Heart Podcast

In this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by cardiologist and EP specialist Dr John Mandrola from Louisville, Kentucky. John is also Medscape's chief cardiology correspondent. They discuss the eye-catching late-breaking trials from the upcoming ACC meeting in Orlando. Please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 John Mandrola's podcast at Medscape - https://www.medscape.com/index/list_10295_0 John Mandrola's columns at Medscape - https://www.medscape.com/index/section_10325_0 and https://www.medscape.com/index/section_10382_0

In this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by Dr Paul Sainsbury from Bradford Royal Infirmary. They discuss his recent Education in Heart paper all about refractory angina. Paul is an expert in this area and runs one of the few specialist services in the UK. Please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 Link to published paper: http://heart.bmj.com/content/103/23/1911 Link to the Bradford specialist clinic mentioned during the podcast: http://refractoryangina.uk/

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd visits Professor Darrel Francis and Dr. Rasha Al-Lamee at "Orbita HQ" in Imperial College, London to discuss their groundbreaking trial. This is the second part of a wide-ranging discussion during which they cover why the trial was desperately needed, the barriers to getting started and what the startling and unexpected results might mean for PCI in stable coronary artery disease. The concept of post-publication ‘trial by Twitter’ rounds out their chat. Link to published paper: Orbita trial : http://linkinghub.elsevier.com/retrieve/pii/S0140673617327149 and editorial mentioned during the discussion : https://www.pcronline.com/eurointervention/127th_issue/volume-13/number-12/217/swimming-against-the-tide-insights-from-the-orbita-trial.html

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd visits Professor Darrel Francis and Dr. Rasha Al-Lamee at "Orbita HQ" at Imperial College, London to discuss their groundbreaking trial. In a wide-ranging discussion they cover why the trial was desperately needed, the barriers to getting started and what the startling and unexpected results might mean for PCI in stable coronary artery disease. The second half of the podcast will be released in two weeks. Link to published paper: Orbita trial : http://linkinghub.elsevier.com/retrieve/pii/S0140673617327149 Editorial mentioned during the discussion : https://www.pcronline.com/eurointervention/127th_issue/volume-13/number-12/217/swimming-against-the-tide-insights-from-the-orbita-trial.html

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by cardiologist and cardiac CT expert Dr. Ed Nicol from The Royal Brompton Hospital, London. They discuss what the updated NICE guidelines for the assessment of stable chest pain mean for the UK imaging community. They also cover the differences between the UK, European and US guidelines and how technological developments in CT might help patients and save money. Please leave us a podcast review at itunes.apple.com/gb/podcast/heart…id445358212?mt=2 Link to published papers and podcasts: Podcasts on the NICE guidelines from authors for, and against, the new approach: https://soundcloud.com/bmjpodcasts/assessing-stable-chest-pain-a-nice-win-for-ct?in=bmjpodcasts/sets/heart-podcast https://soundcloud.com/bmjpodcasts/stable-chest-pain-assessment-revisited-the-case-against-cardiac-ct?in=bmjpodcasts/sets/heart-podcast Assessment of patients with stable chest pain : http://heart.bmj.com/content/early/2017/10/30/heartjnl-2017-311212 Challenges in delivering computed tomography coronary angiography as the first-line test for stable chest pain : http://heart.bmj.com/content/early/2017/11/14/heartjnl-2017-311846

In this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by Dr Atul Anand from the University of Edinburgh. They discuss his recent research paper about using cardiac myosin-binding protein C as a marker of progression of aortic stenosis. Link to published paper: http://heart.bmj.com/content/early/2017/12/01/heartjnl-2017-312257.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by a vascular biology legend, Professor Peter Libby from Harvard University and Chief of Cardiovascular Medicine at Brigham and Women's Hospital in Boston. They discuss how the inflammation hypothesis of atherosclerosis has been proven by the CANTOS trial and what the future might hold. We trust you'll enjoy the police sirens in the middle of the interview and hope you enjoy the discussion. Link for CANTOS study - http://www.nejm.org/doi/full/10.1056/NEJMoa1707914

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Andrew D'Silva, author of a comprehensive Education in Heart paper about assessing and treating older athletes with heart conditions. Link to published paper: http://heart.bmj.com/content/early/2017/10/30/heartjnl-2016-310744

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Ian Graham, from Trinity College Dublin. Professor Graham is a world authority in preventative cardiology. They discuss the differences in reaching secondary prevention targets amongst men and women in three different areas of the world. Link to published paper: http://heart.bmj.com/content/103/20/1587

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Nick Morrell, a pulmonary hypertension expert from Cambridge, UK. First, they discuss the classification of pulmonary hypertension. They then move on to contemporary patient management and the latest in pulmonary hypertension research. Link to published paper: http://heart.bmj.com/content/102/20/1680 and to Professor Morrell's research lab - https://www.bhf.org.uk/research/our-top-professors/professor-nick-morrell

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Aseem Malhotra from Lister Hospital, Stevenage, UK. They discuss what we should tell our patients about diet and exercise - high fat, low fat or something else? Link to published paper: http://bjsm.bmj.com/content/51/15/1111

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Ronak Rajani from Guy’s and St Thomas’ Hospital, London. They discuss the clinical trials and applications of FFR CT. Link to published paper: http://heart.bmj.com/content/103/15/1216.long

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Shelley Wood, a journalist and managing editor of TCTMD.com. They discuss how to get the most from a medical conference, what’s going to be big at ESC 2017 and why you should always pack your running shoes in your conference bag. Link to TCTMD: https://www.tctmd.com/

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Raja Selvaraj from the Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India. They discuss the pressing need for the reuse of cardiac devices in low and middle income countries and his research in this area. Link to published paper: http://heartasia.bmj.com/content/9/1/59

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Benjamin Levine from UT Southwestern Medical Center, Texas. They discuss the physiological challenges presented by space travel and how astronauts can adapt. And James discovers he could still become an astronaut (at least as far as his heart is concerned) - there’s hope yet! Link to authors details: http://profiles.utsouthwestern.edu/profile/14262/benjamin-levine.html

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Pier Lambiase from Bart's Heart Centre and University College London. They discuss arrhythmia-induced cardiomyopathy - its causes, incidence, treatment and outcomes. Link to published paper: http://heart.bmj.com/content/103/19/1543.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Heart Editor-In-Chief Professor Catherine Otto from Seattle, USA. They discuss actionable steps for getting your research published. Spoiler - it all starts with a good question! Link to published paper: http://heart.bmj.com/content/103/16/1292.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr David Adlam from the University of Leicester. They discuss spontaneous coronary artery dissection (SCAD) - its pathology, aetiology, diagnosis and treatment. Dr Adler is happy to be emailed about adding patients to SCAD registry and to give clinical advice to other physicians. Link to published paper: http://heart.bmj.com/content/early/2017/03/31/heartjnl-2016-310320.info

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Eike Nagel from the Frankfurt Institute for Translational Cardiovascular Imaging. They discuss how cardiac MRI can guide the management of patients with angina, as demonstrated in the MR Inform study, presented as a late-breaking trial at ACC 2017. They also touch on the latest NICE guidelines for management of stable angina. Link to Study: http://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2017/03/16/14/42/MR-INFORM

In this episode of the Heart podcast, Digital Media Editor Dr James Rudd is joined by Dr Jubin Joseph from St Thomas’ Hospital, London. They discuss a new section in Heart, aimed particularly at cardiology trainees and fellows, called Cardiology in Focus. They also highlight the attractiveness of cardiology as a specialty as well as some of the current challenges that it faces.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Adam Timmis from Barts Heart Centre. The UK NICE committee updated their stable chest pain guidelines in 2016 and this was controversial. They discuss the changes in the guidelines since 2010. Link to published paper: heartjnl-2015-308341 http://heart.bmj.com/content/early/2017/04/27/heartjnl-2015-308341

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Paul Cremer from The Cleveland Clinic. They discuss Paul's views, expressed in a Heart Editorial, on the latest NICE guidelines for assessment of stable chest pain. Link to published paper: http://heart.bmj.com/content/early/2017/05/02/heartjnl-2017-311410

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. van Hagen and Professor Roos Hesselink from Erasmus University, Rotterdam. They discuss an approach to managing cardiac emergencies arising during pregnancy, based on their excellent Education in Heart paper linked below. Link to published paper: http://heart.bmj.com/content/103/2/159.long

In this special episode, we bring you three interviews with key people behind clinical decision tools for prediction of pulmonary embolism. This topic is covered in a BMJ Learning module called 'Step by step: how to diagnose pulmonary embolism', which is a practical guide for GPs available at www.learning.bmj.com - direct URL: https://goo.gl/NyN3FQ. The program starts with an interview with Dr Phil Wells, who is the author of the Wells score for deep vein thrombosis and pulmonary embolism. This is followed by a discussion with Dr Gregoire le Gal, author of the paper on age adjusted D-dimer. The last interview is with Dr Jeff Kline, who is the author of the PERC rule. The interviews are conducted by Dr Kerstin de Witt lead author of the BMJ Learning module on how to diagnose a pulmonary embolism.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Amitava Banerjee from Farr Institute, University College London, UK. They discuss established ways of cardiovascular risk prediction but also get distracted by machine learning and electronic health record real-time analytics. Link to published paper: http://heart.bmj.com/content/early/2017/02/24/heartjnl-2016-311141 AND second paper: http://heart.bmj.com/content/early/2017/02/22/heartjnl-2016-310668

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Paulus Kirchhof from University of Birmingham. They discuss the latest ESC guidelines for atrial fibrillation, including the concept of heart teams, catheter ablation and why AF hasn’t be cured yet. Link to published paper: http://heart.bmj.com/content/early/2017/01/11/heartjnl-2016-310843.full

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Giovanni Biglino from the Bristol Heart Institute. They discuss computational modelling in congenital heart disease, including optimal stent selection, new device development and 3D printed handheld models for patient education. http://heart.bmj.com/content/103/2/98.abstract

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Andrew Chapman from the BHF Centre for Cardiovascular Science, University of Edinburgh. They discuss the controversial area of myocardial injury vs. myocardial infarction and delve into unresolved areas in troponin research and clinical application. Link to published paper: http://heart.bmj.com/content/103/1/10

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Prachi Bhatnagar from Oxford, UK. They discuss the changing incidence, prevalence and admission rates for cardiovascular disease amongst UK residents. They also explore possible reasons for the observed results. Link to published paper: http://heart.bmj.com/content/early/2016/07/26/heartjnl-2016-309573.full?sid=5fd48f9a-227a-4c6f-b16e-24e6cb059cdd

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Nik Sabharwal from Oxford Heart Centre, UK. They discuss the very latest developments in nuclear cardiology, including new tracers, updated guidelines and replacing cardiologists with machines!

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Nadia Khan from University of British Columbia in Vancouver. They discuss the incidence of prodromal symptoms before an acute coronary syndrome, the opportunities for medical intervention and how to raise awareness amongst patients and healthcare providers. Full text >> http://heart.bmj.com/content/early/2016/12/13/heartjnl-2016-309945.abstract

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Michelle Williams from university of Edinburgh. They discuss all aspects of cardiac CT - indications, benefits and technical advances.

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Thomas Payne from the University of Seattle, where he is the Chief Medical information Officer with a research interest in electronic Health Records (EHRs). They discuss the state of play of EHRs in the US and beyond, current research and clinical opportunities and a vision of the future. Link to published paper: http://heart.bmj.com/content/early/2016/08/08/heartjnl-2015-308724.abstract

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Ever Grech from South Yorkshire Cardiothoracic Centre, Sheffield, UK. They discuss Dr Grech’s innovative study design, why younger smokers have >8 times the risk of heart attack than older patients and what can be done about this. Read the full article and related editorial here: http://heart.bmj.com/content/early/2016/10/31/heartjnl-2016-309595.full http://heart.bmj.com/content/early/2016/10/31/heartjnl-2016-310687.full

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Professor Catherine Otto from University of Washington School of Medicine, Seattle, USA. They discuss a disruptive new approach to guideline production in cardiology that aims to be agile, responsive and clear about the best approach to a focussed clinical scenario - The Wikirecs approach. Both the BMJ paper describing the Wikirecs production process and the Heart Editorial by Catherine Otto are linked below. Link to paper (1): http://heart.bmj.com/content/early/2016/10/06/heartjnl-2016-310353.extract Link to paper (2): http://www.bmj.com/content/bmj/354/bmj.i5130.full.pdf

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr. Johan Engdahl from the Karolinska Institute in Stockholm, Sweden. He is an expert on screening for atrial fibrillation, and wrote a recent editorial on this subject for Heart http://heart.bmj.com/content/early/2016/08/26/heartjnl-2016-309993.full?sid=32fe2dc0-839f-4ca4-8ed0-0c7360d674a1. They discuss the reasons for AF screening, whom to target and how to do it - including using your smartphone!

In this episode of the Heart podcast, Digital Media Editor Dr. James Rudd is joined by Dr Divaka Perera from St. Thomas' Hospital, London. Divaka recently published an Education in Heart paper entitled "Percutaneous mechanical circulatory support: current concepts and future directions" - http://heart.bmj.com/content/early/2016/08/08/heartjnl-2015-308562.extract They discuss the physiology behind these devices, when they might be used, and the difficulty in producing robust guidelines in this area of cardiology.

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Prof. James Moon. Prof. Moon is director of The Cardiovascular Magnetic Resonance Imaging Unit and The Centre for Rare Cardiovascular Diseases Unit, Barts Heart Centre, St Bartholomew's Hospital, London, UK. His group recently published a review article entitled "Cardiac MRI evaluation of myocardial disease". They discuss the growing impact of MRI for the diagnosis and non-invasive monitoring of many different heart diseases. Link to paper : http://heart.bmj.com/content/early/2016/06/27/heartjnl-2015-309077

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Dr Carlos Iribarren of the Kaiser Permanente Northern California Division of Research, Oakland, California, USA. They discuss his publication entitled "High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults". This time, the discussion ranges from Framingham Risk Scores to Northern Californian earthquakes! Link to paper: http://heart.bmj.com/content/102/15/1177.long

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Dr. Steven Cohn from the University of Miami Miller school of Medicine. Dr. Cohn has recently published an Education in Heart paper entitled "The cardiac consult for patients undergoing non-cardiac surgery". This paper gives an in-depth review of this area of cardiology practice that is familiar to many of us. Dr. Cohn is a leading figure in pre-operative assessment and was a reviewer of the most recent ACC guidelines. Several controversial areas are discussed, including both the use of beta-blockers and revascularisation prior to non-cardiac surgery. Link to paper : http://heart.bmj.com/content/early/2016/06/20/heartjnl-2015-307997.extract

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Professor Marco Roffi from the University Hospital, Geneva. He is the first author of an Education in Heart paper entitled "Carotid Artery Stenting". They discuss how best to identify patients with carotid artery disease, the role of imaging, when to choose stenting vs surgery and the current ESC guidelines in this area. Read the full article: http://heart.bmj.com/content/102/13/1059.

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Dr. Ramzi Khamis, from the National Heart and Lung Institute, Hammersmith Hospital Campus, Imperial College, London, UK. He is the lead author on a recent Education in Heart paper entitled "Gender differences in coronary heart disease". James and Ramzi discuss the complex and under-researched areas that lead to poorer outcomes for females with some forms of heart disease. Read the full article here: http://heart.bmj.com/content/early/2016/04/28/heartjnl-2014-306463.full

In this episode of the Heart podcast, Associate Editor Dr. James Rudd is joined by Professor Viktor Mayer-Schönberger, Professor of Internet Governance and Regulation at Oxford University’s Internet Institute. He is an expert in 'Big Data' and recently delivered the opening keynote lecture at the British Cardiovascular Society's annual meeting in Manchester, entitled ‘Big data: a big deal for cardiology?' Viktor shares his knowledge about how 'Big Data' is rapidly changing the way we do scientific research. Topics range from 'flu prevention using Google searches to predicting the timing of heart attack and stroke. Links http://www.big-data-book.com/ http://eurheartj.oxfordjournals.org/content/37/12/996.long http://www.bcs.com/conference/webcasts1.asp?talkid=5307&confyear=2016

In this episode of the Heart Podcast, Heart associate editor Dr James Rudd is in conversation with Dr Tina Varghese from Emory University, Atlanta. She has written a review paper on "Physical activity in the prevention of coronary heart disease: implications for the clinician". http://heart.bmj.com/content/early/2016/03/03/heartjnl-2015-308773.full In this podcast, they discuss the benefits of regular exercise, how much is too much, how exercise protects your heart and why we aren't good at prescribing exercise for our patients.

In this episode of the Heart podcast, digital media editor Dr James Rudd is joined by Dr Marc Dweck from Edinburgh University. Marc is a BHF Intermediate Fellow and an Honorary Cardiology Consultant who has won many awards for his approach to vascular imaging for risk prediction. As part of the Cardiology in Focus series, Marc shares his pathway into cardiovascular research and discusses its highs and lows. Marc has plenty of tips for those entering or established in a scientific career!

In this episode of the Heart podcast, associate editor Dr James Rudd is joined by Dr Rachel Forsythe, a vascular surgeon from the University of Edinburgh. They discuss her recent review paper, "Monitoring the biological activity of abdominal aortic aneurysms - beyond ultrasound". This common disease still causes considerable morbidity and mortality despite advances in surgical technique, largely because it is difficult to predict aneurysm expansion and rupture. They cover established clinical techniques and finish by highlighting newer approaches involving molecular imaging and targeted contrast agents.

In this edition of the Heart podcast, associate editor Dr. James Rudd sits down with Professor Peter Weissberg, Medical Director of the British Heart Foundation (www.bhf.org.uk/about-us/who-we-are/our-directors). As the largest independent funder of cardiovascular research in the UK (around £100 million annually), Peter has sage advice for young researchers considering a career in cardiovascular science. He looks back at some highlights from his 12 years as Medical Director of the BHF. Finally, Peter explains why there has never been a better time to consider a career in cardiovascular research.

In this edition of the Heart Podcast, associate editor Dr James Rudd chats to Professor Adam Timmis from the Barts Heart Centre, London, UK about his recent publication "A 10-year prognostic model for patients with suspected angina attending a chest pain clinic" http://heart.bmj.com/content/early/2016/02/29/heartjnl-2015-308994.full?sid=bd5e1edf-49cd-4a7d-b2cc-17f0c311890d. They discuss the motivation for his study, debate diagnosis vs. prognosis in angina, and cover how the online prognosis calculator can be applied in the local chest pain clinic. Calculator: https://www.sealedenvelope.com/trials/pisa/

In this episode of the Heart Podcast, Heart associate editor Dr James Rudd is joined by Dr Kaspar Broch of the Oslo University Hospital, Norway to discuss his recent paper in Heart entitled: "Controlled release metoprolol for aortic regurgitation: A randomised clinical trial" They discuss the rationale for beta-blockers in aortic regurgitation and the results of this first clinical trial of these agents. Full paper >> heart.bmj.com/content/102/3/191.…-a075-27b877e18613

Heart digital media editor Dr. James Rudd is joined by Dr Michelle Ploutz from the Department of Pediatric Cardiology, Children’s National Health System, Washington, DC, to discuss her recent paper in Heart, entitled "Handheld echocardiographic screening for rheumatic heart disease by non-experts". They cover using echocardiography, performed by trained local nurses, to diagnose rheumatic heart disease in Uganda. The need for this approach, and how it fared in this study of 1000 African school children are revealed. Read the full article here: http://heart.bmj.com/content/102/1/35.full.