NFL Week 4 DraftKings Picks 2025 | Best DFS NFL Lineups, Ownership Projections

NFL is back! In this video, Pat Mayo and Tyler Tamboline (John Breslin of 4for4 DFS Fantasy will return next week) break down the best 2025 NFL Week 4 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, fades, and Underdog Pick’em picks for Week 4. Whether you’re entering GPPs or cash games, this guide has you covered.

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Show Index

00:00 Intro

4:57 Optimal + LV/CHI

27:39 IND/LAR

37:44 NYG/LAC  + BUF/NO

54:56 MINI STACKS

57:22 JAX/SF

1:02:53 NE/CAR

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