Sep 18, 202340 min

Ep 725725: Improving How We Diagnose and Treat Certain Blood Clotting Conditions - Dr. Anand Padmanabhan

Dr. Anand Padmanabhan is a pathologist, transfusion medicine physician, and Associate Professor of Laboratory Medicine and Pathology at the Mayo Clinic. Anand studies blood clotting, also known as "thrombosis". He is working on a particular type of blood clotting that can occur when our bodies produce antibodies for proteins or other molecules inside or on the surface of blood platelets. Anand is interested both in finding better ways to diagnose and to treat patients with these potentially deadly diseases. When he's not working, Anand loves spending time with his wife, their 15-year-old son, and their two dogs. They enjoy watching movies and traveling together across the U.S. and around the world. He received his Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.) degree from Thanjavur Medical College and completed a Clinical Internship in Medicine and Surgery at LLR and Associated Hospitals in India. He was awarded his PhD in biochemistry from Brown University. Afterwards, Anand completed his residency in clinical pathology at Columbia University and New York Presbyterian Hospital and transitioned into a Fellowship in transfusion medicine at the University of Pittsburgh. Anand worked at the Blood Center of Wisconsin and the Medical College of Wisconsin from 2010 - 2019, and he joined the Mayo Clinic in 2020. Anand has received various awards and honors over the course of his career, including the JN Tata endowment for the higher education of Indians, National Blood Foundation Award for Innovative Research, ASFA Lecturer award, and Choosing Wisely Champion Award from the American Society for Apheresis, and he was recently inducted into the National Blood Foundation Hall of Fame. In this interview, he shares more about his life and science.

Sep 11, 202342 min

Ep 724724: Heading Up Research Designing New Materials for Helmets to Prevent Brain Injury - Dr. Ellen Arruda

Dr. Ellen Arruda is the Maria Comninou Collegiate Professor of Mechanical Engineering with joint appointments as Professor of Biomedical Engineering, as well as Macromolecular Science and Engineering at the University of Michigan. Ellen studies the mechanical behavior of soft materials, including polymers, plastics, and soft tissues of the body. Her research group focuses on understanding how to design with soft materials so the materials don't break in different applications, as well as how to design replacements for soft tissues in our bodies when they are damaged. Ellen's hobbies include running, cooking, and knitting. Running is one of her favorite ways to get exercise and generate great ideas for her work. She is a skilled sweater knitter who learned how to crochet from her mother and picked up knitting from her mother-in-law. She received her B.S. with Honors in Engineering Science and her M.S. in Engineering Mechanics from Pennsylvania State University. Ellen was awarded her Ph.D. in Mechanical Engineering from the Massachusetts Institute of Technology. She joined the faculty at the University of Michigan afterwards in 1992. Ellen has received numerous awards and honors for her outstanding research, teaching, and service, including the Ann Arbor Spark Best of Boot Camp award, the Excellence in Research Award from the American Orthopaedic Society for Sports Medicine, the Ted Kennedy Family Team Excellence Award from the University of Michigan College of Engineering, the Research Excellence Award from the College of Engineering at the University of Michigan, the Cadell Memorial Award, the Outstanding Engineering Alumnus Award from the Pennsylvania State University, the Distinguished Faculty Achievement Award from the University of Michigan, and the Trudy Huebner Service Excellence Award from the College of Engineering at the University of Michigan. Ellen is a Fellow of the American Society of Mechanical Engineers, the American Academy of Mechanics, and the Society of Engineering Science. She was also named a Centennial Fellow of the Department of Engineering Science and Mechanics at Pennsylvania State University. She was also recently named a Member of the National Academy of Engineering. Ellen joined us for an interview to discuss her experiences in her career, her life, and her engineering research.

Sep 4, 202339 min

Ep 723723: Analyzing Complex Networks of Plant-Animal Interactions - Dr. John Kress

Dr. John Kress is a Distinguished Scientist and Curator of Botany at the Smithsonian's National Museum of Natural History. John's research involves exploring the natural world and all the organisms that make up the natural world. Since graduate school, he has been exploring different areas, particularly tropical areas, to determine what grows there now, what grew there in the past, and how the plants and animals there interact. Not only does John enjoy investigating the natural world at work, he also enjoys spending his free time outside exploring nature. John often goes on walks or hikes with his wife and dog to see nature in action. In addition, John is an avid gardener. Among the plants he cultivates in his own yard are some of the ginger and banana plants that he studies. John received his B.A. in biology from Harvard University and his Ph.D. in botany from Duke University. John formerly served as the Interim Undersecretary for Science for the Smithsonian Institution, Executive Director of the Association for Tropical Biology and Conservation, and Director of the Consortium for Understanding and Sustaining a Biodiverse Planet, which is one of the four grand challenges of the Smithsonian Institution's strategic plan. He is also Chairman of the Board of the Organization for Tropical Studies (OTS) and an Affiliate Faculty member at George Mason University. He has previously served as an Adjunct Professor at George Washington University and the Chinese Academy of Sciences. Among John's awards and honors are receipt of the Parker-Gentry Award for Biodiversity and Conservation from the Field Museum of Natural History, the Lifetime Achievement Award from Heliconia Society International, and the Edward O. Wilson Biodiversity Technology Pioneer Award for Co-Development of Leafsnap – the First Mobile App for Plant Identification. John is a fellow of the American Association for the Advancement of Science and an honorary Fellow of the Association for Tropical Biology and Conservation. In this interview, he discusses his experiences in life and science.

Aug 28, 202338 min

Ep 722722: Taking Critical Steps to Elucidate Mechanisms of Limb Movement in Locomotion - Dr. Young-Hui Chang

Dr. Young-Hui Chang is a Professor of Biological Sciences at Georgia Institute of Technology where he directs research in the Comparative Neuromechanics Laboratory. Research in Young-Hui's lab aims to examine how the control of movement by the nervous system is influenced by mechanics and physics during locomotion. He is interested in broad mechanisms for behaviors like walking, running, and hopping that apply within and across species. Young-Hui likes to spend his free time with his family. He, his wife, and his two boys enjoy exploring the outdoors, hiking, and camping together. Though Young-Hui was not always a particularly outdoorsy person, enrolling his sons in the Scouts program has provided an avenue for him and his family to learn more and get outside. Young-Hui received his B.S. in Mechanical Engineering and his M.S. in Animal Physiology from Cornell University. Next, he conducted his doctoral studies at the University of California, Berkeley, earning his PhD in Integrative Biology in 2000. Prior to joining the faculty at Georgia Tech, Young-Hui was a postdoctoral researcher at Emory University. While at Emory, he was awarded the Association of Korean Neuroscientists President Outstanding Research Hanwha Award. Young-Hui has also been awarded an NSF CAREER Award. In this interview, he discusses his experiences in life and science.

Aug 21, 202341 min

Ep 721721: Unraveling Mysteries Surrounding the Development and Function of Glial Cells - Dr. Sonia Mayoral

Dr. Sonia Mayoral is the Robert J. and Nancy D. Carney Assistant Professor of Brain Science at Brown University. In the lab, Sonia studies glial cells, the cells in your brain that aren't neurons. These cells perform a lot of different functions and could hold promise for developing therapies for neurologic diseases. Outside of work, Sonia loves spending as much time as possible with her four-year-old son. Lately, they've been enjoying playing Plants vs. Zombies on the iPad and also acting the game out around the house. She received her bachelor's degree in biological sciences from San Jose State University and her PhD in neuroscience from Stanford University. Afterwards, she conducted postdoctoral research at the University of California, San Francisco. She joined the faculty at Brown University in 2021. In this interview, she shares more about her life and science.

Aug 14, 202339 min

Ep 720720: Stimulating Research on the Mechanisms of Memory and Applications of Memory Modulation - Dr. Steve Ramirez

Dr. Steve Ramirez is an Assistant Professor in the Department of Psychological and Brain Sciences at Boston University. In his research, Steve is studying learning and memory, and he is interested in discovering whether it is possible to artificially turn memories on and off. His research focuses on understanding the brain and what we can do when processes in the brain break down. They are working on turning on positive or negative memories in animal models to gain a better understanding of how the brain and memory work. In addition, they use animal models of conditions like depression, anxiety, and PTSD to study whether artificially manipulating memories may alleviate some of the symptoms of these conditions. Steve was born and raised in the Boston area, so accepting a faculty position at Boston University meant reuniting with his family, friends, and beloved New England Patriots. He spends his down time watching Netflix with friends and hanging out with his family. He attended Boston University for his undergraduate studies in neuroscience, was awarded his PhD in Brain and Cognitive Sciences from the Massachusetts Institute of Technology, served as a Visiting Lecturer of Neuroscience at Tufts University while a graduate student, and spent two years at the Center for Brain Science at Harvard University as a Junior Fellow of the Society of Fellows before returning to Boston University as a faculty member. Steve has received many awards and honors thus far in his career, including an NIH Early Independence Award, a NARSAD Young Investigator Award, the Gordon Research Conference Travel Award, the American College of Neuropsychopharmacology Travel Award, Smithsonian Magazine's American Ingenuity Award in the Natural Sciences, the Walle Nauta Award for Continuing Dedication to Teaching at MIT, and the Angus MacDonald Award for Excellence in Undergraduate Teaching at MIT. Steve has also been named among Forbes Magazine's 30 Innovators Under the Age of 30 in the area of Science and Technology, a National Geographic Breakthrough Explorer, one of Science News's Top 10 Bright Young Minds, Pacific Standard Magazine's Top 30 Thinkers Under the Age of 30, and the MIT Technology Review World's Top 35 Innovators Under the Age of 35 Award. He has also given two TED talks. In this interview, Steve talks about his experiences in life and science.

Aug 7, 20231h 8m

Ep 719719: Studying the Sea through Shells, Skeletons, and Sediments - Dr. Abby Smith

Dr. Abby Smith is an Associate Professor and Head of the Department of Marine Science at the University of Otago. In the lab, Abby is dedicated to studying shells and the animals that make shells. She is interested in how shells are made, what they are made out of, and how fast they grow. Abby also examines how shells break down over time and uses old shells to understand what the water was like in the past. Outside of science, Abby is a mother of two, and she keeps busy with family life and taking care of her kids. In her free time, she likes to watch cricket, knit, and cook. In particular, Abby has been experimenting lately with making different fruit jams and preserves. She Received her B.A. Degree in Geology and Biology from Colby College, her M.S. Degree in Earth, Atmospheric, and Planetary Sciences from the Massachusetts Institute of Technology, and her PhD in Earth Science from the University of Waikato. Abby joined us in this interview to share stories from her life and science.

Jul 31, 202339 min

Ep 718718: Making Molecular Movies of Complex Chemical Reactions in Live Cells - Dr. Antoine van Oijen

Dr. Antoine van Oijen is a Distinguished Professor and Australian Research Council Laureate Fellow in the School of Chemistry at the University of Wollongong in Australia. The work Antoine does combines physics, chemistry, and biology. He develops new types of microscopes to visualize complex biochemical reactions at the level of individual molecules. In particular, his group is interested in how DNA is copied before a cell divides. Antoine is also doing research examining how bacteria acquire antibiotic resistance. Antoine and his family enjoy spending much of their free time exploring the beautiful beach and hiking in the wonderful parks nearby. Antoine received his MSc and PhD in Physics from Leiden University in the Netherlands, where his graduate work was recognized with the C.J. Kok prize for best doctoral thesis. Afterwards, he conducted postdoctoral research in Chemistry and Chemical Biology at Harvard University. Antoine served on the faculty at Harvard Medical School and Groningen University in the Netherlands before his recent move to the University of Wollongong where he is today. Antoine has received a wide array of honors and awards for his research, including the Armenise-Harvard Junior Faculty Award, a Searle Scholarship, a NSF CAREER Award, a Vici Award from the Dutch Science Foundation, the Dutch Society for Biochemistry and Molecular Biology Award for the most promising young scientist, and the prestigious Australian Research Council Laureate Fellowship. In this episode, Antoine discusses his research and his journey through life and science.

Jul 24, 202342 min

Ep 717717: Developing Tools and Resources to Accelerate Neuroscience Discovery - Dr. Hongkui Zeng

Dr. Hongkui Zeng is Executive Vice President and Director of the Allen Institute for Brain Science. She is dedicated to understanding how the brain is organized and how the different components of the brain work together to generate behaviors and functions. Hongkui and her colleagues examine the cellular basis of brain circuit formation and how those circuits produce function. They generate foundational tools and resources for the neuroscience community to help scientists around the world advance their research on neurological disease, potential treatments, and more. Living in the beautiful city of Seattle, Hongkui enjoys getting outside and exploring nature. This includes kayaking and hiking in the nearby mountains. When she's at home, Hongkui likes to relax with a good book, listen to music, and indulge in watching shows and movies. She received her B.S. degree in biochemistry from Wuhan University and her PhD in molecular and cell biology from Brandeis University. Next, she conducted postdoctoral research at the Massachusetts Institute of Technology. Hongkui then worked for several years at Omeros Corporation before joining the Allen Institute in 2006. Hongkui has received numerous awards for her work, including the National Academy of Sciences' Pradel Research Award, Gill Transformative Investigator Award from Indiana University, the NIH BRAIN Initiative Cell Census Network Award, and the Award for Scientific Advancement from the Association for Women in Science. She is also an elected member of the National Academy of Sciences. In this interview, Hongkui shares more about her life and science.

Jul 17, 202342 min