Integrative Lyme Solutions with Dr. Karlfeldt

Still struggling with fatigue, brain fog, and anxiety even after Lyme treatment? This is a special re-release of an important episode originally recorded in 2025 that we felt needed to be brought back. More patients than ever are dealing with stalled healing journeys, and one of the most overlooked reasons is mold toxicity. In this episode of Integrative Lyme Solutions, Dr. Michael Karlfeldt breaks down how mold and mycotoxins can silently sabotage Lyme recovery by suppressing the immune system, inflaming the brain, and mimicking symptoms often blamed on chronic infections. You will learn the difference between mold exposure and colonization, how mold affects the nervous system and mental health, why it must often be addressed before Lyme protocols can fully work, and the most effective detox and recovery strategies available. If you feel like you are doing everything right but still not improving, this conversation may help uncover the missing piece. Key Takeaways: 0:00 Introduction 3:00 Mold exposure vs colonization explained 8:30 Why mold symptoms look like Lyme 11:30 How mold suppresses the immune system 16:45 Mold detox: environment, binders, and antifungals 28:00 Mold, anxiety, and brain inflammation 30:30 Limbic retraining and nervous system healing Resources Mentioned: Toxic: Heal Your Body - https://a.co/d/0ajEwCyy Break the Mold - https://a.co/d/03CqJLLS Great Plains Laboratory (now Mosaic Diagnostics) - https://mosaicdx.com/ Vibrant America - https://vibrant-wellness.com/ Surviving Mold VCS Test - https://www.survivingmold.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Why do so many Lyme patients test negative while feeling anything but healthy? This is a special re-release of a powerful episode originally recorded in 2025. We felt it was too important not to bring back, especially as more people continue to struggle with confusing lab results and unanswered symptoms. The insights shared here are just as relevant today, if not more, and deserve to be heard again. In this episode of Integrative Lyme Solutions, Dr. Michael Karlfeldt breaks down the confusing world of Lyme disease testing and reveals why conventional lab results often fail chronic illness patients. Drawing insights from leading experts like Dr. Bruce Patterson and Dr. Joseph Burrascano, this episode uncovers the limitations of ELISA, Western Blot, and PCR testing and why they were never designed for complex, chronic cases. You will learn how Lyme evades detection, why immune dysfunction leads to false negatives, and how advanced testing methods like cytokine panels, T-cell testing, and FISH are reshaping diagnosis. If you have ever been told your labs are normal while your body says otherwise, this episode will change how you understand your health and your next steps forward. Key Takeaways: 0:00 Introduction 2:05 ELISA and Western Blot were never built for chronic Lyme 6:10 Immune dysfunction leads to false negatives 10:30 PCR testing limitations and missed infections 12:00 Expanding beyond standard labs into specialty testing 17:00 FISH testing detecting live organisms in the blood 22:00 Why combining tests gives a clearer diagnosis 23:30 Immune system testing the future of Lyme detection 28:00 Symptom patterns reveal different infections 30:15 Choosing the right test based on your stage 32:00 When to stop testing and start healing Resources Mentioned: ArminLabs https://arminlabs.com/ IGeneX https://igenex.com/ Galaxy Diagnostics https://www.galaxydx.com/ DNA Connexions https://dnaconnexions.com/ IncellDX https://incelldx.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What happens when Lyme disease is repeatedly dismissed even when the symptoms are clear? In this episode of Integrative Lyme Solutions, Dr. K speaks with Lyme advocate Amy Rose, who spent more than eight years searching for answers after being infected by a tick bite in 2008. Within days she developed severe flu-like symptoms and later discovered a large bullseye rash on her shoulder. Despite these classic warning signs, doctors repeatedly told her Lyme disease was impossible because she had been bitten in Arkansas. Multiple tests came back negative and she was given numerous misdiagnoses and medications instead of answers. Amy shares how her health continued to decline while she saw 27 doctors before finally receiving a proper diagnosis from a Lyme-literate practitioner. She also explains how this experience led her to start the Arkansas Lyme Foundation to support patients in a state where Lyme disease is still widely denied. Her story reveals the serious gaps in Lyme testing, the consequences of misdiagnosis, and the power of patient advocacy. Key Takeaways: 0:00 Introduction 2:15 Amy Rose’s Lyme infection and early symptoms in 2008 6:40 The bullseye rash and why Lyme was still missed 10:30 Five negative tests through Labcorp and misdiagnosis 16:50 Neurological Lyme and being misdiagnosed with Alzheimer’s 22:10 Losing the ability to drive due to brain inflammation 26:30 Finding a Lyme-literate doctor after seeing 27 physicians 32:45 Starting the Arkansas Lyme Foundation 38:20 Why Arkansas still denies Lyme disease exists 44:15 Reaching remission and focusing on cellular health and mold detox Resources Mentioned: Arkansas Lyme Foundation - https://www.arkansaslyme.org/ Labcorp - https://www.labcorp.com/ Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What if Alzheimer’s, multiple sclerosis, chronic fatigue, and even psychiatric symptoms are not random but driven by hidden infections? In this episode of Integrative Lyme Solutions, Dr. K sits down with research scientist and Lyme survivor Nikki Schultek to explore the infection hypothesis behind chronic disease. After battling years of misdiagnosed symptoms including asthma flares, interstitial cystitis, arrhythmias, neurological decline, and suspected MS, Nikki uncovered a complex web of infections including Borrelia, Bartonella, Babesia, Chlamydia pneumoniae, Epstein-Barr virus, and more. Now founder of the Alzheimer’s Pathobiome Initiative, Nikki is leading a global consortium investigating how stealth pathogens may trigger neurodegeneration, immune dysfunction, and dementia. This conversation dives into intracellular infections, the Herxheimer reaction, amyloid as an antimicrobial response, sterile brain autopsies, precision medicine, and why federal health agencies are finally acknowledging Lyme disease as a serious public health crisis. If you or someone you love is dealing with chronic Lyme, long COVID, autoimmune illness, or cognitive decline, this episode may change how you see disease. Key Takeaways: 0:00 Introduction 3:15 Asthma, air hunger, and early misdiagnoses 8:40 From interstitial cystitis to suspected multiple sclerosis 14:30 Discovering intracellular infections and Chlamydia pneumoniae 18:45 Lyme, Bartonella, Babesia and the whack-a-mole effect 24:10 The Pathobiome concept and microbial imbalance 27:30 Alzheimer’s disease and the infection hypothesis 32:00 Sterile brain autopsies and spinal fluid research 35:20 Amyloid plaque as an antimicrobial defense mechanism 41:00 APOE4, genetics, and infection susceptibility 44:30 Federal recognition of Lyme disease and future funding Resources Mentioned: Alzheimer’s Pathobiome Initiative - https://alzheimerspathobiome.org ILADS - https://www.ilads.org ILADS Education Foundation - https://www.iladef.org Philadelphia College of Osteopathic Medicine - https://www.pcom.edu Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What happens when Lyme disease goes undiagnosed for 15 years — and the emotional toll becomes just as devastating as the physical symptoms?In this episode of Integrative Lyme Solutions, Dr. K sits down with Susan Pogorzelski, author of The Last Letter: A Novel and founder of the Lyme Brave Foundation. Susan shares her 30-year journey through misdiagnosis, neurological decline, co-infections like Babesia, severe fatigue, psychiatric symptoms, and the long road of recovery. From being dismissed by doctors to experiencing suicidal ideation during treatment, Susan opens up about the isolation, trauma, and resilience that shaped her healing.This powerful conversation explores Lyme misdiagnosis, Babesia treatment, herxing, emotional trauma, nervous system regulation, EFT tapping, relapse recovery, and how chronic illness can reshape identity. If you or a loved one is navigating chronic Lyme disease, co-infections, or the emotional weight of invisible illness, this episode is both validation and hope.Key Takeaways:0:00 Introduction3:15 15 years of misdiagnosis and declining neurological health8:20 Gallbladder surgery, rapid deterioration, and ER visits12:05 Lyme diagnosis and multiple co-infections confirmed15:40 Babesia treatment and what moved the needle in recovery19:30 Herx reactions, suicidal ideation, and psychological symptoms23:50 Emotional trauma, loneliness, and invisible illness27:45 EFT tapping, nervous system healing, and energetic tools30:10 Relapses, flares, and building resilience over time33:00 Lyme Brave Foundation and supporting patients emotionallyResources Mentioned:Susan Pogorzelski Website - https://www.susanpogorzelski.com/aboutLyme Brave Foundation - https://lymebravefoundation.orgThe Last Letter: A Novel by Susan Pogorzelski - https://www.amazon.com/Last-Letter-Novel-Susan-Pogorzelski/dp/0988875136Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.#Babesia #InvisibleIllness #ChronicLyme _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Is chronic babesiosis finally getting the scientific attention it deserves?In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Geoff Dow, CEO & President of Sixty Degrees Pharmaceuticals, to discuss a groundbreaking clinical trial targeting chronic babesiosis — a common and often overlooked Lyme co-infection. Originally developed for malaria prevention, the drug Tafenoquine (brand name Kodatef®) is now being studied for its potential to treat persistent Babesia infections and Lyme-related fatigue.They explore the science behind red blood cell parasites, how Babesia differs from malaria, why chronic babesiosis remains controversial, and what makes this new trial the first FDA-reviewed IND study focused on chronic disease. If you or a loved one struggle with Lyme-related fatigue, relapsing babesiosis, or limited treatment options, this conversation offers cautious optimism and a closer look at the future of targeted therapies.Key Takeaways:0:00 Introduction3:10 From Malaria Drug Development to Lyme Co-Infections6:45 How Babesia Infects Red Blood Cells and Causes Fatigue10:40 Why Chronic Babesiosis Is Still Controversial14:50 No FDA-Approved Drugs Specifically for Babesiosis18:30 New Clinical Trials for Chronic and Relapsing Babesiosis24:00 Measuring Fatigue as a Primary Endpoint in Chronic DiseaseResources Mentioned:Sixty Degrees Pharmaceuticals - https://www.sixtydegreespharma.comKodatef® (Tafenoquine) Information - Available via company website aboveMount Sinai (Clinical Trial Site) - https://www.mountsinai.orgYale Babesiosis Case Series (Referenced Study) - https://medicine.yale.eduMedical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Can Lyme disease begin before birth — and could it be driving neurodevelopmental conditions like autism, ADHD, and anxiety?In this episode of Integrative Lyme Solutions, Dr. K is joined by Dr. Somer DelSignore, a leading pediatric integrative clinician, to explore the overlooked science of congenital Lyme and in utero transmission of vector-borne infections. Dr. DelSignore explains how infections such as Borrelia, Bartonella, and Babesia can cross the placenta, disrupt fetal brain development, and silently fuel inflammation that shows up later as behavioral, cognitive, and immune dysfunction.You’ll learn why standard TORCH testing fails to catch these infections, what symptoms parents should watch for in infants and children, and how addressing inflammation, infections, and immune imbalance can dramatically improve outcomes. This episode offers critical insight for parents, practitioners, and anyone focused on true prevention and root-cause healing in pediatric Lyme disease.Key Takeaways:0:00 Introduction and Dr. Somer DelSignore’s clinical journey3:10 From pediatric ICU to integrative Lyme care6:20 Congenital Lyme: 40 years of overlooked science9:00 Why TORCH testing misses vector-borne infections12:45 Preconception testing and prevention strategies15:30 Why treating Lyme before pregnancy matters18:05 Infant symptoms parents should never ignore21:10 Autism, neuroinflammation, and misdiagnosis24:15 The RESET framework for pediatric healing28:10 What real recovery can look like for childrenResources Mentioned:IGeneX Laboratories – https://igenex.comTLABDX (Babesia & Bartonella testing) – https://www.tlabdx.com/Horowitz/MSIDS 38 point symptom checklist – https://projectlyme.org/msids-questionnaire/IV Ozone Therapy – https://health.clevelandclinic.org/ozone-therapySOT (Supportive Oligonucleotide Therapy) – https://projectlyme.org/supportive-oligonucleotide-therapy-sot-for-lyme/Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Why do so many Lyme patients stay sick — even after treating infections, detoxing, and “doing everything right”?In this episode of Integrative Lyme Solutions, Dr. K sits down with functional and environmental medicine pioneer Dr. Kelly McCann to explore why Lyme disease, mold toxicity, and Mast Cell Activation Syndrome (MCAS) are rarely just infections — and why true healing requires addressing the terrain of the body, nervous system, emotions, and spirit. Drawing from her own journey through mold illness and Lyme disease, Dr. McCann explains how immune dysregulation, trauma, limbic system activation, and cell membrane damage keep patients stuck in chronic illness.This conversation dives deep into mast cell activation, mold exposure, Bartonella, phosphatidylcholine therapy, biofilms, nervous system regulation, emotional trauma, spirituality, and why symptoms are not betrayals — but messages. If you’ve been gaslit, dismissed, or feel like your body is working against you, this episode offers validation, insight, and a radically different way to understand Lyme healing.Key Takeaways:0:00 Introduction and Dr. Kelly McCann’s personal healing journey3:00 Mold exposure as a hidden driver of chronic illness6:20 Lyme, Bartonella, and the overlap with mast cell activation9:30 Why siloed medicine fails complex chronic disease patients11:40 Phosphatidylcholine and cell membrane repair explained13:50 When antimicrobial treatment stalls, look beyond infections16:50 Mast cell activation, trauma, and nervous system dysregulation18:40 The limbic system’s role in chronic illness21:10 Emotional trauma, immune boundaries, and people-pleasing24:00 Language, identity, and separating yourself from disease26:10 Terrain theory and why healing requires self-honoring choices29:00 Illness as an invitation, not a punishmentResources Mentioned:Dr. Kelly McCann – https://drkellymccann.comThe Spring Center – https://thespringcenter.comThe Unforgetting Project – https://unforgettingproject.comMicroGen DX (Next Generation Sequencing) – https://microgendx.comByron White Formulas – https://byronwhiteformulas.com _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

What happens when your body is shutting down—but every scan, lab, and specialist says they “can’t find anything”? In this episode, we unpack the reality of Lyme-related neurological illness, the emotional toll of chronic disease, and what it takes to keep moving forward when healing isn’t linear.We’re joined by Dr. Kristi Hellenbrand, DC, chiropractor and author of Let Me Tell You a Secret…She Makes It: a Lyme survival story, who shares how a tick bite in 2020 leads to rapid neurological decline, wheelchair-level symptoms, and relentless migraines—until a clinician treats based on a clinical diagnosis and response to treatment, not just lab confirmation. Kristi walks us through the decision points that change everything: antibiotics as an early signal, later testing that reveals a viral layer, and a pivotal turn to the Horowitz protocol (including double-dose dapsone) as part of her path back to remission.Key Takeaways:03:45 Lyme can first appear as heart and neurological symptoms—not joint pain.07:15 Clinical diagnosis can move treatment forward when labs and specialists stall.10:30 Response to treatment can confirm infection before tests do.13:10 Healing from Lyme is nonlinear and follows the grief cycle.14:25 The Horowitz protocol helped resolve daily, debilitating migraines.19:15 Retracing symptoms signal healing in reverse order—not relapse.31:00 Fear is inflammatory; regulating the nervous system supports long-term recovery.Resources Mentioned:Let Me Tell You a Secret...She Makes It.: - a Lyme survival story - https://www.amazon.com/Let-Tell-You-Secret-Makes/dp/B0CJB825R1Lyme Lives Here - https://www.lymeliveshere.com/#lymewarrior #chronicillness #TheKarlfeldtCenter #IntegrativeLymeSolutionsWant to guest on our shows?Calendly Link for Integrative Lyme Solutions: https://calendly.com/drmichaelk/integrative-lyme-solutions-podcast-interviewCalendly Link for Integrative Cancer Solutions: https://calendly.com/drmichaelk/podcast-interviewCalendly Link for Dr. K Show: https://calendly.com/drmichaelk/dr-k-show-interviewBreaking Free From Lyme: A Comprehensive Guide to Healing and Recovery-URL: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lyme-Price: $24.99-Discount Code: LYMEPODCASTUnleashing 10X Power: A Revolutionary Approach to Conquering Cancer-URL: https://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancer-URL: https://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-Discount Code: CANCERPODCAST2The Science and Spirit of Transformation: A Holistic Guide to Elevating Health, Consciousness, and Purpose-URL: https://store.thekarlfeldtcenter.com/products/the-science-and-spirit-of-transformation-Price: $24.99-Discount Code: DRKSHOWPODCAST _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email [email protected] out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!