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The Inflammasome for Dunces
Season 1 · Episode 24

The Inflammasome for Dunces

Healio Rheuminations · Adam J. Brown, MD

October 1, 201918m 30s

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Show Notes

A quick take on one of the little-appreciated engines of the innate immune system.

  • Intro :10
  • A little about this episode :25
  • The inflammasome is a component of the innate immune system 3:12
  • Remember NLRP3 4:12
  • The toll-like receptors 5:05
  • Triggering the inflammasome 7:05
  • The proteins 8:04
  • A medieval battle and a trebuchet 9:56
  • A disclosure 17:00
  • I hope you enjoyed this episode 18:06

We'd love to hear from you! Send your comments/questions to [email protected]. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Booshehri LM, Hoffman HM. J Clin Immunol. 2019;39:277-286.

Hasudungan A. Immunology – NOD like receptors and the inflammasome [Video]. YouTube. https://www.youtube.com/watch?v=biunM2iD8qM&t=4s. Published March 29, 2015. Accessed September 4, 2019.