Neurology® Podcast

1) Progressive multifocal leukoencephalopathy and 2) Topic of the month: Featured speakers from the AAN Meeting. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Scagnelli interviews Dr. Sandra Richman about her paper on progressive multifocal leukoencephalopathy. In the next segment, Dr. Sarah Song is reading our e-Pearl of the week about sickle cell disease and stroke. In the next part of the podcast Dr. Alberto Espay interviews Dr. Stephen Hauser about the Robert Wartenberg Lecture. The LOTWs for the next two weeks of May will be interviews with Drs. Griggs and Daube. The participants had nothing to disclose except Drs. Richman, Song, Espay and Hauser.Dr. Richman is a full-time employee of Biogen Idec.Dr. Song served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Espay serves on scientific advisory boards for Boehringer Ingelheim and Solvay Pharmaceuticals, Inc.; serves on the editorial advisory board for The European Neurological Journal; has received speaker honoraria from UCB/SCHWARZ PHARMA, Medtronic, Inc., and Novartis; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; has served on speakers' bureaus for UCB/SCHWARZ PHARMA and Novartis; receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the KL2 Research Scholars mentored career development award, and NIH Institutional Clinical and Translational Science Award (RR026315-02), Dean Scholar's Award - University of Cincinnati, Davis Phinney Foundation, and the Michael J Fox Foundation. Dr. Hauser has served as both a scientific advisory board member and consultant to BioMarin Pharmaceutical Inc. and Receptos Inc., and as a consultant to Novartis; has received travel accommodations from Roche; his institution (UCSF) has received speaker honoraria from Wyeth-Pfizer Inc; serves as Editor-in-Chief of Annals of Neurology; receives publishing royalties for Harrison's Principles of Internal Medicine (McGraw-Hill Publishers, 1994-present); and has received stock options from Receptos Inc., all of which were transferred to his institution (UCSF).

1) Voltage sensor mutations and 2) Topic of the month: Featured speakers from the AAN Meeting. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Steve Cannon about his paper on voltage sensor mutations. In the next segment, Dr. Sarah Song is reading our e-Pearl of the week about Cogan's sign. In the next part of the podcast Dr. Alberto Espay interviews Dr. Robert Griggs about his Presidential Lecture. The LOTWs for the next three weeks of May will continue with more featured speakers from the AAN Meeting being interviewed. The participants had nothing to disclose except Drs. Burns, Cannon, Song, Espay and Griggs.Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Cannon serves on the scientific advisory board for Telethon (Italy); serves on the editorial advisory board of the Journal of General Physiology; and receives research support from the NIH/NIAMS. Dr. Song served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Espay serves on scientific advisory boards for Boehringer Ingelheim and Solvay Pharmaceuticals, Inc.; serves on the editorial advisory board for The European Neurological Journal; has received speaker honoraria from UCB/SCHWARZ PHARMA, Medtronic, Inc., and Novartis; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; has served on speakers' bureaus for UCB/SCHWARZ PHARMA and Novartis; receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the KL2 Research Scholars mentored career development award, and NIH Institutional Clinical and Translational Science Award (RR026315-02), Dean Scholar's Award - University of Cincinnati, Davis Phinney Foundation, and the Michael J Fox Foundation. Dr. Griggs serves as Chair of Executive Committee of the Muscle Study Group, which receives support from pharmaceutical companies; has served on scientific advisory boards for The National Hospital Queen Square and PTC Therapeutics, Inc.; serves on the editorial boards of NeuroTherapeutics and Current Treatment Opinions in Neurology; receives royalties from the publication of Andreoli and Carpenter's Cecil Essentials of Medicine, Eighth Edition (W.B. Saunders Company, 2000, 2004, 2007 and 2010) and Cecil Textbook of Medicine, 24th Edition (Saunders, 2000, 2004, 2008 and 2010 in press); has received research support from TaroPharma and the NIH (NINDS T32 NS07338 [PI and preceptor], 2 U54 NS059065-06 [PI], R01 NS045686-05 [PI], and NINDS 525326 [Co-PI]), the FDA, and from the Muscular Dystrophy Association.

1) Idiopathic intracranial hypertension and 2) Topic of the month: Featured speakers from the AAN Meeting. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Beau Bruce interviews Dr. Melissa Ko about her paper on idiopathic intracranial hypertension. In the next segment, Dr. Sarah Song is reading our e-Pearl of the week about carotid-cavernous fistula. In the next part of the podcast Dr. Alberto Espay interviews Dr. Serge Przedborski about his talk on Neurodegeneration: Models and mechanisms. Over the subsequent four weeks, Dr. Espay will interview other featured speakers from the AAN Meeting. The participants had nothing to disclose except Drs. Bruce, Song and Espay.Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.Dr. Song served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Espay serves on scientific advisory boards for Boehringer Ingelheim and Solvay Pharmaceuticals, Inc.; serves on the editorial advisory board for The European Neurological Journal; has received speaker honoraria from UCB/SCHWARZ PHARMA, Medtronic, Inc., and Novartis; has received honoraria from Novartis, the American Academy of Neurology, and the Movement Disorders Society; has served on speakers' bureaus for UCB/SCHWARZ PHARMA and Novartis; receives/has received research support from Medtronic, Inc., Allergan, Inc., CleveMed, the KL2 Research Scholars mentored career development award, and NIH Institutional Clinical and Translational Science Award (RR026315-02), Dean Scholar's Award - University of Cincinnati, Davis Phinney Foundation, and the Michael J Fox Foundation.

1) Sydenham chorea and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Waugh interviews Dr. Fabienne Brilot-Turville about her paper on antibody binding to neuronal surface in Sydenham chorea. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about fragile X-associated tremor ataxia syndrome. In the next part of the podcast Dr. Farrah Mateen completes our historical interviews for the month by interviewing Dr. Jerome Posner. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Brilot-Turville, Clardy and Mateen.Dr. Brilot-Turville has received research support from the Tourette Syndrome Association, USA, the Brain Foundation Australia, and the Trish Multiple Sclerosis Foundation Australia. Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mateen served on the editorial team for the Neurology® Resident and Fellow Section and is supported by the 2010 Practice Research Grant from the American Academy of Neurology.

1) AD dementia and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Brad Dickerson about his paper on AD dementia in cognitively normal adults. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about ocular bobbing. In the next part of the podcast Dr. Farrah Mateen interviews Dr. Peter Dyck for our next historical interview. The participants had nothing to disclose except Drs. Dickerson, Clardy, Mateen and Dyck.Dr. Dickerson serves on the editorial board of Hippocampus; and receives research support from the NIH and the Alzheimer's Association.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mateen served on the editorial team for the Neurology® Resident and Fellow Section and is supported by the 2010 Practice Research Grant from the American Academy of Neurology.Dr. Dyck receives research support from the NIH and the FDA

1) Folic acid supplementation and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Nathan Fountain interviews Drs. Sheffali Gulati and Ravindra Arya about their paper on folic acid supplementation. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about the 'hot and dry foot' as a sign of cancer. In the next part of the podcast Dr. Farrah Mateen interviews Dr. C. Miller Fisher as we continue our month of historical interviews. The participants had nothing to disclose except Drs. Fountain, Gulati, Clardy and Mateen.Dr. Fountain serves on the Scientific Advisory Board and has received funding for travel from UCB; serves on the editorial board of Epilepsy Currents; estimates that 10% of his clinical effort at the University of Virginia EEG Lab is spent on EEG interpretation; receives research support from UCB, Vertex Pharmaceuticals, Sepracor Inc., Medtronic, Inc., NeuroPace, Inc., and the NIH (R01 NS 058634- 01A2m [Site PI] and U01 NS 053998 [Site PI],Dr. Gulati serves on the editorial board of the Indian Journal of Pediatrics; and receives research support from the NIH, Autism Speaks, and National Trust.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mateen served on the editorial team for the Neurology® Resident and Fellow Section and is supported by the 2010 Practice Research Grant from the American Academy of Neurology.

1) Neuromyelitis optica and 2) Topic of the month: Historical interviews. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Pearce Korb interviews Drs. Claudia Lucchinetti and Bogdan Popescu about their paper on neuromyelitis optica unique area postrema lesions. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about striatal hand and foot. In the next part of the podcast Dr. Farrah Mateen interviews Dr. Bud Rowland as part of our month of historical interviews. Over the subsequent three weeks, Dr. Mateen will interview Drs. C. Miller Fisher, Peter Dyck and Jerome Posner. The participants had nothing to disclose except Drs. Lucchinetti, Clardy, Mateen and Rowland.Dr. Lucchinetti may accrue revenue for a patent re: aquaporin-4 associated antibodies for diagnosis of neuromyelitis optica; receives royalties from the publication of Blue Books of Neurology: Multiple Sclerosis 3 (Saunders Elsevier, 2010); and receives research support from the NIH, the Guthy Jackson Charitable Foundation (PI), and the National MS Society.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mateen served on the editorial team for the Neurology® Resident and Fellow Section and is supported by the 2010 Practice Research Grant from the American Academy of Neurology.Dr. Rowland serves as Ombudsman for Neurology; receives royalties from the publication of Merritt's Neurology (Lippincott Williams & Wilkins, 2005); and served as Editor-in-Chief of Neurology Today.

1) Improvement of migraines and 2) Topic of the month: Sports neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Heather Harle interviews Dr. Dale Bond about his paper on improvement of migraines after bariatric surgery. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about hyperventilation: test for diagnosing absence seizures. In the next part of the podcast Dr. Howard Goodkin interviews Dr. Jeff Kutcher about peripheral nerve injury to finish the month about sports neurology. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Bond, Fugate and Goodkin.Dr. Bond serves on the editorial boards of Surgery for Obesity and Related Diseases and American Journal of Health Behavior; and receives research support from the NIH (NIDDK/ NCI). Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Goodkin serves on the scientific board for Tuberous Sclerosis Alliance and CURE; serves on the editorial board for Neurology and Surgical Neurology International; receives royalties from the publication of the book The choking game and other strangulation activities in children and adolescents; and is funded by NIH grants [R01 NS067439 PI and R01 NS48413 PI].

1) Traumatic brain injury and 2) Topic of the month: Sports neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Drs. Erik Ensrud and Brian Edlow interviews Dr. Jordan Grafman about his paper on traumatic brain injury. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about TCD in brain death. In the next part of the podcast Dr. Howard Goodkin interviews Dr. Jeff Kutcher about post-concussion syndrome. The LOTW for the last week of March will be about peripheral nerve injury. The participants had nothing to disclose except Drs. Grafman, Fugate and Goodkin.Dr. Grafman serves as Co-editor of Cortex and receives research support from the Intramural Research Program NIH/NINDS and the Henry M. Jackson Foundation.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Goodkin serves on the scientific board for Tuberous Sclerosis Alliance and CURE; serves on the editorial board for Neurology and Surgical Neurology International; receives royalties from the publication of the book The choking game and other strangulation activities in children and adolescents; and is funded by NIH grants [R01 NS067439 PI and R01 NS48413 PI].

1) Guillain-Barré syndrome and 2) Topic of the month: Sports neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Bart Jacobs about his paper on Guillain-Barré syndrome. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about early handedness a sign of presumed perinatal stroke. In the next part of the podcast Dr. Howard Goodkin interviews Dr. Jeff Kutcher about concussion diagnosis. The LOTWs for the next two weeks of March will be post-concussion syndrome and peripheral nerve injury. The participants had nothing to disclose except Drs. Burns, Jacobs, Fugate and Goodkin.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Jacobs has received funding for travel from Baxter International Inc.; and has received research support from the Netherlands Organization for Health Research and Development, the Prinses Beatrix Fonds, and from GBS-CIDP Foundation International. Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Goodkin serves on the scientific board for Tuberous Sclerosis Alliance and CURE; serves on the editorial board for Neurology and Surgical Neurology International; receives royalties from the publication of the book The choking game and other strangulation activities in children and adolescents; and is funded by NIH grants [R01 NS067439 PI and R01 NS48413 PI].

1) Income gap in medical practice and 2) Topic of the month: Sports neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alex Bragg interviews Dr. Bruce Sigsbee about his paper on income gap in medical practice. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about Sneddon syndrome. In the next part of the podcast Dr. Howard Goodkin interviews Dr. Jeff Kutcher about chronic traumatic encephalopathy and retirement. The LOTWs for the next three weeks of March will be concussion diagnosis, post-concussion syndrome and peripheral nerve injury. The participants had nothing to disclose except Drs. Sigsbee, Fugate and Goodkin.Dr. Sigsbee as President-Elect of the American Academy of Neurology receives a stipend.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Goodkin serves on the scientific board for Tuberous Sclerosis Alliance and CURE; serves on the editorial board for Neurology and Surgical Neurology International; receives royalties from the publication of the book The choking game and other strangulation activities in children and adolescents; and is funded by NIH grants [R01 NS067439 PI and R01 NS48413 PI].

1) Brain death and the courts and 2) Topic of the month: Sports neurology. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Dan Larriviere interviews Ms Agnes Schipper about her paper on brain death and the courts. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about junctional scotoma. In the next part of the podcast Dr. Howard Goodkin interviews Dr. Jeff Kutcher about second impact syndrome and RTP. Over the subsequent four weeks, Dr. Goodkin will interview Dr. Kutcher about concussions. The participants had nothing to disclose except Drs. Larriviere, Fugate and Goodkin.Dr. Larriviere serves as a consultant for Allergan, Inc.; and serves on the editorial board of Neurology Today.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Goodkin serves on the scientific board for Tuberous Sclerosis Alliance and CURE; serves on the editorial board for Neurology and Surgical Neurology International; receives royalties from the publication of the book The choking game and other strangulation activities in children and adolescents; and is funded by NIH grants [R01 NS067439 PI and R01 NS48413 PI].

1) Paraneoplastic disease and 2) Topic of the month: Neurotoxins. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jennie Taylor interviews Dr. Bruce Giometto about his paper on paraneoplastic disease. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about diencephalic syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. John Pearn about ciguatera poisoning for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Clardy and Bruce.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.

1) Motor cortex inhibition and 2) Topic of the month: Neurotoxins. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Mytinger interviews Dr. Don Gilbert about his paper on motor cortex inhibition. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about ictal asystole. In the next part of the podcast Dr. Beau Bruce interviews Dr. Jonathan Rutchik about neurolgic effects of organic solvents for our Lesson of the Week. Next week, we will discuss ciguatera poisoning. The participants had nothing to disclose except Drs. Gilbert, Clardy and Bruce.Dr. Gilbert has received honoraria from the Tourette Syndrome Association/ Centers for Disease Control, the Movement Disorder Society, the American Academy of Neurology, and the American Academy of Pediatrics; serves on the medical advisory board for the Tourette Syndrome Association; writes board review questions for PREP SA (American Academy of Pediatrics); has received research support from the NIH [NIMH R01 MH078160, NIMH R01 MH08185, and NINDS NS056276], and from Cincinnati Children's Hospital Research Foundation, the University of Cincinnati, and the Tourette Syndrome Association.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.

1) Cerebrovascular re-events and 2) Topic of the month: Neurotoxins. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Michael Knoflach interviews Dr. Mira Katan about her paper on stress hormones predicting cerebrovascular re-events. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about "candle guttering" sign in tuberous sclerosis. In the next part of the podcast Dr. Beau Bruce interviews Dr. David Bellinger about neurologic effects of lead toxicity for our Lesson of the Week. The Lesson of the Weeks for the last two weeks of February will be organic solvents and ciguatera poisoning. The participants had nothing to disclose except Drs. Katan, Burns, Clardy and Bruce.Dr. Katan has received speaker honoraria from B - R - A - H - M - S GmbH.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section.

1) Zoster sine herpete and 2) Topic of the month: Neurotoxins. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Don Gilden about his paper on zoster sine herpete. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about Sturge-Weber syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. Christian Sandrock about botulism and botulinum toxin for our Lesson of the Week. Over the next subsequent three weeks, we will interview other specialists about neurotoxins. The participants had nothing to disclose except Drs. Burns, Gilden, Clardy and Bruce.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Gilden serves as Senior Associate Editor for the Journal of Neurovirology and on the editorial boards of In Vivo, the Journal of Virology, Scientific American Medicine, Virus Genes, and Neurology; and receives research support from the NIH.Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section.

1) Child development following in utero exposure and 2) Topic of the month: Interviews with Dr. Oliver Sacks. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Mytinger interviews Dr. Gus Baker about his paper on child development following in utero exposure. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about burning mouth syndrome. In the next part of the podcast Dr. Ted Burns interviews Dr. Oliver Sacks about his thoughts about being a patient and a neurologist. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Baker, Fugate and Burns.Dr. Baker has served on a scientific advisory board for sanofi-aventis; serves on the editorial board of Epilepsy and Behaviour; has received speaker honoraria from Eisai Inc.; has received educational support from UCB, sanofi-aventis, and Pfizer Inc; and receives research support from Epilepsy Research UK, Medical Research Council UK, and Epilepsy Action UK.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section.

Plasmapheresis in neurolgic disorders: guideline update and 2) Topic of the month: Interviews with Dr. Oliver Sacks. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Michelle Mauermann interviews Dr. Irene Cortese about the evidence-based update on plasmapheresis in neurologic disorders. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about triple-a-sign in Lambert Eaton syndrome. In the next part of the podcast Dr. Ted Burns interviews Dr. Oliver Sacks about posterior cortical atrophy and visual agnosias for our Lesson of the Week. Over the next subsequent two weeks, we will continue to discuss other interesting topics with Dr. Oliver Sacks. The participants had nothing to disclose except Drs. Fugate and Burns.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section.

Repeat brain death examinations and 2) Topic of the month: Interviews with Dr. Oliver Sacks. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Dana Lustbader about her paper on repeat brain death examinations. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about unilateral photophobia or phonophobia. In the next part of the podcast Dr. Ted Burns interviews Dr. Oliver Sacks about prosopagnosia and the fusiform gyrus for our Lesson of the Week. Over the next subsequent two weeks, we will continue to discuss other interesting topics with Dr. Oliver Sacks. The participants had nothing to disclose except Drs. Kissela, Lustbader Fugate and Burns.Dr. Kissela served on the scientific advisory board for Allergan, Inc in 2009; served as a consultant for Allergan for 2-day meeting in 2009; received honoraria from CME program and unrestricted educational grants; received research support from the NIH [R01 NS 30678], [N01 NS 081588], [1Ul1 RR026314] and received compensation for reviewing records for several medical/legal cases regarding stroke.Dr. Lustbader is a consultant for the American Board of Internal Medicine and serves on the Test Writing Committee for Palliative Medicine.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section.

First paper ever published in Neurology in 1951 and 2) Topic of the month: Interviews with Dr. Oliver Sacks. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Drs. Lewis Rowland, Robert Daroff, and Robert Griggs about the first paper ever published in Neurology on past, present and future of neurology. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about bobble head doll syndrome. In the next part of the podcast Dr. Ted Burns interviews Dr. Oliver Sacks about alexia without agraphia and the left inferotemporal gyrus for our Lesson of the Week. Over the next subsequent three weeks, we will highlight other neurologic disorders Dr. Oliver Sacks writes about in his new book, The Mind's Eye. The participants had nothing to disclose except Drs. Burns, Rowland Griggs and Fugate.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Rowland serves as Ombudsman for Neurology; receives royalties from the publication of Merritt's Neurology (Lippincott Williams & Wilkins, 2005); and served as Editor-in-Chief of Neurology Today. Dr. Griggs serves on the editorial advisory board for Current Treatment Options in Neurology and NeuroRX; has received honoraria for lectures or educational activities not funded by industry; receives research support from the NINDS T32 NS07338 [PI]; NIH 2U54 NS059065-06 [PI], R01 NS045686-05 [PI], NIH-R13 Fostering Pharma, NINDS 525326 FOR-DMD, and FDA 2-RO1FD003454-02 [Co-PI] and TaroPharma; receives funding support from MDA Fostering Pharma-Academic Partnerships in Neuromuscular Experimental Therapeutics, Muscular Dystrophy Association Experimental Therapeutics of Neuromuscular Disease and Recruitment for HYP HOP Phase III trial in the Periodic paralyses (PI); and receives royalties from the publication of the book, Cecil Textbook of Medicine, 23 Edition. Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section.

Bihemispheric brain stimulation and 2) Topic of the month: Treatment of tremor in PD. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Drs. Gottfried Schrang and Robert Lindenberg about their paper on bihemispheric brain stimulation. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about the clinical syndrome of spinal cord lesions. In the next part of the podcast Dr. Shanna Patterson interviews Dr. Blair Ford for the next part of our discussion on surgical treatment of tremor in PD for our Lesson of the Week. The participants had nothing to disclose except Drs. Kissela, Schlaug, Overman, and Ford. Dr. Kissela served on the scientific advisory board for Allergan, Inc in 2009; served as a consultant for Allergan for 2-day meeting in 2009; received honoraria from CME program and unrestricted educational grants; received research support from the NIH [R01 NS 30678], [N01 NS 081588], [1Ul1 RR026314] and received compensation for reviewing records for several medical/legal cases regarding stroke.Dr. Schlaug receives research support from the NIH (NINDS 1R01NS045049 [PI], NIDCD 1RO1 DC008796 [PI], and NIDCD R01 DC009823-01 [PI]), and from the National Science Foundation. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Ford serves on the scientific advisory board for Medtronic, Inc., and receives in his clinical practice as Medical Director for Movement Disorder Surgery at Columbia University (25% effort).

1) Transient RLS and 2) Topic of the month: Treatment of tremor in PD. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Dr. Mauro Manconi and Prof. Luigi Ferin-Strambi about their paper on transient RLS. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about medullary signs in neuromyelitis optica. In the next part of the podcast Dr. Shanna Patterson interviews Dr. Blair Ford about medical treatment of tremor in PD for our Lesson of the Week. Next week, we will highlight the second part of this interview which will discuss surgical treatment of tremor. The participants had nothing to disclose except Drs. Espay, Overman, Ford and Prof. Luigi Ferin-Strambi. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Prof. Ferini-Strambi serves as Field Editor for Sleep Medicine. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Ford serves on the scientific advisory board for Medtronic, Inc., and receives in his clinical practice as Medical Director for Movement Disorder Surgery at Columbia University (25% effort).

1) AAN quality measures on Parkinson disease and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Eric Cheng about the AAN quality measures on Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barre mimics: Amiodarone neurotoxicity. In the next part of the podcast Dr. Beau Bruce interviews Dr. James Howard for the last part of our discussion on neuro-muscular disease with this week being about acetylcholine esterase inhibitors for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Burns, Cheng and, Overman. Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Cheng serves as a consultant for the National Parkinson Foundation; and receives research support from the NIH/NINDS (K23NS058571 [PI]), the VA Parkinson's Disease Research, Education, and Clinical Center, the Department of Veterans Affairs, the California Office of Statewide Planning and Development, the National Multiple Sclerosis Society, and the American Heart Association. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

1) Corticobasal syndrome and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Drs. Jennifer Whitwell and Keith Josephs about their paper on corticobasal syndrome. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barre mimics: Buckthorn neurotoxicity. In the next part of the podcast Dr. Beau Bruce interviews Dr. Rahman Pourmand for the next part of our discussion on Lambert-Eaton myasthenic syndrome for our Lesson of the Week. The participants had nothing to disclose except Drs. Espay, Whitwell, Josephs, and Overman. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Dr. Whitwell receives research support from the Dana Foundation and the NIH (R01- DC010367 [coinvestigator] and R01-AG037491 [coinvestigator]).Dr. Josephs receives research support from the NIH (NIDCD R01- DC010367 [PI], NIA R01-AG037491 [PI], and NINDS 2P50 NS040256-10 [coinvestigator]) and the Dana Foundation.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

Hallucinations and sleep disorders and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Scott Kohler interviews Drs. Christopher Goetz and Glenn Stebbins about their paper on hallucinations and sleep disorders in PD. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about mimics of Guillain-Barre syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. Gil Wolfe for the next part of our discussion on treatments for myasthenia gravis for our Lesson of the Week. The participants had nothing to disclose except Drs. Goetz, Stebbins, and Overman. Dr. Goetz serves on a scientific advisory board for the Parkinson's Disease Foundation; served as Editor-in-Chief of Movement Disorders; receives royalties from the publication of Textbook of Clinical Neurology, 3rd edition (Saunders, 2007) and Jean-Martin Charcot: Constructing Neurology (Oxford University Press, 1995); has served as a consultant for Asubio Pharmaceuticals, Inc., Boehringer Ingelheim, IMPAX Laboratories, Inc., i3 Research, Ingenix, Neurim Pharmaceuticals, Novartis, Osmotica Pharmaceutical Corp., Oxford BioMedica Plc, Solvay Pharmaceuticals, Inc., Solvay Pharmaceuticals, Inc., Teva Pharmaceutical Industries Ltd., United Biosource Corporation and UCB; receives research support from Boehringer Ingelheim, Ceregene, Merck Serono, Santhera Pharmaceuticals, the NIH (U01NS043127-09 [Consultant], U01NS043127-09 [Consultant], 1K23 NS060949-02 [Mentor], and 5K23 NS052487-05 [Mentor]), and the Michael J Fox Foundation; and directs the Rush Parkinson's Disease Research Center, which receives support from the Parkinson's Disease Foundation. Dr. Stebbins has served/serves on the editorial boards of Movement Disorders and the Journal of Clinical and Experimental Neuropsychology; and receives research support from the NIH (NIA AG09466 [Co-PI] and NINDS N057514 [Coinvestigator]), the American Cancer Society, the Michael J. Fox Foundation for Parkinson Research, and the Fragile-X Foundation.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

1) NMDA receptor antibodies and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Drs. Harald Pruss, Josep Dalmau and Klaus-Peter Wandinger about their paper on NMDA receptor antibodies. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about acute intermittent porphyria as a mimic of Guillain-Barré syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. Ted Burns for the next part of our discussion on diagnostic testing for myasthenia gravis for our Lesson of the Week. Over the subsequent three weeks, we will continue to highlight other areas of the frontal cortex. The participants had nothing to disclose except Drs. Dalmau, Wandinger, Overman, and Burns. Dr. Dalmau has received royalties from a patent re: Ma2 autoantibody test and has patents pending re: NMDA and GABAB receptor autoantibody tests (license fee payments received from EUROIMMUN AG); and receives research support from funding from EUROIMMUN AG and the NIH/NCI [RO1CA107192 (PI) and RO1CA89054-06A2 (PI)].Dr. Wandinger is a full-time employee of and holds stock in EUROIMMUN AG. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Acute ischemic stroke and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Ms. Elizabeth Mostofsky about her paper on acute ischemic stroke onset. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barré in patients with HIV infection. In the next part of the podcast Dr. Beau Bruce interviews Dr. Ted Burns about diagnosis of myasthenia gravis for our Lesson of the Week. Over the next subsequent four weeks, we will highlight neuro-muscular disease. The participants had nothing to disclose except Ms. Mostofsky, Overman, and Burns. Ms. Mostofsky receives research support from the NIH/NIAID (T32-A1007535-11).Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Pneumococcal meningitis and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bart Nathan interviews Drs. Matthijs Brouwer and Diederik van de Beek about their paper on pneumococcal meningitis. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about REM sleep behavior disorder in the synucleinopathies. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the last part of our discussion on bedside testing of the frontal lobes for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Van de Beek, Overman, and Burns. Dr. van de Beek has received research support from The Netherlands Organization for Health Research and Development and the Academic Medical Center.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Non-convulsive status epilepticus and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alex Menze interviews Dr. Nick Johnson about his paper on non-convulsive status epilepticus. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about hallucinations in dementia with Lewy bodies. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the next part of our discussion on areas of the frontal cortex for our Lesson of the Week. The participants had nothing to disclose except Drs Overman and Burns.

1) Mild Alzheimer disease and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Geoffrey Kerchner about his paper on mild Alzheimer disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about MRI findings in idiopathic intracranial hypertension. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the next part of our discussion on the orbitofrontal cortex for our Lesson of the Week. Over the subsequent two weeks, we will continue to highlight other areas of the frontal cortex. The participants had nothing to disclose except Drs. Kerchner, Overman, and Burns.

1) Falls in Parkinson disease and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Tiffini Voss interviews Dr. Kathy Chung about her paper on reducing falls in Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about stroke in neurocysticercosis. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow about dorsolateral prefrontal cortex for our Lesson of the Week. Over the next subsequent three weeks, we will highlight bedside testing of the frontal cortex. The participants had nothing to disclose except Drs. Voss, Chung, Overman, and Burns. Dr. Chung has received research support from a VA Career Development Award.Dr. Voss has received research support from the University of Rochester for Clinical Monitor for Phase III clinical trial.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) MS quality of life and 2) Topic of the month: Aphasia. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Matthew Wong interviews Dr. Paul Grossman about his paper on MS quality of life, depression and fatigue. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about the accessory deep peroneal nerve. In the next part of the podcast Dr. Alberto Espay interviews Dr. Jerzy Szaflarski for the last part of our discussion on aphasia for our Lesson of the Week. The participants had nothing to disclose except Drs. Grossman, Overman, Espay and Szaflarski.

1) Management of headache and 2) Topic of the month: Aphasia. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Kelly Gwathmey interviews Professor Peter Goadsby about his paper on management of headache. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about electrodiagnostic features of axonal neuropathy. In the next part of the podcast Dr. Alberto Espay interviews Dr. Keith Josephs for the next part of our discussion on aphasias for our Lesson of the Week. The participants had nothing to disclose except Professor Goadsby, Drs. Overman, Espay and Josephs. Prof. Goadsby has served as a consultant for or served on a scientific advisory board for Advanced Bionics, Allergan, Inc., Almirall, Amgen, ATI, AstraZeneca, Belgian Research Council, Boehringer Ingelheim, Bristol-Myers Squibb, Boston Scientific, CoLucid Pharmaceuticals, Coherex Medical, Inc., Eli Lilly & Company, Fidelity Foundation, GlaxoSmithKline, Johnson & Johnson, Kalypsys Inc., Medtronic, Inc., MAP Pharmaceuticals, Inc., Migraine Research Foundation, Migraine Trust, Minster Pharmaceuticals plc, Medical Research Council-UK, Merck & Co., Inc., the NIH/ NINDS (Consultant); Netherlands Research Council, Neuralieve, NeurAxon Inc. NeuroTherapeutics Pharma, Organisation for Understanding Cluster Headache-UK and US, and Pfizer Inc; receives royalties from the publication of Mechanism and Management of Headache, 7th ed. (Elsevier, 2005); and has received research support from GlaxoSmithKline, Neuralieve, Merck & Co., Inc., Johnson & Johnson, and MAP Pharmaceuticals, Inc. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Dr. Josephs is funded by R01- DC010367 (PI), the Dana Foundation (PI), and the Morris K. Udall PD Research Center of Excellence NIH/NINDS P50 NS40256 (Co-I).

1) Muscular dystrophy and 2) Topic of the month: Aphasia. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Elliot Dimberg interviews Dr. Richard Finkel about his paper on muscular dystrophy. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about anti-NMDA receptor antibody encephalitis. In the next part of the podcast Dr. Alberto Espay interviews Dr. Keith Josephs for the next part of our discussion on aphasias for our Lesson of the Week. Over the subsequent two weeks, we will continue to highlight the disorders of language. The participants had nothing to disclose except Drs. Dimberg, Finkel, Overman, Espay and Josephs. Dr. Dimberg serves as an editorial board member of AANEM Nerve and Muscle Junction Podcasts and as part of the Neurology® Podcast Panel, has received honoraria from ePocrates.com and Harris Interactive. Dr. Finkel serves on advisory boards for PTC Therapeutics, Inc., DuchenneConnect, Families of SMA, the National Fabry Disease Foundation, and TREAT-NMD; has received travel expenses for lectures not funded by industry; receives research support from PTC Therapeutics, Inc., Genzyme Corporation, Santhera Pharmaceuticals, the NIH (U54 AR0526446-03 [Co-I] and 1U54 NS0657-12-01 [Co-I]), the SMA Foundation, the Muscular Dystrophy Association, and the Foundation for the Eradication of Duchenne; and his spouse serves on the editorial board of Arthritis Research and Therapy, holds and has received license fees for numerous patents related to T cell activation and HIV, and receives research support from Merck Serono and the NIH in the field of T cell activation, HIV and genomics of juvenile arthritis.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Dr. Josephs is funded by R01- DC010367 (PI), the Dana Foundation (PI), and the Morris K. Udall PD Research Center of Excellence NIH/NINDS P50 NS40256 (Co-I).

1) Depression in Parkinson disease and 2) Topic of the month: Aphasia. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Russ Swerdlow interviews Dr. Massimo Filippi about his paper on depression in Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about five clues to the diagnosis of inclusion body myositis...and...amphiphysin antibody-associated stiff-person syndrome. In the next part of the podcast Dr. Alberto Espay interviews Dr. Keith Josephs about post-stroke aphasias for our Lesson of the Week. Over the next subsequent three weeks, we will highlight primary progressive aphasias. The participants had nothing to disclose except Drs. Filippi, Overman, Espay and Josephs. Dr. Filippi serves on scientific advisory boards for Teva Pharmaceutical Industries Ltd. and Genmab A/S; has received funding for travel from Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, and Teva Pharmaceutical Industries Ltd.; serves on editorial boards of the American Journal of Neuroradiology, BMC Musculoskeletal Disorders, Clinical Neurology and Neurosurgery, Erciyes Medical Journal, Journal of Neuroimaging, Journal of Neurology Neurosurgery and Psychiatry, Journal of Neurovirology, Magnetic Resonance Imaging, Multiple Sclerosis, and Neurological Sciences; serves as a consultant to Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, Pepgen Corporation, and Teva Pharmaceutical Industries Ltd.; serves on speakers' bureaus for Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, and Teva Pharmaceutical Industries Ltd.; and receives research support from Bayer Schering Pharma, Biogen-Dompe AG, Genmab A/S, Merck-Serono, Teva Pharmaceutical Industries Ltd., Fondazione Italiana Sclerosi Multipla, and Fondazione Mariani. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis. Dr. Josephs is funded by R01- DC010367 (PI), the Dana Foundation (PI), and the Morris K. Udall PD Research Center of Excellence NIH/NINDS P50 NS40256 (Co-I).

1) Seasonal prevalence of MS and 2) New Clinical Practice Journal. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Scagnelli interviews Dr. Dominik Meier about his paper on MS disease activity. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about drug-induced parkinsonism...and...alteplase-associated hemi?orolingual angioedema from the e-Pearl archives. In the next part of the podcast Dr. Ted Burns interviews Dr. John Corboy about the first issue of the new Clinical Practice Journal for our Lesson of the Week. The participants had nothing to disclose except Drs. Meier, Overman, Burns and Corboy. Dr. Meier has received research support from the NIH (R01 AG022092-01 [co investigator] and NCRR P41 RR013218 [consultant]. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Corboy serves as Editor for Clinical Practice Journal and Section Editor for Neurology Today, receives research support from Novartis [CFTY720D2309], the NIH [ NINDS1UO1NS4571901A1], and National MS Society and gave expert testimony in the trial of Colorado Anthony vs Loop, Morgan County District Court. A fixed 25 % of his salary is paid by the Rocky Mountain MS Center.

1) Cerebral artery infarctions 2) Antibiotics-cause of encephalopathy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Justin Sattin interviews Dr. Adam Kelly about his paper on cerebral artery infarctions. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about highlights from the e-Pearl archive. In the next part of the podcast Dr. Matthew Flaherty interviews Dr. Steven Lewis on antibiotics as a cause of encephalopathy for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Overman, Flaherty and Lewis.

1) Nonfluent primary progressive aphasia and 2) MuSK antibodies. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Farrah Mateen interviews Dr. Jonathan Rohrer about his paper on nonfluent primary progressive aphasia. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about the Stransky sign. In the next part of the podcast Dr. Beau Bruce interviews Dr. Donald Sanders about MuSK antibodies for our Lesson of the Week. The participants had nothing to disclose except Drs. Rohrer, Mateen, Overman, Bruce and Sanders. Dr. Mateen has received grant funding from the AAN/AANF 2010 Practice Research Fellowship. Dr. Rohrer has received research support from the Wellcome Trust (Clinical Research Fellowship) and Brain (Exit Scholarship).Dr. Overman serves as Deputy Editor on the Neurology(R) Resident and Fellow Section editorial team and the Neurology(R) Podcast Committee.Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.Dr. Sanders is a consultant for Accordant Health Services, Inc, Bayhill Therapeutics, Inc, Jacobus Pharmaceutical Co., Inc, BioMarin, Inc, Baxter International Inc., CytoKinetics, GlaxoSmithKline, and GTC Biotherapeutics, Inc, receives royalties from the publication of the book Single Fiber EMG and serves on the speakers' bureau of Athena Diagnostics and Talecris Biotherapeutics.

1) Comparative effectiveness research and 2) ACGME proposals for work duty hours. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Michael Benatar interviews Dr. Jacqueline French about her paper on comparative effectiveness research. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barré-like syndrome with thallium poisoning. In the next part of the podcast Dr. Ted Burns interviews Dr. Lori Schuh about ACGME recommendations for work duty hours for our Lesson of the Week. The participants had nothing to disclose except Drs. French, Overman, and Burns. Dr. French has served on scientific advisory boards for UCB, Johnson & Johnson, Eisai Inc., Novartis, Valeant Pharmaceuticals International, Icagen, Inc., Ikano Therapeutics Inc., Sepracor Inc., and Marinus Pharmaceuticals, Inc.; has received funding for travel from UCB, Kyowa Hakko Kirin Pharma, Inc., Eisai Inc., Johnson & Johnson, Valeant Pharmaceuticals International, and GlaxoSmithKline; serves as an Associate Editor of Epilepsy Currents and Supplement Editor for Epileptic Disorders; estimates that 30% of her time is spent in outpatient epilepsy practice; receives research support from the Epilepsy Therapy Development Project, FACES, Johnson & Johnson, Eisai Inc., UCB, SK Bio-Pharmaceuticals, Valeant Pharmaceuticals International, Vertex Pharmaceuticals, Pfizer Inc, Merck Serono, the NIH (R01 NS053998-01A1 [coinvestigator]), and from the Epilepsy Research Foundation; and serves as President of the Epilepsy Study Consortium, which receives money from multiple pharmaceutical companies. A fixed 20% of her NYU salary is paid by the study consortium, some of which may come from consulting fees from GlaxoSmithKline, Pfizer Inc, UCB, Johnson & Johnson, Cyberonics, Inc., SCHWARZ PHARMA, Ortho-McNeil-Janssen Pharmaceuticals, Inc., Eisai Inc., Jazz Pharmaceuticals, Ovation Pharmaceuticals, Endo Pharmaceuticals, Bial Pharmaceuticals, NeuroVista Corporation, Valeant Pharmaceuticals International, Icagen, Inc., Supernus Pharmaceuticals, Inc., Ikano Therapeutics Inc., SK Bio-Pharmaceuticals, TaroPharma, NeuroTherapeutics Pharma, Inc., Sepracor Inc., and Novartis. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Acute progressive neurologic decline and absence of mass lesion and 2) AAN.com and community features it provides. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Karen Roos interviews Drs. Jason Taub and Jeffrey Olson about their paper on acute progressive neurologic decline. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about unilateral photophobia or phonophobia in cluster headache. In the next part of the podcast Dr. Ted Burns interviews Dr. Daniel Hoch and Jose Merino about AAN.com and the community features it provides for our Lesson of the Week. The participants had nothing to disclose except Drs. Roos, Olson, Overman, Burns, Hoch, and Jose Merino. Dr. Roos serves as Editor-in-Chief of Seminars in Neurology, received royalties for 4 published textbooks, received funding for traveling from the AAN and other universities, and gave expert testimony, but monies received were forwarded to the Department of Neurology, Indiana University School of Medicine.Dr. Olson serves on the Data Safety Monitoring Board for Monteris, Inc., and has funded clinical research for which he is the Emory PI by Wyeth, Myriad Genetics, Inc., and Baxter International Inc.; and receives research support from the NIH (UO1CA137433-01 [Site PI], R01 CA116174 [Co-I], R01 CA121320-01 [Co-I], and R21 CA141836 [PI]).Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Hoch serves as an editorial board member of AAN.com, holds stock options in Merck Serono and Biogen Idec, and gave expert testimony in the trial for the State of Massachusetts, Essex County, 2008-2010.Jose Merino receives a stipend as Associate Editor for AAN.com, serves as an editorial board member of Stroke and receives salary support from NINDS contract with Suburban Hospital.

1) Multiple sclerosis: A meta-analytic approach 2) Ultrasound of peripheral nerves (Part 2). This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Mark Keegan interviews Dr. Maria Pia Sormani about her paper on multiple sclerosis: A meta-analytic approach. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about Terson syndrome. In the next part of the podcast Dr. Mary Lussier interviews Dr. Michael Cartwright for part two on peripheral nerve ultrasound for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Sormani, Keegan, Fugate, and Cartwright.

1) Mild cognitive decline 2) Ultrasound of peripheral nerves (Part 1). This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Susan Landau about her paper on mild cognitive decline. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about Doi's sign. In the next part of the podcast Dr. Mary Lussier interviews Dr. Michael Cartwright for part one on peripheral nerve ultrasound for our Lesson of the Week. The participants had nothing to disclose except Drs. Landau, Fugate, and Cartwright. Dr. Landau receives research support from the NIH (U01 AG024904 [Research specialist]).Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Cartwright receives research support from the NIH (1K23 N5062892-01A1) and has received speaker honoraria from AANEM and ASN annual meetings.

In this special podcast for the Neurology Journal, Dr. Ted M. Burns plays a dozen of the many interesting audio clips from Neurology Podcasts of the 2009-2010 academic year.

1) Diagnosis of acute ischemic stroke and 2) evidence-based medicine (Part 3). This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Peter Schellinger about his paper on diagnosis of acute ischemic stroke. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about digiti quinti sign. In the next part of the podcast Dr. Michael Benatar interviews Dr. Mark Conaway for part three on evidence-based medicine probability, odds, and odds ratio for our Lesson of the Week. The participants had nothing to disclose except Drs. Kissela, Schellinger and Fugate. Dr. Kissela served on the scientific advisory board for Allergan, Inc in 2009; served as a consultant for Allergan for 2-day meeting in 2009; received honoraria from CME program and unrestricted educational grants; received research support from the NIH [R01 NS 30678], [N01 NS 081588], [1Ul1 RR026314] and received compensation for reviewing records for several medical/legal cases regarding stroke.Dr. Schellinger has served/serves on scientific advisory boards for Boehringer Ingelheim, ImaRx Therapeutics, Photothera, Cerevast, and CoAxia, Inc.; has served/serves on speakers' bureaus for and received funding for travel and speaker honoraria from Boehringer Ingelheim, Sanofi, ImaRx Therapeutics, Photothera, Cerevast, CoAxia, Inc., Solvay Pharmaceuticals, Inc., and GlaxoSmithKline; serves on editorial boards of Stroke and European Neurology; receives royalties from the publication of NeuroIntensiv (Springer, 2008) and received royalties from the publication of Stroke MRI (Steinkopff, 2004); has served as a consultant for CoAxia, Inc., Photothera, Cerevast, ImaRx, and Boehringer Ingelheim; and has provided expert testimony, affidavits, and acted as a witness or consultant in legal proceedings.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section.

1) Depressive symptoms and risk of dementia and 2) Early history of the AAN. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. David Geldmacher interviews Dr. Jane Saczynski about her paper on depressive symptoms and risk of dementia. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about wrong way eyes. In the next part of the podcast Dr. Ted Burns interviews Dr. Robert Joynt on the early history of the AAN for our Lesson of the Week. The participants had nothing to disclose except Drs. Fugate, Burns and Joynt. Dr. Geldmacher serves on editorial board of Brain Injury, has received speaker honoraria from Danville Regional Medical Center, Georgetown Medical School, University of Rochester, Cleveland Clinic, Kaiser Permanante and Academy for Healthcare Education, receives research support from Elan Corporation [PI], Eisai Inc. [PI], Medivation, Inc. [PI], Janssen [PI] and Novartis [PI].Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Joynt receives a stipend as Newsletter Editor for Neurology® and royalties from Archives of Neurology for published work.

1) Imaging in acute stroke and 2) conflicts of interest: A personal perspective. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Yves Samson about his paper on diffusion-weighted MR imaging in acute stroke. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about posterior vermal split syndrome. In the next part of the podcast Dr. Matthew Wong interviews Dr. Joseph Martin for our Lesson of the Week about his paper on the pervasive influence of conflicts of interest. The participants had nothing to disclose except Drs. Kissela, Samson and Martin. Dr. Kissela served on the scientific advisory board for Allergan, Inc in 2009; served as a consultant for Allergan for 2-day meeting in 2009; received honoraria from CME program and unrestricted educational grants; received research support from the NIH [R01 NS 30678], [N01 NS 081588], [1Ul1 RR026314] and received compensation for reviewing records for several medical/legal cases regarding stroke. Dr. Samson is co-inventor of Neurinfarct software (Patent WO 2008/000973, issued 2008) currently owned by Intelligence in Medical Technologies, Paris; and holds stock in Intelligence in Medical Technologies. Dr. Martin has been on the Board of Directors at Baxter International for 8 years. For a short narrative describing this activity in greater detail, and the effect it had on Dr. Martin's activities, please see appendix e-1 at www.neurology.org

1) Restless legs syndrome and 2) evidence-based medicine (part 2). This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Aman Savani interviews Dr. Diego Garcia-Borreguero about his paper on restless legs syndrome. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about fatal gastroenteritis. In the next part of the podcast Dr. Michael Benatar interviews Dr. Mark Conaway for part two on evidence-based medicine relative risk, relative risk reduction, absolute risk reduction, and NNT for our Lesson of the Week. You may also want to check out the other two-part series on evidence-based medicine where Dr. Michael Benatar interviewed Dr. Gary Gronseth for our March 30 and April 6 Lesson of the Week. The participants had nothing to disclose except Dr. Garcia-Borreguero. Dr. Garcia-Borreguero has served on scientific advisory boards for and received speaker honoraria from Boehringer Ingelheim, GlaxoSmithKline, UCB, Pfizer Inc, XenoPort, Inc., sanofi-aventis, Jazz Pharmaceuticals, and Merck & Co., Inc.

1) Embouchure dystonia and 2) progressive myoclonic encephalopathies. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Robert Pascuzzi interviews Dr. Bernhard Haslinger about his paper on embouchure dystonia. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about the corneal reflex in stroke. In the next part of the podcast Dr. Alberto Espay interviews Dr. Berge Minassian for part 2 on progressive myoclonic encephalopathies for our Lesson of the Week. The participants had nothing to disclose except Drs. Haslinger, Pascuzzi and Espay. Dr. Haslinger serves on a scientific board for Merz Pharmaceuticals, LLC; has received funding from travel from Ipsen, Merz Pharmaceuticals, LLC, and Medtronic, Inc.; has received speaker honoraria from Novartis, GlaxoSmithKline, Desitin Pharmaceuticals, GmbH, Ipsen, and Allergan, Inc.; receives research support from Ipsen and from the German Research Foundation (DFG).Dr. Pascuzzi serves on the Board of Directors of the ABPN; serves on the Neurology RRC; served as immediate past Program Director for Neurology Residency Training at Indiana University; participates in multicenter clinical trials for a variety of neuromuscular disorders but receives no direct compensation; and gives lectures for the AAN and at multiple academic medical centers but does not received personal compensation.Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.

1) Guillain-Barré syndrome vs. CIDP and 2) progressive myoclonic encephalopathies. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Erik Ensrud interviews Dr. Pieter van Doorn about his paper on Guillain-Barré syndrome. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Harlequin syndrome. In the next part of the podcast Dr. Alberto Espay interviews Dr. Berge Minassian for part 1 on progressive myoclonic encephalopathies for our Lesson of the Week. The participants had nothing to disclose except Drs. van Doorn and Espay.Dr. van Doorn receives research support from the Prinses Beatrix Fonds, the GBS-CIDP Foundation International and from Baxter biopharmaceutics.Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.

Frontotemporal dementia and advocacy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Eneida Mioshi about her paper on frontotemporal dementia. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about atypical unilateral severe facial pain in smokers. In the next part of the podcast Dr. Ted Burns interviews Dr. Robert Griggs on advocacy for our Lesson of the Week. The participants had nothing to disclose except Drs. Mioshi, Burns and Griggs.Dr. Mioshi serves on the editorial board of Dementia and Geriatric Cognitive DisordersDr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Griggs serves on the editorial advisory board for Current Treatment Options in Neurology and NeuroRX; has received honoraria for lectures or educational activities not funded by industry; receives research support from the NINDS T32 NS07338 [PI]; NIH 2U54 NS059065-06 [PI], R01 NS045686-05 [PI], NIH-R13 Fostering Pharma, NINDS 525326 FOR-DMD, and FDA 2-RO1FD003454-02 [Co-PI] and TaroPharma; receives funding support from MDA Fostering Pharma-Academic Partnerships in Neuromuscular Experimental Therapeutics, Muscular Dystrophy Association Experimental Therapeutics of Neuromuscular Disease and Recruitment for HYP HOP Phase III trial in the Periodic paralyses (PI); and receives royalties from the publication of the book, Cecil Textbook of Medicine, 23 Edition.