Mayo Clinic Health Matters

Summer and fall are going to be a dangerous time for people in the U.S. who have not been vaccinated for COVID-19, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "I really think this exponential rise in the number of sequences that are delta must be taken seriously," says Dr. Poland. "We are seeing a surge again, in hospitalizations in the UK, because of the delta variant in people who have not been vaccinated or who only got one dose of vaccine. This is a really critical message for the public to hear because in the U.S. we are stalled in vaccination rates." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about a possible COVID-19 surge and being emotionally ready for the pandemic to be over. He also answers listener questions about COVID-19 reinfection, the latest on antiviral development for COVID-19, and the latest news about COVID-19 vaccines affecting menstrual cycles and sperm quality.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

June is Pride Month, which is celebrated annually to honor the 1969 Stonewall riots, and the impact that lesbian, gay, bisexual, transgender, gender queer and gender nonconforming people have had on history. LGBTQ people often experience barriers to accessing health care and preventive services, which can result in disparities in both cancer risk and treatment. "Many of those disparities are rooted in stigma and discrimination that have really historically been an issue for this population," says Dr. Jewel Kling, chair of the Division of Women's Health in the Department of Internal Medicine at the Mayo Clinic in Arizona. On the Mayo Clinic Q&A podcast, Dr. Kling discusses cancer screening, prevention and treatment for LGBTQ people, and the importance of finding a trusted healthcare provider. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

When it comes to technology, Mayo Clinic is a leader in bringing the tools and science of artificial intelligence, or AI, into practice. In health care, AI is simply a way of programming a computer to process and respond to data for better patient outcomes. Mayo's AI work in Cardiovascular Medicine uses computer algorithms applied to EKG to aid in early risk prediction and diagnosis of serious and complex heart problems. Early applications have used AI and EKG technology to show the difference between numerical and biological age, to screen for atrial fibrillation, and to detect a weak heart pump before a patient is symptomatic. "The use of AI will help us detect diseases earlier, so that we can begin treatment sooner, and can better utilize health care resources," says Dr. Paul Friedman, chair of the Department of Cardiology at Mayo Clinic. On the Mayo Clinic Q&A podcast, Dr. Friedman discusses the latest research and applications for using AI in cardiology. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices is holding an emergency COVID-19 meeting this week to discuss COVID-19 vaccine safety as it relates to news that young people may develop myocarditis after receiving a second dose of a messenger RNA COVID-19 vaccine. Myocarditis, which is an inflammation of the heart muscle, is usually caused by a viral infection. But it can result from a reaction to a drug or be part of a more general inflammatory condition. Signs and symptoms include chest pain, fatigue, shortness of breath and arrhythmias. "There have been about 789 cases reported," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And that can happen for a whole variety of reasons." In this Mayo Clinic Q&A podcast, Dr. Poland details the concerns about the myocarditis reports. He also discusses the latest news on the COVID-19 delta variant, and he explains what scientists are calling the "two-track pandemic."Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Last week, the Food and Drug Administration approved aducanumab to treat Alzheimer’s disease, which is a progressive brain disorder that is the most common cause of dementia. Aducanumab targets amyloid plaques in the brain that are believed to be an essential component of Alzheimer’s disease. But what does the approval of a new Alzheimer's drug mean for patients? On the Mayo Clinic Q&A podcast, Dr. Ronald Petersen, a Mayo Clinic neurologist and director of Mayo Clinic’s Alzheimer’s Disease Research Center, and Dr. David Knopman, a Mayo Clinic neurologist, discuss the challenges ahead to identify the appropriate patients for treatment with aducanumab. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Many people may be living with a serious heart condition and not know it. Because the signs and symptoms of atrial fibrillation can be vague, people often think they are simply out of shape or just getting older. Atrial fibrillation, sometimes referred to as "a-fib", is an irregular and often rapid heartbeat that can increase the risk of strokes, heart failure and other cardiac problems. During atrial fibrillation, the heart's two upper chambers — the atria — beat chaotically and irregularly, and out of coordination with the two lower chambers — the ventricles. Atrial fibrillation symptoms often include heart palpitations and shortness of breath. Treatments for atrial fibrillation can include medications and other interventions that try to alter the heart's electrical system. "Patients really do feel tremendous improvement in their quality of life when we keep them in normal rhythm," says Dr. Christopher DeSimone, a Mayo Clinic cardiologist who specializes in cardiac electrophysiology. On the Mayo Clinic Q&A podcast, Dr. DeSimone discusses symptoms, diagnosis and treatment of atrial fibrillation. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Children are always watching and learning behaviors from those around them, and parents are usually a child's first role model. But when it comes to discussing racism with children, parents and caregivers may wonder how to begin the conversation about race and bias, and what is age-appropriate to discuss with their children. The American Academy of Pediatrics offers these three strategies for helping children understand and deal with racial bias: Talk to your children and acknowledge that racial differences and bias exist. Confront your own bias and model how you want your children to respond to others who may be different than them. Encourage your children to challenge racial stereotypes and racial bias by being kind and compassionate when interacting with people of all racial, ethnic, and cultural groups. This edition of the Mayo Clinic Q&A podcast, which focuses on the importance of discussing racism with children, features an #AsktheMayoMom episode hosted by Dr. Angela Mattke, a pediatrician at Mayo Clinic Children's Center. Joining Dr. Mattke is Dr. Nusheen Ammeenuddin, chair of Diversity and Inclusion for Mayo Clinic Health System and chair of the American Academy of Pediatrics' Council on Communications and Media. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that." In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?"Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

June is National Cancer Survivor Month, and National Cancer Survivors Day was recognized on Sunday, June 6. Both events recognize and celebrate the millions of adults and children in the United States who have experienced a cancer diagnosis. According to the National Cancer Institute, there are nearly 17 million cancer survivors in the U.S. Each one experiences cancer survivorship differently. Sometimes cancer survivorship means a cure. Sometimes it means living with the cancer. In other cases, survivorship involves a new normal that requires adapting to the permanent side effects of cancer treatment. Cancer survivorship is as unique as each cancer survivor. On this Mayo Clinic Q&A podcast, Dr. Kathryn Ruddy, associate director of Patient and Community Education and co-chair of the Symptom Control/Survivorship Cross-Disciplinary Group at Mayo Clinic Cancer Center, discusses the needs and concerns of cancer survivors of all ages. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The use of telehealth during the COVID-19 pandemic rose dramatically across the nation, including at Mayo Clinic. Telehealth has provided safe, convenient access to health care for people who needed to stay home to follow guidelines for social distancing and quarantines. Recent studies conducted by the COVID-19 Healthcare Coalition found that patients and providers are highly satisfied with digital health care as a way to deliver care. The results of the patient survey mirrored the results of the provider survey released last fall. Of the 2,007 patients across the U.S. who responded to the survey, 79% indicated that they were satisfied with their telehealth visit and 73% expect to continue with telehealth care in the future. “The experience with telehealth during the COVID-19 pandemic has opened everyone’s eyes as the potential to deliver healthcare in much more safe and convenient ways," says Dr. Steve Ommen, medical director of Experience Products for Mayo Clinic's Center for Digital Health. "I think that years from now, we will point to 2020 as the year that the potential of digital care delivery became a reality, as long as the regulatory and reimbursement environment is conducive to its growth." On the Mayo Clinic Q&A podcast, Dr. Ommen discusses how telehealth is becoming part of the new normal in health care. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Cerebrospinal fluid is the clear fluid that surrounds the brain and spinal cord. It cushions the brain and spinal cord from injury, delivers nutrients and acts as a waste removal system for the brain. A cerebrospinal fluid leak occurs when fluid escapes through a small tear or hole in the outermost layer of tissue that surrounds the brain or the spinal cord. Leaks can occur in the skull or at any point along the spinal column. Because headache is a common symptom, patients are often misdiagnosed or mistreated for migraines. "About 85% of patients with a cerebrospinal fluid leak at the level of the spine will have an orthostatic headache — one that gets worse when they stand up and better when they lie down," says Dr. Jeremy Cutsforth-Gregory, a Mayo Clinic neurologist. Once properly diagnosed, a blood patch procedure is often an effective treatment for spinal cerebrospinal fluid leaks. The patient's own blood is injected into the spinal canal, and the blood clot that forms can stop the leak. In other patients, surgery or a novel procedure called paraspinal vein embolization may be more appropriate. On the Mayo Clinic Q&A podcast, Dr. Cutsforth-Gregory discusses diagnosing and treating spinal cerebrospinal fluid leaks. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Regular activity is good for the heart, but patients with heart conditions may wonder if it is safe to exercise. Mayo Clinic's Sports Cardiology Clinic is a specialty clinic where a team of cardiologists, exercise physiologists, and other specialists evaluate and treat heart conditions with a goal of keeping athletes active in sports. But who could benefit from sports cardiology? "We're trying to target three different types of patients," says Dr. Brian Shapiro, a Mayo Clinic cardiologist. "Of course, that elite athlete, whether it be professional, collegiate or even high school, as we're able to see patients from 15 years and older. Second, the weekend warriors — people who want to get out there and start running again, or biking, doing triathlons and things of this nature. And, finally, those patients who may actually have cardiac disease and have never worked out." The Sports Cardiology Clinic also can advise patients how to improve training and performance. The evaluation involves a stress test. "A cardiopulmonary stress test is the cornerstone of the evaluation we will do with these patients," says Dr. Bryan Taylor, a Mayo Clinic cardiopulmonary exercise physiologist. "We are trying to do two things. One, we're trying to understand the baseline level of fitness of the overall heart and lung and musculoskeletal fitness the person has. But the stress test is also a first sweep where potential issues might be identified. And we can understand if exercise is limited, is it due to a heart condition or a lung condition or something else?" On the Mayo Clinic Q&A podcast, Dr. Shapiro and Dr. Taylor discuss sports cardiology evaluation, monitoring and treatment options. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The number of COVID-19 cases, hospitalizations and deaths in the U.S. continues to decline. However, cases of COVID-19 are increasing in younger populations. "It's becoming a childhood disease," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Children have composed over 16,000 hospitalizations for COVID-19 and about 300 have died." Meanwhile, each day brings fresh research news, including updates on possible side effects of the COVID-19 vaccines. "We're collecting information as we go and have data on about 4.5 million people now," says Dr. Poland. "That's larger than we would have for any other vaccine." In this Mayo Clinic Q&A podcast, Dr. Poland expands on these latest news items and puts the data in perspective. He also discusses vaccination rates, the possibility of mixing and matching vaccines for COVID-19 boosters, vaccination rates, and much more.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

A thoracic aortic aneurysm is a weakened area in the major blood vessel that feeds blood to the body. When the aorta is weak, blood pushing against the vessel wall can cause it to bulge like a balloon. This is called an aneurysm. Depending on the cause, size and growth rate, your thoracic aortic aneurysm treatment options can vary. Thoracic aortic aneurysms often grow slowly and usually without symptoms, making them difficult to detect. Thoracic aortic aneurysms are often found during routine medical tests, such as a chest X-ray, CT scan or ultrasound of the heart, sometimes ordered for a different reason. "Most of the time, a thoracic aortic aneurysm is discovered incidentally," says Dr. Gabor Bagameri, a Mayo Clinic cardiovascular surgeon. "When you find out you have an enlarged aorta, it's important to get connected to cardiology and a cardiac surgeon who has expertise and has treated a high volume of patients." On the Mayo Clinic Q&A podcast, Dr. Bagameri discusses treatment options and Mayo Clinic's multidisciplinary approach to treating thoracic aortic aneurysms. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Congenital ear anomalies or malformations are birth defects that affect the shape and position of the ear. Common anomalies include microtia, or small ears; prominent ears; or a missing ear. These malformations are not only cosmetic but also they can affect the function of the ear. Otoplasty is a surgical procedure to change the shape, position or size of the ears. This edition of the Mayo Clinic Q&A podcast features an #AsktheMayoMom episode hosted by Dr. Angela Mattke, a pediatrician at Mayo Clinic Children's Center. Joining Dr. Mattke to discuss congenital ear anomalies is Dr. Waleed Gibreel, a Mayo Clinic craniofacial and pediatric plastic surgeon. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Recent COVID-19 masking guidelines announced by the Centers for Disease Control and Prevention, continue to generate a public conversation. "The decision about masking needs to be nuanced," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Wearing a mask should be based on the risk of infection, the percentage of the population vaccinated, a person's own immune system, and then the role of vaccine variants with the durability of our immune response." In this Mayo Clinic Q&A podcast, Dr. Poland discusses masking guidelines in further detail. Also, he offers an update on COVID-19 vaccine research for children, and he shares positive news about the decreasing numbers of COVID-19 cases and deaths.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Bladder cancer is a common type of cancer that begins in the cells of the bladder, a hollow muscular organ in the lower abdomen that stores urine. Bladder cancer signs and symptoms can include blood in the urine, frequent or painful urination, and back pain. "The vast majority of bladder cancer patients are diagnosed with cancer that's not imminently life-threatening, but they tend to be aggressive," says Dr. Mark Tyson II, a Mayo Clinic urologic surgeon. "So bladder cancers, even if they're not life-threatening when they're first diagnosed, tend to recur." For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for recurrence of their cancer. May is Bladder Cancer Awareness Month. On this Mayo Clinic Q&A podcast, Dr. Tyson discusses bladder cancer diagnosis, staging and treatment. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Like many organizations, Mayo Clinic is working to address disparities and equity in health care. This work is important not only in the clinic setting, but also in addressing equity issues in medical research and clinical trials. Clinical trials are research studies used to determine whether an intervention, such as a drug, device or other therapy, is safe and effective for people. People in racial and ethnic minority groups are underrepresented in clinical trials. "That's a real concern and a real issue because you want to make sure that the results of the clinical trial are applicable to the whole population," says Dr. Gerardo Colon-Otero, a Mayo Clinic oncologist and medical director for the Center for Health Equity and Community Engagement Research at Mayo Clinic in Florida. While efforts are underway at Mayo Clinic to promote inclusive participation in clinical trials for all populations, Sonya Goins, a Mayo Clinic patient who has participated in clinical trials, says that more work needs to be done to reach members of underserved groups and help them understand the benefits of participating in clinical trials. "Firstly, when it comes to diverse communities, people need to be aware that these studies are out there, and that they give you hope," says Goins. "That's the reason why I do them. It's because they give me hope." On the Mayo Clinic Q&A podcast, Dr. Colon-Otero and Goins join host Dr. Halena Gazelka for a conversation about equity in research and clinical trials. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Children 12–15 are now eligible to receive Pfizer's COVID-19 vaccine, after the U.S. Food and Drug Administration granted emergency use approval. And there is other COVID-19 news. "This is the first week we have not had an increase in COVID-19 cases in any U.S. state, and in 33 of those states, there was a decrease last week," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "This has not happened on any consistent basis for every U.S. state since the start of this pandemic." In this Mayo Clinic Q&A podcast, Dr. Poland explains the real world effectiveness of the COVID-19 vaccines, talks about the approval process for these vaccines and answers a number of listener questions.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

On average, someone in the U.S. has a stroke every 40 seconds. A stroke occurs when the blood supply to part of the brain is interrupted, depriving the brain of oxygen. It's important to recognize the warning signs of stroke, because prompt treatment can minimize brain damage. Every moment is crucial. "Strokes commonly occur in people of all ages," says Dr. Robert Brown, Jr., chair of Mayo Clinic's Division of Stroke and Cerebrovascular Diseases. "And, so, it's very important that people know what is a stroke, what are the symptoms and what are the risk factors for stroke?" May is National stroke Awareness Month. In this Mayo Clinic Q&A podcast, Dr. Brown explains the importance of remembering the F.A.S.T. acronym to recognize a stroke: face drooping, arm weakness, speech difficulty, time to call 911. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Depression is a serious mental health problem that causes a persistent feeling of sadness and loss of interest in activities. Although depression can occur at any time in life, symptoms may differ between teens and adults. Issues such as peer pressure, academic expectations and changing bodies can bring a lot of ups and downs for teens. But for some teens, the lows are more than just temporary feelings. They are a symptom of depression. Treatment for depression depends on the type and severity of the symptoms. A combination of talk therapy and medication can be effective for most teens with depression. Friday, May 7, is National Children’s Mental Health Awareness Day. The goal is to raise awareness about the importance of mental health and highlight how positive mental health is essential to development for children and adolescents. This edition of the Mayo Clinic Q&A podcast features an #AskMayoMom episode hosted by Dr. Angela Mattke, a pediatrician at Mayo Clinic Children's Center. Joining Dr. Mattke to discuss teens and depression are Dr. Paige Partain, a Mayo Clinic pediatrician, and Hannah Mulholland, a Mayo Clinic pediatric social worker. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

COVID-19 cases are falling in the U.S. because 245 million doses of one of the available COVID-19 vaccines have been administered, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "But at the same time, there are still people who need more information about the safety and the value of getting a COVID-19 vaccine," says Dr. Poland. While still hopeful, Dr. Poland says he's concerned herd immunity won't be reached in the U.S. through vaccination. And that will mean more tragic deaths due to COVID-19 infection. "My guess is, because we're such an interconnected global community until everybody's safe, none of us are safe. And we're going to likely see continued circulation of the virus, and that virus will seek out whoever is not immune," says Dr. Poland. In this Mayo Clinic Q&A podcast, Dr. Poland also addresses when we will need COVID-19 vaccine boosters will be needed and the latest on masking guidelines from the Center for Disease Control and Prevention. Plus, he will provide an update on COVID-19 treatments and how to handle those who want to visit a newborn baby.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Primary brain tumors originate in the brain or tissues close to the brain, such as in brain-covering membranes, cranial nerves, or the pituitary or pineal glands. There are many types of primary brain tumors, and over 84,000 people will receive a primary brain tumor diagnosis in 2021, according to the National Brain Tumor Society. The median age for these diagnoses is 60. The most common cancerous, or malignant, brain tumor is the glioblastoma, a type of glioma that begins in the brain or spinal cord. The most common primary noncancerous, or benign, brain tumor is the meningioma, which arises from the membranes that surround the brain and spinal cord. May is Brain Tumor Awareness Month. On the Mayo Clinic Q&A podcast, Dr. Alyx Porter, co-chair of the Central Nervous System Tumor Disease Group at Mayo Clinic Cancer Center, discusses the various types of brain tumors and how they are diagnosed and treated. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The type of breast cancer a person has and how far it has spread determine the appropriate treatment. Previously, a patient with breast cancer might have received five to six weeks of radiation therapy. But the approach is changing. "For many years, we had the understanding that giving a little bit of radiation each day, and spreading that treatment out over multiple weeks was the gentlest on the normal tissues, and that would lead to the least side effects," says Dr. Robert Mutter, a Mayo Clinic radiation oncologist. "But over the last decade, or two, there's been a lot of research. We found we might be better off giving bigger doses each day and finishing in a shorter period of time. And that might be better at destroying the cancer cells, while limiting sides effects of the normal tissue." In this Mayo Clinic Q&A podcast, Dr. Mutter expands on the research at Mayo Clinic's research and the development of new therapies to minimize patient side effects from radiation, including the increased use of proton therapy. Dr. Mutter also talks about the patient concerns about relapses and how Mayo is using medicines in combination with radiation to reduce relapse risks. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

While the number of people being vaccinated for COVID-19 is dropping, the Centers for Disease Control and Prevention and other medical experts continue to strongly encourage people to get vaccinated for COVID-19. And that means that those who are being vaccinated with the Moderna and Pfizer COVID-19 vaccine should get their first and second doses on schedule. “About 8% of people who got their first dose have not returned for the second dose and this is concerning when you're getting close to 1 in 10," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "When you measure in the short term, one dose in a healthy person offers about 80% protection. But that's not 95% protection, like you get after two doses." In this Mayo Clinic Q&A podcast, Dr. Poland expands on why people need that second COVID-19 vaccine dose and he talks about whether people should mix and match the different COVID-19 vaccines for their second dose. He also speaks about the status of COVID-19 vaccines for young people, and he addresses listener questions about traveling, being together after vaccination, and the latest rise of additional COVID-19 variants.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

For heart-liver transplants, the liver and heart must come from the same donor, and some patients wait years to receive both organs. Also, antibodies from the donor can increase chances of the receiving patient rejecting the heart. But Dr. Sudhir Kushwaha, a Mayo Clinic cardiovascular transplant surgeon, says when a liver transplant is also involved, it sort of gives the heart protection. Now, he says, Mayo is introducing an innovative approach by transplanting the liver before the heart. "When we looked back, at our experience with our combined heart-liver patients, we made the observation that those patients really have zero rejection," says Dr. Kushwaha. "Wiith that in mind, we thought, well, what's going on here? There must be some biological process." “The antibodies seem to bind in the liver in a way that doesn't harm it — the same as it does in other organs — and it really does sort of sponge up the antibodies against that specific donor,” says Dr. Richard Daly, a Mayo Clinic cardiovascular transplant surgeon. In this Mayo Clinic Q&A podcast, Drs. Kushwaha and Daly discuss in detail this reverse transplant protocol and the research learning process of the past decade. They also discuss why some patients need this double organ transplant and they describe how the surgeries are closely choreographed with Mayo Clinic's liver transplant teams. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Has your eyesight become blurry? Do you have glaucoma, but you haven't been in for an exam or treatment? Amid the COVID-19 pandemic, many people may have delayed eye appointments. Dr. Cheryl Khanna, a Mayo Clinic ophthalmologist, says it's important to catch eye diseases early. "I think the main take-home message is that if you have decreased vision, if you have an ocular disease, it is safe to come to Mayo Clinic and receive care," says Dr. Khanna. "And if you postpone treatment, there may be irreversible vision loss." In this Mayo Clinic Q&A podcast, Dr. Khanna expands on the importance of eye care and how artificial intelligence is helping develop individual treatments for patients. She also talks about minimally invasive glaucoma procedures and newly emerging cataract technologies. And she describes several clinical trials that are underway — such as gene therapy trials for macular degeneration and retinal dystrophies. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Chronic pain is experienced by about one-quarter to one-third of children, with about 1 in 20 experiencing debilitating pain, according to the World Health Organization. Chronic pain is defined as recurrent or continuous pain lasting more than three months. For children and adolescents, adjusting to and living with pain can be overwhelming. On the Mayo Clinic Q&A podcast, a special edition of "Ask the Mayo Mom" focuses on managing chronic pain in children. Dr. Angela Mattke, a Mayo Clinic pediatrician, is joined by Mayo Clinic Children’s Center experts Dr. Tracy Harrison, medical director of the Mayo Pediatric Pain Rehabilitation Center, and Dr. Cynthia Harbeck-Weber, a Mayo Clinic child and adolescent psychologist. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group says COVID-19 mutations and the virus spread are happening because of people who don't wear masks, who don't get vaccinated and who don't adhere to safety recommendations. "I believe that we should be radically transparent and honest," says Dr. Poland. "The more time this virus passes through one person after another, the more likely it continues to mutate. As a result of those mutations, two things are happening. Some of the mutations are making vaccines and plasma monoclonal antibodies less effective. The other thing is that the virus will likely become something that we have to live with for the rest of our lives." Dr. Poland reminds people that vaccine protection is not 100%. Breakthrough infections can occur. "Remember that in the clinical trials, 95% means that compared to unvaccinated people, your risk is reduced by 95% — not 100%," he says. "You might have a mild case of COVID-19,but you can still spread it to others, including those who are immune compromised, such as cancer patients. That's why we continue to wear masks until we get very widespread immunization." In this Mayo Clinic Q&A podcast, Dr. Poland talks more about breakthrough infections and the Johnson & Johnson COVID-19 vaccine pause, and he answers listeners questions.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Mayo Clinic Laboratories has performed over 3 million COVID-19 tests. "In December 2019, there was a disease, and three months later, everyone in the country — and around the globe — wanted a test to see if they had the disease," says Dr. William Morice II, president of Mayo Clinic Laboratories. "With COVID-19, we've learned the importance of laboratory testing and diagnostic medicine in health care, both in the U.S. and globally." Dr. Morice says professionals are needed in laboratory medicine, who understand the technology and the science but also who understand the human need. "One of the strong memories for me was being in the lab late at night, and getting an email from a Native American tribal leader saying, 'We need help,'" says Dr. Morice. In this Mayo Clinic Q&A podcast, Dr. Morice speaks about the commitment, agility and resiliency of laboratory staff during COVID-19, the collaborations and partnerships with academic and private labs, and the future of testing as more COVID-19 variants emerge. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

There are many causes of head and neck cancers, and treatment is complicated. And one of the fastest growing demographic of cancers in the U.S. is human papillomavirus (HPV) in younger people, says Dr. Daniel Ma, a Mayo Clinic radiation oncologist. "This is a treatable disease," says Dr. Ma. "It's a disease that's very responsive to radiation, chemotherapy and surgery. And it's one of those diseases, because the patients are young, that there's a good cure rate." Dr. Ma says treatment for the numerous head and neck cancers requires medical coordination. "It's where tight collaboration between an ENT (ear, nose and throat) surgeon medical oncologist who gives chemotherapy, and a radiation oncologist, like myself, who gives radiation or X-ray treatments, is crucial for the success of the treatment." In this Mayo Clinic Q&A podcast, Dr. Ma describes the various symptoms and getting a diagnosis, and he talks about Mayo Clinic's Oropharynx Cancer Clinic, which he says is the first such multidisciplinary clinic in the country. Dr. Ma also explains advances in treatment like newer radiation techniques, including proton therapy, and more minimally invasive surgical techniques. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

For many people, the COVID-19 pandemic has provided an opportunity to reassess priorities in their lives, spend more time with loved ones, and take care of some projects or personal issues that they’ve been avoiding. But some people may have been avoiding their heart health. Dr. Christopher DeSimone, a Mayo Clinic cardiologist, says he's concerned some patients may have been ignoring symptoms, waiting six or nine months, or even a year, before going to in for a medical exam. "What's really heartbreaking is there are things we could have offered patients — medicines and interventions — things that we could have caught in an earlier time frame," says Dr. DeSimone. "We could have really impacted their quality of life and lessened their risk from dying of heart disease." In this Mayo Clinic Q&A podcast, Dr. DeSimone talks more about the concerns of delayed heart health care and describes heart disease symptoms. And he emphasizes how safe it is to go to the hospital for a heart check during the COVID-19 pandemic. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

As spring break travelers return home and the highly transmissible U.K. COVID-19 variant is discovered in all 50 U.S. states, the country is on the verge of a fourth COVID-19 pandemic surge. That's according to a number of health experts, including Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. However, Dr. Poland says there is some good news related to the transmission of COVID-19 on surfaces. "Wisdom resides in changing your mind and your recommendations as new data and science becomes available," says Dr. Poland. "What the Centers for Disease Control and Prevention is doing is modifying those guidelines, saying that the risk of touching a contaminated surface and then getting infected is very low." In this Mayo Clinic Q&A podcast Dr. Poland explains more about the CDC guidelines and he addresses other COVID-19 topics in the news, including recent data that says men are more vaccine-hesitant than women.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In the midst of the COVID-19 global health crisis, Mayo Clinic is changing the way patient care is provided. "I think, as an organization, we've made close to a decade of progress over the course of one year," says Mayo Clinic President and CEO Dr. Gianrico Farrugia. "The COVID-19 pandemic pushed us faster and further than we could have imagined. We're now tangibly stronger than we were pre-COVID — in our practice, in education, in research and in operation and business agility." One example, says Dr. Farrugia, has been with virtual and digital care. "We all want to see our patients in person," explains Dr. Farrugia. "But the other side of the coin is that it's important to meet patients where they are, to make health care easier for their daily lives. What we're seeing now is that we can do both physical and virtual care really well and do it seamlessly." "The pandemic served to reinforce our 2030 'Bold.Forward.' strategy, which is to cure more patients, to connect people and data, to create new scalable knowledge, and to transform health care through our unique Mayo Clinic platform," says Farrugia. In this Mayo Clinic Q&A podcast, Dr. Farrugia says, "Amidst all the grief and the loss that we all experienced, there's a lot we have gained and now it's incumbent on us to make sure we use it to transform health care." Listen as Dr. Farrugia describes how that transformation is happening at Mayo Clinic. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

When it comes to children, physical activity is important for development. Physical activity helps build strong bones and muscles and reduces the risk of developing heart disease, cancer, obesity and Type 2 diabetes. According to the Centers for Disease Control and Prevention (CDC), regular physical activity also reduces stress and anxiety, and kids who are physically active tend to perform better in school, including getting better grades. The benefits of activity are universal, including for children with disabilities or different abilities. Participation in sports and activities can promote overall wellness and help kids with disabilities maintain a healthy weight, which is a common problem. Participation, especially in team sports, can also promote a sense of belonging. On the Mayo Clinic Q&A podcast, Ask the Mayo Mom host Dr. Angela Mattke is joined by Dr. Amy Rabatin, a pediatric physical medicine and rehabilitation physician at Mayo Clinic Children’s Center, to discuss why physical activity is important for children of all abilities. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

If you're fully vaccinated for COVID-19 you can travel domestically and where travel is allowed internationally, according to new interim travel guidelines from the Centers for Disease Control and Prevention (CDC). Even with those recommendations the CDC continues to recommend not traveling unless it is essential. Regardless, the CDC strongly recommends people continue to wear a face mask, practice social distancing and sanitize their hands. Meanwhile, COVID-19 vaccine research is continuing in teenagers. "The early data show equal safety in young people age 12 to 16," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "I think this is going to imply that, somewhere between this fall and Christmas, we're going to be able to offer the (COVID-19) vaccine to every age group." In this Mayo Clinic Q&A podcast, Dr. Poland answers a number of listener questions, including how long the COVID-19 vaccines are predicted to last and if the current transmission research still supports wiping down household items. Dr. Poland also explains why someone who has had COVID-19 should still get a COVID-19 vaccine.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Esophageal cancer occurs in the esophagus — a long, hollow tube that runs from the throat to the stomach — and can occur anywhere along the esophagus. Men are more likely to develop esophageal cancer than women. While treatable, esophageal cancer is rarely curable. "It's an uncommon cancer," says Dr. Shanda Blackmon, a Mayo Clinic general thoracic surgeon. "But it's one of the deadliest cancers we know." Dr. Blackmon says survival rates are improving, but many people don't realize they have esophageal cancer until it's in the advanced stages. In this Mayo Clinic Q&A podcast, Dr. Blackmon discusses the risks, causes, symptoms and advances in treatments for esophageal cancer. She also explains what patients can expect with a diagnostic endoscopy and describes a new technique at Mayo Clinic that involves dropping a sponge down the patient's esophagus. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Across much of the U.S., people age 16 and over are now eligible to be vaccinated for COVID-19. But what about younger children? Children under 16 are not yet eligible to receive any of the COVID-19 vaccines that have been approved for emergency use in adults, and public health experts explain that children will need to be vaccinated for COVID-19 to reach herd immunity and stop the spread of the virus. Clinical trials in adolescents and young children are underway on Pfizer and Moderna COVID-19 vaccines. This week, Pfizer reported promising early results. Johnson & Johnson also is exploring conducting clinical trials with children. This all begs the question: When will those under 16 be able to be vaccinated for COVID-19? This edition of the Mayo Clinic Q&A podcast features an #AskMayoMom episode hosted by Dr. Angela Mattke, a pediatrician at Mayo Clinic Children's Center. Joining Dr. Mattke to discuss COVID-19, vaccines and children are Dr. Nipunie Rajapakse, a pediatric infectious diseases physician, and Dr. Emily Levy, a pediatric critical care and infectious diseases expert — both from Mayo Clinic. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

2020 was a record year for solid organ transplants, according to the Mayo Clinic Transplant Center. Despite the COVID-19 pandemic the center performed the most solid organ transplants across its three campuses in Arizona, Florida and Minnesota, than any time in history." All donors are tested for COVID-19," says Dr. David Douglas, chair of the Mayo Clinic Transplant Center. "Anyone who had active COVID-19 would not be used as a donor. In fact, it's important to make that point because there have been no recorded cases of COVID being transmitted from the donor to a recipient from transplantation." In this Mayo Clinic Q&A podcast, Dr. Douglas explains how the increase of telemedicine during the COVID-19 pandemic has changed care before and after transplants, and he addresses misconceptions about organ donation. He also talks about technologies in transplantation that are on the horizon. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

COVID-19 vaccine eligibility is increasing across the U.S., as many states lower age requirements for those who can be vaccinated for COVID-19. By the end of March, the U.S. will have received 240 million doses of COVID-19 vaccine, and 173 million doses of those will have been distributed, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Our way out of this (COVID-19 pandemic) is getting a vaccine," says Dr. Poland. "But when there's misinformation and disinformation circulating about the vaccines, it scares people." Dr. Poland emphasizes the importance of relying on credible, reliable medical resources for accurate information. He also has a message for young people, who think they are too healthy to get sick with COVID-19 and that they don't need a vaccine. "Even if you don't get seriously ill, that doesn't mean you won't have long-term complications," says Dr. Poland. "It also doesn't mean that you couldn't spread it to a member of your family or somebody else." In this week's Mayo Clinic Q&A podcast, Dr. Poland talks about the chances the U.S. will reach herd immunity. Also, he addresses the rollout and confusion around the Astra Zeneca's COVID-19 vaccine, and discusses the COVID-19 hot spots in South America. Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

"Mayo Clinic stands united in strong commitment toward anti-racism and rejecting all discrimination," says Dr. Anjali Bhagra, medical director for Mayo Clinic's Office of Equity, Diversity and Inclusion. "Our vision is to create a global environment of empowered belonging for everyone. This vision of belonging is a welcoming culture where all voices and perspectives are encouraged, acknowledged, celebrated and valued." In this Mayo Clinic Q&A podcast, Dr. Bhagra talks about Mayo partnering with the World Economic Forum, and she describes what she calls an ecosystem of change that includes health care professionals, social scientists, life scientists and political scientists. Dr. Bhagra also defines the words "equity," "inclusion" and "diversity," and she explains what "social determinants of health" means. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

A liver transplant is a surgical procedure that removes a liver that no longer functions properly and replaces it with a healthy liver from a deceased donor or a portion of a healthy liver from a living donor. The process for liver transplant in children is similar to the process for adults. But because children with liver disease face unique challenges, it is important to have transplant surgeons with extensive experience in pediatric and adult liver transplantation. This edition of the Mayo Clinic Q&A podcast covers liver disease and liver transplant in children. Guests on the podcast are three Mayo Clinic transplant experts: Dr. Timucin Taner, a Mayo Clinic transplant surgeon, and Dr. Sara Hassan and Dr. Samar Ibrahim— both Mayo Clinic pediatric hepatologists. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The COVID-19 virus mutates and replicates when people let down their guard and don't follow safety protocols, such as practicing social distancing and wearing a mask. "I think most of us expect a major surge because of spring break travel and the relaxation of restrictions," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And the sort of COVID fatigue that all of us feel, in one way or another." In this Mayo Clinic Q&A podcast, Dr. Poland addresses the potential of a fourth COVID-19 surge, new information regarding the COVID-19 vaccines for pregnant women and he discusses research for next generation vaccines for COVID-19 variants.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Children and adults with congenital heart disease need complex, multifaceted care for continued survival and quality of life. "These heart defects may be silent when a child is born and might only surface as the person gets older," says Dr. David Majdalany, a Mayo Clinic cardiologist. Dr. Majdalany adds that many patients who were born with a congenital heart disease undergo an intervention of some kind and they think things are fixed. "They think they have no further need for cardiac surveillance, so they fall off the radar of getting followed because they feel so good," says Dr. Majdalany. In this Mayo Clinic Q&A podcast, Dr. Majdalany addresses the issue of pregnancy for women who have congenital heart disease. He also details the intricacies and seriousness of congenital heart disease, emphasizing the need for good transitioning from pediatric care to adult cardiovascular care. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The COVID-19 virus spreads through respiratory droplets. This means treating patients who have diseases or injuries involving the ears, nose or throat, or the head and neck, requires particular precautions. "COVID-19 taught us all to be more nimble," says Dr. Devyani Lal, a Mayo Clinic otolaryngologist and head and neck surgeon. She says the COVID-19 pandemic required Mayo Clinic's Department of Otolaryngology to pivot quickly and require that patients be tested for COVID-19 before appointments. In this Mayo Clinic Q&A podcast, Dr. Lal explains more about COVID-19 safety measures that have been implemented and encourages not to delay treatment. She also details how extensive the otolaryngology practice is at Mayo Clinic. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Millions of people in the U.S. are being vaccinated for COVID-19. However, discussion is ongoing as to whether people who are immunocompromised, such as patients undergoing cancer treatment, or people who have autoimmune diseases, should be vaccinated for COVID-19. "Both of those categories (of people) should be vaccinated," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Those are not contraindications. Those are indications to get the vaccine." He adds that research is ongoing, but current information demonstrates the benefits far outweigh the theoretical risks. In this Mayo Clinic Q&A podcast, Dr. Poland talks about vaccine hesitancy, and patients who are immunocompromised or have autoimmune conditions. Also, he discusses next steps in the journey to vaccinate children for COVID-19. And he reviews recent guidance from the Centers for Disease Control and Prevention Control about in-person gatherings.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Inflammatory bowel disease is common, and it is becoming more common in many populations. Dr. William Faubion Jr., a Mayo Clinic gastroenterologist, says inflammatory bowel disease is an umbrella term that covers Crohn's disease and ulcerative colitis, and that inflammatory bowel disease is an emerging public health problem. "The most recent estimates would be that, depending on where you live and what region in the world you live, as many as 1 in 250, to 1 in 300 people may be affected with inflammatory bowel disease," says Dr. Faubion. Dr. Faubion points out that inflammatory bowel disease is a combination of a complex genetic disease and an immunologic disease, as well as environmental variants or triggers. In this Mayo Clinic Q&A podcast, Dr. Faubion explains that inflammatory bowel disease is very different from irritable bowel syndrome. He also describes symptoms, tests and treatments for inflammatory bowel disease, including how researchers are using artificial intelligence to determine the right medication for each patient. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Your kidneys remove waste from your blood and regulate a healthy balance between water, sodium and minerals in your bloodstream. "Kidneys filter intoxicants, drugs and waste products out of your blood," says Dr. Scott Cheney, a Mayo Clinic urologic surgeon. "We would actually die within about a week without having good kidney function." Poor kidney function could mean kidney cancer, but signs or symptoms are rare in its early stages. Patient are sometimes informed about kidney cancer tumors when they are discovered during CT scans or other imaging techniques for unrelated ailments. In this Mayo Clinic Q&A podcast, Dr. Cheney discusses different types of kidney cancers, how smoking can affect the kidneys and why treatment usually involves surgery. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Being a new parent is a time filled with excitement, exhaustion, and questions as children grow and develop rapidly during the first few years of life. Typical concerns for parents with infants and toddlers include eating, sleeping, common illnesses, immunizations and safety. On the Mayo Clinic Q&A podcast, a special edition of "Ask the Mayo Mom" focuses on parenting questions during the first few years of life. Dr. Angela Mattke a Mayo Clinic pediatrician and host of "Ask the Mayo Mom" is joined by Dr. Kelsey Klaas, a pediatrician at Mayo Clinic Children’s Center. Dr. Klass is the co-medical editor of the updated 2nd edition of Mayo Clinic's Guide to Your Baby's First Years. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The COVID-19 pandemic has revealed how quickly life can change. That's evident in people's personal lives and across the scientific community. Remarkable advances have been made in science over the past year, guided by international research collaborations. "When you look at nine months from when we first identified this pathogen to having a vaccine, that's as close to a human miracle, if I could use that term, as as one could expect," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. But he says there have been some frustrations. "As soon as we make some progress, everybody wants to open up and relax restrictions," says Dr. Poland. "Opening up and getting back to normal is not a light switch." In this Mayo Clinic Q&A podcast, Dr. Poland talks about lessons learned during the COVID-19 pandemic, and that vaccinations aren't enough to beat the COVID-19 virus and variants. He also says that communicating science and public health messaging needs to improve in the future.Research disclosures for Dr. Gregory Poland. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy