FoundMyFitness

CHORI Bar Team Meet some of the CHORI bar team: Dr. Bruce Ames, Dr. Joyce McCann, and Dr. Mark Shigenaga. On this podcast we talk about the different types of HDL and LDL cholesterol and what they do in the body. We discuss a low-calorie, micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that Bruce and I briefly touched on in a previous conversation, how each of the components of the bar from the vitamins and minerals to the fiber and polyphenols are all really important but have separate functions in the body that can work together in much the same way an orchestra play their individual parts to create a symphony that is larger than their individual roles, how the chori bar raised a certain type of HDL in lead adults in just two weeks, how eating the CHORI bar raised HDL, lowered triglycerides and small LDL particles, and improved insulin sensitivity after eight weeks in overweight/obese individuals all without them changing their diet. The CHORI bar is not available for consumers yet but you can keep up with choribar updates on bruceames.org/choribar. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Aubrey de Grey Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS research foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. In this episode, we discuss... 00:00:00 - Introduction 00:02:27 - How to understand aging 00:08:14 - Epigenetic modifications accommodate cellular aging 00:18:24 - Inflammation is a double-edged sword 00:24:00 - Parabiosis has the potential to slow aging 00:31:35 - Lifestyle factors can only extend lifespan so far 00:36:49 - Future of Crispr/Cas9 in aging research 00:40:56 - Utilizing pluripotent stem cells from the placenta You can find Aubrey on Twitter at @aubreydegrey, and his foundation at www.sens.org. If you're interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/aubrey-de-grey Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Rhonda Patrick answers some of the most popular questions regarding vitamin D including: (00:00) Introduction (02:22) How do you decide how much vitamin D to supplement with? (12:51) Is it possible to get too much vitamin D? (20:52) Is there a difference between vitamin D made from the sun versus a supplement? (24:43) What form of vitamin D is more bioavailable or absorbed better? Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dan Pardi Dr. Dan Pardi researches sleep neurobiology and is a co-founder of Dan's Plan, an online wellness and technology company. In this episode, we discuss... (00:00) Introduction (03:27) Circadian rhythms are key to health (07:07) Artificial lights suppress melatonin production (12:04) Sleep clears toxins from the brain (16:14) Sleep deprivation increases appetite and decreases energy expenditure (24:09) Sleep is critical for creating long-term memories (31:29) Blue light can reset circadian rhythm in the Antarctic winter (36:57) Long-term exercise improves sleep quality in women (44:43) Sleep deprivation worsens decision-making (51:02) Practices that encourage healthy sleep (53:57) A healthy diet supports good sleep (59:59) Dan's plan bridges the gap between research and your personal health Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Tim Ferriss Tim Ferris is a notorious self-experimenter, three-time New York Times bestselling author, angel investor, startup advisor, and much, much, much more. In this episode, we discuss... (00:00) Introduction (02:29) Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation (05:54) Tim's self-experimentation with the ketogenic diet and the biomarkers he measures daily (14:55) Can a ketogenic diet reduce Alzheimer's disease risk? (22:14) Inflammation accelerates aging, but is necessary for tissue repair (26:17) Vitamin C reduces inflammation, but may also inhibit muscle growth (35:22) Tim describes his experience with Lyme disease (45:43) Rhonda talks about her experience with MRSA and antibiotics (48:55) Tim's personal experience with ketosis (55:06)The 4-Hour Body talks about improving your body's performance while doing less (01:02:56) How to reduce social stress by exposing yourself to similar stresses (01:09:52) Meditation can help you stay focused and improve production (01:12:40) Tim Ferriss' future plans in Hollywood If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Jim Kean Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX. In this podcast Rhonda and Jim discuss the quantified self movement and the importance of measuring biomarkers more than once, the gut's role in cholesterol and serotonin in the gut versus in the brain, about the role of exercise in preventing neuroinflammation and the effects of overtraining on sex hormones. We also chat a bit about the psychology of constructing a new, non-gender segregated, team spectator sport and bringing it to market, the factors that separate a professional spectator sport from any other form of entertainment: including patriotism, justice, and vicariousness, the mathematical nature of the sport and the floor coach's role in monitoring athletes before they start "redlining," how NPGL teams may find new ways to tune their gameplay and find an edge on the competition in the future by stepping up the use of more advanced athlete-level analytics. In this episode, we discuss... (00:00) Introduction (01:11) Optimizing performance and health has become more accessible (07:18) Frequent blood tests helped Jim find his optimal level of Vitamin D (09:45) Jim's habits for optimizing insulin sensitivity and lean body mass (11:06) Exercise reduces inflammation caused by kynurenine (12:16) Exercise increases BCAA uptake by muscle, increasing serotonin in the brain (13:33) Jim Kean introduces the book, Grain Brain (14:32) Dysfunctional insulin receptors are found in Alzheimer's disease (16:11) Endotoxin reacts with LDL cholesterol to form heart disease-promoting foam cells (19:09) How you make a successful sport (29:13) What is overtraining in cross-fit and what are the consequences? If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Bruce Ames Dr. Rhonda Patrick speaks with Dr. Bruce Ames, about a micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that was developed in the Ames laboratory. The bar was formulated to be moderate in calories (107 kcal/≈25 g bar), but nutrient dense, with a polyphenolic-rich matrix of fruit, walnuts, and non-alkali-processed dark chocolate, supplemental vitamins, minerals, docosahexaenoic acid (DHA), a blend of insoluble and soluble fibers, protein, and glutamine. Most vitamins and minerals are present in amounts representing 10 to 50% of their corresponding recommended daily allowance (RDA) per bar; with the exceptions of vitamin D and vitamin C (both added above 50% RDA). The goal was not to meet the RDA in every case but to complement standard dietary intakes by consumption of 2 bars each day. People that ate the bar were told not to change their diets but just to eat the bars on top of their normal diet. Lean people that ate the CHORI bar twice a day were able to raise HDL, lower homocysteine, and raise glutathione in just two weeks. Overweight/obese people with low inflammation that ate the bar showed weight loss after 8 weeks, raised their HDL, lowered triglycerides and small LDL particles, and improved insulin sensitivity. Overweight/obese people that had high inflammation were able to lower their inflammation after 2 weeks of eating the bar and raise their HDL after 8 weeks. If you're interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/choribar-weight-loss Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. Bruce Ames In this podcast, Dr. Rhonda Patrick interviews her mentor, Dr. Bruce Ames, about his triage theory and other nutrition topics. Dr. Ames was the 23rd most-cited scientist between 1973 and 1984, which is evidence of his long and productive career investigating human health and disease. Dr. Ames continues his research expanding our knowledge of nutrients such as vitamin D and its role in Autism spectrum disorder. In this episode, we discuss... (00:00) Introduction (04:18) Dr. Ames discovers vitamin deficiency-induced DNA damage (10:35) Triage theory explains nutrient rationing (14:37) Nutrient deficiencies cause insidious damage and accelerate aging (25:25) Expanding the list of essential vitamins (e.g., lutein & zeaxanthin) (31:05) A Western diet pattern is mostly empty calories (36:46) Challenges running randomized double-blind clinical trials in nutrition (38:12) Nutrition is not the focus of our current healthcare system (42:15) Dr. Ames' philosophy about healthy and delicious foods If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information on triage theory, longevity & micronutrients straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this interview, Dr. Rhonda Patrick talks to Dr. Frans Kuypers about his lab's discovery on how the human placenta is a rich source of pluripotent stem cells, and yet the placenta is thrown away after delivery. In this episode, we discuss... (00:00) Introduction (04:39) The human placenta as a source of hematopoietic cells (11:30) Pluripotent cells can differentiate into any cell in the human body (13:03) Public banking of abundant pluripotent placental stem cells (18:06) Therapeutic applications of stem cells (22:56) Stem cells as part of a physician's toolkit (28:56) Epigenetics of induced pluripotent stem cells (34:49) Biogenerators could use young cells to produce growth factors and other chemicals (38:36) Transferring blood from young mice into old mice regenerates tissues using GDF11 (43:32) Opportunities and challenges of banking stem cells (52:49) Stem cells could eliminate deaths due to lack of bone marrow donors (56:37) The way we fund research isn't optimal for society If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

Dr. George A Brooks Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others. In this episode, we discuss... (00:00) Introduction (01:40) Dr. Brooks' experience as an athlete inspired his research on lactate (06:50) Lactate and its relationship to muscle fatigue is misunderstood (09:10) Adaptations to exercise improve mitochondrial functioning and lactate metabolism (14:14) How to use lactate threshold training to improve performance (23:49) Lactate improves brain health and cognitive function (26:45) Lactate improves outcomes of traumatic brain injury via metabolism (30:00) Lactate spares glucose, increasing antioxidants such as glutathione (42:50) Early lactate administration following a traumatic brain injury is necessary, but challenging (48:20) Lactate from exercise improves Parkinson's disease (55:00) Brain metabolism following traumatic brain injury If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor

In this episode Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles. She identified vitamins/minerals and other compounds present in vegetables/fruits that are essential for mitochondrial health, which is critical for brain function. In this episode, we discuss... (00:00) Introduction (00:48) Dysfunctional mitochondria contribute to disease development (04:03) Suboptimal magnesium status is common and possibly dangerous (04:50) Green vegetable consumption is key to Dr. Walhs' wellness (06:18) The Triage theory explains how low micronutrient intake increases aging-related diseases (09:20) Fruits and vegetables are color-coded for the variety of micronutrients needed in our diet (10:35) Sulfur, found in garlic, onions, and cruciferous vegetables, is needed for mitochondrial function (16:55) Dr. Wahls' protocol of diet, supplements, and exercise improves fatigue in MS If you're interested in learning more, you can read the full show notes here. Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/crowdsponsor