Beyond the Plasma Cell: Proteasome Inhibition in Acute Myelogenous Leukemia
Journal of Clinical Oncology (JCO) Podcast · Journals Online Team
November 2, 20129m 27s
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Show Notes
In this podcast, Attar and colleagues explore whether patients aged 60-75 who enter remission with bortezomib added to standard anthracycline plus cytarabine chemotherapy during induction can be safely treated with intermediate dose cytarabine along with dose escalating bortezomib during consolidation. This regimen was tolerated at the highest dose of bortezomib tested, 1.3 mg/m2, and further randomized studies of this regimen will be planned.