Episode 96
096: HIV interaction with the immune system with Mark Connors
Meet the Microbiologist · Julie Wolf, Mark Connors
November 30, 201847m 53s
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Show Notes
A very small proportion of people infected with HIV do not develop AIDS. Mark Connors talks about 2 patient populations that his lab studies, the elite controllers and the elite neutralizers, who control HIV infection with their respective T cell or B cell responses. Connors hopes his work on killer T cells and broadly neutralizing antibodies will help scientists develop better HIV therapies or an effective HIV vaccine.
Links for This Episode:
- Mark Connors labsite at NIAID
- Immunity article: Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth.
- Immunity commentary: Class II-restricted CD8s: New lessons violate old paradigms.
- Science article: Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
- Imagining an HIV-Free Future (Smithsonian Worlds AIDS Day Event (Live Dec 4th at 6:45pm)
- HOM Tidbit: 12 Diseases that Changed Our World
- MTM Listener Survey