Vetenskapens mörker – om pengar och dödliga läkemedel

Vad vet vi egentligen om medicinerna vi stoppar i oss? Alldeles för lite, menar flera ledande experter inom den medicinska forskningen. När vetenskapen brister kan det kosta oss livet.

Lyssna på alla avsnitt i Sveriges Radios app.

Varför kan vi inte längre lita på mycket av det som publiceras i vetenskapliga tidskrifter? Vad är läkemedelföretagens roll? Hur kan man skapa en ny sjukdom? Och vad har antivaccinrörelsen med det här att göra? 

P3 Dystopia letar sig ner bland skandaler, korruption och girighet i läkemedelsvärlden.

Producent och programledare: Viktor Hariz
Programledare: Torill Kornfeldt

Medverkande

• Jill Fisher - docent i socialmedicin, University of North Carolina

• Cory Doctorow - författare och journalist

• Peter Gøtzsche - läkare, gästprofessor vid Universitetet i Newcastle och chef för Institute for Scientific Freedom

• Åsa Nilsonne - psykiatrer, författare och professor emerita i medicinsk psykologi vid Karolinska Institutet

Böcker

• Bad Pharma av Ben Goldacre

• Deadly Medicines and Organised Crime av Peter Gøtzsche 

Ljud och bild

• ABC News Nightline: AIDS (1982)

• Bad Blood (1985)

• A Conversation with Dr. Marcia Angell - HMS Center for Bioethics (2015)

• Mediator: Landmark trial opens in France over antidiabetic pill - Euronews (2019)

• Fake Science - Full Measure (2017)

• Ben Goldacre: What doctors don't know about the drugs they prescribe - TED (2012)

• Sile Lane: The hidden side of clinical trials - TEDx (2016)

• WikiLeaks Cables: Pfizer Targeted Nigerian Attorney General to Undermine Suit - Democracy Now (2010)

• ”60 Minutes”/Washington Post investigation reveals ”revolving door” of drug regulators - CBS Evening News (2017)

• 15 Things You Didn't Know About The Pharmaceutical Industry - Alux.com (2018)

• Viagrareklam

• Opdivoreklam

• Stor korruption i läkemedelshantering - Ekot (2016)

• Marketing to Doctors: Last Week Tonight with John Oliver - HBO (2015)

• Medical Sales Tips: How to Develop Key Opinion Leaders - TheHelpfulDad (2019)

• Orgasm INC. (2009)

• Alan Spanos Oxycontin Commercial

• Oxyana (2013)

• Beth Macy: Big Pharma targeted distressed communities - The Hill (2019)

• Chris Johnson - Opioid epidemic: the medical industry created a public health crisis - TEDx

• Russell Portenoy på Good Morning America - ABC News (2010)

• Oxycontin patients then and now - Milwaukee Journal Sentinel (2012)

• Opioid Wars: Fault Lines - Al Jazeera (2016)

• Opioids: Last Week Tonight with John Oliver - HBO (2016)

• Behind Purdue Pharma’s marketing of OxyContin - PBS Newshour (2019)

• Anti-vaccination activist charged in Samoa amid measles outbreak - Global News (2019)

• Alex Jones: Bayer Admits It Sold HIV Contaminated Blood to Hemophiliacs (2014)

Artiklar

• Pfizer stäms på 50 miljarder kronor (Sveriges Radio, 2007)

• A Blizzard of Prescriptions - Emily Witt (LRB, 2019)

• Whistle-Blowers - Frank Honigsbaum (LRB, 1984)

• Cash for Diagnoses - Gavin Francis (LRB, 2015)

• The Mild Torture Economy - Carl Elliott (LRB, 2010)

• Whose Property? - Paul Taylor (LRB, 2018)

• Vancouver’s Fentanyl Crisis - Anakana Schofield (LRB, 2016)

• Tearing Down The Facade of 'Vitamins Inc.' - David Barboza (NYT, 1999)

• 2 Paths of Bayer Drug in 80's: Riskier One Steered Overseas - Walt Bogdanich and Eric Koli (NYT, 2003)

• The Dark Side of Globalization: Lack of Universal Levodopa Availability - Marcelo Merello (Movement Disorders, 2018)

• PHARMACEUTICAL R&D: What do we get for all that money? -  Donald Light and Joel Lexchin (BMJ, 2012)

• Big pharmaceutical companies are spending far more on marketing than research - Ana Swanson (Washington Post, 2015)

• Hemliga avtal om mediciner - Ebba Blume (Fokus, 2019)

• FIGHTING CORRUPTION IN THE PHARMA SECTOR – WHY WE ALL HAVE A ROLE TO PLAY - Sophie Peresson (Transparency International, 2016)

• An Age-Old Battle: The FDA Versus the Shill - JEREMY GREENE and AARON KESSELHEIM (The Atlantic, 2015)

• Blood Money: Bayer’s Inventory of HIV-Contaminated Blood Products and Third World Hemophiliacs - Leemon McHenry (Accountability in Research, 2014)

• GlaxoSmithKline pays $3bn for illegally marketing depression drug -Stephen Foley (The Independent, 2012)

• When Science Fiction Writers Used Fictional Drugs: Rise and Fall of the Twentieth-Century Drug Dystopia - John Hickman (Utopian Studies, 2009)

• Experter: Måste granskas juridiskt om läkare är jäviga - Jani Pirttisalo Sallinen (SvD, 2016)

• Medtech Giant Pushes Boundaries As Casualties Mount And Sales Soar - SYDNEY P. FREEDBERG and SCILLA ALECCI (ICIJ, 2018)

• Brist på öppenhet om kopplingar mellan läkare och industrin - Ulrika Oredsson (Lunds Universitet, 2018)

• Patientorganisationer riskerar sin trovärdighet när läkemedelsföretag står för notan - Theo Hagman Rogowski (Lunds Universitet, 2019)

• The pioneers of transparency - Iain Chalmers (BMJ, 2015)

• Clinical trials - Regulation EU No 536/2014

• Europe’s academics fail to report results for 90% of clinical trials - Inga Vesper (Nature, 2018)

• Are we facing an opioid crisis in Europe? - Katia M C Verhamme and 
  Arthur M Bohnen (The Lancet, 2019)

• Opioids Threaten to Mess Up Europe, Too - Leonid Bershidsky (Bloomberg, 2019)

• Failing the Public Health — Rofecoxib, Merck, and the FDA - Eric J. Topol (The New England Journal of Medicine, 2004)

• Merck vilseledde läkare om hjärtriskerna med Vioxx - Fredrik Hedlund (Läkemedelsvärlden, 2006)

• Pharma lobbying threatens affordability of medicines in Europe - Olivier Hoedeman (Corporate Europe Observatory, 2019)

• Pfizer Pays $2.3B, but Will It Change the Pharmaceutical Industry? -  RADHA CHITALE (ABC News, 2009)

• Opioid Evangelist Switches Sides in Case Alleging Pharma Abuse - Jef Feeley (Bloomberg, 2019)

• Opioidjätten ansöker om konkurs (SVT Nyheter, 2019)

• Misleading Advertising for Antidepressants in Sweden: A Failure of Pharmaceutical Industry Self-Regulation - Anna V. Zetterqvist,Shai Mulinari (PLOS, 2013)

• EMA to stop ‘revolving doors’ committee members - Ben Adams (Pmlive, 2015)

• Offline: What is medicine’s 5 sigma? - Richard Horton (The Lancet, 2015)

• What the Tamiflu saga tells us about drug trials and big pharma - Ben Goldacre (The Guardian, 2014)

• The Tamiflu fiasco and lessons learnt - Yogendra Kumar Gupta, et.al. (Indian Journal of Pharmacology, 2015)

• New data reveals that Big Pharma is raking in almost half of all the profits in healthcare - Bob Herman (Business Insider, 2019)

• Evidence in Vioxx Suits Shows Intervention by Merck Officials - Alex Berenson (NYT, 2005)

• Contribution of NIH funding to new drug approvals 2010–2016 - Ekaterina Galkina Cleary, et.al (PNAS, 2018)

Musik

• Michael McCann - The Mole

• Nine Inch Nails - 06 Ghosts

• Jesper Kyd - Tension in the nest

• Cliff Martinez - Will she come back?

• Trent Reznor & Atticus Ross - Clue One

• Marcus Bagalà - Boxes: Autumnal Moping

• Paul Leonard Morgan - Anderson's Theme

• Cliff Martinez - Not leaving this circus

• Nine  Inch Nails - 06 Ghosts I

• Cliff Martinez - I'm in the pink

• Calexico - Untitled III - Remix by two lone swordsmen

• Jon Brion - You learn

• Marcus Bagalà - Frets: too too

• Vince Pope - Who are you?

• Vince Pope - Fake

• WOW MOM WOW - Tryptoreal

• Helios - Even today

• Cliff Martinez - I'm sick

• Trent Reznor & Atticus Ross - Empty Places (Reprise)

• Lorn - Unraveled

• Vince Pope - Coming down

• Wojciech Golczewski - Setting up

• Marcus Bagalà - Boxes: It goes like this

• Hans Zimmer - Afraid of time

• Velvet Underground - Heroin