Metabolic Mind

There’s been a lot of buzz—and confusion—about the new Keto-CTA study, examining plaque progression in Lean Mass Hyper-Responders (LMHRs).Much of the social media debate has centered on whether high LDL on keto is safe or dangerous, driven largely by how to interpret the supplemental table comparing this study to others on LDL and plaque progression.In this episode of the Metabolic Mind Podcast, we sit down with Dr. Matthew Budoff, a world-renowned cardiologist, cardiac CT researcher, and the study's lead investigator, to discuss the the supplemental table, what the plaque markers mean, and how this fits into the discussion of high- vs -low-risk plaque progression.In this episode, we cover:✅ What PAV (Percent Atheroma Volume) is, what it actually measures, and why it matters✅ Why a 50% increase in plaque may sound scary, but can be deceiving✅ The difference between “treatment-naive” and “treated” participants✅ What the Miami Heart Study comparison reveals about keto, LDL, and plaque✅ Why LDL alone may not tell the whole story about heart disease risk✅ How some high-risk individuals may still benefit from statins and other therapiesThis study doesn’t answer whether keto causes heart disease or not. Instead, it shows that high LDL on a ketogenic diet is not a reliable predictor of plaque progression across all individuals. What is predictive? The presence of existing plaque.💡 Key takeaway: Relying on surrogate markers of heart disease, like LDL and ApoB, is not the best way to assess heart disease risk in all populations.If you're concerned about how elevated LDL may be affecting your heart health, the best next step is to speak with your doctor about cardiac imaging to directly assess plaque and gain a clearer picture of your individual risk.Expert Featured:Dr. Matthew BudoffX: https://x.com/budoffmd?lang=enhttps://lundquist.org/matthew-budoff-mdResources Mentioned:Plaque Begets Plaque, ApoB Does Nothttps://www.jacc.org/doi/10.1016/j.jacadv.2025.101686CMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is LDL cholesterol the best way to measure and predict heart disease?New research suggests no!Dave Feldman is an engineer turned citizen scientist who has devoted his life to understanding a phenomenon that some individuals around the world are experiencing: a robust increase in LDL cholesterol while on a ketogenic diet.Dave’s past research has identified a unique phenotype dubbed Lean Mass Hyper-Responders (LMHRs). LMHRs respond to ketogenic therapy with a metabolic profile that includes elevated LDL-C and ApoB levels with otherwise healthy metabolic markers, including low triglycerides, high HDL, low blood pressure, low insulin resistance, and low BMI.In Dave’s most recent publication, what most doctors would consider dangerously high LDL levels in LMHRs did not correlate with an increased risk of heart disease.In this video, Dr. Bret Scher sits down with Dave Feldman to discuss this groundbreaking study and its implications for ketogenic therapy and cardiology.Key Takeaways:LMHRs on a long-term ketogenic diet who show elevated LDL can show robust metabolic healthLDL-C and ApoB were not linked to plaque progression in LMHRsExisting plaque did predict future plaque accumulation in LMHRsIndividualized approaches to cardiovascular risk assessment are crucial to serve this group better.🎬 These exciting new findings are featured in Dave Feldman and Jen Isenhart’s upcoming documentary, The Cholesterol Code, the story of how one engineer’s health experiment sparks a global investigation, exposing myths about cholesterol and reshaping our understanding of heart health. Real stories of healing from disease with ketogenic diets provide a blueprint for using food as powerful medicine.Visit cholesterolcodemovie.com to learn more about the film and to be the first to hear about private screenings and the general release in the fall.Expert Featured:Dave FeldmanCEO, Citizen Science Foundationhttps://x.com/realDaveFeldmanCholesterol Code website: https://cholesterolcode.com/Resources Mentioned:Coronary Artery Plaque Progression in Asymptomatic Lean Mass Hyper-Responders: A Case Serieshttps://www.jacc.org/doi/10.1016/j.jacadv.2025.101686CMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can type 2 diabetes be reversed, eliminating the need for medications with completely normal blood sugar levels?For decades, type 2 diabetes has been considered a chronic, progressive conditions and the standard approach has been to just manage it to slow it down. But what if remission was possible?Dr. David Unwin, a UK-based NHS physician, has demonstrated how low-carb and ketogenic interventions can lead to drug-free diabetes remission. His work has transformed patient outcomes and challenged conventional medical guidelines.In this interview, Dr. Unwin shares how he has helped over 150 patients achieve drug-free remission using a low-carb ketogenic approach. We also cover:🔹 The science behind reversing type 2 diabetes🔹 How his NHS clinic has achieved one of the highest diabetes remission rates in the world🔹 The role of real-world data in changing medical practice🔹 The resistance from traditional healthcare and how to overcome it🔹 Why media coverage and patient success stories are crucial for spreading awareness🔹 Practical tips for patients and doctors interested in metabolic healthDr. Unwin's research-backed approach challenges conventional wisdom and offers a hopeful alternative for those struggling with metabolic conditions.Join Dr. Bret Scher as he and Dr. Unwin dive into the science, data, and real-world applications of ketogenic therapy not just for diabetes, but for metabolic and mental health as well.#MetabolicHealth #KetogenicTherapy #DiabetesRemissionExpert Featured:Dr. David UnwinX: https://x.com/lowcarbgp?lang=enResources MentionedWhat predicts drug-free type 2 diabetes remission? Insights from an eight-year general practice cohort studyRenal function in patients following a low carbohydrate diet for type 2 diabetes: a review of the literature and analysis of routine clinical data from a primary care service over 7 yearsDr. Tro Kalayjian Publishes Research Paper Confirming the Benefits of Lifesyle-Based Metabolic CareTOWARD HealthDr. Unwin’s Low Carb Diet SheetCMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Not all medical research is created equal, so how do we know which studies to trust?The phrase evidence-based medicine (EBM) is often misunderstood and misused. What does it truly mean to rely on evidence in clinical decision-making?Dr. Gordon Guyatt, the father of the term evidence-based medicine, explains how to assess scientific studies, understand the strength of different types of evidence, and apply findings to clinical decisions.Want to make better-informed health decisions? This interview will help you learn how to critically assess medical evidence for yourself. In this conversation, Dr. Guyatt breaks down:✅ Why some studies are more trustworthy than others✅ The limitations of observational studies in nutrition and medicine✅ How the GRADE framework categorizes evidence from high to low certainty✅ How to critically assess nutrition and mental health research✅ The importance of patient values in clinical decision-makingAs new chronic disease treatments emerge from rapidly evolving research, understanding the quality of evidence is more important than ever. The ability to distinguish robust data from weak correlations isn’t just a skill—it’s essential for making informed, effective decisions in patient care.#MetabolicMind #EvidenceBasedMedicine #MedicalResearch #NutritionScience #GRADEMethod #HealthDecisionsExpert Featured:Dr. Gordon Guyatt, MDResources Mentioned:Core GRADE WorkshopCMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Can the ketogenic diet help kids with bipolar disorder? We are excited to announce new research is finally exploring this question.The ketogenic diet was first discovered over 100 years ago for children with epilepsy. Could ketogenic therapy also improve mental health outcomes for youth with serious conditions like bipolar disorder? Dr. Kirk Nylen joins Dr. Bret Scher to discuss two groundbreaking studies underway that are tackling this question head-on.In this episode, they dive into:🔬 The Child and Adolescent Bipolar Network (CABIN) study – a multi-site RCT testing ketogenic therapy in pediatric bipolar disorder🏥 Children’s Mental Health Resource Center (CMHRC) study – A real-world pilot study exploring the practical application of ketogenic interventions for kids with bipolar🛠️ How data emerging from these studies could add new tools to clinicians' toolboxesAs the youth mental health epidemic continues to rise, we must continue to pursue better solutions. We are hopeful that this research will not only expand treatment options but also inspire more pediatric clinicians to consider the powerful role ketogenic therapy can play in improving mental health outcomes for children.Expert Featured:Dr. Kirk Nylen, PhDManaging Director of Neuroscience as Baszucki GroupResources MentionedChildren’s Mental Health Resource Centerhttps://cmhrc.orgCMEs MentionedManaging Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.Timestamps:0:00 - Introduction to ketogenic interventions for pediatrics and Kirk Nylen, PhD.2:17 - The history of ketogenic therapies in pediatrics. How safe are ketogenic therapies for children?6:37 - Bipolar study on children: background of the Child Bipolar Network study. How are they testing and what are they looking for?10:11 - How does the Children’s Mental Health Resource Center address the gaps in pediatric bipolar research?13:25 - Summary of the state of research on ketogenic therapies for bipolar in children and what questions remain.

Can you safely taper off psychiatric medications? And what are the potential harms of long-term psychiatric care?Laura Delano spent years as a professional patient, navigating psychiatric diagnoses, multiple medications, and a life defined by treatment.In this interview, Laura discusses her 13-year experience as a psychiatric patient, the impact of long-term medication use, and how she took control of her health to successfully taper off multiple psychiatric drugs.Now, as the founder of Inner Compass Initiative and author of Unshrunk: A Story of Psychiatric Treatment Resistance (available March 18, 2025), she’s dedicated to helping others navigate informed choices about psychiatric medications, diagnoses, and withdrawal.💡 In this episode, we cover:✅ Laura’s personal story of polypharmacy and its effects✅ The impact of long-term psychiatric medication✅ The challenges of tapering and withdrawal✅ How Laura has rebuilt her life beyond medications✅ How Laura built a nonprofit to support others on the same path✅ The role of diet, lifestyle, and community in mental health recovery✅ Why informed consent is crucial for psychiatric treatment decisions✅ The mission of Inner Compass InitiativeLaura’s new book Unshrunk: A Story of Psychiatric Treatment Resistance is available March 18, 2025.⚠️ Trigger Warning: This conversation includes discussion of suicidality and a suicide attempt. Please take care when watching.#MentalHealth #Psychiatry #Deprescribing #PsychiatricMedication #Tapering #MetabolicPsychiatryExpert Featured:Laura DelanoResources Mentioned:Inner Compass Initiativehttps://www.theinnercompass.org/Laura’a New Book: Unshrunk: A Story of Psychiatric Treatment Resistancehttps://www.amazon.com/Unshrunk-Story-Psychiatric-Treatment-Resistance/dp/1984880489The Challenges of Going off Psychiatric Drugshttps://www.newyorker.com/magazine/2019/04/08/the-challenge-of-going-off-psychiatric-drugsCMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Brain Energy and metabolism appear to play critical roles in the development and treatment of psychiatric disorders like bipolar disorder, depression, and schizophrenia. And emerging research suggests that our gene expression influences how our brain uses energy, thus linking the fields of genetics and metabolism.In this episode, Dr. Harry Pantazopoulos, Associate Professor in the Department of Psychiatry and Human Behavior at the University of Mississippi Medical Center, joins Dr. Bret Scher to discuss fascinating new research into the relationship between gene expression and metabolism in serious mental illness.Dr. Pantazopoulos’ study reveals a fascinating insight: while metabolic dysfunction is a common feature of serious mental illnesses, each condition exhibits its own distinct patterns of altered gene expression that impacts metabolic function. This suggests that the underlying metabolic dysfunction in mental illness arises through different mechanisms unique to each disorder.In this interview you will learn: The benefits of studying metabolic function and gene expression of the amygdala Which genes show altered expression in each mental illness, and how these changes affect metabolism How shifting the brain’s energy source from glucose to ketones could offer a promising way to address changes in metabolic gene expression How these study findings could translate to targeted clinical careAlthough these findings are not yet ready to directly influence clinical psychiatric care models, they provide a critical foundation for future research aimed at tailoring metabolic therapies to the unique needs of each individual.Expert Featured:Harry Pantazopoulos, MDLinkedIn: https://www.linkedin.com/in/harry-pantazopoulos-04460413/X: @HarryPantazopo1Studies Mentioned:Transcriptomic Analysis of the Amygdala in Subjects with Schizophrenia, Bipolar Disorder and Major Depressive Disorder Reveals Differentially Altered Metabolic PathwaysDifferentially Altered Metabolic Pathways in the Amygdala of Subjects with Schizophrenia, Bipolar Disorder and Major Depressive DisorderCMEs Mentioned:Managing Major Mental Illness with Dietary Change: The New Science of HopeBrain Energy: The Metabolic Theory of Mental IllnessFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is psychiatry stuck in the 19th century? For decades, psychiatry has relied on trial and error but is there a better way to provide precise, personalized, and preventative treatment?Dr. Alexander Niculescu, professor of psychiatry at the University of Arizona and CEO of MindX Sciences, is at the cutting edge of transforming psychiatry into an objective, data-driven field. With blood tests evaluating specific biomarkers, doctors may now be able to measure mental health, better understand symptoms, and predict which treatments will work best.In this conversation, Dr. Niculescu explains how his research is helping reshape how we diagnose and treat mental illness allowing for a more personalized approach and potentially better outcomes. He shares research demonstrating how utilizing biomarkers can allow practitioners to better understand the current state of a patient’s mental health to assist in prevention and tailor both medications and lifestyle interventions for better outcomes.In this episode, you’ll learn:Why psychiatry is still practiced like 19th-century medicine and how to modernize itHow blood tests can pinpoint the right treatment for a patient including lifestyle interventions, medication choice, and dosingHow blood tests can identify the nuanced difference between mental illnesses like depression and bipolar disorder at a biological levelWhy these tests could be more reliable than genetic testingHow early screening could help prevent serious mental illnessThe future of personalized lifestyle recommendations for mental healthAt Metabolic Mind, we believe mental health care must evolve to incorporate metabolic interventions alongside innovative diagnostic tools. Our vision is a future where the metabolic health of every individual is assessed and addressed with evidence-based interventions, leading to improved mental health for all.Expert Featured:Dr. Alexander Niculescuhttps://mindxsciences.com/https://www.linkedin.com/in/alexander-niculescu-md-phd-b460a75/Studies Mentioned:Special Report: Precise, Personalized, and Preventive Psychiatryhttps://doi.org/10.1176/appi.pn.2024.12.12.27CMEs MentionedManaging Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is it possible for ketogenic therapy to significantly reduce schizoaffective symptoms in 2 weeks? What about putting symptoms into complete remission in 6 weeks?Licensed Mental Health Counselor Nicole Laurent joins Dr. Bret Scher to discuss her newly published case series showcasing the dramatic improvements in individuals with schizoaffective disorder using ketogenic metabolic therapy.In this interview, Nicole shares:The life-changing stories from the patients and their familiesHow she collaborated with healthcare teams to ensure better outcomesHow she determines the right type of ketogenic diet for each patientThe role of nutrient deficiencies and supplementation in treatmentHow medications were handled and her perspective on medication changes with ketogenic therapyThe profound transformations in her patients’ lives, including returning to school and regaining independenceThese stories offer hope and add to the growing evidence that ketogenic therapy can help individuals struggling with mental illness.Want to hear more real-life experiences of people reclaiming their mental health through metabolic therapy? Hear from our community of experts by experience, including their challenges, setbacks, and successes on the path to recovery at metabolicmind.org/think-smart.Expert Featured:Nicole Laurent, LMHChttps://mentalhealthketo.com/Founder and Medical Director of Mental Health KetoX: @KetoCounselorLinkedIn: https://www.linkedin.com/in/nlaurent/Instagram: mentalhealthketo/Studies MentionedKetogenic metabolic therapy for schizoaffective disorder: a retrospective case series of psychotic symptom remission and mood recoveryhttps://doi.org/10.3389/fnut.2025.1506304CMEs MentionedManaging Major Mental Illness with Dietary Change: The New Science of Hopehttps://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616Brain Energy: The Metabolic Theory of Mental Illnesshttps://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Dr. Iain Campbell, a researcher at the University of Edinburgh, discusses his groundbreaking pilot study on ketogenic therapy for bipolar disorder with Dr. Bret Scher. Having personally experienced the benefits of ketosis for his own bipolar type II depression, Dr. Campbell delves into the link between metabolic health and mental well-being.Dr. Campbell shares how his recent study reveals a correlation between higher ketone levels and improvements in mood, energy, impulsivity, and anxiety in patients with bipolar disorder. He also highlights the intriguing brain imaging results that indicate reductions in brain glutamate, hinting at one of the potential mechanisms behind ketogenic therapy's effectiveness.Key Topics Covered:The correlation between ketone levels and mood stabilizationDr. Campbell’s personal journey using ketogenic therapy for bipolar disorderHow ketosis impacts brain glutamate levelsThe role of metabolic psychiatry in treating mental illnessThe future of metabolic treatments at the newly established UK Metabolic Psychiatry HubDr. Campbell's pioneering work at the Metabolic Psychiatry Hub is advancing the field of metabolic psychiatry by integrating research and treatment, demonstrating how ketogenic therapy can be a powerful tool for addressing both metabolic and mental health in the treatment of bipolar disorder.New Study:A Pilot Study of a Ketogenic Diet in Bipolar Disorder: Clinical, Metabolic and Magnetic Resonance Spectroscopy Findingshttps://doi.org/10.1192/bjo.2024.841Experts Featured:Dr. Iain CampbellX: @IainCampbellPhDwww.metabolicpsychiatryhub.comFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Do psychiatric medications alter brain energy and metabolic health?Dr. Stephen Cunnane, a professor and researcher at the University of Sherbrooke, has been at the forefront of studying glucose and ketone metabolism in the aging brain, pioneering advanced imaging techniques to measure how the brain utilizes these critical energy sources with neurodegenerative conditions like Alzheimer’s and Parkinson’s.While glucose PET imaging has long been used to study brain energy metabolism, Dr. Cunnane’s team was the first to develop ketone PET imaging, allowing researchers to look at the relationship between glucose and ketone metabolism in the brain and understand how ketones support brain function when it struggles to use glucose for energy.Now, Dr. Cunnane has turned his attention to metabolic psychiatry and is working on a new study looking at brain energy metabolism in individuals experiencing first-episode psychosis. This study will allow researchers insights into the metabolic state of the brain at the onset of major mental illness and how psychiatric medications influence brain energy use.In this episode, you will learn:How the brain uses fuel as we age – Why glucose metabolism declines over time and how ketones may compensate in aging and neurodegenerative conditions.The first ketone PET imaging studies – How Dr. Cunnane’s team developed a method to directly measure ketone uptake in the brain and compare it to glucose metabolismPsychosis and brain energy metabolism – Examining glucose and ketone utilization in first-episode psychosis before and after antipsychotic treatment.Carbohydrate reduction in older adults – Findings from a study showing how moderate carb restriction improved metabolic and mental health in retirement home residents independent of weight loss.Parkinson’s disease and ketones – Investigating how exercise, exogenous ketones, and carbohydrate restriction may enhance brain energy supply and improve symptoms.Dr. Cunnane has been a pioneer in the field of ketogenic therapy and brain energy. In addition to all the incredible work he is doing in the aging brain, we are excited to see his new research focusing on such critical components of metabolic psychiatry.Expert Featured:Dr. Stephen Cunnanehttps://recherche-cerveau-sherbrooke.ca/en/laboratory-team/Studies MentionedA reduced carbohydrate diet improves glycemic regulation in hyperglycemic older people in a retirement home: the SAGE studyhttps://doi.org/10.1139/apnm-2024-0277Resources MentionedBrain Research Team Websitehttps://recherche-cerveau-sherbrooke.ca/en/Revolutionizing Assisted Living: Hal Cranmer's Ketogenic & Carnivore Approach to Senior Wellnesshttps://youtu.be/s86CFw0qhVc?feature=sharedFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources athttps://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How can we make sense of conflicting studies? One paper suggests a ketogenic diet reduces all-cause mortality, while another claims it raises blood pressure. Are large-scale survey tools like NHANES—the National Health and Nutrition Examination Survey—really the best way to answer these complex questions? In this insightful interview, Dr. Adrian Soto-Mota, an internal medicine clinician, educator, and data enthusiast, explains how to critically evaluate research findings. He highlights the strengths and limitations of different types of studies, using engaging analogies to help you better understand when and how to apply research conclusions. In this video you’ll learn: The importance of choosing the right tool (study) for the task Strengths and weaknesses of large population studies like NHANES Practical advice for interpreting conflicting health and nutrition research If you're passionate about understanding health research and making evidence-based decisions, this interview is a must-watch! Expert Featured: Dr. Adrian Soto-Mota X: @AdrianSotoMota Studies Mentioned Ketogenic diets are associated with an elevated risk of hypertension: Insights from a cross-sectional analysis of the NHANES 2007–2018 https://doi.org/10.1016/j.ijcrp.2024.200342 Comparing Very Low-Carbohydrate vs DASH Diets for Overweight or Obese Adults With Hypertension and Prediabetes or Type 2 Diabetes: A Randomized Trial https://doi.org/10.1370/afm.2968 The ketogenic diet has the potential to decrease all-cause mortality without a concomitant increase in cardiovascular-related mortality https://doi.org/10.1038/s41598-024-73384-x CMEs Mentioned Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more insights and education from Dr. Bret Scher, including interviews with leading experts in metabolic psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/. About us Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Pediatric and adolescent mental health challenges, including anxiety, depression, and ADHD, are reaching alarming levels and affecting millions worldwide. While the causes are still being explored, one potential contributing factor is the rising metabolic health epidemic, fueled by a harmful food environment. With current treatment options often coming with challenging side effects and failing to provide lasting relief, many families are turning to innovative, evidence-based solutions to support their children’s well-being and long-term development. In this interview, Dr. Lori Calabrese, a board-certified psychiatrist, shares her pioneering work in youth mental health care and discusses her experiences implementing ketogenic therapies in children and young adults. In this interview, you’ll learn: What’s the difference between ketogenic therapy for adults vs. children? How to introduce ketogenic therapy to children and young adults The importance of having families on board with ketogenic therapy How to help children and young adults adhere to ketogenic therapies Everyone deserves access to better mental health care, especially the young minds that hold the future to our society. Expert Featured: Dr. Lori Calabrese X: @loricalabresemd LoriCalabreseMD.com Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How Is a ketogenic diet different for women, and what impact does a ketogenic diet have on women’s hormones? The ketogenic diet sparks a lot of questions when it comes to women’s health—and for good reason. Social media and the internet are flooded with conflicting information. Fortunately, Dr. Madison Kackley, a research scientist at Ohio State University, brings evidence-based insights in this episode. As the leader of the SHE IS Laboratory, Dr. Kackley and her team are uncovering the unique ways ketogenic interventions can impact women’s health, considering crucial factors like hormonal fluctuations, menstrual cycles, and key life stages such as postpartum and perimenopause. In this episode, you’ll learn: Insights from the SHE IS Lab on ketogenic therapies for PCOS, postpartum depression, perimenopause, and more. How ketogenic therapies are helping restore menstrual cycles and improve hormonal health. The importance of personalized approaches and cycle tracking in women's health research. When ketone supplements may be beneficial for women’s health. How to adjust exercise and nutrition for different stages of the menstrual cycle. Join us as Dr. Kackley shares her passion for addressing the gaps in women-specific health studies and the promising future of metabolic-based interventions for women’s health. Expert Featured: Dr. Madison Kackley X: @KackleyMLPhD CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more insights and education from Dr. Bret Scher, including interviews with leading experts in metabolic psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/. About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Mental health care is at a critical crossroads. Millions of people are searching for effective treatments, yet conventional options often fall short, leaving many without significant or lasting relief. Compounding this issue is the lack of funding directed toward exploring novel, root-cause therapies. The urgency for change is clear. Dr. Chris Palmer, a Harvard psychiatrist and the author of Brain Energy, has been instrumental in raising awareness about the metabolic nature of mental illness. His pioneering work highlights how conditions like depression, bipolar disorder, and schizophrenia often stem from underlying metabolic dysfunctions, including glucose hypometabolism, neurotransmitter imbalances, inflammation, and oxidative stress. In this interview, Dr. Palmer dives into the science behind mental illnesses and shares groundbreaking insights into how ketogenic therapy is changing lives. In this interview, you’ll learn: Why the current mental health system struggles to provide effective care How ketogenic therapies and lifestyle changes are reshaping psychiatry The role of mitochondria and metabolism in brain health The urgent need for research on tapering medications safely The current state of mental health research funding and the path towards systemic change Why mental illness should be viewed as a systemic condition, not just a brain disorder This conversation highlights the urgent need for change in psychiatry, how metabolic therapies are offering new hope for those living with mental illness, and the path towards more effective evidence based care and better patient outcomes. Expert Featured: Dr. Chris Palmer X: @ChrisPalmerMD www.ChrisPalmerMD.com Purchase Brain Energy: https://brainenergy.com/#order-window Studies Mentioned Beyond comorbidities: metabolic dysfunction as a root cause of neuropsychiatric disorders https://www.cambridge.org/core/journals/bjpsych-advances/article/abs/beyond-comorbidities-metabolic-dysfunction-as-a-root-cause-of-neuropsychiatric-disorders/9B7489EF96DCA9F41005DD7E61B27023 The Ketogenic Diet as a Transdiagnostic Treatment for Neuropsychiatric Disorders: Mechanisms and Clinical Outcomes https://link.springer.com/article/10.1007/s40501-024-00339-4 CMEs Mentioned Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

What comes to mind when you think of assisted living? Likely not vibrant residents, nutritious meals, and improved physical and mental health—but Hal Cranmer is working to change that narrative. In this inspiring interview, Hal shares how his innovative approach to senior care integrates ketogenic and carnivore nutrition to boost activity, memory, and overall well-being in his facilities. Dive into the secrets of Hal’s success and learn how he’s transforming the lives of seniors by prioritizing health and vitality. If you’re passionate about holistic health or senior wellness, this is a story you won’t want to miss! Expert Featured: Hal Cranmer https://aparadiseforparents.com/ X: @HalCranmer Instagram: @assisted_living_hal_cranmer Follow our channel for more insights and education from Dr. Bret Scher, including interviews with leading experts in metabolic psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/. About us Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

How effective is exercise for treating depression, and how can we help more people use it as a cornerstone of treatment? The last decade we have seen mounting evidence that exercise can play a big role in mental health through a variety of mechanisms. In this interview, Dr. Nick Fabiano, a psychiatry resident and researcher, shares his innovative approach to using exercise as a therapeutic intervention, drawing from his recent co-authored paper. In this interview you’ll learn: Why exercise is comparable to antidepressants and therapy in treating mild to moderate depression. How a holistic, lifestyle-based approach can complement traditional treatments. The mechanisms linking exercise to improved mental health, including metabolic health benefits and social interaction. How to personalize exercise prescriptions for individuals based on their physical and mental health needs. Challenges of integrating exercise into psychiatric care Movement is a core pillar of our THINK + SMART program, embodying the 'M' in the acronym. Exercise not only has the remarkable ability to provide an immediate boost to mood and mental clarity but also fosters long-term adaptations that support both metabolic and mental health. As the field of metabolic psychiatry continues to grow, we are optimistic that exercise will become a foundational component in the standard of care for mental health treatment. Expert Featured: Nicholas Fabiano, MD X: @NTFabiano Studies Mentioned: How to Prescribe Physical Activity for Depression *https://doi.org/10.1024/2674-0052/a000099** Importance of Frequency, Intensity, Time and Type (FITT) in Physical Activity Assessment for Epidemiological Research https://doi.org/10.1007/BF03404889 The Effect of Exercise on Suicidal Ideation and Behaviors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://doi.org/10.1016/j.jad.2023.02.071 CMEs Mentioned Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more insights and education from Dr. Bret Scher, including interviews with leading experts in metabolic psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/. Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

The Dietary Guidelines for Americans (DGA) have the potential to shape the health of millions, but are they based on outdated or flawed evidence? In this powerful interview, Dr. Bret Scher and investigative journalist Nina Teicholz expose the controversial history of dietary policy, challenge the methodology of the DGA Advisory Committee, and discuss the urgent need for change to address rising rates of metabolic and mental health disorders. And they try to answer the burning question from the guidelines: Will eating more beans, peas, and lentils make all of us healthier? What you will learn in this interview: What is the importance of the Dietary Guidelines for Americans? How is the Dietary Guidelines Advisory Committee committee selected? How is the DGA created and what is the quality of evidence? What are the conflicts of interest in current and past DGA committees? How are decades-old biases shaping current dietary policies? How is the DGA failing to consider individual needs? What do we know about the upcoming 2025 DGA? What are we hoping for in the upcoming 2025 Dietary Guidelines? This timely discussion brings both hope and urgency as they address the question: Will the next guidelines reflect the latest research or continue to steer us in the wrong direction? Expert Featured: Nina Teicholz X: @bigfatsurprise IG: @ninateicholz Substack: https://unsettledscience.substack.com/ Publications Mentioned Scientific Report of the 2025 Dietary Guidelines Advisory Committee https://www.dietaryguidelines.gov/2025-advisory-committee-report Redesigning the Process for Establishing the Dietary Guidelines for Americans. https://www.ncbi.nlm.nih.gov/books/NBK469833/ Report: Nearly Half of Dietary Guidelines Advisory Committee Have Conflicts of Interest https://usrtk.org/investigations/dietary-guidelines-advisory-committee-conflicts/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Learn how Continuous Glucose Monitors (CGMs) can transform your metabolic and mental health. In this video, we dive into the benefits and debates surrounding CGMs, highlighting their role in managing blood sugar, making informed lifestyle choices, and enhancing overall well-being. *Key Topics Covered* • What are Continuous Glucose Monitors (CGMs)? • How CGMs can help improve metabolic health • Important considerations and potential drawbacks of using CGMs • Tips for getting the most out of your CGM experience Whether you're new to CGMs or already using them, this is your guide to understanding their impact on your health journey. Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Insulin#CGM

Dr. Bret Scher interviews Dr. Jack Gilbert—renowned microbiome scientist, author of Dirt Is Good, and featured expert in the Netflix documentary Hack Your Health—to explore the profound connections between the microbiome, metabolism, mental health, and overall wellness. Dr. Gilbert shares cutting-edge insights into how the 40 trillion microbes in our gut influence everything from inflammation to brain health, and how personalized strategies may hold the key to treating chronic illnesses and improving quality of life. What You'll Learn The role of the microbiome in metabolic and mental health How diet and lifestyle shape your gut bacteria Surprising links between exercise, mitochondria, and the microbiome Emerging research on fecal transplants and their transformative potential Why personalized nutrition might be the future of healthcare Experts Featured Dr. Jack Gilbert X: @gilbertjacka LinkedIn: https://www.linkedin.com/in/drjackagilbert/ Gilbert Lab: https://gilbertlab.ucsd.edu/ Dirt is Good: https://www.amazon.com/Dirt-Good-Advantage-Childs-Developing/dp/1250132606 Hack Your Health: https://www.netflix.com/title/81436688 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Dr. Bret Scher interviews Dr. Josef Witt-Doerring, a board-certified psychiatrist who specializes in tapering and deprescribing psychiatric medications. Dr. Josef combines his expertise in pharmaceutical safety, clinical psychiatry, and metabolic therapies to help patients safely transition off long-term medications. Topics Covered Life-Changing Outcomes Discover how Dr. Josef’s holistic methods have empowered individuals like Trudy, who transitioned from years of debilitating medications to pursuing a career in medical school through targeted dietary and metabolic interventions. Rethinking Psychiatric Medications Dr. Josef discusses the complex nature of antidepressants, antipsychotics, and mood stabilizers. Learn how their effects can mask symptoms without addressing root causes and the challenges of long-term use, including tolerance, side effects, and withdrawal. The Role of Metabolic Therapies Hear about the surprising success stories of patients who used dietary changes like ketogenic or gluten-free diets to overcome severe mental health conditions, reduce medication reliance, and regain their quality of life. Deprescribing in Practice Dr. Josef shares his patient-led approach to tapering medications, including practical tips on dosage reduction, liquid formulations, and the importance of balancing withdrawal risks with ongoing medication effects. Dr. Josef’s message challenges conventional psychiatry by prioritizing patient-centered care and exploring innovative therapies that focus on the root causes of mental health challenges. This conversation provides hope and practical insights for individuals and clinicians navigating the complexities of psychiatric medication. Experts Featured Dr. Josef Witt-Doerring Taper Clinic https://taperclinic.com/dr-josef-witt-doerring/ X: @taperclinic Instagram: https://www.instagram.com/taperclinic/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #MetabolicPsychiatry#KetogenicMetabolicTherapy #KetogenicTherapy#KetoForMentalHealth#Keto#TaperingMedications #Deprescribing

In this interview with Dr. Bret Scher, Dr. Corinde Wiers, Assistant Professor of Psychiatry at the University of Pennsylvania, unveils her groundbreaking research on using ketogenic therapy to treat alcohol use disorder (AUD). Dr. Wiers dives into how ketones, as an alternative energy source, may alleviate withdrawal symptoms, reduce cravings, and transform the landscape of addiction recovery. This conversation covers: The science of brain energy metabolism and how ketones are preferred over glucose in AUD. Results from clinical trials, including reductions in withdrawal severity and the need for benzodiazepines. Neuroimaging data that shows how ketogenic diets affect the brain's reward system and craving mechanisms. The broader implications of metabolic therapies for treating mood disorders, addiction, and brain health. Dr. Wiers shares her journey from studying alcohol use disorders in Europe to leading cutting-edge research in the U.S. She provides insights into the challenges and opportunities of integrating metabolic therapies into mainstream mental health and addiction treatment. Experts Featured Dr. Corinde Wiers X: @CorindeW LinkedIn: https://www.linkedin.com/in/corinde-wiers-479a9219/ https://www.med.upenn.edu/csa/corindewiers.html Resources: Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents https://pubmed.ncbi.nlm.nih.gov/33837086/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis #AlternativeTreatment #PsychiatricMedication#KetogenicTherapy #KetoforAlcoholUseDisorder #AlcoholUseDisorder

Join us as we delve into the transformative potential of metabolic psychiatry with Dr. Scott Fears, MD, PhD, Chief Medical Officer at Amae Health. In this comprehensive interview, Dr. Fears explores how ketogenic therapy, dietary adjustments, and personalized metabolic approaches are reshaping mental health treatment. He discusses ketosis as a therapeutic tool, its impact on mood and cognitive stability, deprescribing medications, and the potential of "food as medicine" to support mental well-being. Whether you're a mental health professional, someone exploring alternative mental health treatments, or simply interested in the intersection of nutrition and mental health, this interview offers valuable insights into metabolic psychiatry's potential to create a new standard for mental health care. Experts Featured Scott Fears, MD, PhD Chief Medical Officer, Amae Health https://www.linkedin.com/in/scott-c-fears-99b8b14/ https://amaehealth.com/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #KetogenicTherapy#KetoForMentalHealth #Alzheimers#Dementia#Keto

In this video, we tackle a common misconception: that losing weight alone will make you healthier. Contrary to popular belief, simply reducing the number on the scale may not lead to better health outcomes. Instead, it's crucial to focus on losing fat mass, maintaining or building lean mass like muscle and bone, and improving your overall metabolic health. We dive deep into how medications like Wegovy and Ozempic—while popular for weight loss—don't differentiate between fat and muscle loss, which can be crucial for long-term health. We'll also explore the growing evidence supporting ketogenic diets for their ability to promote fat loss while preserving muscle mass, making them a compelling option for improving body composition. Watch this video to understand how optimizing your body composition, rather than just losing weight, can lead to sustainable health benefits. *Papers Mentioned* _Once-Weekly Semaglutide in Adults with Overweight or Obesity_ https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 _Body Composition Changes After Very-Low-Calorie Ketogenic Diet in Obesity Evaluated by 3 Standardized Methods_ https://academic.oup.com/jcem/article/102/2/488/2972058?login=false _Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial_ https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2019.00348/full *Resources* Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#Ozempic #BodyRecomposition #KetoWeightLoss

In this video, psychiatrist Dr. Lori Calabrese provides essential guidance on medication management, focusing on the nuanced process of tapering and deprescribing psychiatric medications. As individuals seek alternatives or adjustments to their mental health treatments, understanding how to navigate medication changes safely is critically important. Dr. Calabrese discusses the complexities involved in reducing or discontinuing medications and covers crucial topics like personalized tapering strategies, the risks and benefits of deprescribing, and how to manage potential withdrawal symptoms. If you or someone you know is contemplating changes to their psychiatric medication, this video provides valuable insights into how to approach this sensitive process. With a focus on achieving stability and well-being, Dr. Calabrese’s approach to medication management is grounded in safety, compassion, and careful planning. *Experts Featured* Lori Calabrese, MD Board-certified Psychiatrist, Innovative Psychiatry https://www.loricalabresemd.com/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #KetogenicTherapy#KetoForMentalHealth#MedicationTapering#PsychMeds

How does the food we eat impact the way our bodies absorb and metabolize medications? What do we have to be aware of if we are eating a low-carb, high-fat ketogenic diet, and how it’s going to impact so many of the medications people with mental illness are taking? In this engaging interview with psychopharmacology expert Dr. Deanna Kelly, you’ll learn how the food you eat can influence the effectiveness of mental health medications such as Cobenfy and the extended-release form of Quetiapine, where absorption rates are affected by high-fat meals. Dr. Kelly shares valuable insights on optimizing psychiatric care with individualized approaches, revealing practical tips for patients and practitioners alike. This conversation is essential viewing for those interested in the latest strategies in metabolic psychiatry and the powerful role of nutrition in mental health care. *Experts featured* Deanna L. Kelly, PharmD, BCPP https://www.medschool.umaryland.edu/profiles/kelly-deanna/ X: @ProfDeannaK https://www.linkedin.com/in/deanna-l-kelly-pharmd-bcpp-3a8b299b/ *Related Publications* _Dietary Influence on Drug Efficacy: A Comprehensive Review of Ketogenic Diet–Pharmacotherapy Interactions_ https://pmc.ncbi.nlm.nih.gov/articles/PMC11054576/ *Related Videos* https://youtu.be/tzPlQ6dJwe8 *Sign Dr. Christopher Palmer’s Petition to Reinstate the Study* https://bit.ly/3Ap8Oe4 About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetogenicMetabolicTherapy #NutritionalKetosis#KetogenicTherapy#Depression#Schizophrenia#Keto#PsychMeds

Are you using a ketogenic diet for therapy and need to know the ideal ketone levels for success? In this video, we explain how to measure ketone levels to optimize your ketogenic diet for managing psychiatric disorders, type 2 diabetes, dementia, and other metabolic conditions. One of the unique benefits of a ketogenic diet is the ability to precisely track your body's response. But what should your target ketone level be? We tackle the most common questions and provide insights on how to set and achieve your optimal ketone level for the best therapeutic outcomes. Whether you're new to ketogenic therapy or looking to fine-tune your approach, this video offers valuable guidance to help you make the most of your ketogenic journey. *Related Videos* https://youtu.be/Hja4VURshKA?si=Pb3oRkz346PIQIrg https://youtu.be/4iMXUpLYLkk?si=cflmb65ApVjVXmzw https://youtu.be/l5j4YMkPUU8?si=X5yLzia5izONBZv9 *Studies Mentioned* _Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study_ https://link.springer.com/article/10.1007/s13300-018-0373-9 _Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial_ https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2019.00348/full _Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial_ https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub *Note* - Publication of the following study is pending. The link below is to a pre-print. _A Pilot Study of a Ketogenic Diet in Bipolar Disorder: Clinical, Metabolic and Magnetic Resonance Spectroscopy Findings_ https://www.medrxiv.org/content/10.1101/2023.10.23.23297391v2 *Resources* Metabolic Mind’s Familes & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#KetoneLevels#KetoForMentalHealth#Ketosis

In this insightful interview, Dr. Marty Makary speaks candidly about pressing issues within the U.S. healthcare system. He addresses how current debates often divert attention from core challenges, framing healthcare as a divisive landscape when the real focus should be on patient-centered care and meaningful provider support. Dr. Makary calls on policymakers and leaders to look past polarizing discussions and work toward reforms that prioritize quality, accessibility, and integrity in practice. Watch as he delves into the testimony of healthcare professionals and advocates who, for the first time, shared their insights directly with national leaders in a recent Senate hearing. This is a powerful moment for those committed to bridging the gap between healthcare policies and the actual needs of patients and providers. Join us for a closer look at what meaningful change could look like in our healthcare system. *Expert Featured* Martin Makary, MD, MPH X: @MartyMakary https://www.linkedin.com/in/martymakary/ _Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health_ : https://a.co/d/eQafyeh About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetogenicMetabolicTherapy #NutritionalKetosis#HealthReform#HealthPolicy

In this powerful and insightful interview, Lisa La Nasa, the founder of diaVerge Diabetes, shares her personal journey of living with type 1 diabetes for over 14 years. Despite following her doctor's advice, Lisa struggled to control her blood sugar levels—until she discovered the benefits of a low-carb, ketogenic diet. This dietary change, along with lifestyle adjustments, gave her the control and confidence she never thought possible. Lisa reflects on the life-changing impact of adopting a ketogenic diet, which empowered her to take charge of her health, and finally find an approach that managed her diabetes. Feel free to share your thoughts and experiences in the comments below, and don't forget to like and subscribe for more inspiring stories and insights on ketogenic therapy. *Featured* Lisa La Nasa Founder and CEO, diaVerge https://www.diaverge.com/ *Resources* Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#Diabetes#LowCarbDiet#DiabetesManagement

This interview highlights the latest research from a powerhouse team of Australian experts who are investigating the potential of ketogenic diets to treat serious mental illness like schizophrenia and bipolar disorder. Dr. Zoltán Sarnyai, Dr. Carlo Longhitano, and dietitian Jaymee-Leigh Swift share insights into their new randomized controlled trial, comparing the effects of a ketogenic diet with Australia's standard healthy eating guidelines. If you found this discussion insightful, don't forget to comment below with your thoughts, like the video, and subscribe for more content on the connection between diet and mental health! *Featured Study* https://nqdit.com.au/ *Experts Featured* Dr. Zoltán Sarnyai X: @ZSarnyai https://www.linkedin.com/in/zoltan-sarnyai-86555566/ Dr. Carlo Longhitano X: @doncaloger0 https://www.linkedin.com/in/calogero-longhitano-44879544/ Jaymee-Leigh Swift https://www.linkedin.com/in/jaymee-leigh-swift/ *Related Papers* _The effects of ketogenic metabolic therapy on mental health and metabolic outcomes in schizophrenia and bipolar disorder: a randomized controlled clinical trial protocol_ https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1444483/full Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#Keto#KetogenicTherapy #MetabolicHealth

In this episode, PhD researcher and fourth-year medical student Nick Norwitz returns to Metabolic Mind to discuss his recently published case series featuring ten individuals who have successfully managed their Inflammatory Bowel Disease (IBD) using a carnivore ketogenic diet. This promising approach is challenging conventional dietary norms, particularly when it comes to managing chronic inflammatory conditions. Nick delves into why this dietary intervention may offer significant therapeutic benefits for those suffering from IBD. We also explore the broader implications of how we interpret dietary studies and the impact of IBD on mental health. Join us as we examine this hopeful new frontier in metabolic health and what it could mean for those battling severe IBD symptoms. *Featured Paper* _Case report: Carnivore–ketogenic diet for the treatment of inflammatory bowel disease: a case series of 10 patients_ https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1467475/full *Experts Featured* Nick Norwitz, PhD X: @nicknorwitz https://www.linkedin.com/in/nicknorwitz/ https://www.youtube.com/@nicknorwitzPhD https://staycuriousmetabolism.substack.com/ Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#IBD#Carnivore#InflammatoryBowelDisease

In this interview with Dr. Bret Scher, Dr. Mark Horowitz, a leading clinician and researcher in anti-depressant withdrawal and de-prescribing, delves into the complex world of de-prescribing anti-depressants. Dr. Horowitz shares his personal journey with antidepressant withdrawal, which led him to dedicate his career to understanding safe tapering practices. He discusses the challenges that patients face when coming off medications, the withdrawal effects often mistaken for relapses, and how the current psychiatric guidelines may fall short in helping people safely taper. Dr. Horowitz emphasizes the importance of individualized tapering plans and the need for slower, more gradual reductions in medication, challenging the traditional approach of quick tapers over a few weeks. *Key Topics Covered* • The difference between withdrawal symptoms and relapse • The effects of long-term antidepressant use • Dr. Horowitz’s personal experience with tapering off Lexapro • The role of clinicians and peer support in the de-prescribing process *Experts Featured* Dr. Mark Horowitz X: @markhoro https://markhorowitz.org/ Resources: Safe tapering resources: https://www.outro.com/ _The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs (The Maudsley Prescribing Guidelines Series)_ https://www.amazon.com/Maudsley-Guidelines-prescribing-Prescribing/dp/111982298X Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#PsychiatricMedication#KetogenicTherapy #Tapering#Deprescribing

In this insightful interview, PhD researcher Isabella Cooper dives deep into the science of ketosis and its impact on health. She discusses how it's not just about maintaining high levels of ketones but also about the quality and source of those ketones. Isabella highlights the importance of avoiding unhealthy fats and proteins like soybean oil, canola oil, and pea protein isolate while following a ketogenic diet. Discover the latest research findings on cycling in and out of ketosis and how it can influence your overall health. Learn about the molecular components that truly matter when optimizing your metabolic state and achieving sustainable health outcomes. Tune in to explore the fascinating world of metabolic health with Dr. Isabella Cooper and uncover practical tips for enhancing your ketogenic journey! *Experts Featured* Isabella Cooper, PhD University of Westminster https://www.foreveryounggroup.com/ https://www.facebook.com/bellamitochondria X: @I_mitochondria *Related Papers* _Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females_ https://www.mdpi.com/1422-0067/24/21/15621 _Ketosis Suppression and Ageing (KetoSAge) Part 2: The Effect of Suppressing Ketosis on Biomarkers Associated with Ageing, HOMA-IR, Leptin, Osteocalcin, and GLP-1, in Healthy Females_ https://www.mdpi.com/2227-9059/12/7/1553 *Resources* Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Keto#Longevity

Does eating a very low carbohydrate or ketogenic diet increase the risk of heart disease? Many healthcare practitioners might say yes, but recent evidence suggests otherwise. Contrary to popular belief, a ketogenic diet does not automatically increase cardiac risk. This video explores a new study that supports this notion, challenging misconceptions that may prevent people from using ketogenic therapy to treat conditions like diabetes, depression, bipolar disorder, and other brain-based disorders. Join us in this critical discussion and share this video with your healthcare provider to help spread awareness about the true effects of ketogenic diets on heart health. *Related Videos* https://youtu.be/jybPe48bGtY https://youtu.be/cXwpYDWS0RE *Papers Mentioned* _Impact of very low carbohydrate ketogenic diets on cardiovascular risk factors among patients with type 2 diabetes; GRADE-assessed systematic review and meta-analysis of clinical trials_ https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-024-00824-w _Effect of carbohydrate-restricted dietary interventions on LDL particle size and number in adults in the context of weight loss or weight maintenance: a systematic review and meta-analysis_ https://www.sciencedirect.com/science/article/pii/S0002916522004749 _Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study_ https://pubmed.ncbi.nlm.nih.gov/29712560/ _Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial_ https://www.sciencedirect.com/science/article/pii/S0165178124001513 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#HeartHealth#HeartDisease#Keto

In this interview, Dave Feldman, citizen scientist and founder of the Citizen Science Foundation, and Nick Norwitz, Oxford PhD and Harvard medical student, discuss their latest study, which challenges the traditional view of LDL cholesterol and its relationship to heart disease risk and metabolic health. Their research focuses on lean mass hyper-responders (LMHRs)—lean, metabolically healthy individuals on a low-carb, high-fat diet, also known as a ketogenic diet. Their findings suggest that LDL cholesterol levels may not contribute to plaque buildup in these individuals as is commonly believed in the general population. They also delve into the role of coronary CT angiograms as a powerful tool for more accurately diagnosing heart health and evaluating cardiovascular risk. This study provides new insights into the intersection of cholesterol, heart disease, and metabolic health, offering fresh perspectives on how we should rethink diet, cholesterol management, and long-term health outcomes. Watch as they break down the intersection of cholesterol levels, heart disease, and metabolic health, offering fresh perspectives on assessing cardiovascular risk in modern medicine and calling for further research. Don't miss this enlightening discussion that could change how we view diet, cholesterol, and long-term health outcomes! *Featured In This Video* Dave Feldman X: @realDaveFeldman LinkedIn: https://www.linkedin.com/in/dave-feldman/ https://citizensciencefoundation.org/ Nick Norwitz, PhD X: @nicknorwitz https://www.linkedin.com/in/nicknorwitz/ *Related Papers* _Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for a "Lean Mass Hyper-Responder" Phenotype_ https://pubmed.ncbi.nlm.nih.gov/35106434/ _Carbohydrate Restriction-Induced Elevations in LDL-Cholesterol and Atherosclerosis: The KETO Trial_ https://www.jacc.org/doi/10.1016/j.jacadv.2024.101109 _Carbohydrate restriction-induced elevations in LDL-cholesterol and atherosclerosis: The KETO Trial_ https://www.metabolismjournal.com/article/S0026-0495(24)00080-5/abstract *Related Videos* https://youtu.be/cXwpYDWS0RE Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#Keto#KetogenicTherapy #MetabolicHealth#LDL#HeartHealth

In this powerful interview, Lauren Kennedy West shares her deeply personal journey with schizoaffective disorder and how traditional medical treatments fell short in addressing the root causes of her struggles. Lauren opens up about her discovery of metabolic therapies—focusing on diet, exercise, and sleep—which have played a crucial role in her path to wellness. Despite years of living with a challenging mental illness, Lauren found that these therapies offered a way to not just survive but truly thrive. In this interview, she discusses the gaps in conventional mental health treatment, the transformative impact of metabolic approaches, and how taking control of these often-overlooked aspects of health has allowed her to regain her life. Whether you’re dealing with similar challenges or are simply curious about alternative mental health treatments, Lauren’s story offers hope and inspiration. Join us as we explore the intersection of mental health and metabolic therapies in this compelling conversation. 🔗 Watch to learn more about Lauren’s experience and the potential of metabolic therapies in treating mental illness. *Key Topics Covered* • The limitations of traditional psychiatric treatments • The role of diet, exercise, and sleep in managing mental health • How metabolic therapies helped Lauren achieve remission Don’t forget to like, comment, and subscribe for more content on mental health, metabolic therapies, and personal wellness journeys. *People Featured in This Video* Lauren Kennedy West Creator, Living Well with Schizophrenia YouTube Channel: https://www.youtube.com/@LivingWellwithSchizophrenia Twitter/X: @LWSchizophrenia Resources: Metabolic Mind’s Families & Peers page: https://www.metabolicmind.org/families-and-peers Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#SchizoaffectiveDisorder#MentalHealth#LivingWellWithSchizophrenia

Are you following a ketogenic diet or using ketogenic therapy to manage depression, bipolar disorder, schizophrenia, or other brain-based disorders? If so, you've probably heard conflicting advice about protein intake—how much is too much? In this video, Dr. Bret Scher explains how to determine the right amount of protein for your unique needs. Whether you're concerned about maintaining ketosis or just want to optimize your health, this video breaks down the science in an easy-to-understand way. *Tune in to learn* •The importance of protein on a ketogenic diet •How to measure and adjust your protein intake •Common myths and misconceptions about protein and ketosis Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Resources* Metabolic Mind’s Familes & Peers page: https://www.metabolicmind.org/families-and-peers Protein Range Chart https://www.dietdoctor.com/wp-content/uploads/2019/11/CME-Target-protein-ranges.pdf Clinician Directory: https://www.diagnosisdiet.com/directory Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Protein

Dr. Mariela Glandt is a renowned endocrinologist, ketogenic therapy expert, and CEO and Co-Founder of OwnaHealth. In this interview, Dr. Glandt shares her groundbreaking work using the OwnaHealth app to treat metabolic dysfunction, type 2 diabetes, and pre-diabetes among a Medicaid population in the South Bronx. This inspiring pilot demonstrates that health improvements can transcend socioeconomic boundaries, offering hope and tangible results to underserved communities. Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Key Highlights* • The potential of ketogenic therapy for managing chronic diseases • The affordability of a ketogenic diet • Success stories from the South Bronx • The role of the OwnaHealth app in patient treatment and monitoring *Related Article* _For Richer, for Poorer: Low-Carb Diets Work for All Incomes_ by Nina Teicholz, PhD https://www.medscape.com/viewarticle/richer-poorer-low-carb-diets-work-all-incomes-2024a1000cw5?form=fpf *Experts in this video* Dr. Mariela Glandt https://www.glandt.co.il/en/home X: @DrMarielaGlandt LinkedIn: https://www.linkedin.com/in/mariela-glandt-md-6137914/ OwnaHealth https://www.owna.health/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #MetabolicHealth#Diabetes#LowCarbDiet

In this interview, Dr. Bret Scher speaks with Dr. Elena Gross, a neuroscientist and chronic migraine sufferer turned researcher, who shares her compelling journey and innovative approach to managing migraines through metabolic therapies. Dr. Gross discusses the critical role metabolism plays in neuropsychiatric diseases and how understanding this connection has driven her academic and professional pursuits. *Key Highlights* • Personal Journey: Dr. Elena Gross' battle with chronic migraines led her to pursue a PhD in neuroscience, focusing on the root causes of migraines and how they can be addressed through nutrition, supplements, and lifestyle changes. • Metabolic Health: An in-depth discussion on how metabolic health influences brain conditions, including migraines, and the potential for metabolic interventions to offer relief. • Scientific Insights: Exploration of the metabolic processes involved in migraine development and how targeting these processes can lead to better management of the condition. • Case Studies: Dr. Gross shares her experiences with patients and the outcomes of her clinical research, including the first randomized controlled trial on exogenous ketones for migraine treatment. • Global Implications: The broader impact of metabolic therapy on managing chronic diseases and the importance of shifting medical approaches towards prevention and root cause treatment. • Micronutrient Importance: The role of micronutrients and antioxidants in supporting metabolic health and their potential to improve outcomes for those with chronic migraines. Join us for this informative conversation with Dr. Elena Gross as she delves into her decade-long experience on ketogenic therapy and its profound impact on her life and research. By the end of this video, you'll gain a deeper understanding of how metabolic health can transform migraine management and improve overall brain health. Thank you for watching! If you found this video helpful, please like, subscribe, and share it with others who may benefit. Leave us a comment to let us know your thoughts. *Experts in this video* Dr. Elena Gross https://www.drelenagross.com X: @DrElenaGross Instagram: @drelenagross LinkedIn: https://www.linkedin.com/in/dr-elena-gross-6518bb2/ Migraket: https://www.brainritual.com/ *Studies referenced* _Efficacy and safety of exogenous ketone bodies for preventive treatment of migrane: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial_ https://link.springer.com/article/10.1186/s13063-018-3120-7 _Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention_ https://www.mdpi.com/2072-6643/11/4/811 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #Research#MetabolicHealth#Migraine #MigrainRelief

In this video, Dr. Bret Scher dives into the ongoing debate: Is the Mediterranean diet or a ketogenic diet better for mental health? While both diets have shown promise in improving symptoms of depression and other psychiatric conditions, this video examines the evidence behind each and discusses their potential benefits. According to Dr. Scher, any investigation into nutritional interventions for health conditions is a step in the right direction. Diets that steer away from the Standard American Diet (SAD) by eliminating ultra-processed foods and sugar will enhance metabolic health, likely offering both physical and mental benefits. However, ketogenic therapy isn't a conventional diet; it's an impactful metabolic treatment that modifies the brain and body's energy source. It's even possible to adopt a Mediterranean keto diet. This video provides a closer examination. Key Points: ▪️Diet and Mental Health: Importance of diet in managing psychiatric symptoms. ▪️Mediterranean Diet: Evidence from interventional studies showing improved depression symptoms. ▪️Ketogenic Diet: Recent studies and patient testimonials highlighting how ketogenic therapy can put serious mental illnesses, like major depressive disorder, bipolar disorder, and schizophrenia, into complete remission. ▪️Comparison and Recommendations: Practical advice on choosing between these diets and potential next steps for patients and clinicians looking to explore dietary interventions for mental illness. ▪️Future Directions: Ongoing research and the need for head-to-head trials to determine the most effective dietary approach for mental health. Watch to Learn: ▪️How the Mediterranean and ketogenic diets impact mental health. ▪️The underlying mechanisms by which ketosis may be a powerful intervention for brain health. ▪️Practical tips for implementing dietary changes to support mental well-being. If you found this video helpful, please like, subscribe, and share with anyone who might benefit. We also love hearing from you, so leave a comment below with your thoughts and experiences! Related Resources: What is the Difference between a Keto Diet and Ketogenic Therapy? - With Dr. Bret Scher: https://www.youtube.com/watch?v=4iMXUpLYLkk&t=1s What is a Good Bipolar Diet? - With Dr. Bret Scher: https://www.youtube.com/watch?v=mK2IDpHDrqU&t=2s Studies referenced: Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients https://pubmed.ncbi.nlm.nih.gov/35873236/ A randomized controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial) https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0791-y Effect of Multinutrient Supplementation and Food-Related Behavioral Activation Therapy on Prevention of Major Depressive Disorder Among Overweight or Obese Adults With Subsyndromal Depressive Symptoms: The MooDFOOD Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/30835307/ A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED) https://pubmed.ncbi.nlm.nih.gov/29215971/ The effect of a Mediterranean diet on the symptoms of depression in young males (the "AMMEND: A Mediterranean Diet in MEN with Depression" study): a randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/35441666/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy #KetoDiet#MediterraneanDiet

Blanket statements like "carbs are good" or "carbs are bad" are misleading. In this video, Dr. Bret Scher delves into the question: Are carbs bad for your mental health? Join Dr. Scher as he explores the complex relationship between carbohydrates and mental health, particularly focusing on the potential benefits of ketogenic therapy for serious mental illnesses such as bipolar disorder, schizophrenia, and major depression. Key Highlights: -Introduction to Carbs and Mental Health: Unpacking the myths and truths about carbohydrates and their impact on brain function. -Ketogenic Therapy: An in-depth look at how ketogenic diets can serve as powerful treatments for mental illnesses, providing an alternative energy source for the brain, decreasing neuroinflammation, and improving mitochondrial health. -Scientific Insights: Detailed discussion on the metabolic processes involved and how they can affect mental health conditions where glucose metabolism is impaired. -Personal Tailoring: Thanks to technological advancements, like Continuous Glucose Monitors (CGMs), people can get a clearer picture of their individual metabolic health and glucose response, allowing them to pick the appropriate diet accordingly. By the end of this video, you'll have a clearer understanding of the nuanced role that carbohydrates play in brain health and how ketogenic therapy can potentially benefit individuals suffering from psychiatric conditions. Related videos: Does the Brain Need Carbs- With Dr. Bret Scher https://www.youtube.com/watch?v=GfR9uNXewZk What Is the Difference between a Keto Diet and Ketogenic Therapy? - With Dr. Bret Scher https://www.youtube.com/watch?v=4iMXUpLYLkk Are We Biased Toward a Keto Diet- With Dr. Bret Scher https://www.youtube.com/watch?v=FWVinguULy8 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Meet Dr. Timur Liwinski, a clinician-scientist specializing in internal medicine, metabolic health, and the gut microbiome. Currently completing his psychiatry residency, Dr. Liwinski shares groundbreaking insights on ketogenic therapy for depression in this exclusive interview with Dr. Bret Scher. Discover the impact of the ketogenic diet and microbiome on mental health, as Dr. Liwinski examines the intricate connections between dietary practices, the gut-brain axis, and mental well-being. *Key Highlights* ▪️Clinical Trial Overview: An in-depth look at Dr. Liwinski's clinical trial investigating the effects of the ketogenic diet and microbiome changes on depression. ▪️Depression and Diet: Exploring the potential benefits of the ketogenic diet for those suffering from depression, focusing on how it can provide an alternative energy source for the brain. ▪️Personal Journey: Dr. Liwinski opens up about his own struggles with depression and how adopting a ketogenic diet significantly improved his mental health. ▪️Microbiome and Mental Health: A discussion on the gut-brain axis and a reflection on whether or not fiber is as critical for gut health as many believe. ▪️Species-Adequate Diet for Humans: Dr. Liwinski shares his hypothesis that all humans should spend a significant amount of time in ketosis to optimize health. ▪️Spirituality and Diet: The role spirituality and personal beliefs about what food is good for health might have on overall well-being. By the end of this interview, you'll gain a deeper understanding of how research on the ketogenic diet and microbiome can potentially revolutionize the treatment of depression and improve mental health outcomes. *Expert featured in this interview* Dr. Timur Liwinski https://www.linkedin.com/in/timur-liwinski-293b96138/ [email protected] Study referenced: _Ketogenic Diet for Depression_ https://clinicaltrials.gov/study/NCT06105762 Related videos: _Oxford’s Keto for ADHD & Depression Randomized Controlled Trial - with Ally Houston_ https://www.youtube.com/watch?v=sUAbqXcSAzg _Ketogenic Therapy: How 3 Patients Put Depression and Anxiety in Remission with Dr. Lori Calabrese_ https://www.youtube.com/watch?v=EuFhJeOf2Jc _Ketosis and Depression: An inspiring personal story from Stanford's Healthcare Innovation Lab_ https://www.youtube.com/watch?v=ISosQFO06IM _Can a Medical Keto Diet Treat Depression in College Students? - with Dr. Jeff Volek_ https://www.youtube.com/watch?v=1-eb1u7SOHU _Can a Keto Diet Help People Suffering from Depression? - with Dr. Erin Bellamy_ https://www.youtube.com/watch?v=Uz3cev323EQ _Future of Precision Medicine & Nutritional Therapies for Mental Illness with Dr. Megan Kirk Chang_ https://www.youtube.com/watch?v=q_LF1gTSkxQ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy #Research#MetabolicHealth#MetabolicNeurology #KetoForDepression #DepressionTreatment

In this interview, Mary Newport, MD, discusses her groundbreaking approach to treating dementia using coconut oil and MCT oil, highlighting the role of ketones, and exploring the stories of almost 300 families who have benefited. Dr. Newport delves into the science behind coconut and MCT oils, explaining how they generate ketones, provide an alternative energy source for the brain, and offer other potential benefits for those affected by dementia and Alzheimer's disease. *Key Highlights* - Personal Journey: Dr. Newport’s experience seeing her husband’s improvement in Alzheimer’s symptoms from using coconut oil and MCT oil. - Ketones and Brain Energy: An explanation of how MCTs are converted into ketones, and how they provide an alternative energy source for the brain, particularly beneficial in conditions like Alzheimer's where glucose metabolism is impaired. - Scientific Insights: Detailed discussion on the neuroprotective effects of ketones, including reduced oxidative stress and inflammation in the brain. - Recent Publications: A new publication featuring 288 reports of caregivers using coconut oil and MCT oil showcasing the potential impact of this approach for neurodegenerative conditions currently lacking effective pharmaceutical treatments. - Global Implications: The potential impact of this discovery on the 35 million people worldwide suffering from dementia. - Ongoing Efforts: Dr. Newport’s continued dedication to advancing this field through case studies and poster presentations emphasizes the growing body of evidence supporting ketogenic therapy for brain health. *Expert featured in this interview* Dr. Mary Newport https://coconutketones.com/ Study referenced: _Ketogenic strategies for Alzheimer’s disease and other memory impairments: History, rationale, and 288 caregiver case reports_ https://esmed.org/MRA/mra/article/view/5316 Books by Dr. Mary Newport: The Complete Book of Ketones: https://a.co/d/fHFhDSK Clearly Keto: For Healthy Brain Aging and Alzheimer’s Prevention: https://a.co/d/cBewLEU Related videos: _Keto and MCT for Alzheimer's, One Doctor's Family Journey_ https://www.youtube.com/watch?v=r3-5GQfeJ68 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#AlternativeTreatment#MedicalKeto#KetogenicTherapy#MetabolicHealth#MetabolicNeurology #MCTforAlzheimers #KetoForDementia

In this interview, Maria Edwards shares how her lived-experience putting bipolar 2 disorder into remission inspired her to become a researcher in the field of metabolic therapies. Maria completed a Master’s in Clinical Nutrition and her thesis was a feasibility study that examined ketogenic therapy for patients recovering from brain injuries. She also worked on the very first study on ketogenic therapy for Post-traumatic Stress Disorder (PTSD) that is currently in the peer-review process. Despite hurdles like small sample sizes and missing data, her pilot studies lay the groundwork for future research into ketogenic therapy for brain injury and PTSD. What You'll Learn: ▪️Maria Edward’s personal journey: Maria shares how her personal experience treating bipolar 2 disorder with a medical keto diet made her want to devote her career to helping others through researching metabolic therapies. ▪️Feasibility Trials: Understand the significance of feasibility studies and how Maria's pilot trials laid the groundwork for further investigation in this field. Experts in this video: Maria Edwards Affiliated Researcher Department of Nutrition, Exercise and Sports University of Copenhagen Denmark X: @MillaEdw LinkedIn: https://www.linkedin.com/in/maria-gabriela-persdotter-edwards-7bb75aa7/ Study: _Diet-induced ketosis in adult patients with subacute acquired brain injury: a feasibility study_ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990248/#:~:text=Conclusion,the%20effect%20on%20patients'%20recovery. If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy #KetoForDepression#KetoForAnxiety#KetoResearch #KetoStudy

In this episode, Dr. Bret Scher addresses common misconceptions and concerns surrounding the long-term safety and nutritional adequacy of ketogenic diets. Dr. Scher emphasizes the importance of weighing potential risks against known benefits. For instance, psychotropic medications, despite often worsening overall physical and metabolic health, are considered beneficial because they can alleviate symptoms of serious mental illnesses. In contrast, many patients experience incredible benefits from ketogenic therapy without harmful side effects. In numerous cases, a medical keto diet can even put psychiatric conditions like bipolar disorder, schizophrenia, and major depression into complete remission. What You'll Learn: ▪️Long-Term Safety: Is it safe to maintain ketosis over an extended period? ▪️Nutritional Adequacy: Can a ketogenic diet lead to nutrient deficiencies or disordered eating habits? ▪️Fiber and Phytonutrients: Are fiber intake and phytonutrients compromised on a ketogenic diet? ▪️Heart Disease Risk: Is there an increased risk of heart disease with long-term ketosis? ▪️Short-Term vs. Long-Term Outcomes: Is ketosis only effective for short-term outcomes? There is a lot of information circulating online touting the risks of long-term ketogenic diets that is completely unfounded. Dr. Scher tackles these prevalent questions, analyzing scientific evidence and dispelling myths surrounding ketogenic diets. Related Resources: Does Keto Cause Heart Disease? https://www.youtube.com/watch?v=pKmNhQbtDLI&t=6s Studies Referenced: _Ketogenic Diet Intervention on Metabolic and Psychiatric Health in Bipolar and Schizophrenia: A Pilot Trial_ https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub _The Ketogenic Diet for Refractory Mental Illness: A Retrospective Analysis of 31 Inpatients_ https://pubmed.ncbi.nlm.nih.gov/35873236/ If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Discover groundbreaking insights from Dr. Lori Calabrese, a Connecticut-based psychiatrist, who recently published a case series demonstrating the complete remission of depression and anxiety in three patients through ketogenic interventions. Dr. Calabrese's case studies offer a "slice of real life," highlighting patients with multiple comorbidities, which is more common than not. She explains how ketogenic therapy can lead to full remission of depression and anxiety, enabling patients to become their best selves, which is rarely achieved with standard-of-care treatments. In this video, Dr. Calabrese and Dr. Bret Scher delve into the details of her findings, showcasing how a ketogenic diet offers a promising alternative to traditional antidepressant medications. 🔍 In This Episode: Introduction to Dr. Lori Calabrese's work and her recent publication. Discussion on the effectiveness of ketogenic interventions compared to FDA-approved antidepressants. Discussion of tracking metabolic markers in psychiatric patients. Detailed case studies illustrating the impact of diet on mental health. 📢 Key Takeaways: Ketogenic diets can lead to rapid and sustained remission of depression and anxiety. Potential for dietary interventions to complement or surpass traditional psychiatric treatments. The importance of exploring metabolic approaches in mental health care. Experts in this episode: Lori Calabrese, MD https://www.loricalabresemd.com/ Founder and Medical Director of Innovative Psychiatry Twitter @loricalabresemd https://www.linkedin.com/in/loricalabresemd/ Studies mentioned: Complete remission of depression and anxiety using a ketogenic diet: case series https://www.frontiersin.org/articles/10.3389/fnut.2024.1396685/full If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this interview, Julie Milder, PhD, the director of neuroscience at Baszucki Group, discusses the groundbreaking research being done at the intersection of metabolism and mental health, including 13 clinical trials across eight institutions for ketogenic therapy for serious mental illness. Join us as Dr. Milder explains the importance of flexibility in scientific research, the unique opportunities provided by philanthropic funding, and the Baszucki Group's vision for the future of metabolic psychiatry. 🧑🏻‍🔬 Learn about the current state of the research: https://www.metabolicmind.org/research 🧠 Key Topics Discussed: The role of philanthropy in advancing scientific research The need for research that elucidates the underlying mechanisms of ketogenic therapy The flexibility and risks in funding innovative projects The need for patient-focused, treatment-first approaches The importance of supporting young investigators The vision for integrating metabolic health into psychiatric care The future of multi-site trials and large-scale research collaborations Expert Interviewed: Baszucki Group Director of Neuroscience, Julie Milder, PhD https://www.linkedin.com/in/juliemilder/ 🔗 Related Links: https://baszuckigroup.com/ https://baszuckigroup.com/news/baszucki-group-announces-columbia-universitys-martin-picard-phd-as-inaugural-recipient-of-1-5-million-baszucki-prize-in-science 📢 Stay Connected: Subscribe for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Follow us on X: @Metabolic_Mind Connect with us on LinkedIn: https://www.linkedin.com/company/metabolicmind/ 👥 Join the Conversation: Share your thoughts in the comments below! Have questions? Drop them in the comments. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice or establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #BipolarTreatment #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#Science#Research#Psychiatry

There is an escalating crisis of metabolic dysfunction in our youth, with growing rates of obesity, diabetes, and mental illness. Is it safe to use ketogenic therapy in children and teens for better management or reversal of these conditions? Dr. Matthew Calkins, an early career physician board certified in family and obesity medicine, argues it is. A 2023 paper published in the American Academy of Pediatrics (AAP) exaggerates risks associated with a ketogenic diet in pediatric patients. It also conflates a keto diet for epilepsy with a well-formulated keto diet that can be used to treat obesity, diabetes, and mental health conditions. Dr. Calkins co-authored a rebuttal paper in the Journal of Metabolic Health. In this interview, Dr. Calkins shares more about the paper, as well as some of his experiences running a metabolic clinic at Atrium One Health. He shares his clinical, science-based perspective that ketogenic diets are nutrient-rich (not deficient) and that there is no evidence they trigger eating disorders. He helps patients of all ages make lifestyle changes and improve their health. He loves seeing them achieve dramatic outcomes like reducing BMI or being able to get off insulin. Seeing the explosion of research on ketogenic therapy for a variety of health conditions, Dr. Calkins is optimistic about the future of healthcare. Experts in this video: X: @MattCalkinsMD https://www.wakehealth.edu/providers/c/matthew-william-calkins Related Resources: Carbohydrate reduction for metabolic disease is distinct from the ketogenic diet for epilepsy https://journalofmetabolichealth.org/index.php/jmh/article/view/95 Low-Carbohydrate Diets in Children and Adolescents With or at Risk for Diabetes https://publications.aap.org/pediatrics/article/152/4/e2023063755/193955/Low-Carbohydrate-Diets-in-Children-and-Adolescents?autologincheck=redirected Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #KetogenicMetabolicTherapy #NutritionalKetosis#MedicalKeto#KetogenicTherapy #KetoDiet#KetoForPediatrics#KetoForDiabetes#KetoForObesity#KetoForKids

At Metabolic Mind, we emphasize that ketogenic therapy for psychiatric disorders like bipolar disorder, schizophrenia, and major depression should be done with oversight from a clinician trained in metabolic therapies. Sometimes patients and their families voice frustration because it can be challenging to access metabolic psychiatry care. While ideally, every patient would have help from a clinician trained in medical keto for mental health, we know that this is not currently possible for many people. In this video, Dr. Bret Scher and Hannah Warren discuss why Metabolic Mind recommends that patients work with a clinician trained in metabolic therapies for mental illness, as well as some options patients might want to consider if they cannot find one, but still want to implement medical keto. This article goes into depth on the subject and links to a variety of resources: https://www.metabolicmind.org/blog/can-patients-do-ketogenic-therapy-for-a-psychiatric-condition-without-the-help-of-a-metabolic-psychiatrist Related Resources: If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Can a Keto Diet Cause Hypomania and How Can It Be Avoided? https://www.youtube.com/watch?v=F11ZBvCjVNk&t=1s Tapering Psychiatric Medications on Keto https://www.youtube.com/watch?v=dUy_1VW797k&t=1s Labs to Check Before Starting Ketosis for Mental Health: https://www.youtube.com/watch?v=tSkOw3l8OoQ&t=2s List of labs: https://www.dropbox.com/scl/fi/j1qeg7acwrkzrpx2hv5g2/john-doe-own-your-labs2_with_crp.pdf?rlkey=6kavz4fpk91s8moilgfm91qws&e=2&st=wnoqxk5r&dl=0 Information sheet that explains ketogenic therapy and the research to date that patients can take to their clinician: https://www.dropbox.com/scl/fi/2dr78g0kny2n5raguk7jc/Scientific-and-Clinical-Rationale-for-KD-in-MH.pdf?rlkey=v7z3ng7py73ac90fokkk86mqj&e=1&st=dr3d3872&dl=0 Living Well With Schizophrenia, Keto and Metabolic Health Program 2024: https://www.youtube.com/playlist?list=PLDgFtG7YA9Y7mRUzd2vuBU7lCC6CpLk1N The research on ketogenic therapy for mental illness: https://www.metabolicmind.org/research Clinician and medical keto expert provider directory: https://www.metabolicmind.org/families-and-peers#directory Medical keto for mental illness peer support group: https://www.meetup.com/keto-lifestyle-for-mental-health/ Medical Keto Group Programs - Nicole Laurent, LMHC: https://mentalhealthketo.com/brain-fog-recovery-program/ - Erin Bellamy, PhD (group programs starting July 2024) https://www.ikrt.org/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#AlternativeTreatment#MedicalKeto#KetogenicTherapy#KetoforBipolar#KetoforSchizophrenia

Ketosis is a therapeutic physiologic state induced by eating a keto (reduced-carb) diet that can treat, and often reverse, a wide range of illnesses from type 2 diabetes, to psychiatric conditions like bipolar disorder, depression and schizophrenia. A medical keto diet can be a very powerful intervention, but, sometimes, people are told that their other health conditions, such as gout or high LDL cholesterol, would make following a keto diet unsafe. In most cases, even with other health conditions, ketogenic therapy can be highly beneficial. In this video, Dr. Bret Scher goes over some of the most common conditions that many people falsely believe would interfere with safe implementation of a keto diet, including: gallbladder removal, bariatric surgery, gout, high cholesterol and heart disease. He explains that following a keto diet with these conditions is, in fact, safe, if approached in the right way with clinical supervision. Watch What Is the Difference between a Keto Diet and Ketogenic Therapy? - With Dr. Bret Scher: https://www.youtube.com/watch?v=4iMXUpLYLkk Watch LDL Risks and Benefits of Ketogenic Therapy- with Dr. William Cromwell: https://www.youtube.com/watch?v=jybPe48bGtY Ketogenic Therapy in Patients With Pre-existing Medical Conditions: https://www.dietdoctor.com/low-carb/for-doctors/difficult-cases If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources: https://www.metabolicmind.org/families-and-peers Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalIllness#MedicalKeto#KetogenicTherapy #KetoDiet#AntiKeto#KetoSafety