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Show Notes
How is the synovial fluid produced? Who figured it out? It's a ripping yarn involving corpses, cats, anti-hypertensives, steroids and streptococcus.
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- Intro :11
- Today's episode :15
- Synovium 101 :22
- Overview of the synovium and synovial fluid 2:06
- How they figured it out? Dr. Marian Ropes 5:37
- Investigating synovial fluid 7:46
- Cows experiment and where synovial fluid comes from 11:25
- Clinical review of synovial fluid 14:57
- What's inside the fluid? 18:54
- What makes up the fluid? 20:51
- How do things get out of the synovium? 23:19
- How are things absorbed into the synovium? 27:21
- How well do steroids get picked up systemically? 29:39
- Summary 32:30
- Thank you 34:59
Disclosures: Brown reports no relevant financial disclosures.
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References:
Edwards JC. J Anat. 1994;184:493-501.
Rhinelander FW, et al. J Clin Invest. 1939;doi:10.1172/JCI101011.
Shaffer MF, et al. J Exp Med. 1939;doi:10.1084/jem.70.3.293.