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Midlife Breakdown? It’s a Breakthrough w/ Dr. Mindy Pelz
Episode 143

Midlife Breakdown? It’s a Breakthrough w/ Dr. Mindy Pelz

Over 50 & Flourishing with Dominique Sachse · Dominique Sachse

January 12, 20261h 5m

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Show Notes

In this episode, I sit down with Dr. Mindy Pelz, bestselling author of Age Like a Girl, thought leader, and one of the most trusted voices in women’s health, for a powerful conversation about what really happens to us in midlife. Dr. Mindy isn’t just talking about menopause as a hormonal shift, but as a profound transformation of the brain, body, and identity. From burnout and people-pleasing to leadership and self-trust, this conversation reframes midlife not as a breakdown, but as a breakthrough. This episode is about reclaiming the girl within you, her curiosity, her wisdom, her strength, and learning how to age like a girl with intention, science, and self-compassion.


In this episode, we discuss:

  • Why menopause is a neurological rewiring, not just a drop in estrogen
  • How the loss of estrogen impacts mood, motivation, memory, and identity
  • The “people-pleasing” brain and why women stop caring so much after 50
  • Why midlife burnout is often a signal of transformation, not failure
  • The science behind fasting, ketones, and brain health in postmenopausal women
  • How exercise needs to change in menopause, and why more isn’t always better
  • The role of muscle, creatine, collagen, and movement in aging well
  • Why women are biologically wired for leadership in the second half of life
  • The butterfly metaphor for midlife transformation and becoming who you truly are
  • How to advocate for yourself with doctors and build a healthcare team that listens
  • Why involving partners in the menopause conversation matters more than we think


For more on Dr. Mindy Pelz, follow her on:


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Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.


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