Season 1 · Episode 29
S1E29: Acetyl CoA, Citrate, and the Metabolic Merry-Go-Round
Meta Health: Mindfulness Meets Metabolism · Ronesh Sinha, MD
July 6, 202334m 15s
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Show Notes
I've selected 2 key metabolic ingredients, Acetyl CoA and Citrate, to explain nutrition metabolism in further detail. I've also selected a different storyline, the mitochondrial amusement park and the Kreb's merry-go-round, to help you visualize some of the most fundamental steps of metabolism. In this episode we cover:
- Acetyl CoA's role as a key metabolic conductor
- The metabolic merry-go-round used to explain Kreb's cycle
- The importance of the Citrate sensor in switching between anabolism and catabolism
- How these concepts are tied to the root cause for weight gain and insulin resistance
- A critique of B-vitamin supplements as "energy producers"