
Season 2 · Episode 323
Is Your Gut Telling Your Brain What to Think?
Discover why your gut is a "second brain" and how trillions of microbes influence everything from your mood to your metabolism.
My Weird Prompts · Daniel Rosehill
January 27, 202625m 30s
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Show Notes
In this deep dive, Herman and Corn explore the fascinating world of the human microbiome, an ecosystem of trillions of microbes that functions as a "forgotten organ" weighing as much as the liver. They discuss how this "metabolic engine" dictates our immune response, hormone production, and even our mental health through the complex gut-brain axis. From the long-term impacts of gallbladder surgery on bile acid signaling to the "scorched earth" effect of antibiotics, this episode reveals why we are less like individuals and more like "holobionts"—synergistic communities where microbes might be making 80% of the decisions. Learn about the future of precision biotics and why your next mood swing might actually be a signal from your gut bacteria.