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Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)

Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)

JAMA Author Interviews · American Medical Association

November 18, 202414m 21s

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Show Notes

Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic's Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran produced more than 80% reductions in time-averaged lipoprotein(a) concentration. Related Content: