Stem cell therapy - Dr. Deepak Vangala (english) * Hämatoonkologie
An introduction to stem cell transplantation, their indications, side effects and CAR-T therapy
Klinisch Relevant Podcast · Die Fortbildungsplattform für Ärzte und medizinisches Fachpersonal
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Show Notes
In this Klinisch Relevant podcast episode in English, moderator Laura Reynolds speaks with Dr. med. Deepak Vangala, a practicing consultant in internal medicine and haematology/medical oncology in Germany.
In this engaging conversation, Deepak talks about stem cell transplants, explaining the difference between autologous and allogeneic, their indications, potential side effects and the patient journey. He also discusses CAR-T therapy, an exciting therapy in this field. He also touches on psychological aspects for patients as well as the team looking after them. Deepak has a great ability to explain these concepts in a simple yet engaging way and will definitely leave you with a deeper understanding of this topic!
If you are interested in reading more on this topic, here are some sources of further reading (German language). Stem Cell Therapy:
Allogene Stammzelltransplantation [Deutsche Gesellschaft für Haematologie und medizinische Onkologie, Östereichische Gesellschaft für Haematologie und medizinische Onkologie, Schweizerische Gesellschaft für Haematologie, Schweizerische Gesellschaft für medizinische Onkologie]
CAR-T Therapy:
CAR-T Zellen: Management von Nebenwirkungen — Onkopedia June 2020 o https://www.onkopedia.com/de/onkopedia/guidelines/car-t-zellen-management-von-nebenwirkungen/@@guideline/html/index.html o Deutsche Gesellschaft für Haematologie und medizinische Onkologie, Östereichische Gesellschaft für Haematologie und medizinische Onkologie, Schweizerische Gesellschaft für Haematologie, Schweizerische Gesellschaft für medizinische Onkologie o Gives a good overview of the MOA of the potential side effects of CAR-T therapy and its management. Has nice graphics and treatment flowcharts.
CAR-T-Zell-Therapie: Aussichten und Risiken (aerzteblatt.de) 2018
Dtsch Arztebl 2018; 115(7): [38]; DOI: 10.3238/PersOnko.2018.02.16.07, Buchholz, Christian J.; Hartmann, Jessica; Schüßler-Lenz, Martina; Keller-Stanislawski, Brigitte
- CAR-T-Zelltherapie – neue Behandlungsmöglichkeiten der Immunonkologie (journalonko.de) March 2021
Nice for an introduction to this theme.
CAR-T-Zell-Therapie: Antworten auf wichtige Fragen | DKG (krebsgesellschaft.de) o Nice for an introduction to this theme. Goes through in a Q and A format and also videos. o https://www.krebsgesellschaft.de/onko-internetportal/basis-informationen-krebs/krebsarten/non-hodgkin-lymphome/car-t-zell-therapie-wichtige-fragen-antworten.html#:~:text=Die%20CAR%2DT%2DZell%2D,Hodgkin%2DLymphome%20(NHL).