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Second Tumors in PTEN Mutation-Positive Patients: Are They Recurrences or New Primaries?

Second Tumors in PTEN Mutation-Positive Patients: Are They Recurrences or New Primaries?

Journal of Clinical Oncology (JCO) Podcast · Journals Online Team

April 28, 20147m 43s

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Show Notes

Among more than 2,000 patients with an invasive cancer, more than 5% had a mutation in PTEN and almost half of these patients had a second malignancy. This observation has implications for patients with breast, endometrial and thyroid cancer, and those with known PTEN mutations.