Season 1 · Episode 25
S1E25: The Critical Pentose Phosphate Pathway and Erythritol
Meta Health: Mindfulness Meets Metabolism · Ronesh Sinha, MD
March 14, 202332m 33s
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Show Notes
The pentose phosphate pathway, which I refer to as P3, is one of my favorite metabolic pathways and one that gets far less attention than glycolysis, gluconeogenesis, and Krebs, yet plays such a key role in our body. In this episode we go over the following:
- Brief refresher on glycolysis and coenzymes using James Bond storytelling
- Deeper dive into oxidation, reduction, and free radicals (aka reactive oxygen species or ROS)
- Understanding and remembering the key functions of P3
- How P3 is tied to obesity, insulin resistance, heart disease, and cancer
- How erythritol is tied to P3 and the fallacy of a study linking it to heart disease