Neurology Minute
1,924 episodes — Page 9 of 39
Genetic Leukodystrophies Mimicking CNS Inflammation - Part 2
In part two of this three-part series, Dr. Justin Abbatemarco and Dr. Jennifer L. Orthmann Murphy discuss practical approaches to genetic adrenoleukodystrophy. Show references: https://www.neurology.org/doi/10.1212/NXG.0000000000200192
Genetic Leukodystrophies Mimicking CNS Inflammation - Part 1
In the first part of this three-part series, Dr. Justin Abbatemarco and Dr. Jennifer L. Orthmann Murphy discuss red flag symptoms that suggest the need for genetic testing in patients with white matter disease. Show references: https://www.neurology.org/doi/10.1212/NXG.0000000000200192 https://cshperspectives.cshlp.org/content/early/2024/08/10/cshperspect.a041457
Early Treatment Cuts Relapse Risk in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease
Dr. Rae Bacharach discusses the Neurology Today article, "Early Treatment Cuts Relapse Risk in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease," by Gina Shaw, available in the latest issue of Neurology Today or at neurologytoday.com. Show reference: https://journals.lww.com/neurotodayonline/pages/default.aspx https://jamanetwork.com/journals/jamaneurology/article-abstract/2822964
Interventions for the Acute Management of Migraine Episodes in Adults - Part 3
In the final part of this three-part series, Drs. Tesha Monteith, Messoud Ashina, and Andrea Cipriani discuss what you need to know about analyzing network meta-analysis. Show reference: https://www.bmj.com/content/386/bmj-2024-080107
Eculizumab Use in Neuromyelitis Optica Spectrum Disorders
Drs. Justin Abbatemarco, Marius Ringelstein, and Ilya Ayzenberg discuss a new class of complement inhibitors that we're using in NMOSD. Show reference: https://www.neurology.org/doi/full/10.1212/WNL.0000000000209888
Interventions for the Acute Management of Migraine Episodes in Adults - Part 2
In part two of this three-part series, Drs. Tesha Monteith, Messoud Ashina, and Andrea Cipriani discuss clinical pearls on how to select an acute treatment plan for migraine. Show reference: https://www.bmj.com/content/386/bmj-2024-080107
Interventions for the Acute Management of Migraine Episodes in Adults - Part 1
In the first part of this three-part series, Drs. Tesha Monteith, Messoud Ashina, and Andrea Cipriani explain the significance of this study and how its findings can be applied in clinical practice. Show reference: https://www.bmj.com/content/386/bmj-2024-080107
Timing of Anticoagulation Resumption and Risk of Ischemic and Hemorrhagic Complications in Patients With ICH and Mechanical Heart Valves
Dr. Jodie Roberts and Dr. Amra Sakusic discusses the relationship between reversal therapy and ischemic stroke, between duration off anticoagulation and risk of ischemic strokes or systemic embolism. Learn more about the Neurology Practice Current section and fill out the survey now. Show reference: https://survey.alchemer.com/s3/7969148/Practice-Current-When-do-you-start-anticoagulation-therapy-for-patients-with-both-ICH-and-AF https://www.neurology.org/doi/10.1212/WNL.0000000000209664
Women History Minute - The Women of the Cajal School
In this Women's History Minute, Dr. Alison Christy discusses the Cajal School of Neuropathology in Spain and emphasizes the importance of mentorship.
Revised Criteria for Diagnosis and Staging of Alzheimer Disease
Dr. Greg Cooper and Dr. Clifford R. Jack Jr. discuss objective criteria for diagnosis and staging Alzheimer disease, highlighting recent advancements in biomarkers to bridge the gap between research and clinical practice. Show reference: https://pubmed.ncbi.nlm.nih.gov/38934362/
End-of-Life Health Care Service Use and Cost
Dr. Gordon Smith and Dr. Whitley Aamodt discuss end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209925
Women History Minute - Cecile Vogt
Dr. Alison Christy delves into another women's history minute to discuss Cecile Vogt.
Neurology on the Hill
Dr. Jason Crowell talks about Neurology on the Hill and how you can get involved if you are interested. Show reference: https://www.aan.com/policy-and-guidelines/capitol-hill-report/
A Comparison of Side Effects for Four First-line Antiseizure Medications
Dr. Halley Alexander discusses the Neurology Today article, "A Comparison of Side Effects for Four First-line Antiseizure Medications" by Stacey Burling, available in the September 19th issue of Neurology Today or at neurologytoday.com. Show reference: https://journals.lww.com/neurotodayonline/fulltext/2024/09190/a_comparison_of_side_effects_for_four_first_line.1.aspx
Epilepsy in Patients With Primary CNS Lymphoma
Dr. Kait Nevel and Dr. Oumaima Aboubakr discuss the prevalence of epilepsy in primary CNS lymphoma. Show reference: https://www.neurology.org/doi/abs/10.1212/WNL.0000000000209748
The Rise of the Science Sleuths - Part 3
In the final part of this three-part series, Drs. Stacey Clardy, Elisabeth Bik, and Matthew Schrag discuss how to uphold research integrity. Show reference: https://undark.org/2024/09/11/the-rise-of-the-science-sleuths/
Lab Minute - B Vitamins
Dr. Stacey Clardy discusses why B vitamins matter in neurology in this lab minute.
Lab Minute - ACE levels
Dr. Stacey Clardy discusses what to check instead of ACE levels if you suspect a diagnosis of sarcoidosis in this lab minute.
How to Respond to a Request for Hastened Death from a Person Living with Neurologic Illness
Dr. Rae Bacharach talks with Dr. Manon Auffret about her NeuroByte titled, "How to Respond to a Request for Hastened Death from a Person Living with Neurologic Illness". Show reference: https://learning.aan.com/courses/74069
The Rise of the Science Sleuths - Part 2
In part two of this series, Drs. Stacey Clardy, Elisabeth Bik, and Matthew Schrag discuss the best ways that we as neurology clinicians and researchers can help to actively prevent fraud. Show references: https://undark.org/2024/09/11/the-rise-of-the-science-sleuths/
The Rise of the Science Sleuths - Part 1
In the first part of this special three-part series, Drs. Stacey Clardy, Elisabeth Bik, and Matthew Schrag discuss critical issues surrounding research integrity and misconduct. Show references: https://undark.org/2024/09/11/the-rise-of-the-science-sleuths/
Lab Minute - Thyroid Antibodies
Dr. Stacey Clardy discusses the four different testable thyroid antibodies. Show references: https://www.neurology.org/doi/10.1212/WNL.0000000000008785 https://academic.oup.com/braincomms/article/3/2/fcaa233/6064134
Lab Minute - IgG4
Dr. Stacey Clardy discusses how to test for IgG4-related disease and how to interpret MIR imaging findings. Show reference: https://ard.bmj.com/content/74/1/14a
Deep Brain Stimulation of Symptom-Specific Networks in Parkinson Disease - Part 2
Drs. Jeff Ratliff, Nanditha Rajamani, and Andy Horn discuss the potential for wider use of algorithmic or computational approaches to guide clinical DBS programming in the clinic and the remaining hurdles. Show reference: https://www.nature.com/articles/s41467-024-48731-1
Global Burden of Neurologic Conditions
Dr. Farrah Mateen and Dr. Katrin Seeher discuss the significant global burden of neurologic conditions, which affects over 3.4 billion people worldwide, and the strategies the WHO is implementing to improve care and awareness. Show reference: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00038-3/fulltext#seccestitle10
Deep Brain Stimulation of Symptom-Specific Networks in Parkinson Disease - Part 1
Drs. Jeff Ratliff, Nanditha Rajamani, and Andy Horn discuss what this study taught us about the use of deep brain stimulation when taking into account certain white matter tracts associated with key clinical Parkinson motor symptoms. Show reference: https://www.nature.com/articles/s41467-024-48731-1
Lab Minute - Iron
Dr. Stacey Clardy discusses the importance of iron and ferritin in neurology in this lab minute.
What Neurologist Should Know About Antidepressants, Weight Gain for Neuropathy
Dr. Rae Bacharach discusses the Neurology Today article, "What Neurologist Should Know About Antidepressants, Weight Gain for Neuropathy" by Gina Shaw, available in the September 19th issue of Neurology Today or at neurologytoday.com. Show reference: https://journals.lww.com/neurotodayonline/fulltext/2024/09190/what_neurologists_should_know_about.2.aspx#:~:text=Neurologists%20frequently%20prescribe%20antidepressants%20for%20managing%20neuropathy%20and,likely%20to%20become%20nonadherent%20to%20control%20their%20weight.
The Topic of Neurological Care for Transgender Patients - Part 3
In the final part of this three-part series, Dr. Halley Alexander and Dr. Gwen Zeigler discuss the management of epilepsy in transgender or gender diverse patients. Show reference: https://www.neurology.org/doi/abs/10.1212/CPJ.0000000000200332
Relapsing-Remitting Immunotherapy Responsive SFN
Dr. Shuvro Roy and Dr. Anne Louise Oaklander discuss the big-picture takeaways for clinicians in the context of managing small-fiber neuropathy. Show reference: https://www.neurology.org/doi/10.1212/NXI.0000000000200286
Gender Discrepancies in Leadership Roles and Recognition Awards in the Child Neurology Society
Dr. Dara Albert and Dr. Jaclyn M. Martindale discuss the differences in gender representation among leadership positions and award recipients within the Child Neurology Society. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209746
The Topic of Neurological Care for Transgender Patients - Part 2
In part two of this three-part series, Dr. Halley Alexander and Dr. Gwen Zeigler discuss cerebrovascular risk and management in transgender and gender-diverse patients. Show reference: https://www.neurology.org/doi/abs/10.1212/CPJ.0000000000200332
The Topic of Neurological Care for Transgender Patients - Part 1
In part one of this three-part series, Dr. Halley Alexander and Dr. Gwen Zeigler discuss the crucial aspects about managing headaches in transgender and gender-diverse patients. Show reference: https://www.neurology.org/doi/abs/10.1212/CPJ.0000000000200332
A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders - Part 2
In part two of this two-part series, Drs. Jeff Ratliff, Michiko K. Bruno, and Lawrence Golbe discuss essential advice for general neurologists who suspect a patient might have an atypical disorder. Show reference: https://www.neurology.org/doi/full/10.1212/CPJ.0000000000200345
A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders - Part 1
In part one of this two-part series, Drs. Jeff Ratliff, Michiko K. Bruno, and Lawrence Golbe discuss practical tips for recognizing when a patient's response to levodopa may indicate the need for an alternate diagnosis. Show reference: https://www.neurology.org/doi/full/10.1212/CPJ.0000000000200345
CMAP and Myosin-Loss Pathology in Patients With Critical Illness Myopathy
Drs. Gordon Smith, Shahar Shelly, and Teerin Liewluck discuss the correlation between CMAP duration and myosin loss and their effect on mortality by comparing between patients with CIM with and without myosin loss. Show references: https://www.neurology.org/doi/10.1212/WNL.0000000000209496
Improving Clinical Documentation Efficiency with AI
Dr. Irfan Sheikh explores a newly released NeuroByte episode, providing an insightful overview of how AI technologies, including ambient intelligence, can streamline documentation processes and enhance the efficiency of clinical practices. Show references: https://learning.aan.com/courses/74256
Monoclonal Antibody to PACAP for Migraine Prevention - Part 2
In the second installment of this two-part series, Dr. Tesha Monteith and Dr. Messoud Ashina discuss the results of the phase two study on monoclonal antibody to PACAP for migraine prevention. Show reference: https://www.nejm.org/doi/full/10.1056/NEJMoa2314577
Depression During Intern Year Increases Risk for Persistent MD Depression: What Can Training Programs Do to Intervene
Dr. Rae Bacharach discusses the Neurology Today article, "Depression During Intern Year Increases Risk for Persistent MD Depression: What Can Training Programs Do to Intervene?" by Gina Shaw, available in the September 5th issue of Neurology Today or at neurologytoday.com. Show reference: https://journals.lww.com/neurotodayonline/fulltext/2024/09050/large_study_finds_covid_vaccination_does_not.3.aspx
Monoclonal Antibody to PACAP for Migraine Prevention - Part 1
In the first installment of this two-part series, Dr. Tesha Monteith and Dr. Messoud Ashina explore the biology of PACAP, its significance in relation to migraines, and its potential as a novel therapeutic approach. Show reference: https://www.nejm.org/doi/full/10.1056/NEJMoa2314577
Association of Extent of TSS With Cerebral Glymphatic Clearance in Patients With IIH
Dr. Amy Gelfand and Dr. Matthew Bender discuss the possible association between glymphatic outflow and extent of TSS in patients with IIH. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209529
Effect of Ubrogepant on Patient-Reported Outcomes When Administered During the Migraine Prodrome
Dr. Tesha Monteith discusses the Neurology article, "Effect of Ubrogepant on Patient-Reported Outcomes When Administered During the Migraine Prodrome: Results From the Randomized PRODROME Trial" by Richard B. Lipton and colleagues, available in the September 24th issue of Neurology or at neurology.org. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209745
Large Study Finds COVID Vaccination Does Not Increase Multiple Sclerosis Relapses
Dr. Rae Bacharach discusses the Neurology Today article, "Large Study Finds COVID Vaccination Does Not Increase Multiple Sclerosis Relapses" by Susan FitzGerald, available in the September 5th issue of Neurology Today or at neurologytoday.com. Show reference: https://journals.lww.com/neurotodayonline/fulltext/2024/09050/large_study_finds_covid_vaccination_does_not.3.aspx
Spinal Muscular Atrophy Update in Best Practices - Part 3
In the third episode of this three-part series, Dr. Stacey Clardy and Dr. Mary Schroth discuss the critical objective of advancing the quality of life for individuals with SMA in the coming years. Show reference: https://www.neurology.org/doi/full/10.1212/CPJ.0000000000200310
Specialist Physiotherapy for Functional Motor Disorder
Dr. David Perez and Dr. Glenn Nielsen discuss the effectiveness of physiotherapy in treating functional motor disorder and to determine the best approach for physiotherapy treatment. Show reference: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00135-2/fulltext
Spinal Muscular Atrophy Update in Best Practices - Part 2
In the second episode of this three-part series, Dr. Stacey Clardy and Dr. Mary Schroth discuss the currently available treatments for spinal muscular atrophy. Show reference: https://www.neurology.org/doi/full/10.1212/CPJ.0000000000200310
Spinal Muscular Atrophy Update in Best Practice - Part 1
In the first episode of this three-part series, Dr. Stacey Clardy and Dr. Mary Schroth discuss the most common types of spinal muscular atrophy. Show reference: https://www.neurology.org/doi/full/10.1212/CPJ.0000000000200310
Blood Biomarkers to Detect Alzheimer Disease - Part 2
In part two of this series, Dr. Gregg Day and Dr. Sebastian Palmqvist discuss how this new blood test can enhance the accuracy of diagnosing Alzheimer's disease in patients with cognitive symptoms. Show reference: https://jamanetwork.com/journals/jama/fullarticle/2821669
Outcomes of Patients With MCI With Lewy Bodies or Alzheimer Disease - Part 2
In the second part of this two-part series, Dr. Jeff Ratliff and Dr. Calum Hamilton discuss the clinical criteria that listeners should look out for, indicating a subtype of mild cognitive impairment known as DLB, which could potentially progress into a full dementia with Lewy body phenotype. Show reference: https://www.neurology.org/doi/10.1212/WNL.0000000000209499
Blood Biomarkers to Detect Alzheimer Disease - Part 1
In part one of this two-part series, Dr. Gregg Day and Dr. Sebastian Palmqvist discuss the top-line findings from the study exploring the diagnostic performance of blood biomarkers for Alzheimer disease in clinical cohorts. Show reference: https://jamanetwork.com/journals/jama/fullarticle/2821669