What's Different Between One Colorectal Cancer and Another? It's All in the Genes
Journal of Clinical Oncology (JCO) Podcast · Journals Online Team
March 5, 201215m 9s
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Show Notes
This podcast will discuss the current role of characterizing KRAS and BRAF in the management of colorectal cancer as well as a manuscript by Popovici and colleagues entitled "Identification of a poor prognosis BRAF-mutant-like population of colon cancer patients". In this manuscript, a molecular signature that characterizes a subgroup of colorectal cancers that behave like BRAF mutant tumors but do not have true BRAF mutations. The research moves beyond analysis of a single gene to characterize a tumor's phenotype.