Podcast #448: Chronic Salicylate Toxicity

Emergency Medical Minute · medicalminute

March 23, 20192m 51s

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Show Notes

Author: Ryan Circh, MD

Educational Pearls:

Chronic salicylate (ASA) toxicity can present in elderly patients as altered mental status
Consider chronic toxicity in patients with an unexplained anion gap acidosis
Treatment for chronic ingestion typically includes IV fluids and urine alkalinization

References:

O'Malley GF. Emergency department management of the salicylate-poisoned patient. Emerg Med Clin North Am. 2007 May;25(2):333-46; abstract viii. Review. PubMed PMID: 17482023.

Durnas C, Cusack BJ. Salicylate intoxication in the elderly. Recognition and recommendations on how to prevent it. Drugs Aging. 1992 Jan-Feb;2(1):20-34. Review. PubMed PMID: 1554971.

Summarized by Will Dewsipelaere, MS3 | Edited by Erik Verzemnieks, MD

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