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Revisiting the SUMMIT Trial | JACC Deep Dive

Revisiting the SUMMIT Trial | JACC Deep Dive

JACC This Week · American College of Cardiology

May 6, 20255m 55s

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Show Notes

This JACC Deep Dive in our May 13 issue highlights new findings from the SUMMIT CKD study, showing that terzepatide improves symptoms, function, and weight in patients with HFpEF and obesity—regardless of kidney function. The analysis also underscores the importance of using both creatinine and cystatin C to better assess kidney health. Reviewers praised the study's methodological rigor and dual focus, while noting the need for larger, long-term trials to confirm renal outcomes.