Episode 002: LDL Under 55 Wins Big, Medicare Covers GLP-1, and Second Weekly Insulin Emerges -- The Week in Diabetes & Endocrinology (April 10, 2026)
April 9, 202616m 45s
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Show Notes
The Week in Diabetes & Endocrinology — Episode 002 | April 10, 2026
From Hormone Insight (hormoneinsight.com)
Six stories this week that endocrinologists, diabetologists, and internists need to know.
TIMESTAMPS:
0:00 — Introduction & This Week's Stories
1:30 — EZ-PAVE: LDL Under 55 Beats Under 70 in ASCVD (NEJM)
7:00 — CMS BALANCE Model: Medicare Covers GLP-1 for Obesity
11:00 — GZR4: Second Once-Weekly Insulin Beats Glargine AND Degludec
14:00 — CagriSema NMA at ACC 2026: Best Efficacy AND Tolerability
16:30 — BP Variability Predicts Dementia in Type 2 Diabetes (ADVANCE)
19:00 — Blood-Flow Restriction Training Boosts Mitochondria in T2D
21:00 — Closing Thoughts
REFERENCES & SHOW NOTES:
▸ EZ-PAVE (NEJM): https://doi.org/10.1056/NEJMoa2600283
▸ CMS BALANCE Model: https://www.cms.gov/priorities/innovation/innovation-models/balance
▸ GZR4 SUPER trials: https://www.prnewswire.com/news-releases/gan--lee-pharmaceuticals-once-weekly-basal-insulin-gzr4-injection-meets-primary-endpoints-in-two-pivotal-phase-3-clinical-trials-super-1-and-super-2-302730104.html
▸ CagriSema NMA (DOM): https://doi.org/10.1111/dom.70667
▸ ADVANCE BP variability (JAHA): https://doi.org/10.1161/JAHA.125.044061
▸ BFRT in T2D (Cell Metab): https://doi.org/10.1016/j.cmet.2025.12.016
ABOUT THIS PODCAST:
A weekly evidence-based review of the top stories in diabetes, obesity, thyroid, and endocrinology — modeled on Medscape's "This Week in Cardiology." New episodes every Thursday. For healthcare professionals.
▸ Website: https://hormoneinsight.com
▸ Full show notes: https://hormoneinsight.com/podcast
DOWNLOAD THE APP:
▸ iOS: https://apps.apple.com/dz/app/hormone-insight/id6749515856
▸ Android: https://play.google.com/store/apps/details?id=com.fahadwali78.hormoneinsightmobile&hl
️ This content is intended for healthcare professionals. It does not constitute medical advice for patients.
#Endocrinology #DiabetesResearch #LDLcholesterol #EZPAVE #GLP1 #Medicare #CagriSema #WeeklyInsulin #GZR4 #BloodPressure #Dementia #BFRT #ObesityMedicine #MedicalPodcast #HormoneInsight #CME #MedTwitter #DoctorsOfYouTube #EvidenceBasedMedicine #Tirzepatide #Semaglutide
From Hormone Insight (hormoneinsight.com)
Six stories this week that endocrinologists, diabetologists, and internists need to know.
TIMESTAMPS:
0:00 — Introduction & This Week's Stories
1:30 — EZ-PAVE: LDL Under 55 Beats Under 70 in ASCVD (NEJM)
7:00 — CMS BALANCE Model: Medicare Covers GLP-1 for Obesity
11:00 — GZR4: Second Once-Weekly Insulin Beats Glargine AND Degludec
14:00 — CagriSema NMA at ACC 2026: Best Efficacy AND Tolerability
16:30 — BP Variability Predicts Dementia in Type 2 Diabetes (ADVANCE)
19:00 — Blood-Flow Restriction Training Boosts Mitochondria in T2D
21:00 — Closing Thoughts
REFERENCES & SHOW NOTES:
▸ EZ-PAVE (NEJM): https://doi.org/10.1056/NEJMoa2600283
▸ CMS BALANCE Model: https://www.cms.gov/priorities/innovation/innovation-models/balance
▸ GZR4 SUPER trials: https://www.prnewswire.com/news-releases/gan--lee-pharmaceuticals-once-weekly-basal-insulin-gzr4-injection-meets-primary-endpoints-in-two-pivotal-phase-3-clinical-trials-super-1-and-super-2-302730104.html
▸ CagriSema NMA (DOM): https://doi.org/10.1111/dom.70667
▸ ADVANCE BP variability (JAHA): https://doi.org/10.1161/JAHA.125.044061
▸ BFRT in T2D (Cell Metab): https://doi.org/10.1016/j.cmet.2025.12.016
ABOUT THIS PODCAST:
A weekly evidence-based review of the top stories in diabetes, obesity, thyroid, and endocrinology — modeled on Medscape's "This Week in Cardiology." New episodes every Thursday. For healthcare professionals.
▸ Website: https://hormoneinsight.com
▸ Full show notes: https://hormoneinsight.com/podcast
DOWNLOAD THE APP:
▸ iOS: https://apps.apple.com/dz/app/hormone-insight/id6749515856
▸ Android: https://play.google.com/store/apps/details?id=com.fahadwali78.hormoneinsightmobile&hl
️ This content is intended for healthcare professionals. It does not constitute medical advice for patients.
#Endocrinology #DiabetesResearch #LDLcholesterol #EZPAVE #GLP1 #Medicare #CagriSema #WeeklyInsulin #GZR4 #BloodPressure #Dementia #BFRT #ObesityMedicine #MedicalPodcast #HormoneInsight #CME #MedTwitter #DoctorsOfYouTube #EvidenceBasedMedicine #Tirzepatide #Semaglutide