Stacie Pettyjohn: AI Development in Defense and Nuclear Deterrence

In this episode of NucleCast, Adam is joined by Dr. Stacie Pettyjohn, senior fellow and director of the Defense Program at the Center for a New American Security, for a thoughtful discussion on the growing role of artificial intelligence in defense and military operations.

Dr. Pettyjohn explores how AI is increasingly shaping everything from logistics and decision‑making to nuclear command and control, while weighing the potential benefits against the serious risks of integration. The conversation examines AI’s capabilities and limitations, the ethical and strategic challenges it presents, and what its use could mean for nuclear deterrence and autonomous weapons.

She emphasizes the importance of balancing innovation with safety, responsibility, and strategic stability as AI becomes more deeply embedded in modern defense systems.

Stacie Pettyjohn is a senior fellow and director of the Defense Program at the Center for a New American Security. A leading expert on U.S. defense strategy, force planning, airpower, and wargaming, her work focuses on the future of warfare, including artificial intelligence, autonomous systems, drones, and nuclear deterrence in a multipolar world. Previously, she served on the Joint Staff, chaired a Defense Department advisory subcommittee on force integration, and spent more than a decade at RAND Corporation leading major studies and defense wargames. Her work has appeared in Foreign Affairs, The Wall Street Journal, The Washington Post, and other major outlets. She holds a PhD from the University of Virginia.

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