New Books in Medicine

An Organ of Murder: Crime, Violence, and Phrenology in Nineteenth-Century America (Rutgers UP, 2021) explores the origins of both popular and elite theories of criminality in the nineteenth-century United States, focusing in particular on the influence of phrenology. In the United States, phrenology shaped the production of medico-legal knowledge around crime, the treatment of the criminal within prisons and in public discourse, and sociocultural expectations about the causes of crime. The criminal was phrenology’s ideal research and demonstration subject, and the courtroom and the prison were essential spaces for the staging of scientific expertise. In particular, phrenology constructed ways of looking as well as a language for identifying, understanding, and analyzing criminals and their actions. This work traces the long-lasting influence of phrenological visual culture and language in American culture, law, and medicine, as well as the practical uses of phrenology in courts, prisons, and daily life. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived—the other died in agony. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. Alisha Rankin tells their little-known story. At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with “experimental thinking” long before the great experimental boom of the seventeenth century and investigates how competition with lower-class healers spurred on this trend. Alisha Rankin's The Poison Trials: Wonder Drugs, Experiment, and the Battle for Authority in Renaissance Science (U Chicago Press, 2021) sheds welcome and timely light on the intertwined nature of medical innovations, professional rivalries, and political power. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Normally we write blogposts that try to convince you to listen to a conversation with an author about their fascinating book. In the time of COVID-19, it doesn't seem necessary to have to sell you on why you should listen to this podcast. Suffice it to say that Mitchell Hammond’s excellent survey of a dozen deadly diseases is a must-read primer to make sense of epidemic history. In Epidemics and the Modern World (University of Toronto Press, 2020), he balances the science of disease etiology and disease cycles with political, socio-economic, and cultural contexts. Read this book! Mitchell L. Hammond, an Assistant Professor at the University of Victoria in beautiful British Columbia. Dr. Hammond studied at Yale, where he earned a BA in Political Science and a MA in Religious History before getting another MA and a PhD in European History at the University of Virginia. His dissertation was entitled “The Origins of Civic Health Care in Early Modern Germany”. He has published several articles and book chapters on the intersection of medicine and religion in 16th and 17th century Germany. Michael G. Vann is a professor of world history at California State University, Sacramento. A specialist in imperialism and the Cold War in Southeast Asia, he is the author of The Great Hanoi Rat Hunt: Empires, Disease, and Modernity in French Colonial Vietnam (Oxford University Press, 2018). When he’s not reading or talking about new books with smart people, Mike can be found surfing in Santa Cruz, California. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Scientists have scientific reason and use the scientific method. Humanists have... Emotion? Close reading? Not so, argues Eric Hayot in Humanist Reason: A History. An Argument. A Plan (Columbia UP, 2021). Contrary to popular belief, the humanities involve both reasoning and methods. Humanist reason, Hayot shows, is philosophically and historically grounded and applicable to almost every discipline. Part history of philosophy, part methods handbook, and part manifesto, Humanist Reason will change the way we advocate for the humanities in the twenty-first century. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Life expectancy in the United States has recently fallen for three years in a row—a reversal not seen since 1918 or in any other wealthy nation in modern times. In the past two decades, deaths of despair from suicide, drug overdose, and alcoholism have risen dramatically, and now claim hundreds of thousands of American lives each year—and they’re still rising. Anne Case and Angus Deaton, known for first sounding the alarm about deaths of despair, explain the overwhelming surge in these deaths and shed light on the social and economic forces that are making life harder for the working class. They demonstrate why, for those who used to prosper in America, capitalism is no longer delivering. Deaths of Despair and the Future of Capitalism (Princeton University Press, 2020) paints a troubling portrait of the American dream in decline. For the white working class, today’s America has become a land of broken families and few prospects. As the college educated become healthier and wealthier, adults without a degree are literally dying from pain and despair. In this critically important book, Case and Deaton tie the crisis to the weakening position of labor, the growing power of corporations, and, above all, to a rapacious health-care sector that redistributes working-class wages into the pockets of the wealthy. Capitalism, which over two centuries lifted countless people out of poverty, is now destroying the lives of blue-collar America. This book charts a way forward, providing solutions that can rein in capitalism’s excesses and make it work for everyone. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Mao Zedong’s Great Leap Forward campaign organized millions of Chinese peasants into communes in a misguided attempt to rapidly collectivize agriculture with disastrous effects. Catastrophic famine lingered as the global cholera pandemic of the early 1960s spread rampantly through the infected waters of southeastern coastal China. Confronted with a political crisis and the seventh global cholera pandemic in recorded history, the communist government committed to social restructuring in order to affirm its legitimacy and prevent transmission of the disease. Focusing on the Wenzhou Prefecture in Zhejiang Province, the area most seriously stricken by cholera at the time, Xiaoping Fang demonstrates how China’s pandemic was far more than a health incident; it became a significant social and political influence during a dramatic transition for the People’s Republic. China's Cholera Pandemic: Restructuring Society Under Mao (University of Pittsburgh Press, 2021) reveals how disease control and prevention, executed through the government’s large-scale, clandestine anticholera campaign, were integral components of its restructuring initiatives, aimed at restoring social order. The subsequent rise of an emergency disciplinary health state furthered these aims through quarantine and isolation, which profoundly impacted the social epidemiology of the region, dividing Chinese society and reinforcing hierarchies according to place, gender, and socioeconomic status. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In his book The Next Shift: The Fall of Industry and the Rise of Healthcare in Rust Belt America (Harvard University Press, 2021), Gabriel Winant explains how the social reproductive labor sustaining the US's industrial economy was institutionalized in response to steelworker layoffs, aging, and sickness beginning in the 1960s. The result was a recomposition of the American working class, from a predominantly white male industrial one, to a meagerly paid and socially devalued pool of care workers comprised mostly of women, and especially women of color. Neoliberalism's insecure labor regime is not a reversion to an earlier period of inequality but a consequence of midcentury welfare policy, the partial security it offered and the race and gender hierarchies it remade. Patrick Reilly studies history at Vanderbilt University Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Of all forms of alternative medicine, chiropractic is the one that is most generally accepted. In the UK, for instance, chiropractors are regulated by statute and even have their own ‘Royal College of Chiropractic’. In the US, chiropractic’s country of origin, most chiropractors carry the title ‘doctor’ and many consumers believe they are medically trained. Despite this high level of acceptance, chiropractic is wide open to criticism. The claims and assumptions made by chiropractors are far from evidence based. Chiropractic manipulations are of doubtful effectiveness and have regularly been associated with severe adverse effects, including multiple fatalities. The advice issued by chiropractors to patients and consumers is often less than responsible. The behaviour of chiropractors and their organisations is frequently less than professional. Edzard Ernst's Chiropractic:' Not All That It's Cracked Up to Be (Springer, 2020) presents and discusses recent evidence in and around chiropractic in a factual and unemotional manner. It amounts to an evidence-based critique of this profession and discloses the often dangerously misleading information published for the lay audience. It thereby contributes to advancing public health and critical thinking. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

John M. Janzen's Health in a Fragile State: Science, Sorcery, and Spirit in the Lower Congo (Wisconsin University Press, 2019) offers a granular and insightful view of the state of healthcare services in the Manianga region of the Lower Congo (Democratic Republic of Congo), and examines the extent to which said services are able to improve the health of the communities that inhabit this region. The collapse of the Congolese state during the 1980s and 1990s resulted in the deterioration and virtual disappearance of state-sponsored healthcare institutions. This vacuum came to be filled by organisms such as the World Health Organization, other NGOs and health-based institutions organized under the new framework of the health zone. As a result, a precarious healthcare system emerged, one that combines the ingenuity and resources of the local population with those from external sources. Unfortunately, this system is only able to offer a limited and fragile solution to the health needs of the populations it seeks to serve. Janzen uses this examination to remind us that positive health outcomes are not merely a factor of adequate knowledge and resources, but also require that those in charge of creating and implementing health policies are seen as legitimate within their communities. To support this argument, he starts by describing the population history of the region in relation to policies of the colonial and postcolonial era, and the ways in which specific diseases affected the lives peoples in the region. He then explores the different kind of institutions that support the social reproduction of health and the ways in which people in this region explain what it means to be healthy. Finally, he looks at theories of legitimation, both in Western thought and in the Kongo culture, and argues that legitimacy is a key element in the creation of a robust and effective healthcare system. Esperanza Brizuela-Garcia is an associate professor of history at Montclair State University. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine: Exposing the Crisis of Credibility in Clinical Research (Wakefield Press, 2020) provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine. Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown. Mind Thief: The Story of Alzheimer's (Columbia UP, 2021) is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Welcome to The Academic Life. You are smart and capable, but you aren’t an island, and neither are we. So we reached across our mentor network to bring you podcasts on everything from how to finish that project, to how to take care of your beautiful mind. Wish we’d bring in an expert about something? Email us at [email protected] or [email protected]. Find us on Twitter: The Academic Life @AcademicLifeNBN. In this episode you’ll hear: about Dr Bikman’s unconventional path to pursuing degrees in science, why scientists need to do a postdoc, what it means to have your own lab, the important role of insulin in the body, and a discussion of the book Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease--And How to Fight It (Benbella Books, 2020). Our guest is: Dr. Benjamin Bikman, associate professor of Physiology & Developmental Biology at BYU, where he has his own lab and is currently exploring the contrasting roles of insulin and ketones as key drivers of metabolic function. He frequently publishes his research in peer-reviewed journals and presents at international science meetings. He lives in Utah with his wife and children, and strongly believes in the importance of a work-life balance. Your host is: Dr. Christina Gessler, a historian of women, gender, and sexuality. She specializes in decoding diaries written by rural women in 19th-century America. She supports her work-life balance by taking long walks, and making time for her loved ones. Listeners to this episode might be interested in: Why We Get Sick by Benjamin Bikman Big Fat Surprise by Nina Teicholz Getting the Most Out of Your Postdoc Determine Whether A STEM Major Is The Right Choice Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Viruses are not very different from machines that process information, and thus, how the virus functions can be simulated on a computer. This ability to “imitate” the way viruses behave is particularly useful today, as we battle the impact of the coronavirus pandemic and struggle to prepare for similar events. Dr. Klaus Mainzer, Co-founder and Senior Professor at the Carl Friedrich von Weizsäcker Center of the University of Tübingen and President of European Academy of Sciences and Arts in Salzburg, explains this further in a new podcast episode, in which he talks about his book Leben als Maschine: Wie entschlüsseln wir den Corona-Kode? published by Brill. He explains how bringing together the fields of bioinformatics, machine learning, AI, and big data can help us to decipher the workings of the novel coronavirus and, perhaps, be better equipped to deal with such crises in the future. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Based on a viral article, the gripping medical mystery story of Ron Davis, a world-class Stanford geneticist who has put his career on the line to find the cure for chronic fatigue syndrome, the disease killing his son. For the past six years, Whitney Dafoe has been confined to a bedroom in the back of his parents' home, unable to walk, to eat, to speak. The sound of music causes him pain. At one point, the formerly healthy, young, freelance photographer, faced starvation as his 6'3" frame withered to 115 pounds. In desperation, Whitney and his parents went from one specialist to another, and still no answers. Then, finally, a diagnosis: the mysterious disease myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS). Whitney's story is heartbreaking, but it's also one of redemption. It reaches far beyond just one family's harrowing tale. Today, ME/CFS affects between 1 and 2.5 million Americans--and 20 million people around the world. Those afflicted largely suffer in silence because the disease is little known and much misunderstood. The question lingers still whether it even exists outside the patient's mind. Often disbelieved, they're abandoned by family and friends. They lose their jobs, and battle with insurance companies over rising medical costs as the chronic disease continues on year after year. In one way, Whitney has been lucky. He could reach out to his father, a world renowned, scientist, for answers. This book is the story of one father's desperate hunt for the insidious illness that stole his son away. The Puzzle Solver follows Ron as he unravels the molecular trail within his own son's donated blood and genome, to began to find answers. He confirms this is a biological disease and uncovers new possibilities for treatments and potentially a cure. At its heart, The Puzzle Solver: A Scientist's Desperate Hunt to Cure the Illness That Stole His Son by Tracie White and Ronald W. Davis (Hachette Books, 2021) is about more than just cutting edge research or a race to find the cure for ME/CFS--it's about the unbreakable bond between a father and his son, and the lengths to which a parent will go to save their child's life. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Although physicians during World War I, and scholars since, have addressed the idea of disorders such as shell shock as inchoate flights into sickness by men unwilling to cope with war's privations, they have given little attention to the agency many soldiers actually possessed to express dissent in a system that medicalized it. In Germany, these men were called "war tremblers," for their telltale symptom of uncontrollable shaking. Based on archival research that constitutes the largest study of psychiatric patient files from 1914 to 1918, Rebecca Ayako Bennette examines the important space that wartime psychiatry provided soldiers expressing objection to the war in Diagnosing Dissent: Hysterics, Deserters, and Conscientious Objectors in Germany during World War One (Cornell University Press, 2020). Michael E. O’Sullivan is Professor of History at Marist College where he teaches courses about Modern Europe. He published Disruptive Power: Catholic Women, Miracles, and Politics in Modern Germany, 1918-1965 with University of Toronto Press in 2018. It was recently awarded the Waterloo Centre for German Studies Book Prize for 2018. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Can your zip code predict when you will die? Should you space out childhood vaccines? Does talcum powder cause cancer? Why do some doctors recommend e-cigarettes while other doctors recommend you stay away from them? Health information―and misinformation―is all around us, and it can be hard to separate the two. A long history of unethical medical experiments and medical mistakes, along with a host of celebrities spewing anti-science beliefs, has left many wary of science and the scientists who say they should be trusted. How can we unravel the knots of fact and fiction to find out what we should really be concerned about, and what we can laugh off? In Viral BS: Medical Myths and Why We Fall for Them (Johns Hopkins UP, 2021), medical journalist, doctor, professor, and former CDC disease detective Seema Yasmin, driven by a need to set the record straight, dissects some of the most widely circulating medical myths and pseudoscience. Exploring how epidemics of misinformation and disinformation can spread faster than microbes, Dr. Yasmin asks why bad science is sometimes more believable and contagious than the facts. Each easy-to-read chapter covers a specific myth, whether it has endured for many years or hit the headlines more recently. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Typhoid fever is a food- and water-borne infectious disease that was insidious and omnipresent in Victorian Britain. It was one of the most prolific diseases of the Industrial Revolution. There was a palpable public anxiety about the disease in the Victorian era, no doubt fueled by media coverage of major outbreaks across the nation, but also because Queen Victoria's husband, Prince Albert, died of the disease in 1861. Their son and heir, Prince Albert Edward, contracted and nearly succumbed to typhoid a decade later in 1871. The Filth Disease: Typhoid Fever and the Practices of Epidemiology in Victorian England (U Rochester Press, 2020) shows that typhoid was at the center of a number of critical debates about health, science, and governance. Victorian public health reformers, the book argues, working in central and local government, framed typhoid as the most pressing public health problem in order to persuade local officials to implement sanitary infrastructure to prevent the spread of disease. In this period British epidemiologists uncovered how typhoid is spread via food and water supplies, disrupting the longstanding idea that typhoid was spread via filth. In the process the modern disciple of epidemiology emerged as the chief science of public health. Typhoid was as much a social and political problem as it was a scientific one, and The Filth Disease provides a striking reminder of the cultural context in which infectious diseases strike populations and how scientists study them. Jacob Steere-Williams is Associate Professor of History at the College of Charleston. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Much of the world's politics revolve around questions about the development of the international market for drugs; the roles merchants, government officials, and drug manufacturers played in shaping this market over time and space; and the process of globalization. There are no easy answers to these questions, but the decisions that all of us make about them will have tremendous consequences for individuals and for the planet in the future. Kenneth V. Faunce's new book Heavy Traffic: The Global Drug Trade in Historical Perspective (Oxford UP, 2020) helps students to understand globalization not as an inevitable or natural process, but instead as one that is created by and responds to a variety of human motivations. Examining the international trade in coffee, alcohol, opium, heroin, and cocaine, which have had a significant impact on economies and societies in countries around the world, it offers insight into globalization as a historical process, thereby helping to make sense of today's interconnected world, where products grown or produced in only a handful of places circulate widely, with varying impacts on local populations. Lucas Richert is an associate professor in the School of Pharmacy at the University of Wisconsin, Madison. He studies intoxicating substances and the pharmaceutical industry. He also examines the history of mental health. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Today we speak to Hannah Marcus, Assistant Professor in the Department of the History of Science at Harvard University in Cambridge, Massachusetts, about her new monograph, Forbidden Knowledge: Medicine, Science, and Censorship in Early Modern Italy (University of Chicago Press, 2020). Forbidden Knowledge explores the censorship of medical books from their proliferation in print through the prohibitions placed on them during the Counter-Reformation. How and why did books banned in Italy in the sixteenth century end up back on library shelves in the seventeenth? Historian Hannah Marcus uncovers how early modern physicians evaluated the utility of banned books and facilitated their continued circulation in conversation with Catholic authorities. Through extensive archival research, Marcus highlights how talk of scientific utility, once thought to have begun during the Scientific Revolution, in fact began earlier, emerging from ecclesiastical censorship and the desire to continue to use banned medical books. What’s more, this censorship in medicine, which preceded the Copernican debate in astronomy by sixty years, has had a lasting impact on how we talk about new and controversial developments in scientific knowledge. Beautiful illustrations accompany this masterful, timely book about the interplay between efforts at intellectual control and the utility of knowledge. Jana Byars is the Academic Director of Netherlands: International Perspectives on Sexuality and Gender. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In today’s program, Dr. Paul Steinberg, a psychiatrist and clinical professor at the University of British Columbia, discusses his recently released book Psychoanalysis in Medicine: Applying Psychoanalytic Thought to Contemporary Medical Care (Routledge, 2020). In this new volume, Dr. Steinberg offers both theoretical inferences and practical guidance related to the application of psychoanalysis to medical practice. Dr. Steinberg provides insight on, among many other topics, how clinicians’ awareness of their own feelings can aid in the diagnostic process and how a psychoanalytic approach can enrich patient interview. Alec Kacew is a medical school student at the University of Chicago. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Daniel A. Rodriguez's history of a newly independent Cuba shaking off the U.S. occupation, The Right to Live in Health: Medical Politics in Postindependence Havana (University of North Carolina Press, 2020), focuses on the intersection of public health and politics in Havana. While medical policies were often used to further American colonial power, in Cuba, Rodriguez argues, they evolved into important expressions of anticolonial nationalism as Cuba struggled to establish itself as a modern state. A younger generation of Cuban medical reformers, including physicians, patients, and officials, imagined disease as a kind of remnant of colonial rule. These new medical nationalists, as Rodriguez calls them, looked to medical science to guide Cuba toward what they envisioned as a healthy and independent future. Rodriguez describes how medicine and new public health projects infused republican Cuba's statecraft, powerfully shaping the lives of Havana's residents. He underscores how various stakeholders, including women and people of color, demanded robust government investment in quality medical care for all Cubans, a central national value that continues today. On a broader level, Rodriguez proposes that Latin America, at least as much as the United States and Europe, was an engine for the articulation of citizens' rights, including the right to health care, in the twentieth century. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer’s disease, and Parkinson’s disease. Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In his book The Future of Brain Repair: A Realist's Guide to Stem Cell Therapy (MIT Press, 2020), neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer’s disease, Parkinson’s disease, and spinal cord injuries. Certainly brain disorders are in need of effective treatments. These disorders don’t just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells—and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson’s and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body. New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair? You can find more about Jack’s work here and here. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Vaccines make us wholly or partly immune to disease, such as Covid-19. But what is it to be immune? What is an immune system, and what does it do? In its beginnings, immunology was considered the science of the self/non-self distinction: the immune system comprised the self’s defenses against invading non-self pathogens, and was a sophisticated system possessed only by vertebrates. In Philosophy of Immunology (Cambridge University Press, 2020), Thomas Pradeu explains why these traditional conceptions have been upended over the past 20 years or so. It is now accepted that even single celled organisms have immune systems and that immune systems are also active in many biological activities, including regulation of foreign entities that are not part of the body but are not pathogens either, such as the gut microbiome. Pradeu, who is senior researcher at CNRS and University of Bordeau, defends his view of the individual as an immunologically unified chimera, and speculates about the implications for our understanding of cognition and psychiatric illness in the light of new discoveries of overlap between the immune and nervous systems. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

We are just over a year from when global news first reported a new type of pneumonia emerging in the Chinese city of Wuhan. A lockdown of Wuhan on January 23rd, 2020, was the first indication that these stories were more serious than originally thought. All of us know what happened next: COVID-19 spread from China to other countries in Asia, then to Europe, then to North America, then worldwide. To slow the spread, countries frantically imposed travel restrictions on those coming from places affected by COVID-19: a massive shift away from the increasingly open borders seen over the past two decades. One traveller caught up in these new restrictions was Ethan Lou, author of Field Notes From a Pandemic: A Journey Through a World Suspended (Signal, 2020). Ethan arrives in China in early 2020 to visit his family, as the first leg of a trip around the world. On each leg of his journey, he sees how different parts of the world are transformed by the global pandemic. Field Notes From a Pandemic, named among the CBC’s best Canadian non-fiction books of 2020, is one half travelogue, one half commentary, in and about a changed world. In this interview, Ethan and I talk about his journey around the world, and how COVID-19 made a routine trip exceptionally complicated. He shares how he saw the world change in real-time, and which of those changes may end up sticking around. Ethan Lou is a former Reuters reporter and has served as a visiting journalist at the University of British Columbia. His writing has appeared in the Guardian, the Globe and Mail, Maclean's, the South China Morning Post, the Walrus, and the Washington Post. His next book is Once a Bitcoin Miner: Scandal and Turmoil in the Cryptocurrency Wild West. He can be found on Twitter at @Ethan_Lou, and his work can be found at https://ethanlou.com/. You can find more reviews, excerpts, interviews, and essays at The Asian Review of Books, including its review of Field Notes From a Pandemic. Follow on Facebook or on Twitter at @BookReviewsAsia. Nicholas Gordon is a reviewer for the Asian Review of Books. In his day job, he’s a researcher and writer for a think tank in economic and sustainable development. He is also a print and broadcast commentator on local and regional politics. He can be found on Twitter at @nickrigordon. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In the early 1970s, a new wave of public service announcements urged parents to help end an American tradition of child abuse. The message, relayed repeatedly over television and radio, urged abusive parents to seek help. Support groups for parents, including Parents Anonymous, proliferated across the country to deal with the seemingly burgeoning crisis. At the same time, an ever-increasing number of abused children were reported to child welfare agencies, due in part to an expansion of mandatory reporting laws and the creation of reporting hotlines across the nation. In Abusive Policies: How the American Child Welfare System Lost Its Way (University of North Carolina Press Books, 2020), Mical Raz examines this history of child abuse policy and charts how it changed since the late 1960s, specifically taking into account the frequency with which agencies removed African American children from their homes and placed them in foster care. Highlighting the rise of Parents Anonymous and connecting their activism to the sexual abuse moral panic that swept the country in the 1980s, Raz argues that these panics and policies--as well as biased viewpoints regarding race, class, and gender--played a powerful role shaping perceptions of child abuse. These perceptions were often directly at odds with the available data and disproportionately targeted poor African American families above others. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Medicine and Memory in Tibet: Amchi Physicians in an Age of Reform (University of Washington Press, 2018) is the first full-length ethnography of Tibetan medical practitioners (amchi) in central Tibet working outside of major Tibetan medical institutions in Lhasa. Departing from extant ethnographies and scholarship on Tibetan medicine in the twentieth-century that often focus on institutions such as the Mentsikhang, Tibetan Medical College, and TAR Tibetan Pharmaceutical Factory, Theresia Hofer follows and traces the medical work of local Tibetan doctors in rural settings in Tsang and in Shigatse Town. By centering on amchis who were not part of the Tibetan state-sponsored medical structures that were incorporated into the PRC socialist health care system in the 1950s, Hofer reveals perspectives and experiences that have been overlooked in national and institutional narratives. Drawing on literature addressing Tibetan amchis' memory and oral history in socialist and postsocialist contexts, Hofer also inquires into the social and political dynamics that influence memory and history-making, especially with regard to the violent past. Medicine and Memory in Tibet also consistently considers gender and aims to tackle the lack of understanding of gender in Tibetan medicine in the twentieth century. The perspectives of the amchis allow the inclusion of more women in the study of Tibetan medicine and uncover different subaltern histories of the Tibetan experience. Medicine and Memory in Tibet demonstrates that amchis outside of major state-sponsored institutions have continued to contribute significantly to the survival and revival of Tibetan medicine and culture into the present day. Through the amchis' negotiations and agency within the new regime since the 1950s, Tibetan medicine was able to not only become an important health care resource for Tibetans and the state into the 1990s, it also became a stronghold for the preservation and revival of other aspects of Tibetan culture, language, and the local economy in contemporary China. Daigengna Duoer is a Ph.D. student at the Religious Studies Department, University of California, Santa Barbara. Her dissertation is a digital humanities project mapping transnational and transregional Buddhist networks connecting twentieth-century Inner Mongolia, Manchuria, Republican China, Tibet, and the Japanese Empire. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

A reporter uncovers the secrets behind the scientific scam of the century. The news breaks first as a tale of fear and pity. Doctors at a London hospital claim a link between autism and a vaccine given to millions of children: MMR. Young parents are terrified. Immunization rates slump. And as a worldwide ‘anti-vax’ movement kicks off, old diseases return to sicken and kill. But a veteran reporter isn’t so sure, and sets out on an epic investigation. Battling establishment cover-ups, smear campaigns, and gagging lawsuits, he exposes rigged research and secret schemes, the heartbreaking plight of families struggling with disability, and the scientific deception of our time. Brian Deer's The Doctor Who Fooled the World: Andrew Wakefield's War on Vaccines (Johns Hopkins UP, 2020) tells the troubling story of Andrew Wakefield: a man in search of greatness, who stakes his soul on big ideas that, if right, might transform lives. But when the facts don’t fit, he can’t face failure. He’ll do whatever it takes to succeed. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In Electric Brain: How the New Science of Brainwaves Reads Minds, Tells Us How We Learn, and Helps Us Change for the Better (BenBella, 2020), eminent neuroscientist R. Douglas Fields surveys the history and current state of scientific understanding about the brain as an electrical organ, and how the electrical activity of the brain relates to cognitive functioning and various clinical conditions. The book begins by documenting some of the fascinating and obscure history of the discovery and early science of electrical brain activity measurements, or ‘brainwaves’. It then goes on to summarize the latest cutting edge research on brainwaves in a wide variety of basic and applied areas of science and medicine - including neuroimaging, neuroplasticity, brain-machine interfaces, artificial intelligence, neurofeedback, brain stimulation therapies, and many others. Electric Brain is a highly accessible, but fact-filled and up-to-date, treatment of one of the most central - and yet still so enigmatic - topics in all of modern science. Dr. R Douglas Fields is Chief of the Nervous System Development and Plasticity Section at the United States National Institutes of Health. He is a world expert on neuron-glia interactions and cellular mechanisms of memory, and is particularly well known for his work on white matter plasticity. Dr. John Griffiths (@neurodidact) is an Assistant Professor at the University of Toronto, and Head of Whole Brain Modelling at the CAMH Krembil Centre for Neuroinformatics. His research group (grifflab.com) works at the intersection of computational neuroscience and neuroimaging, building simulations of human brain activity aimed at improving the understanding and treatment of neuropsychiatric and neurological illness. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Americans today are often skeptical of scientific authority. Many conservatives dismiss climate change and Darwinism as liberal fictions, arguing that "tenured radicals" have coopted the sciences and other disciplines. Some progressives, especially in the universities, worry that science's celebration of objectivity and neutrality masks its attachment to Eurocentric and patriarchal values. As we grapple with the implications of climate change and revolutions in fields from biotechnology to robotics to computing, it is crucial to understand how scientific authority functions--and where it has run up against political and cultural barriers. Science Under Fire: Challenges to Scientific Authority in Modern America (Harvard UP, 2020) reconstructs a century of battles over the cultural implications of science in the United States. Andrew Jewett reveals a persistent current of criticism which maintains that scientists have injected faulty social philosophies into the nation's bloodstream under the cover of neutrality. This charge of corruption has taken many forms and appeared among critics with a wide range of social, political, and theological views, but common to all is the argument that an ideologically compromised science has produced an array of social ills. Jewett shows that this suspicion of science has been a major force in American politics and culture by tracking its development, varied expressions, and potent consequences since the 1920s. Looking at today's battles over science, Jewett argues that citizens and leaders must steer a course between, on the one hand, the naïve image of science as a pristine, value-neutral form of knowledge, and, on the other, the assumption that scientists' claims are merely ideologies masquerading as truths. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Today I talked to Chris Hamby about his book Soul Full of Coal Dust: The True Story of an Epic Battle for Justice (Little Brown, 2020). Hamby looks into why there has been a surge in black-lung disease in West Virginia and elsewhere in recent years. Poor self-policing and rapacious business practices go a long way in explaining the upsurge. Add in a tradition of fatalism caused by King Coal, and it becomes a minor miracle –but a miracle all the same—that some miners have been able to secure a measure of justice. Chris Hamby is an investigative reporter for the New York Times. He won the Pulitzer Prize for Investigative Journalism in 2014 and was a finalist for the Pulitzer Prize in International Reporting in 2017. Dan Hill, PhD, is the author of eight books and leads Sensory Logic, Inc. (https://www.sensorylogic.com). To check out his related “Dan Hill’s EQ Spotlight” blog, visit https://emotionswizard.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Today, more than 200,000 men and women over age fifty are languishing in prisons around the United States. It is projected that by 2030, one-third of all incarcerated individuals will be older adults. An already overcrowded and underserved prison system is straining to manage the needs of incarcerated older adults with growing frailty and health concerns. Separated from their families and communities despite a low risk of recidivism, incarcerated older adults represent a major social-justice issue that reveals the intersectional factors at play in their imprisonment. How do the people aging in prison understand their life experiences? In Aging Behind Prison Walls, Tina Maschi and Keith Morgen offer a data-driven and compassionate analysis of the lives of incarcerated older people. They explore the transferable resiliencies and coping strategies used by incarcerated aging adults to make meaning of their lives before, during, and after imprisonment. The book draws on extensive quantitative and qualitative research as well as national datasets. It features rich narrative case studies that present stories of trauma, coping, and well-being. Based on the data, Maschi and Morgen present a solution-focused caring-justice framework in order to understand and transform the individual- and community-level structural factors that have led to and perpetuate the aging-in-prison crisis. They offer concrete proposals--at the community and national policy levels--to address the pressing issues of incarcerated elders. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

The COVID-19 pandemic has affected every country around the world in a manner not seen since the Great Financial Crisis of 2008, and is perhaps one of the most transformative events in decades. Most countries and governments have played catch-up to the pandemic, trying to get a handle on case numbers after an explosive increase. But a few places: Taiwan, Singapore, Hong Kong, South Korea, New Zealand, Australia, Vietnam and China appear to have kept the virus largely under control. Confronting COVID-19: A Strategic Playbook for Leaders and Decision Makers (Marshall Cavendish International Asia, 2020) by Devadas Krishnadas is one of the first attempts to seriously study the public responses to the COVID-19 pandemic, as well as plot out some of the possible economic, geopolitical and social changes that may arise. More information on the book can be found on its official microsite. In this interview, Mr. Devadas and I talk about what policies worked to control COVID, how the region will develop, and how business and social operations might change as a result of the pandemic. We also talk about how recent events since the book’s publication affect its conclusions. Devadas Krishnadas is CEO of the Future-Moves Group, with more than 20 years of experience in the public and private sectors. He previously held senior positions in the Singapore government, such as in the Prime Minister's Office, Ministry of Finance, Ministry of Community Development, Youth and Sports, and Ministry of Home Affairs. “Confronting COVID-19” is his fifth book. You can find more reviews, excerpts, interviews, and essays at The Asian Review of Books, including its review of Confronting COVID-19. Follow on Facebook or on Twitter at @BookReviewsAsia. Nicholas Gordon is a reviewer for the Asian Review of Books. In his day job, he’s a researcher and writer for a think tank in economic and sustainable development. He is also a print and broadcast commentator on local and regional politics. He can be found on Twitter at @nickrigordon. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

We live in an age of moral revolutions in which the once morally outrageous has become morally acceptable, and the formerly acceptable is now regarded as reprehensible. Attitudes toward same-sex love, for example, and the proper role of women, have undergone paradigm shifts over the last several decades. In this book, Robert Baker argues that these inversions are the product of moral revolutions that follow a pattern similar to that of the scientific revolutions analyzed by Thomas Kuhn in his influential book, The Structure of Moral Revolutions: Studies of Changes in the Morality of Abortion, Death, and the Bioethics Revolution (MIT Press, 2019). After laying out the theoretical terrain, Baker develops his argument with examples of moral reversals from the recent and distant past. He describes the revolution, led by the utilitarian philosopher Jeremy Bentham, that transformed the postmortem dissection of human bodies from punitive desecration to civic virtue; the criminalization of abortion in the nineteenth century and its decriminalization in the twentieth century; and the invention of a new bioethics paradigm in the 1970s and 1980s, supporting a patient-led rebellion against medical paternalism. Finally, Baker reflects on moral relativism, arguing that the acceptance of "absolute" moral truths denies us the diversity of moral perspectives that permit us to alter our morality in response to changing environments. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

When is sorrow sickness? That is the question that this book asks, exploring how our understandings of sadness, melancholy, depression, mania and anxiety have changed over time, and how societies have tried to treat something which lies on the border between the natural and the pathological. Jonathan Sadowsky's book The Empire of Depression: A New History (Polity, 2020) explores the various medical treatments for depression, classed as a modern illness with definite (but changing) symptoms from the 20th century onwards, in relation to a longer history of treatments for ‘melancholia’ and related states considered either as biological or social sicknesses or as a natural part of some people’s constitution. He also compares the western history of medicalising depression with the experiences of both sadness and clinical depression in non-western cultures, such as Nigeria and Japan. He asks, what have we lost as a consequence of the hegemony of the western clinical model, and how can we reclaim the patient experience in the face of sometimes hostile doctors and pharmaceutical companies? The book is poetic but well-researched, written by a leading medical historian, and distinguished from the crowd of books about depression through its global focus, and its historical rigour. C.J. Valasek is a Ph.D. Candidate in Sociology & Science Studies at the University of California San Diego. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Between 1927 and 1979, more than 8,000 people were involuntarily sterilized in five hospitals across the state of Virginia. From this plain and terrible fact springs Elizabeth Catte's Pure America: Eugenics and the Making of Modern Virginia (Belt, 2021), a sweeping, unsparing history of eugenics in Virginia, and by extension the United States. Virginia's twentieth-century eugenics program was not the misguided initiative of well-meaning men of the day, writes Catte, with clarity and ferocity. It was a manifestation of white supremacy. It was a form of employment insurance. It was a means of controlling "troublesome" women and a philosophy that helped remove poor people from valuable land. It was cruel and it was wrong, and yet today sites where it was practiced like Western State Hospital, in Staunton, VA, are rehabilitated as luxury housing, their histories hushed up in the service of capital. As was amply evidenced by her acclaimed 2018 book What You Are Getting Wrong About Appalachia, Catte has no room for excuses; no patience for equivocation. What does it mean for modern America, she asks here, that such buildings are given the second chance that 8,000 citizens never got? And what possible interventions can be made now, repair their damage? Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In Diagnosing Desire: Biopolitics and Femininity into the Twenty-First Century, (The Ohio State University Press, 2020), Alyson K. Spurgas, Ph.D. examines the “new science of female sexuality” from a critical, sociological perspective, considering how today’s feminist-identified sex researchers study and manage women with low desire. Diagnosing Desire investigates experimental sex research that measures the disconnect between subjective and genital female arousal, contemporary psychiatric diagnoses for low female desire, new models for understanding women’s sexual response, and cutting-edge treatments for low desire in women—including from the realms of mindfulness and alternative healing. Spurgas makes the case that, together, all of these technologies create a “feminized responsive desire framework” for understanding women’s sexuality, and that this, in fact, produces women’s sexuality as a complex problem to be solved. The biggest problem, Spurgas argues, is that gendered and sexualized trauma—including as it is produced within techno-scientific medicine itself—is too often ignored in contemporary renderings. Through incisive textual analysis and in-depth qualitative research based on interviews with women with low desire, Spurgas argues for a more radical and communal form of care for feminized—and traumatized—populations, in opposition to biopolitical mandates to individualize and neo-liberalize forms of self-care. Ultimately, this is a book not just about a specific diagnosis or dysfunction but about the material-discursive regimes that produce and regulate femininity. Michael O. Johnston, Ph.D. is an Assistant Professor of Sociology at William Penn University. His most recent study, “The Queen and Her Royal Court: A Content Analysis of Doing Gender at a Tulip Queen Pageant”, was published in Gender Issues Journal. His interests include the sociology of art and culture, sociology of death and dying, and sociology of sex and gender. More can be found about Michael O. Johnston, Ph.D. by going to his website, Google Scholar, following him on Twitter @ProfessorJohnst, or emailing him at johnstonmo at wmpenn dot edu. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In The Mutant Project: Inside the Global Race to Genetically Modify Humans (St. Martin's Press, 2020), anthropologist Eben Kirksey visits the frontiers of genetics, medicine, and technology to ask: Whose values are guiding gene editing experiments? And what does this new era of scientific inquiry mean for the future of the human species? At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for “illegal medical practice.” As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society? Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity. The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Though the current political climate might lead one to suspect that religion and medicine make for uncomfortable bedfellows, the two institutions have a long history of alliance. From religious healers and religious hospitals to religiously informed bioethics and research studies on the impact of religious and spiritual beliefs on physical and mental well-being, religion and medicine have encountered one another from antiquity through the present day. In Religion and Medicine: A History of the Encounter Between Humanity’s Two Greatest Institutions (Oxford University Press, 2020), Dr. Jeff Levin outlines this longstanding history and the multifaceted interconnections between these two institutions. The first book to cover the full breadth of this subject, it documents religion-medicine alliances across religious traditions, throughout the world, and over the course of history. Levin summarizes a wide range of material in the most comprehensive introduction to this emerging field of scholarship to date. Jeff Levin holds a distinguished chair at Baylor University, where he is university professor of epidemiology and population health, professor of medical humanities, and director of the program on religion and population health at the Institute for the Studies of Religion. Lindsey Jackson is a PhD student at Concordia University in Montreal, Canada. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Séances, clairvoyance, and telepathy captivated public imagination in the United States from the 1850s well into the twentieth century. Though skeptics dismissed these experiences as delusions, a new kind of investigator emerged to seek the science behind such phenomena. With new technologies like the telegraph collapsing the boundaries of time and space, an explanation seemed within reach. As Americans took up psychical experiments in their homes, the boundaries of the mind began to waver. Common Phantoms: An American History of Psychic Science (Stanford UP, 2020) brings these experiments back to life while modeling a new approach to the history of psychology and the mind sciences. Drawing on previously untapped archives of participant-reported data, Alicia Puglionesi recounts how an eclectic group of investigators tried to capture the most elusive dimensions of human consciousness. A vast though flawed experiment in democratic science, psychical research gave participants valuable tools with which to study their experiences on their own terms. Academic psychology would ultimately disown this effort as both a scientific failure and a remnant of magical thinking, but its challenge to the limits of science, the mind, and the soul still reverberates today. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

COVID-19 has had such far-reaching impacts that it can be, and has been, studied from the perspective of almost any academic discipline. For geographers, the ways in which COVID-19 affects place, space and movement is particularly consequential. It is at once a global phenomenon, yet it also ties us to localities in a way not experienced for a very long time in our increasingly mobile and interconnected world. In Southeast Asia, the impact of COVID-19 has been particularly severe for migrant workers, who have found themselves un- or under-employed and sometimes stranded as economic activity has shut down and borders have closed. Professor Hirsch is part of a wide-ranging review of the implications of COVID-19 for migrant workers across the Asia-Pacific region, bringing in four main dimensions: what does it mean in terms of governance/rights, gender, public health and the environment? On the occasion of International Migrants Day on 18 December, Professor Philip Hirsch spoke to Dr Natali Pearson about the impact that the pandemic has had on migrant workers in mainland Southeast Asia, and how we can better protect this vulnerable community. Philip Hirsch is Emeritus Professor of Human Geography at the University of Sydney, where he taught from 1987 to 2017. He has written extensively on environment, development, natural resource governance and agrarian change in the Mekong Region. He is now based in Chiang Mai, Thailand. Books published over the past 10 years include the (edited) “Handbook of the Environment in Southeast Asia” (Routledge 2017), (co-authored) “The Mekong: A socio-legal approach to river basin development” (Earthscan 2016), (co-authored) "Powers of Exclusion: Land dilemmas in Southeast Asia" (NUS Press and Hawaii University Press 2011) and (co-edited) "Tracks and Traces: Thailand and the work of Andrew Turton" (Amsterdam University Press 2010). In 2021, University of Washington Press will publish his co-edited, “Turning land into capital: development and dispossession in the Mekong Region”. Professor Hirsch is fluent in Thai and Lao, speaks intermediate Vietnamese and elementary Khmer. For more information or to browse additional resources, visit the Sydney Southeast Asia Centre’s website here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Twentieth-century neuroscience fixed the brain as the basis of consciousness, the self, identity, individuality, even life itself, obscuring the fundamental relationships between bodies and the worlds that they inhabit. In Unraveling: Remaking Personhood in a Neurodiverse Age (University of Minnesota Press, 2020), Matthew J. Wolf-Meyer draws on narratives of family and individual experiences with neurological disorders, paired with texts by neuroscientists and psychiatrists, to decenter the brain and expose the ableist biases in the dominant thinking about personhood. Unraveling articulates a novel cybernetic theory of subjectivity in which the nervous system is connected to the world it inhabits rather than being walled off inside the body, moving beyond neuroscientific, symbolic, and materialist approaches to the self to focus instead on such concepts as animation, modularity, and facilitation. It does so through close readings of memoirs by individuals who lost their hearing or developed trauma-induced aphasia, as well as family members of people diagnosed as autistic--texts that rethink modes of subjectivity through experiences with communication, caregiving, and the demands of everyday life. Arguing for a radical antinormative bioethics, Unraveling shifts the discourse on neurological disorders from such value-laden concepts as "quality of life" to develop an inclusive model of personhood that honors disability experiences and reconceptualizes the category of the human in all of its social, technological, and environmental contexts. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Alan Berkman (1945–2009) was no campus radical in the mid-1960s; he was a promising Ivy League student, football player, Eagle Scout, and fraternity president. But when he was a medical student and doctor, his politics began to change, and soon he was providing covert care to members of revolutionary groups like the Weather Underground and becoming increasingly radicalized by his experiences at the Wounded Knee takeover, at the Attica Prison uprising, and at health clinics for the poor. When the government went after him, he went underground and participated in bombings of government buildings. He was eventually captured and served eight years in some of America's worst penitentiaries, barely surviving two rounds of cancer. After his release in 1992, he returned to medical practice and became an HIV/AIDS physician, teacher, and global health activist. In the final years of his life, he successfully worked to change U.S. policy, making AIDS treatment more widely available in the global south and saving millions of lives around the world. In Co-Conspirator for Justice: The Revolutionary Life of Dr. Alan Berkman (UNC Press, 2020), Susan M. Reverby sheds fascinating light on questions of political violence and revolutionary zeal in her account of Berkman's extraordinary transformation from doctor to co-conspirator for justice. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Her third book, an examination of the history of acupuncture as a means of social and political revolution, is forthcoming from the University of Michigan Press. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

At first glance, the term “expressive individualism” seems benign enough. After all, people throughout the Western world value their personal freedom and the liberty to make crucial life decisions such as whether to have children and how and when they wish to die. What could possibly be wrong with the idea that everyone should be in control of his or her own body and fate to the greatest extent possible and with the least intrusion by either the state or “outdated” social mores? But there is a dark side to expressive individualism when one enters the realm of public bioethics. In his 2020 book What It Means to Be Human: The Case for the Body in Public Bioethics (Harvard University Press, 2020), O. Carter Snead defines for us what the term “public bioethics” encompasses and provides a much-needed genealogy of the field. He profiles key players in many of the most momentous bioethics-related developments of the post-WWII era from physicians such as Henry Knowles Beecher to jurists like Harry Blackmun and influential scholars in fields such as philosophy and sociology like Alasdair MacIntyre, Charles Taylor and Robert Bellah. Snead chronicles how the field of bioethics came to be shaped by shocking revelations of cases of inhumanity many of which are well-known (such as the infamous Tuskegee Syphilis Study) but many of which are rarely discussed such as medical experiments performed on near-term alive aborted babies. Such cases shocked the public and led to legislation creating commissions and other bodies designed to prevent such horrors. But Snead argues that much of the action on the public policy front failed for multiple reasons and left vulnerable groups (e.g., the aged, the cognitively disabled, the unborn) outside a legal regime built upon the precepts of expressive individualism. And even those who were supposedly able to express their wishes were often harmed by the expressive individualism paradigm and its legal framework. Snead gives examples of the many actors in the area of assisted reproduction and assisted suicide whose rights can be trampled in the name of a notion of personal liberty that does not account for changes of mind. He also demonstrates that regulation and oversight was often, for all intents and purposes, absent in many cases. Snead’s book is a clarion call for what he calls “remembering the body.” This is an important book for anyone who may at some point become ill or disabled or who will end up caring for someone who is. That is, it is a book for everyone. It is by a leading scholar, but its readership is anyone with a body and who loves other people—or at least has some control over them. Give a listen. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

While many doctors claim that Lyme disease--a tick-borne bacterial infection--is easily diagnosed and treated, other doctors and the patients they care for argue that it can persist beyond standard antibiotic treatment in the form of chronic Lyme disease. In Divided Bodies: Lyme Disease, Contested Illness, and Evidence-Based Medicine (Duke UP, 2020), Abigail A. Dumes offers an ethnographic exploration of the Lyme disease controversy that sheds light on the relationship between contested illness and evidence-based medicine in the United States. Drawing on fieldwork among Lyme patients, doctors, and scientists, Dumes formulates the notion of divided bodies: she argues that contested illnesses are disorders characterized by the division of bodies of thought in which the patient's experience is often in conflict with how it is perceived. Dumes also shows how evidence-based medicine has paradoxically amplified differences in practice and opinion by providing a platform of legitimacy on which interested parties--patients, doctors, scientists, politicians--can make claims to medical truth. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

An estimated 80 million people live with a neurodegenerative disease, with this number expected to double by 2050. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. The time to rethink degenerative brain disorders has come. With no biological boundaries between neurodegenerative diseases, illnesses such as Parkinson's and Alzheimer's result from a large spectrum of biological abnormalities, hampering effective treatment. In Brain Fables: The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them (Cambridge UP, 2020), acclaimed neurologist Dr Alberto Espay and Parkinson's advocate Benjamin Stecher present compelling evidence that these diseases should be targeted according to genetic and molecular signatures rather than clinical diagnoses. There is no Parkinson's or Alzheimer's, simply people with Parkinson's or Alzheimer's. An incredibly important story never before told, Brain Fables is a wakeup call to the scientific community and society, explaining why we have no effective disease-modifying treatments, and how we can get back on track. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. You can reach her at [email protected]. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Reducing harm or shrinking the likelihood of accidental death are remarkably contentions projects—in areas from sex education, to pandemic management, to drug use. Nancy Campbell’s important new book, OD: Naloxone and the Politics of Overdose (MIT Press, 2020) explores how a therapy that can stop an accidental drug overdose, called Naloxone, emerged in the American mainstream in the early years of the new millennium—despite existing in some form for nearly a century. What are now called “opioid antagonists” were used, not to save lives, but deployed by the carceral state to police drug users in the early twentieth century; sequestered within bioscience laboratories to build molecular theories of how the brain worked at midcentury; approved by the FDA in 1971 for the treatment of overdose only by physicians; and illicitly administered and widely shared in the 1980s and 1990s among drug-user-led activist organizations and communities, who created their own troves of training protocols, peer-education networks, and experiential evidence of its effectiveness. In the twenty-first century, Naloxone appeared on public policy agendas around harm reduction and arrived legally in the hands of the people best situated to intervene when an overdose was underway—but only in some US states and some countries. Campbell tunes readers’ ears to the politics of evidence, the health effects of stigma, and the racism of false medical claims as she listens, amid a century of contention, to the quietness of “undone science.” As evidence, this intrepid book uses visual culture, vernacular documents, oral histories, and (expertly explained) scientific publications. It connects American histories at federal and local levels with the UK and especially Scotland. And it relates medical communities and activist networks without imposing false divides or drawing caricatures of either. The book builds on Campbell’s four previous books on the history of addiction, gendering knowledge, and social theory from the position of Science and Technology Studies. The interview was a collaborative project among participants in the Vanderbilt University course, American Medicine & the World. For information about using NBN interviews as part of pedagogical practice, please email Laura Stark or see the essay “Can New Media Save the Book?” in Contexts (2015). Laura Stark is Associate Professor at Vanderbilt University’s Center for Medicine, Health, and Society, and Associate Editor of the journal History & Theory. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

Globally, breast cancer is the most commonly diagnosed cancer in women, with over 1 million cases detected annually. The disease is particularly worrisome in Vietnam, where breast cancer incidence has more than doubled over the last two decades, making it the leading cancer among Vietnamese women, ahead of cervical and uterine cancers. It has also demonstrated a high level of aggressiveness, with over 80% of breast cancer patients presenting with local or distant metastases, while only 28% of breast cancers in Australia were diagnosed in late stages. Thus mortality rates are twofold higher in Vietnam compared with developed countries. Professor Patrick Brennan talks to Dr Natali Pearson about his decade-long work on improving breast cancer detection in Vietnam. Professor Patrick Brennan is a leading researcher at the University of Sydney's School of Health Sciences. His research involves exploring novel technologies and techniques that enhance the detection of clinical indicators of disease, whilst minimising risk to the patient. His research has involved most major imaging modalities including X-ray, computerised tomography, ultrasound and magnetic resonance imaging, with a particular focus on breast and chest imaging. His research findings have translated into improved diagnosis and management of important disease states such as cancer, musculo-skeletal injury, arthritis and multiple sclerosis. For more information or to browse additional resources, visit the Sydney Southeast Asia Centre’s website here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

We often hear stories of people in terrible and seemingly intractable situations who are preyed upon by someone offering promises of help. Frequently these cases are condemned in terms of "exploiting hope." These accusations are made in a range of contexts: human smuggling, employment relationships, unproven medical 'cures.' We hear this concept so often and in so many contexts that, with all its heavy lifting in public discourse, its actual meaning tends to lose focus. Despite its common use, it can be hard to understand precisely what is wrong about exploiting hope what can accurately be captured under this concept, and what should be done. In Exploiting Hope: How the Promise of New Medical Interventions Sustains Us--and Makes Us Vulnerable (Oxford UP, 2020), philosopher Jeremy Snyder offers an in-depth study of hope's exploitation. First, he examines the concept in the abstract, including a close look at how this term is used in the popular press and analysis of the concepts of exploitation and hope. This theory-based section culminates in a definitive account of what it is to exploit hope, and when and why doing so is morally problematic. The second section of the book examines the particularly dangerous cases in which unproven medical interventions target the most vulnerable: for example, participants in clinical trials, purchasing unproven stem cell interventions, "right to try" legislation, and crowdfunding for unproven medical interventions. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

The figure of Sigmund Freud has captivated the Western imagination like few others. One hundred and twenty-five years after the publication of Studies on Hysteria, the good doctor from Vienna continues to stir controversy in institutions, academic circles, and nuclear households across the world. Perhaps Freud’s sharpest and most adamant critic, Frederick Crews has been debating Freud’s legacy for over thirty years. His latest work, Freud: The Making of an Illusion (Picador, 2018) challenges us with an extensive psychological profile of the legend here revealed as scam artist. What some analysts might argue to be a 750 page character assassination, Crews maintains is simply a recitation of facts which leaves readers to draw their own conclusions. One might wonder if the story of facts that is conveyed is not itself a counter myth. Was Freud a megalomaniacal, greedy, cocaine-addled opportunist and psychoanalysis a pseudoscience that has reigned tyrannically over twentieth century thought? Making use of Freud’s extensive letters to Martha Bernays, Crews paints a “damning portrait” (Esquire) of a money hungry, adulterous, and uncaring man. How can this portrait be reconciled with the radically meaningful and deeply transformative process many of us know psychoanalysis to be? Is the tyranny of rationality preferable to the tyranny of myth? Does the unmaking of the myth of the man undo the gift of his work? In this interview Crews responds to questions of what it means to have an empirical attitude, how we should “test” the process of healing, what’s so tempting about Freud, and what should become of psychoanalysis today. Meticulously researched, the Crews of the Freud wars is back again, and he’s going in for the kill shot. Cassandra B. Seltman is a writer, psychoanalyst, and researcher in NYC. [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine