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Naked Genetics, from the Naked Scientists

Naked Genetics, from the Naked Scientists

109 episodes — Page 2 of 3

Ep 59Genes, laws and Brexit

We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when the UK leaves the EU? Plus, our gene of the month comes with a tale behind it. Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 201729 min

Ep 58All human life is here

The story of human evolution is long and complicated, but the simple truth is - you're only here because your ancestors got lucky. Plus, we wind the clock back to the very start of human life, and discover how new research is pushing back the frontiers of human embryology. Plus a suitably festive gene of the month. This is the Naked Genetics podcast for December 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists

Dec 14, 201629 min

Ep 57Searching for switches

This month we're delving into the junk in the genome - or, to put it more correctly - our non-coding DNA. Less than 2 per cent of the human genome contains protein-coding genes, so what does all the rest do? Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 201630 min

Ep 56Testing, testing

We hear more than ever about the secrets hidden in our genes, from our risk of diseases to traits such as intelligence or even sporting ability. But can we really test for them? And just because we can, does that mean we should? Plus, an extremely popular - and extremely distracting - gene of the month. This is the Naked Genetics podcast for October 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists

Oct 13, 201630 min

Ep 55Hello Dolly

This month we've got a special bonus-length podcast commemorating twenty years since the birth of Dolly the Sheep, the first mammal cloned from an adult cell. Her birth changed the scientific world, and led to the development of other transformative technologies. Plus, our gene of the month is keeping a straight face. Like this podcast? Please help us by supporting the Naked Scientists

Sep 13, 201641 min

Ep 5440 years of selfishness

40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on how it changed the way many people think about genetics. Plus, linking nurture to nature, and a gigantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Aug 13, 201630 min

Ep 53Signal to noise

Building a baby is a complicated business, with millions of cells needing to work together. So how does it happen? Plus, how big data is making big strides in big genes, and our gene of the month is going round and round in circles. Like this podcast? Please help us by supporting the Naked Scientists

Jul 13, 201630 min

Ep 52Genes for all

Genes, genomes and genetic technology are playing increasingly important parts in our lives, industries, food and healthcare, and at a point in the not-too-distant future we're probably going to have to grapple with at least some of the contents of our DNA. But is the public really prepared to look inside its genes? Plus, the company aiming to bring molecular biology labs for all, and our gene of the month is crunchy on the outside. This is the Naked Genetics podcast for June 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists

Jun 13, 201630 min

Ep 51Check your compatibility

You may not realise it, but your health, immune system and even love-life are governed by the particular set of so-called compatibility genes that you inherit. There are thousands of different variations in these genes, but why do we have such diversity and does it matter? Plus, we dig into the latest research on cancer genetics - how studying hundreds of tumour genomes might bring forward new breast cancer cures. Like this podcast? Please help us by supporting the Naked Scientists

May 13, 201630 min

Ep 50What's in your genes?

As the costs of DNA analysis come down, we've seen the rise of direct-to-consumer genetic testing, allowing anyone to spit in a tube, pop it in the post and get a personalised readout direct to their inbox. But what do these tests actually reveal? Plus, how advertising execs can help us talk about genes, digging up the secrets in dogs genomes, and our gene of the month is totally legless. Like this podcast? Please help us by supporting the Naked Scientists

Apr 13, 201630 min

Ep 49Designer genes

The recent invention of powerful precision tools for editing the human genome - known as CRISPR, has opened up new worlds of possibilities for researchers seeking to understand how our genes work - and also those who want to permanently change the human genome for generations to come. But are we on the road to designer babies? Plus, we unpack the latest cancer breakthrough, and our gene of the month is making a terrible racket. Like this podcast? Please help us by supporting the Naked Scientists

Mar 14, 201632 min

Ep 48Crazy for CRISPR

It's the hottest new biotechnology technique to hit the headlines since well, since ever. CRISPR is a precision set of genome editing tools enabling scientists to cut and paste together DNA in any organism, exactly how they want - and the implications for human health, and even humanity, are huge. Plus, linking genetics to lifestyle, and our gene of the month is black and white and very cute. Like this podcast? Please help us by supporting the Naked Scientists

Feb 14, 201630 min

Ep 47Naked Genetics 47

This month we bring you a bumper edition, packed full of all our favourite bits from the past four years. Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 201657 min

Ep 46Naked Genetics 46

Synthetic biology - engineering life - is set to revolutionise the world, but how? We'll be hearing about some of the most exciting applications for synthetic biology, and how it's being commercialised. Plus, our gene of the month has got itself all in a twist. Like this podcast? Please help us by supporting the Naked Scientists

Dec 14, 201530 min

Ep 45Why don't elephants get cancer?

Animals like elephants and whales are made up of many more cells than a human, or a mouse, and they live far longer. Yet they hardly ever get cancer - and the big question is why? Plus, revolutions in genetics, and a magical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 201530 min

Ep 44Engineering life

Imagine designing bacteria that can do whatever you want - from cleaning up oil spills to churning out the latest cancer treatments - ordering the biological parts online and building it in a couple of weeks. This is no longer the stuff of dreams, but the reality of synthetic biology. Plus, tracing European genes, how parasites manipulate our immune systems, I take part in a research project to find out if sociability is in my genes, and our gene of the month is looking for wedded bliss. Like this podcast? Please help us by supporting the Naked Scientists

Oct 13, 201530 min

Ep 43Hundreds and Thousands

When it comes to figuring out which genes and genetic variations are linked to particular traits and diseases, there's only one way to do it, and that's to go large, with cohort studies involving hundreds or even thousands of volunteers. We meet the Born In Bradford bunch, a Canadian cohort, and more than a few pairs of twins. Plus, oh my God, they killed our gene of the month! Like this podcast? Please help us by supporting the Naked Scientists

Sep 13, 201530 min

Ep 42Mysterious methylation

There's more to life than the four letters of DNA, and our cells use a chemical tag known as DNA methylation to mark out certain parts of the genome, helping cells to remember what they're doing. And, as you might expect, it's pretty important. Plus, how your GCSE success could be encoded in your genes, an important molecular cause of autism identified, and an illuminating gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Aug 13, 201530 min

Ep 41The wonderful world of epigenetics

Genes are the instructions that tell our cells what to do, but how do different types of cells know which genes to switch on or off at the right time? The solution lies in epigenetics - the molecular bells and whistles that act on top of our DNA to control gene activity. Plus, a new gene involved in severe obesity, and a mythical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jul 13, 201530 min

Ep 40Breeding a better cow

For centuries, breeders have been selecting plants and animals with desirable genetic traits. So how have some of these changes come about, and where will new genetic technologies take our food in the future? Like this podcast? Please help us by supporting the Naked Scientists

Jun 13, 201530 min

Ep 39The story of maize

You may not realise it, but all the food you eat has been genetically altered over time by plant and animal breeders, capturing advantageous traits to grow more nutritious and easy-to-farm foods as efficiently and healthily as possible. Maize, or corn as it's often know, is a prime example of this change. Plus, is attractiveness to mosquitoes in your genes? And our gene of the month is small but significant. Like this podcast? Please help us by supporting the Naked Scientists

May 13, 201530 min

Ep 38Patenting and preserving genes

There are few things in life as important as the food we eat, but making sure that we guard the genes in our crops for the future is just as important. Plus, we take a look at some of the intellectual property issues surrounding our food, learn squid's surprising secret, and our gene of the month might be a mayor. Like this podcast? Please help us by supporting the Naked Scientists

Apr 13, 201530 min

Ep 37A hundred thousand genomes

Over the past year the Government has unveiled an audacious programme under the banner of Genomics England, aiming to sequence the genomes of 100,000 people affected by cancer and rare genetic diseases. We take a look at some of the practical and ethical issues around the project. Plus, our gene of the month comes from the land of the forever young. Like this podcast? Please help us by supporting the Naked Scientists

Mar 14, 201530 min

Ep 36Genetically Modified plants

Genetically modified, or GM, crops are a hot topic. Some people are deeply suspicious of the technology while others see it as an effective and efficient way of generating bountiful, healthier harvests. Plus, purple tomatoes, a giant of a gene involved in heart disease, and what's in a name? We take a look at the naming of genes. Like this podcast? Please help us by supporting the Naked Scientists

Feb 14, 201530 min

Ep 35Clever mice and drunken flies

How do we learn complex tasks like playing the piano? Why can we remember things better after a good night's sleep? And why do people - and fruit flies - drink again after the hangover from hell? The answers are all in your genes. Plus, why large-scale searches for so-called "genes for schizophrenia" and other psychiatric diseases are turning out to be trickier than we thought, and a gene of the month with a touch of Scottish - or maybe Hollywood - spirit. Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 201530 min

Ep 34Searching for the engram

For many years scientists have been searching for the mysterious engram - the place in the brain where memories are kept. And thanks to advances in genetics and neurobiology, it looks like they're now getting close to finding it. Plus, contagious cancers in dogs and devils, and our gene of the month prefers the cold. Like this podcast? Please help us by supporting the Naked Scientists

Dec 14, 201430 min

Ep 33Targeting cancer genes

Every year in the UK more than 330,000 people are diagnosed with cancer. The good news is that more and more are surviving, and there's hope that the new generation of genetic research and targeted therapies will bring more cures in the future. But is cancer a cleverer enemy than we thought? Plus sealion genital cancers, and an over-excited gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 201430 min

Ep 32Genes, ageing and metabolism

Could we one day be popping pills that tweak our metabolism and make us live longer? It's not as far off as you might think. Plus, the cow genome goes large, bat flu flies into focus, and an untidy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Oct 13, 201430 min

Ep 31Long live our genes

Every day we get older, and whether you're desperately resisting the march of time, or embracing the ageing process, most of us would agree we want to live as long, healthy lives as possible. We'll be finding out how genetics research can help. Plus, making fingers with Alan Turing, growing lizard tails, and a long-lived gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Sep 13, 201430 min

Ep 30Genes for sore eyes

From the beauty of a sunset or the ugliness of war to the smile on a loved one's face, our eyes bring us all kinds of information about the world around us. now researchers are working to develop new therapies for people who have lost this precious sense. Plus, smelling elephants, marmoset twins, and an all-seeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Aug 13, 201430 min

Ep 29Issues for genetic testing

Whether we like it or not, we're heading further along the road of genetic testing, not just for single genes but for complex diseases and even ancestry. But can the results of gene tests change our behaviour? Plus colouring crows, electric eels, gluing chromosomes and a sketchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jul 13, 201430 min

Ep 28Gene therapy - Cystic fibrosis, blindness and more

Twenty years ago, gene therapy was a great hope for the future of medicine - directly tinkering with faulty genes to cure diseases, but progress has been slow. Now, things seem to be changing. Plus, silencing crickets, evolving brain and brawn, and a flowery gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jun 13, 201430 min

Ep 27Nature, nurture and wiring the brain

The more we understand about the genetic variations that affect our brains, the more questions are raised - for example, are we a product of nature or nurture, and what should we test for? Plus, why Y loss is bad for men, the usefulness of junk DNA, and a crunchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

May 13, 201430 min

Ep 26Genes, depression and schizophrenia

Around one in four adults in the UK experiences mental health problems in any year, and mental illness is a major problem for sufferers, their loved ones, and society. It's becoming clear that genes are involved, but what do we actually know? Plus, artificial chromosomes, autism in the womb, and a toddling little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Apr 13, 201430 min

Ep 25DNA damage and repair

Every second your DNA is under assault - not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We'll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Mar 14, 201430 min

Ep 24Smells like gene spirit

Smell is probably the oldest sense, hardwired right into our brains and closely linked to memory. Now researchers are trying to unravel the complex genetics that underpin it. Plus, contagious dog genital cancers, gene therapy for blindness, and a rather slimy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Feb 14, 201430 min

Ep 23Now hear this

Hearing loss is distressing, whether it occurs later in life or in childhood. Now researchers are starting to unpick the genetic causes behind some of these problems. Plus, mice on drugs, stress and death, and a wobbly gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 201430 min

Ep 22Taking shape

Across the natural world, cells organise themselves into a wonderful array of shapes and structures. But how do they do this? Plus, building bones, plant sex in space, and a rather plump gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Dec 14, 201330 min

Ep 21Come together

All living cells are made up of protein molecules - but how do they organise themselves into structures? Plus bee sex, tough mice, and a happily married gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 201330 min

Ep 20Have a heart

The heart is a vital biological pump, beating around a billion times in a lifetime. But faulty genes can cause big problems. Plus, taming the tiger genome, solving citrus sickness, and our gene of the month is for all you hopeless romantics out there. Like this podcast? Please help us by supporting the Naked Scientists

Oct 13, 201330 min

Ep 19Genes and genealogy

Who do you think you are? And is the answer in your genes? This month we're delving into genes and genealogy. Plus, putting an end to genetic determinism, and an ancient Egyptian gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Sep 13, 201330 min

Ep 18Genes, infections and immunity

Why can some people stay fit as a fiddle, while other seem to catch every bug that's going? As you might expect, the answer lies in our genes. Plus, a multitude of mutant mice, the state of gene therapy for epilepsy, and an unseeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Aug 13, 201330 min

Ep 17Let's talk about sex

Summer loving is in the air, so what better time to think about sex? But we're not going to get graphic - we're talking about the genetics of sex determination. Plus, why turkeys need a wingman, figuring out fingerprints, and a leggy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jul 13, 201330 min

Ep 16The future of fingerprinting

Our genes are our unique calling card, and DNA analysis has been used to solve crimes and resolve paternity disputes for decades. Now new genetic technology promises to revolutionise medicine. Plus, we meet the man who invented genetic fingerprinting, discuss Angelina Jolie's breasts, and savour a cheesy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Jun 13, 201330 min

Ep 15Genomics - Hope or hype?

Genetic technology is expanding at a pace that few can keep up with, with huge amounts of data being generated every week. But is this explosion of information delivering meaningful advances for patients? Plus, how one scientist tracked down the gene fault behind his own disease, what sequencing the HeLa genome means for genetic privacy, and a Pythonesque gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

May 13, 201330 min

Ep 14Doing the twist - packing DNA

Almost every single cell of your body is packed with more than two metres of DNA, containing your genes. But not only does it have to be packed up to fit in there, it also has to be organised and read. Plus, how genetic variations are linked to cancer risk,analysing dinosaur DNA, and an adventurous gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Apr 13, 201330 min

Ep 13Beautiful otherness - autism genetics

It's thought that around one in a hundred children in the UK is somewhere on the autistic spectrum - a complex range of disorders that can be challenging to understand and live with. But recent advances in genetics are bringing hope for new therapies that might help. Plus, we look at the genes underlying Specific Language Impairment, find out why cancer has the X factor, and meet a hopeless-sounding gene of the month. Like this podcast? Please help us by supporting the Naked Scientists

Mar 14, 201330 min

Ep 12The wonderful world of RNA

You've probably heard of DNA, but what do you know about RNA? As well as being the molecule that shuttles information from our genes into our cells, it also plays a huge number of other roles in all cells, from bacteria and viruses to tiny worms, plants and humans. Plus we delve into quadruplex DNA, wonder about the wolf genome, speculate on skin colour and our gene of the month has a literary twist. Like this podcast? Please help us by supporting the Naked Scientists

Feb 14, 201330 min

Ep 11Fitting into your genes - the genetics of obesity

The gym is full, the pubs are empty - it can only be January, as a good proportion of the population resolves to shape up and lose weight. But are your efforts going to help you fit into your jeans (with a J), or are you just fighting against your genes (with a G)? Plus, we discuss how genes might jump between cows and snakes, and we've got gout, goats, giant pandas and a glass bottom boat.This is the Naked Genetics podcast for January 2013 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 201330 min

Ep 10Cancer genetics - When good cells go bad

Cancer is literally the enemy within us -it starts when our own cells get damaged and go rogue, multiplying out of control and spreading around body. But how can we use new genetic knowledge to beat it? Plus, decoding the wheat genome, finding out where birds came from, and our gene of the month is more art than science. Like this podcast? Please help us by supporting the Naked Scientists

Dec 14, 201230 min