Neurology® Podcast

In the first interview, Dr. Teshamae Monteith talks with Dr. Francesca Puledda about her paper on clinical and phenotypical descriptions of visual snow syndrome patients. In the second interview, Dr. Jason Crowell talks with Ed Silverman about the settlement over allegations a patient charity helped drug makers pay kickbacks to Medicare patients over MS drugs. You can read the STAT article here: https://www.statnews.com/2019/11/20/patient-charity-allegations-ms-drug-makers-kickbacks/.

In the first segment, Dr. Jason Crowell talks with Dr. Timothy Yu about patient-customized oligonucleotide therapy for a rare genetic disease. In the second part of the podcast, Dr. Jeffrey Burns talks with Dr. Amy Sanders about her implementation update on quality improvement in dementia care. You can read Dr. Yu's paper in the NEJM: https://www.nejm.org/doi/full/10.1056/NEJMoa1813279. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

This month's Delayed Recall highlights episodes on CTE and head trauma. Dr. Jason Crowell talks with Dr. Jesse Mez on his work on chronic traumatic encephalopathy and American football players, from the August 29, 2017. The next segment, from January 21, 2020, features Dr. Jeff Ratliff interviewing Dr. Charles Bernick on MRI biomarkers in boxers and MMA fighters. Next, from April 3, 2018, Dr. Lee Goldstein discusses teen concussion and early tauopathy with Dr. Jeff Ratliff. Finally, we feature the November 6, 2012 interview between Dr. Jeff Kutcher and Dr. Everett Lehman about his paper on NFL players and neurologic causes of death.

Dr. Jason Crowell talks with Dr. Daniel Hartung about his qualitative study on drug prices for MS.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Charles Bernick about his paper on longitudinal change in regional brain volumes with exposure to repetitive head impacts. In the second part of the podcast, Dr. Teshamae Monteith talks with Dr. Amy Gelfand about infant colic and episodic syndromes. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy talks with Dr. Francesc Graus and Dr. Josep Dalmau about their paper on Hashimoto encephalopathy in the 21st century. In the second part of the podcast, Dr. Teshamae Monteith talks with Dr. Richard Lipton and Dr. Dawn Buse about migraine progression in subgroups of migraine based on comorbidities.

Dr. Michelle Mauermann talks with Dr. Mary Reilly about her paper on targeted, next-generation, sequencing panels in the diagnosis of Charcot-Marie-Tooth disease.

This month's Delayed Recall highlights episodes from Nobel Prize winners. Dr. Jason Crowell talks with Dr. Stanley Prusiner on his work, from the October 15th and 22nd, 2019, episodes. The next segment, from December 17th, features Dr. Peter Doherty.

Dr. Ted Burns, creator and former editor of the Neurology Podcast, discusses the history, process, and meaning of the podcast.

This week, we feature past interviews with Dr. Mike Wilson on metagenomics.

Dr. Stacey Clardy talks with Nobel Laureate Peter Doherty about his collaborative work with Rolf Zinkernagel regarding how the body's immune system distinguishes virus-infected cells from normal cells, among many other topics.

In the first segment, Dr. Jason Crowell talks with Dr. Casey Halpern about his paper on a three-year follow-up of a prospective trial of focused ultrasound thalamotomy for essential tremor. In the second part of the podcast, Will Rondeau talks with Dr. Jared Chen and Dr. Andrew Southerland about statins for neuroprotection in spontaneous intracerebral hemorrhage. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Ted Burns talks with Dr. Stacey Clardy about neuromyelitis optica. In the second part of the podcast, Dr. Jason Crowell talks with Dr. Alberto Ascherio about his paper on physical activity and prodromal features of Parkinson disease. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

This month's Delayed Recall highlights episodes on the life of Oliver Sacks. Dr. Ted Burns and Oliver Sacks start the show discussing Sacks' life and experiences as a patient, which first aired in 2010. The next segments, from October 28th and November 4th, 2019, feature Lawrence Weschler, Dr. Sacks' biographer, discussing the life of the neurologist.

Dr. Stacey Clardy talks with Dr. Sylvia Tenembaum about her paper on prognostic indicators of improvement with therapeutic plasma exchange in pediatric demyelination.

In the first segment, Dr. Jason Crowell talks with Dr. Joel Salinas about his editorial on neurologists' duty to treat social ills. In the second part of the podcast, Dr. Teshamae Monteith talks with Dr. Andrew Hershey about his practice guideline update summary paper in Neurology® on pharmacologic treatment for pediatric migraine prevention. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy continues her talk with Dr. Lawrence Weschler about his book on Oliver Sacks, And How are You, Dr. Sacks?, in the second of a two-part interview. In the second part of the podcast, Dr. Stacey Clardy talks with Dr. Andrew Mammen about his paper on more prominent muscle involvement in dermatomyositis patients with anti-Mi2 autoantibodies.

This month's Delayed Recall highlights episodes on CRISPR gene editing technologies. From February 2017, we have an introduction to CRISPR. Then, there's a 2-part interview with Dr. Kevin Esvelt from February 20 and 27, 2018, on gene drives.

In the first segment, Dr. Stacey Clardy talks with Dr. Richard Burt about his paper on autologous, nonmyeloablative hematopoietic stem-cell transplantation for neuromyelitis optica. In the second part of the podcast, Dr. Stacey Clardy speaks with Dr. Lawrence Weschler about his book on Oliver Sacks, And How are You, Dr. Sacks?, in the first of a two-part interview. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Jeff Burns talks with Dr. Randall Bateman about his paper addressing how high precision plasma amyloid-β 42/40 predicts current and future brain amyloidosis. In the second part of the podcast, you'll hear the second part of an interview with Nobel Prize winner Dr. Stanley H. Prusiner. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Ylva Hiorth and about their paper on a 7-year prospective population-based study on orthostatic hypotension in Parkinson disease. In the second part of the podcast, Dr. Jason Crowell talks with Nobel Prize winner Dr. Stanley B. Prusiner in the first part of a two-part interview. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Greg Day talks with Dr. Kiran Thakur and Dr. Greer Waldrop about their paper on diagnostics for neurologic disorders on the World Health Organization's essential diagnostic list. In the second part of the podcast, Dr. Stacey Clardy speaks with Dr. Sean Pittock on his NEJM paper on eculizumab in aquaporin-4–positive neuromyelitis optica spectrum disorder. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

This month's Delayed Recall highlights episodes on drug pricing controversies. Dr. Jason Crowell and Professor Robin Feldman start the show discussing "evergreening" and drug prices, which first aired on August 20th, 2019. The next segments, from September 17th and 24th, has Dr. Gordon Smith and Dr. Steve Pearson discussing updates to drug pricing in a follow-up to their earlier talk on the subject. Following this segment is one from May 27th and finds Dr. Jason Crowell talking with Dr. Brian Callaghan about rising out-of-pocket costs for commonly prescribed neurologic medications. This episode concludes with an interview on with Dr. Jason Crowell and Politico reporters Sarah Karlin-Smith and Sarah Owermohle.

In the first segment, Dr. Jason Crowell talks with Dr. Emma Ciafaloni about her clinical/scientific note on combination therapy with nusinersen and AVXS-101 in SMA type 1. In the second part of the podcast, Dr. Jason Crowell speaks with Dr. Douglas Smith on neuroimaging findings in US government personnel with possible exposure to directional phenomena in Havana, Cuba. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy talks with Dr. Mauricio Farez about his practice guideline update summary on vaccine-preventable infections and immunization in multiple sclerosis. In the second part of the podcast, Dr. Gordon Smith continues his discussion with Dr. Steve Pearson on an update on drug pricing. Their previous discussion on drug pricing was featured in two parts on January 8th and January 15th, 2019. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy talks with Dr. Julie Silver about her paper on understanding and addressing gender equity for women in neurology. In the second part of the podcast, Dr. Gordon Smith focuses his discussion with Dr. Steve Pearson on an update on drug pricing. Their previous discussion on drug pricing was featured in two parts on January 8th and January 15th, 2019. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Noah Kolb talks with Dr. Amanda Guidon about her paper on varied phenotypes and management of immune checkpoint inhibitor associated neuropathies. In the second part of the podcast, Dr. Stacey Clardy focuses her discussion with Dr. Mike R. Wilson on clinical metagenomic sequencing for diagnosis of meningitis and encephalitis. Read the full NEJM article here: https://www.nejm.org/doi/full/10.1056/NEJMoa1803396. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

This month's Delayed Recall highlights interviews with some of the plenary session speakers from this year's AAN Annual Meeting. We highlight talks with Dr. Jonathan Mink, Dr. Claudia Lucchinetti, Dr. Jed Hartings, Dr. Ronald Melki, and Dr. J. Paul Taylor.

In the first segment, Dr. Alex Menze talks with Dr. Jonathan Newmark about his Neurology: Clinical Practice paper that provides an update on therapy for acute nerve agent poisoning. In the second part of the podcast, Dr. Andrew Schomer focuses his discussion with Dr. Jan Claassen on detection of brain activation in unresponsive patients with acute brain injury. Read the full NEJM article here: https://www.nejm.org/doi/full/10.1056/NEJMoa1812757. Information on managing nerve agent attack can be found here: https://ccc.apgea.army.mil/. Disclosures can be found at Neurology.org. No CME this week: Interviews based on articles from Neurology® Clinical Practice, Neurology® Genetics, and Neurology® Neuroimmunology & Neuroinflammation are excluded from the CME program.

Dr. Stacey Clardy focuses her discussion with Dr. Amanda Grennell on an update on Zika for 2019. Read the full article here: https://www.nature.com/articles/d41586-019-01906-z.

In the first segment, Dr. Stacey Clardy talks with Dr. Anastasia Zekeridou about her paper on Phosphodiesterase 10A-IgG, a novel biomarker of paraneoplastic neurological autoimmunity. In the second part of the podcast, Dr. Jason Crowell focuses his discussion with Prof. Robin Feldman on "evergreening" and drug prices. Read the full article here: https://www.nature.com/articles/d41586-019-01906-z. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Jason Crowell talks with Dr. Michele Hu and Dr. David Okai about their longitudinal study of the severity of impulse control disorders in Parkinson disease and RBD. In the second part of the podcast, Dr. Jason Crowell focuses his discussion with Dr. Heidi Ledford on her Nature article discussing CRISPR babies and what would be required to make gene editing safe and acceptable. Read the full article here: https://www.nature.com/articles/d41586-019-01906-z. Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy talks with Dr. Robert Zivadinov about cumulative gadodiamide administration leading to brain gadolinium deposition in early MS. In the second part of the podcast, Dr. Jeffrey Ratliff focuses his discussion with Dr. Michael D. Fox on his Brain paper on network localization of cervical dystonia based on causal brain lesions. You can read the paper here: https://academic.oup.com/brain/article-abstract/142/6/1660/5491101?redirectedFrom=fulltext.

This month's Delayed Recall highlights more interviews from our new podcast offering, Neurology Minute. In 2019, Neurology launched a new podcast perfect for Alexa and other similar devices. This episode features digestible "minutes" from June and July. See the instructions for enabling the Neurology Minute on Amazon Alexa below:

In the first segment, Dr. Kristen Heinan talks with Dr. Barbara Weissman about her Neurology: Clinical Practice paper on recommendations for neurologists on the CDC's Guideline on Pediatric Mild Traumatic Brain Injury. In the second part of the podcast, Dr. Will Rondeau focuses his discussion with Dr. Geoffrey Donnan on his NEJM paper on thrombolysis guided by perfusion Imaging up to 9 hours after onset of stroke. You can read the paper here: https://www.nejm.org/doi/pdf/10.1056/NEJMoa1813046.

In the first segment, Dr. Gregory Day talks with Dr. Philip Insel about his paper on determining clinically meaningful decline in preclinical Alzheimer disease. In the second part of the podcast, Dr. Sarah Tabrizi talks about targeting Huntington expression in patients with Huntington's disease in her interview with Dr. Jeffrey Ratliff. Read Dr. Tabrizi's paper in NEJM: https://www.nejm.org/doi/full/10.1056/NEJMoa1900907?query=recirc_curatedRelated_article.

In the first segment, Dr. Halley Alexander talks with Dr. Orrin Devinsky about his paper on the full spectrum of epilepsies and the North American SUDEP Registry. In the second part of the podcast, Dr. Ted Burns focuses his discussion with Dr. Gil Wolfe on his Lancet Neurology paper on the long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis. You can read the paper here: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(18)30392-2/fulltext.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Franziska Hopfner about her paper on the use of ß2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease. In the second part of the podcast, Dr. Jason Crowell focuses his discussion with Dr. Jerzy Szaflarski on his JAMA Neurology paper on the US Food and Drug Administration's authorization of the first cannabis-derived pharmaceutical. You can read the paper here: https://jamanetwork.com/journals/jamaneurology/article-abstract/2714720.

In the first segment, Dr. Michelle Mauermann talks with Dr. Bart Jacobs about his paper on current treatment practice of Guillain-Barré syndrome. In the second part of the podcast, Dr. Matthew Harms focuses his discussion with Dr. Guy Rouleau on his Neurology: Genetics paper looking at how somatic expansion of the C9orf72 Hexanucleotide Repeat does not occur in ALS spinal cord tissues.

This month's Delayed Recall highlights interviews on epilepsy and EEG. Dr. Derek Bauer talks with Dr. Paula Emanuela Voinescu about her paper on antiepileptic drug clearances during pregnancy and the relationship between drug serum concentration and seizure frequency from the Sept 25, 2018, podcast. Next, Dr. Andy Schomer talks with Dr. Chloe Hill on the association between continuous EEG and favorable hospitalization outcomes for critically ill patients from the January 1, 2019, podcast. For the next segment, we're back with Derek Bauer, this time talking with Dr. Jacqueline French about the recent practice guideline on the treatment of new-onset epilepsy from the July 10, 2018 episode. And then again from the April 2, 2019, podcast, we hear Derek Bauer talk with Dr. Stephan Schuele about his paper on automated seizure detection accuracy for ambulatory EEG recordings. Finally, we wrap up with Jeff Ratliff talking to Dr. Anup Patel about the 2017 epilepsy quality measurement set update, which originally aired on the October 30, 2018, podcast.

In the second part of a 2-part interview, Dr. Bob Gross discusses changes to the journal and publishing as well as some controversies and challenges as Editor-in-Chief of Neurology.

In the first part of a 2-part interview, Dr. Bob Gross discusses his experiences, opportunities, and challenges as Editor-in-Chief of Neurology.

Dr. Stacey Clardy talks with Dr. P. James B. Dyck about his paper on the incidence of lumbrosacral radiculoplexus neuropathy and association with diabetes mellitus.

Dr. Jason Crowell focuses his talk with Dr. Deborah Dowell on her NEJM perspective article looking at opioid prescribing and response to the CDC guidelines. You can read Dr. Dowell's paper here: https://www.nejm.org/doi/full/10.1056/NEJMp1904190.

This month's Delayed Recall highlights interviews from our new podcast offering, Neurology Minute. In 2019, Neurology launched a new podcast perfect for Alexa and other similar devices. This episode features digestible "minutes" on measles in 2019, gene editing, the SHINE stroke trial, and more.

In the first segment, Dr. Jason Crowell talks with Dr. Brian Callaghan about rising out-of-pocket costs for commonly prescribed neurologic medications. In the second part of the podcast, Dr. Jeffrey Ratliff focuses his interview with Dr. Stefan Pulst on ataxias. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

In the first segment, Dr. Stacey Clardy talks with Dr. Annie Lannuzel about the importance of biological diagnosis in long-term outcome in neuroZika. In the second part of the podcast, Dr. Will Rondeau focuses his interview with Dr. Stuart Connolly on his NEJM paper on the full study report of andexanet alfa for bleeding associated with factor Xa inhibitors. The paper can be found here: https://www.nejm.org/doi/full/10.1056/NEJMoa1814051. CME Opportunity: Listen to this week's Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

This month's Delayed Recall highlights episodes on developments and scandals related to genetic testing and technology in neurology. Dr. Jason Crowell and Dr. Josephine Johnston of the Hastings Center start the show discussing the ethical and philosophical implications of gene editing., which first aired on December 18th, 2018. The next segment, also from December 18th, has Dr. Stacey Clardy and Dr. Stefan Pulst focusing on the scientific and societal impact of the recent first reported gene editing using the CRISPR technology. Following this segment is one from December 3rd and finds Dr. Jeff Waugh talking with Dr. Saadet Andrews about her paper on the genetic landscape of pediatric movement disorders and management implications. This episode continues with an interview on a Neurology: Genetics on the long journey to diagnosis for patients with mitochondrial disease between Dr. Jason Crowell and Drs. John L.P. Thompson and Michio Hirano from April 3rd, 2018. The episode wraps up with a talk between Dr. Jeffrey Ratliff and Dr. Thomas Bird from March 20th, 2018, on Dr. Bird's Neurology: Clinical Practice paper on the benefits and limitations of exome sequencing to identify hereditary ataxias.

In the first segment, Dr. Lindsay Higdon talks with Dr. Ivan Sanchez Fernandez about his paper on the meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus. In the second part of the podcast, Dr. Stacey Clardy talks with Dr. Anthony Fauci about the measles outbreak of 2019. You can read the paper in NEJM: https://www.nejm.org/doi/full/10.1056/NEJMp1905099.

In the first segment, Dr. Jeffrey Ratliff talks with Dr. Tamara Milka Pringsheim about her practice guideline recommendations summary paper on the treatment of tics in people with Tourette syndrome and chronic tic disorders. In the What's Trending segment, you'll hear the second part of an interview between Dr. Jason Crowell and New York Times staff writer Pam Belluck on CRISPR and gene editing.