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Non-Modifiable Risk Factors Predict Outcomes in Brugada Syndrome

Non-Modifiable Risk Factors Predict Outcomes in Brugada Syndrome

JACC This Week · American College of Cardiology

November 11, 20249m 42s

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Show Notes

In this episode, Dr. Valentin Fuster discusses a groundbreaking study on Brugada Syndrome, exploring how non-modifiable risk factors—such as male sex, SCN 5A mutations, and polygenic risk scores—can predict life-threatening arrhythmic events in patients. The research, published in JACC (November 2024), offers new insights into personalized risk assessment for this inherited arrhythmia syndrome, though its clinical implications remain limited for now.