Season 2 · Episode 4
ID4U Episode 14 Cholera
ID4U - Infectious Disease Podcasts for Users of the CMES program · Jessica Pelletier
May 28, 202516m 37s
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Show Notes
Dr. Jessica Pelletier and Dr. Kamoga Dickson discuss the epidemiology, pathophysiology, clinical presentation, diagnostic workup, management, and prevention of cholera.
Take-Home Points:
- Cholera is a disease with high morbidity that disproportionately affects sub-Saharan Africa
- The O1 and O139 serogroups of V. cholera make cholera toxin and cause the disease
- Colonization happens in the small intestine, so higher volumes of bacteria that make it to the small intestine are more likely to cause disease
- The classic presentation involves rice water stools and dehydration, but vomiting is also possible
- Patients with mild to moderate dehydration should receive oral rehydration, and those with severe dehydration should receive balanced IV fluids (where available)
- Severe cases need antibiotics based on local guidelines
- Prevention involves sanitation measures and vaccination
You can view the full show notes and references here: https://docs.google.com/document/d/1HCMld8vCdiPMRSAdSeWu2VWZFBhEF15Nvrsa_ov9YuA/edit?usp=sharing
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